Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Zymeworks Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 96
- +6 vs. Q3 2022
- Shares held
- 57.2M
- +9.76M (+20.6%) vs. Q3 2022
- Total value
- $449.9M
- +$157.9M (+54.1%) vs. Q3 2022
- New holders
- 33
- 31 more added
- Sold out
- 27
- 17 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 11 | $0 | 0.00% | 00.0% | Unchanged |
| Asset Dedication, LLC | 47 | $0 | 0.00% | +47 | New |
| CoreCap Advisors, LLC | 18 | $141 | 0.00% | +18 | New |
| UBS Group AG | 25 | $197 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 100 | $786 | 0.00% | +100 | New |
| Eagle Bay Advisors LLC | 110 | $865 | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 96 | $987 | 0.00% | −375−79.6% | Reduced |
| Steward Partners Investment Advisory, LLC | 158 | $1.24K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 280 | $2.20K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 350 | $2.75K | 0.00% | +350 | New |
| Stonehage Fleming Financial Services Holdings Ltd | 550 | $4.32K | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 869 | $6.83K | 0.00% | −122,458−99.3% | Reduced |
| IFP Advisors, Inc | 600 | $8.00K | 0.00% | +300+100.0% | Added |
| Rockefeller Capital Management L.P. | 1,500 | $11.0K | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 1,650 | $13.0K | 0.00% | +1,650 | New |
| Cutler Group LP | 3,000 | $23.0K | 0.00% | +200+7.1% | Added |
| Tower Research Capital LLC (TRC) | 3,276 | $26.0K | 0.00% | +3,276 | New |
| Compagnie Lombard Odier SCmA | 10,000 | $79.0K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 12,832 | $100.9K | 0.00% | −1,403−9.9% | Reduced |
| Alpine Global Management, LLC | 13,046 | $103.0K | 0.03% | +13,046 | New |
| Russell Investments Group, Ltd. | 14,144 | $111.2K | 0.00% | −39,611−73.7% | Reduced |
| Forefront Wealth Management Inc. | 13,400 | $127.8K | 0.17% | +13,400 | New |
| Lazard Asset Management LLC | 17,628 | $138.0K | 0.00% | 00.0% | Unchanged |
| Man Group plc | 18,289 | $143.8K | 0.00% | −142,256−88.6% | Reduced |
| Virtus ETF Advisers LLC | 21,818 | $171.5K | 0.09% | +3,838+21.3% | Added |
| Engineers Gate Manager LP | 22,320 | $175.4K | 0.01% | +22,320 | New |
| Walleye Trading LLC | 24,378 | $191.6K | 0.00% | +8,864+57.1% | Added |
| Commonwealth Equity Services, LLC | 25,744 | $202.0K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 25,858 | $203.2K | 0.00% | +25,810+53,770.8% | Added |
| Gsa Capital Partners LLP | 27,863 | $219.0K | 0.03% | +27,863 | New |
| Group One Trading, L.P. | 27,939 | $219.6K | 0.01% | −14,613−34.3% | Reduced |
| Bank of America Corp | 28,107 | $220.9K | 0.00% | +25,321+908.9% | Added |
| Journey Strategic Wealth LLC | 28,846 | $226.7K | 0.03% | 00.0% | Unchanged |
| LMR Partners LLP | 29,224 | $229.7K | 0.01% | +29,224 | New |
| Parallax Volatility Advisers, L.P. | 30,000 | $235.8K | 0.01% | 00.0% | Unchanged |
| Jump Financial, LLC | 31,887 | $250.6K | 0.01% | +31,887 | New |
| Susquehanna Fundamental Investments, LLC | 31,930 | $251.0K | 0.00% | +31,930 | New |
| Bank of Montreal | 36,779 | $289.1K | 0.00% | −10,341−21.9% | Reduced |
| Two Sigma Investments, LP | 37,712 | $296.4K | 0.00% | +37,712 | New |
| Allspring Global Investments Holdings, LLC | 38,299 | $301.0K | 0.00% | −5,628−12.8% | Reduced |
| Stifel Financial Corp | 39,800 | $312.8K | 0.00% | +39,800 | New |
| Voloridge Investment Management, LLC | 41,821 | $328.7K | 0.00% | −248,789−85.6% | Reduced |
| Simplex Trading, LLC | 48,192 | $378.0K | 0.02% | +13,122+37.4% | Added |
| Invesco Ltd. | 51,180 | $402.3K | 0.00% | −258−0.5% | Reduced |
| AlphaCentric Advisors LLC | 52,500 | $412.6K | 0.41% | +52,500 | New |
| Cubist Systematic Strategies, LLC | 54,730 | $430.2K | 0.00% | +46,206+542.1% | Added |
| Envestnet Asset Management Inc | 56,165 | $441.5K | 0.00% | +56,165 | New |
| Raymond James Financial Services Advisors, Inc. | 56,448 | $443.7K | 0.00% | −16,076−22.2% | Reduced |
| Stephens Inc | 56,647 | $445.2K | 0.01% | +56,647 | New |
| Janney Montgomery Scott LLC | 58,832 | $462.0K | 0.00% | +6,456+12.3% | Added |
| North Growth Management Ltd. | 75,000 | $591.0K | 0.13% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 78,425 | $616.4K | 0.02% | +310.0% | Added |
| Advisor Group Holdings, Inc. | 85,083 | $669.0K | 0.00% | +84,983+84,983.0% | Added |
| Susquehanna International Group, LLP | 94,228 | $740.6K | 0.00% | −87,519−48.2% | Reduced |
| Wells Fargo & Company | 101,333 | $796.5K | 0.00% | −7,593−7.0% | Reduced |
| State Street Corp | 101,985 | $801.6K | 0.00% | +2,622+2.6% | Added |
| Millennium Management LLC | 115,522 | $908.0K | 0.00% | −77,106−40.0% | Reduced |
| Thrivent Financial for Lutherans | 117,092 | $919.0K | 0.00% | +101,010+628.1% | Added |
| Caxton Associates LP | 119,139 | $936.4K | 0.07% | +119,139 | New |
| Renaissance Technologies LLC | 120,000 | $943.0K | 0.00% | +62,223+107.7% | Added |
| Candriam Luxembourg S.C.A. | 120,305 | $945.6K | 0.01% | +120,305 | New |
| Goldman Sachs Group Inc | 125,057 | $982.9K | 0.00% | +125,057 | New |
| Ci Investments Inc. | 147,170 | $1.16M | 0.01% | +700+0.5% | Added |
| Raymond James & Associates | 154,152 | $1.21M | 0.00% | −11,781−7.1% | Reduced |
| Royal Bank of Canada | 168,417 | $1.32M | 0.00% | +134,535+397.1% | Added |
| Sectoral Asset Management Inc | 192,124 | $1.51M | 0.29% | +192,124 | New |
| Picton Mahoney Asset Management | 259,004 | $2.04M | 0.11% | +154,599+148.1% | Added |
| 683 Capital Management, LLC | 290,000 | $2.28M | 0.21% | +290,000 | New |
| Mariner, LLC | 357,650 | $2.81M | 0.01% | +357,650 | New |
| D. E. Shaw & Co., Inc. | 369,187 | $2.90M | 0.00% | +280,710+317.3% | Added |
| Platinum Investment Management Ltd | 395,920 | $3.11M | 0.12% | +21,928+5.9% | Added |
| Tang Capital Management LLC | 400,000 | $3.14M | 0.46% | +400,000 | New |
| Timelo Investment Management Inc. | 404,726 | $3.18M | 3.13% | +500+0.1% | Added |
| Tejara Capital Ltd | 406,376 | $3.19M | 1.86% | +406,376 | New |
| Artal Group S.A. | 450,000 | $3.54M | 0.20% | 00.0% | Unchanged |
| Monaco Asset Management SAM | 500,000 | $3.93M | 1.40% | +500,000 | New |
| Woodline Partners LP | 600,403 | $4.72M | 0.07% | −953,679−61.4% | Reduced |
| Frazier Life Sciences Management, L.P. | 610,000 | $4.79M | 0.30% | +610,000 | New |
| BlackRock Inc. | 676,407 | $5.32M | 0.00% | +94,698+16.3% | Added |
| Deutsche Bank AG | 715,440 | $5.62M | 0.00% | +623,781+680.5% | Added |
| Granahan Investment Management Inc | 738,448 | $5.80M | 0.18% | +150,640+25.6% | Added |
| Sessa Capital IM, L.P. | 740,878 | $5.82M | 0.36% | +740,878 | New |
| Brookfield Asset Management Inc. | 741,186 | $5.83M | 0.02% | +537,534+263.9% | Added |
| Point72 Asset Management, L.P. | 749,500 | $5.89M | 0.02% | +505,500+207.2% | Added |
| Farallon Capital Management, L.L.C. | 1,500,000 | $11.8M | 0.08% | +1,500,000 | New |
| Samsara BioCapital, LLC | 1,620,687 | $12.7M | 2.74% | +649,700+66.9% | Added |
| Baker Bros. Advisors LP | 1,708,472 | $13.4M | 0.08% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,291,807 | $18.0M | 0.06% | +782,770+51.9% | Added |
| Credit Suisse AG | 2,439,095 | $19.2M | 0.02% | −1,277−0.1% | Reduced |
| Vanguard Group Inc | 2,536,395 | $19.9M | 0.00% | +2,012,412+384.1% | Added |
| Rubric Capital Management LP | 3,018,217 | $23.7M | 1.04% | +3,018,217 | New |
| Perceptive Advisors LLC | 4,511,275 | $35.5M | 1.02% | +111,176+2.5% | Added |
| Morgan Stanley | 5,573,380 | $43.8M | 0.00% | +314,405+6.0% | Added |
| BVF Inc | 5,870,000 | $46.1M | 1.95% | +5,870,000 | New |
| Redmile Group, LLC | 6,175,918 | $48.5M | 1.99% | +410,100+7.1% | Added |
| EcoR1 Capital, LLC | 7,568,573 | $59.5M | 1.81% | +7,568,573 | New |
| Armistice Capital, LLC | 0 | $0 | 0.00% | −5,785,000−100.0% | Sold out |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −5,380,200−100.0% | Sold out |
| Camber Capital Management LP | 0 | $0 | 0.00% | −2,865,000−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −1,502,720−100.0% | Sold out |