Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Zymeworks Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 182
- −2 vs. Q1 2025
- Shares held
- 75.6M
- +5.10M (+7.2%) vs. Q1 2025
- Total value
- $949.0M
- +$109.0M (+13.0%) vs. Q1 2025
- New holders
- 28
- 63 more added
- Sold out
- 30
- 55 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ikarian Capital, LLC | 25,000 | $313.8K | 0.10% | +25,000 | New |
| Intech Investment Management LLC | 23,163 | $290.7K | 0.00% | −17,100−42.5% | Reduced |
| Duncan Williams Asset Management, LLC | 22,095 | $277.3K | 0.09% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 22,035 | $276.5K | 0.00% | −15,789−41.7% | Reduced |
| Graham Capital Management, L.P. | 21,660 | $271.8K | 0.01% | +21,660 | New |
| Mackenzie Financial Corp | 21,355 | $268.0K | 0.00% | +21,355 | New |
| Manufacturers Life Insurance Company, The | 19,070 | $239.3K | 0.00% | −1,390−6.8% | Reduced |
| Engineers Gate Manager LP | 18,941 | $237.7K | 0.00% | +6,542+52.8% | Added |
| Janus Henderson Group PLC | 18,200 | $228.5K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 15,340 | $192.5K | 0.00% | 00.0% | Unchanged |
| Campbell & CO Investment Adviser LLC | 14,985 | $188.1K | 0.01% | +14,985 | New |
| Voya Investment Management LLC | 14,887 | $186.8K | 0.00% | −766−4.9% | Reduced |
| Envestnet Asset Management Inc | 14,606 | $183.3K | 0.00% | −34,906−70.5% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 14,300 | $179.5K | 0.00% | +14,300 | New |
| Ieq Capital, LLC | 14,169 | $177.8K | 0.00% | +14,169 | New |
| Quest Partners LLC | 14,026 | $176.0K | 0.02% | −17,650−55.7% | Reduced |
| China Universal Asset Management Co., Ltd. | 13,996 | $175.7K | 0.02% | +180+1.3% | Added |
| New York State Common Retirement Fund | 13,371 | $167.8K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 12,665 | $158.9K | 0.00% | −2,247−15.1% | Reduced |
| Jane Street Group, LLC | 12,549 | $157.5K | 0.00% | −123,214−90.8% | Reduced |
| Magnetar Financial LLC | 12,168 | $152.7K | 0.00% | −280−2.2% | Reduced |
| Cresset Asset Management, LLC | 12,153 | $152.5K | 0.00% | −9,167−43.0% | Reduced |
| Quantinno Capital Management LP | 11,746 | $147.4K | 0.00% | −2,499−17.5% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 11,669 | $146.4K | 0.00% | 00.0% | Unchanged |
| Janney Montgomery Scott LLC | 11,567 | $145.0K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 11,159 | $140.0K | 0.00% | −687−5.8% | Reduced |
| Brevan Howard Capital Management LP | 10,628 | $133.4K | 0.00% | +10,628 | New |
| James Investment Research Inc | 10,578 | $132.8K | 0.02% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 10,368 | $130.1K | 0.00% | −800−7.2% | Reduced |
| BNP Paribas Arbitrage, SA | 10,307 | $129.4K | 0.00% | +6,307+157.7% | Added |
| TPG Financial Advisors, LLC | 10,017 | $125.7K | 0.05% | 00.0% | Unchanged |
| Northwest & Ethical Investments L.P. | 10,030 | $125.1K | 0.00% | 00.0% | Unchanged |
| Shell Asset Management Co | 9,296 | $117.0K | 0.00% | −2,805−23.2% | Reduced |
| SG Americas Securities, LLC | 8,671 | $109.0K | 0.00% | −89,494−91.2% | Reduced |
| CWM, LLC | 8,570 | $108.0K | 0.00% | +6,271+272.8% | Added |
| KLP Kapitalforvaltning AS | 7,300 | $91.6K | 0.00% | −3,000−29.1% | Reduced |
| Virtus Investment Advisers, Inc. | 7,178 | $90.1K | 0.03% | −5,828−44.8% | Reduced |
| Simplex Trading, LLC | 6,445 | $80.0K | 0.00% | +2,277+54.6% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 6,311 | $79.2K | 0.01% | +6,311 | New |
| Ameritas Investment Partners, Inc. | 5,616 | $70.5K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 5,000 | $62.8K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 4,947 | $62.1K | 0.00% | +1,131+29.6% | Added |
| DekaBank Deutsche Girozentrale | 3,843 | $48.0K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 3,110 | $39.0K | 0.00% | −9,720−75.8% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,692 | $33.8K | 0.00% | +362+15.5% | Added |
| Amalgamated Bank | 1,880 | $24.0K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,763 | $22.1K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 968 | $12.1K | 0.00% | +636+191.6% | Added |
| Federation des caisses Desjardins du Quebec | 870 | $10.9K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 810 | $10.2K | 0.00% | +267+49.2% | Added |
| Advisor Group Holdings, Inc. | 669 | $8.38K | 0.00% | +264+65.2% | Added |
| Caitong International Asset Management Co., Ltd | 564 | $7.08K | 0.01% | +564 | New |
| National Bank of Canada | 472 | $5.92K | 0.00% | −52−9.9% | Reduced |
| The PNC Financial Services Group, Inc. | 338 | $4.24K | 0.00% | +108+47.0% | Added |
| Parallel Advisors, LLC | 329 | $4.13K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 286 | $4.00K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 309 | $3.88K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 311 | $3.85K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 280 | $3.51K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 248 | $3.11K | 0.00% | −175−41.4% | Reduced |
| EverSource Wealth Advisors, LLC | 181 | $2.27K | 0.00% | +168+1,292.3% | Added |
| Allworth Financial LP | 122 | $1.53K | 0.00% | +12+10.9% | Added |
| Sterling Capital Management LLC | 119 | $1.49K | 0.00% | −822−87.4% | Reduced |
| Skopos Labs, Inc. | 111 | $1.39K | 0.00% | −178−61.6% | Reduced |
| Group One Trading, L.P. | 100 | $1.25K | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 96 | $1.21K | 0.00% | +96 | Added |
| Point72 (DIFC) Ltd | 77 | $966 | 0.00% | +77 | New |
| Kilter Group LLC | 66 | $829 | 0.00% | +66 | New |
| Rothschild Investment LLC | 55 | $690 | 0.00% | −45−45.0% | Reduced |
| Steward Partners Investment Advisory, LLC | 53 | $665 | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 51 | $641 | 0.00% | +51 | New |
| Bare Financial Services, Inc | 45 | $565 | 0.00% | +45 | New |
| Cornerstone Planning Group LLC | 35 | $439 | 0.00% | +35 | New |
| Farther Finance Advisors, LLC | 25 | $314 | 0.00% | −114−82.0% | Reduced |
| Ameriflex Group, Inc. | 20 | $247 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 18 | $226 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 14 | $176 | 0.00% | +14 | New |
| Essential Partners LLC | 14 | $176 | 0.00% | +14 | New |
| SBI Securities Co., Ltd. | 10 | $126 | 0.00% | 00.0% | Unchanged |
| Innovative Advisory Group, LLC | 8 | $100 | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 7 | $88 | 0.00% | −13−65.0% | Reduced |
| Covestor Ltd | 26 | $0 | 0.00% | −1−3.7% | Reduced |
| Bridgeway Capital Management, LLC | 0 | $0 | 0.00% | −766,944−100.0% | Sold out |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −400,000−100.0% | Sold out |
| Empowered Funds, LLC | 0 | $0 | 0.00% | −360,044−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −247,959−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −114,156−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −95,394−100.0% | Sold out |
| Aquilo Capital Management, LLC | 0 | $0 | 0.00% | −84,482−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −41,607−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −32,160−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −26,719−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −21,900−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −17,090−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −12,102−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −12,040−100.0% | Sold out |
| One Wealth Advisors, LLC | 0 | $0 | 0.00% | −10,404−100.0% | Sold out |
| Exchange Traded Concepts, LLC | 0 | $0 | 0.00% | −10,126−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −3,787−100.0% | Sold out |