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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Zymeworks Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
114
−7 vs. Q3 2021
Shares held
42.3M
+5.53M (+15.0%) vs. Q3 2021
Total value
$693.9M
−$374.9M (−35.1%) vs. Q3 2021
New holders
22
43 more added
Sold out
29
26 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 114 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ4 2021: $693.9M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2021.

Institutions holding ZYME in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Armistice Capital, LLC1,250,197$20.5M0.50%−1,273,803−50.5%Reduced
Franklin Resources Inc1,257,090$20.6M0.01%+560.0%Added
Woodline Partners LP1,258,401$20.6M0.30%+1,258,401New
Baker Bros. Advisors LP1,708,472$28.0M0.14%00.0%Unchanged
Price T Rowe Associates Inc1,714,905$28.1M0.00%+17,592+1.0%Added
Morgan Stanley2,114,572$34.7M0.00%−181,850−7.9%Reduced
Credit Suisse AG2,463,975$40.4M0.03%+117,457+5.0%Added
Goldman Sachs Group Inc2,519,008$41.3M0.01%+2,240,800+805.4%Added
Bank of America Corp2,664,343$43.7M0.00%+2,636,728+9,548.2%Added
Eventide Asset Management, LLC2,819,135$46.2M0.59%−910,054−24.4%Reduced
Wellington Management Group LLP2,856,986$46.8M0.01%+2,257,851+376.9%Added
FMR LLC3,491,547$57.2M0.00%+12,618+0.4%Added
Perceptive Advisors LLC3,679,845$60.3M0.93%00.0%Unchanged
CoreCap Advisors, LLC18––+18New
Pictet Asset Management SA0$00.00%−1,767,508−100.0%Sold out
Lone Pine Capital LLCSuperinvestorLone Pine Capital0$00.00%−976,735−100.0%Sold out
Bailard, Inc.0$00.00%−73,200−100.0%Sold out
Alps Advisors Inc0$00.00%−56,851−100.0%Sold out
J. Goldman & Co LP0$00.00%−49,992−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−50,000−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−38,814−100.0%Sold out
Vident Investment Advisory, LLC0$00.00%−38,784−100.0%Sold out
Jump Financial, LLC0$00.00%−33,841−100.0%Sold out
Gyon Technologies Capital Management, LP0$00.00%−33,737−100.0%Sold out
K.J. Harrison & Partners Inc0$00.00%−30,000−100.0%Sold out
Guggenheim Capital LLC0$00.00%−21,133−100.0%Sold out
Two Sigma Investments, LP0$00.00%−18,532−100.0%Sold out
Winton Group Ltd0$00.00%−17,977−100.0%Sold out
Silphium Asset Management Ltd0$00.00%−15,000−100.0%Sold out
ACT Capital Management, LLC0$00.00%−14,000−100.0%Sold out
Bank of New York Mellon Corp0$00.00%−13,894−100.0%Sold out
Vigilare Wealth Management0$00.00%−10,200−100.0%Sold out
Arizona State Retirement System0$00.00%−10,060−100.0%Sold out
Invesco Ltd.0$00.00%−9,871−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−9,490−100.0%Sold out
Caption Management, LLC0$00.00%−8,200−100.0%Sold out
1623 Capital LLC0$00.00%−7,724−100.0%Sold out
Values First Advisors, Inc.0$00.00%−7,072−100.0%Sold out
SG3 Management, LLC0$00.00%−6,100−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,306−100.0%Sold out
Captrust Financial Advisors0$00.00%−500−100.0%Sold out
Northwestern Mutual Wealth Management Co0$00.00%−200−100.0%Sold out
Consolidated Planning Corp0$00.00%−61−100.0%Sold out
Marshall Wace North America L.P.––––Not filed
Knott David M––––Not filed