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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Zymeworks Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
182
−2 vs. Q1 2025
Shares held
75.6M
+5.10M (+7.2%) vs. Q1 2025
Total value
$949.0M
+$109.0M (+13.0%) vs. Q1 2025
New holders
28
63 more added
Sold out
30
55 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 182 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ2 2025: $949.0M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q1 2025.

Institutions holding ZYME in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd26$00.00%−1−3.7%Reduced
True Wealth Design, LLC7$880.00%−13−65.0%Reduced
Innovative Advisory Group, LLC8$1000.00%00.0%Unchanged
SBI Securities Co., Ltd.10$1260.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co14$1760.00%+14New
Essential Partners LLC14$1760.00%+14New
CoreCap Advisors, LLC18$2260.00%00.0%Unchanged
Ameriflex Group, Inc.20$2470.00%00.0%Unchanged
Farther Finance Advisors, LLC25$3140.00%−114−82.0%Reduced
Cornerstone Planning Group LLC35$4390.00%+35New
Bare Financial Services, Inc45$5650.00%+45New
UMA Financial Services, Inc.51$6410.00%+51New
Steward Partners Investment Advisory, LLC53$6650.00%00.0%Unchanged
Rothschild Investment LLC55$6900.00%−45−45.0%Reduced
Kilter Group LLC66$8290.00%+66New
Point72 (DIFC) Ltd77$9660.00%+77New
IFP Advisors, Inc96$1.21K0.00%+96Added
Group One Trading, L.P.100$1.25K0.00%00.0%Unchanged
Skopos Labs, Inc.111$1.39K0.00%−178−61.6%Reduced
Sterling Capital Management LLC119$1.49K0.00%−822−87.4%Reduced
Allworth Financial LP122$1.53K0.00%+12+10.9%Added
EverSource Wealth Advisors, LLC181$2.27K0.00%+168+1,292.3%Added
US Bancorp248$3.11K0.00%−175−41.4%Reduced
HighMark Wealth Management LLC280$3.51K0.00%00.0%Unchanged
TD Waterhouse Canada Inc.311$3.85K0.00%00.0%Unchanged
Truvestments Capital LLC309$3.88K0.00%00.0%Unchanged
Daiwa Securities Group Inc.286$4.00K0.00%00.0%Unchanged
Parallel Advisors, LLC329$4.13K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.338$4.24K0.00%+108+47.0%Added
National Bank of Canada472$5.92K0.00%−52−9.9%Reduced
Caitong International Asset Management Co., Ltd564$7.08K0.01%+564New
Advisor Group Holdings, Inc.669$8.38K0.00%+264+65.2%Added
GAMMA Investing LLC810$10.2K0.00%+267+49.2%Added
Federation des caisses Desjardins du Quebec870$10.9K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC968$12.1K0.00%+636+191.6%Added
GF Fund Management Co. Ltd.1,763$22.1K0.00%00.0%Unchanged
Amalgamated Bank1,880$24.0K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,692$33.8K0.00%+362+15.5%Added
FMR LLC3,110$39.0K0.00%−9,720−75.8%Reduced
DekaBank Deutsche Girozentrale3,843$48.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)4,947$62.1K0.00%+1,131+29.6%Added
Clearstead Advisors, LLC5,000$62.8K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.5,616$70.5K0.00%00.0%Unchanged
Point72 Asia (Singapore) Pte. Ltd.6,311$79.2K0.01%+6,311New
Simplex Trading, LLC6,445$80.0K0.00%+2,277+54.6%Added
Virtus Investment Advisers, Inc.7,178$90.1K0.03%−5,828−44.8%Reduced
KLP Kapitalforvaltning AS7,300$91.6K0.00%−3,000−29.1%Reduced
CWM, LLC8,570$108.0K0.00%+6,271+272.8%Added
SG Americas Securities, LLC8,671$109.0K0.00%−89,494−91.2%Reduced
Shell Asset Management Co9,296$117.0K0.00%−2,805−23.2%Reduced
Northwest & Ethical Investments L.P.10,030$125.1K0.00%00.0%Unchanged
TPG Financial Advisors, LLC10,017$125.7K0.05%00.0%Unchanged
BNP Paribas Arbitrage, SA10,307$129.4K0.00%+6,307+157.7%Added
Teacher Retirement System of Texas10,368$130.1K0.00%−800−7.2%Reduced
James Investment Research Inc10,578$132.8K0.02%00.0%Unchanged
Brevan Howard Capital Management LP10,628$133.4K0.00%+10,628New
Arizona State Retirement System11,159$140.0K0.00%−687−5.8%Reduced
Janney Montgomery Scott LLC11,567$145.0K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey11,669$146.4K0.00%00.0%Unchanged
Quantinno Capital Management LP11,746$147.4K0.00%−2,499−17.5%Reduced
Cresset Asset Management, LLC12,153$152.5K0.00%−9,167−43.0%Reduced
Magnetar Financial LLC12,168$152.7K0.00%−280−2.2%Reduced
Jane Street Group, LLC12,549$157.5K0.00%−123,214−90.8%Reduced
ProShare Advisors LLC12,665$158.9K0.00%−2,247−15.1%Reduced
New York State Common Retirement Fund13,371$167.8K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.13,996$175.7K0.02%+180+1.3%Added
Quest Partners LLC14,026$176.0K0.02%−17,650−55.7%Reduced
Ieq Capital, LLC14,169$177.8K0.00%+14,169New
Universal- Beteiligungs- und Servicegesellschaft mbH14,300$179.5K0.00%+14,300New
Envestnet Asset Management Inc14,606$183.3K0.00%−34,906−70.5%Reduced
Voya Investment Management LLC14,887$186.8K0.00%−766−4.9%Reduced
Campbell & CO Investment Adviser LLC14,985$188.1K0.01%+14,985New
State Board of Administration of Florida Retirement System15,340$192.5K0.00%00.0%Unchanged
Janus Henderson Group PLC18,200$228.5K0.00%00.0%Unchanged
Engineers Gate Manager LP18,941$237.7K0.00%+6,542+52.8%Added
Manufacturers Life Insurance Company, The19,070$239.3K0.00%−1,390−6.8%Reduced
Mackenzie Financial Corp21,355$268.0K0.00%+21,355New
Graham Capital Management, L.P.21,660$271.8K0.01%+21,660New
State of Wisconsin Investment Board22,035$276.5K0.00%−15,789−41.7%Reduced
Duncan Williams Asset Management, LLC22,095$277.3K0.09%00.0%Unchanged
Intech Investment Management LLC23,163$290.7K0.00%−17,100−42.5%Reduced
Ikarian Capital, LLC25,000$313.8K0.10%+25,000New
Ritholtz Wealth Management25,235$316.7K0.01%−35,259−58.3%Reduced
Creative Planning25,389$318.6K0.00%+13,567+114.8%Added
Landscape Capital Management, L.L.C.26,667$334.7K0.03%+26,667New
Price T Rowe Associates Inc26,816$337.0K0.00%+2,703+11.2%Added
Mirae Asset Global ETFs Holdings Ltd.26,863$337.1K0.00%−5,522−17.1%Reduced
Massachusetts Financial Services Co27,109$340.2K0.00%+334+1.2%Added
Bank of Montreal27,642$346.9K0.00%+1,730+6.7%Added
Russell Investments Group, Ltd.28,312$355.3K0.00%+25,259+827.4%Added
Journey Strategic Wealth LLC29,040$364.5K0.01%+99+0.3%Added
Zurcher Kantonalbank (Zurich Cantonalbank)29,934$375.7K0.00%+5,403+22.0%Added
XTX Topco Ltd31,021$389.3K0.02%+10,816+53.5%Added
American Century Companies Inc31,147$390.9K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC32,170$404.0K0.00%−5,472−14.5%Reduced
HRT Financial LP32,758$411.0K0.00%−32,622−49.9%Reduced
MetLife Investment Management33,309$418.0K0.00%00.0%Unchanged
Panagora Asset Management Inc33,559$421.2K0.00%+33,559New
Tudor Investment Corp Et Al34,293$430.4K0.00%+34,293New
Victory Capital Management Inc34,610$434.4K0.00%−9,660−21.8%Reduced