Skip to main content

Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Trust Co of the South934$417.1K0.07%+100+12.0%Added
Turtle Creek Wealth Advisors, LLC938$418.9K0.03%+215+29.7%Added
Persistent Asset Partners Ltd939$419.3K0.16%−1,727−64.8%Reduced
VARCOV Co.941$420.2K0.16%+941New
Transamerica Financial Advisors, Inc.941$420.5K0.04%−6,643−87.6%Reduced
Keel Point, LLC947$422.7K0.03%−269−22.1%Reduced
Goelzer Investment Management, Inc.947$422.9K0.02%−923−49.4%Reduced
Rathbone Brothers plc955$426.4K0.00%−289−23.2%Reduced
HighPoint Advisor Group LLC955$426.5K0.02%−5,134−84.3%Reduced
Moss Adams Wealth Advisors LLC957$427.5K0.03%+109+12.9%Added
Soltis Investment Advisors LLC959$428.1K0.03%+85+9.7%Added
Larry Mathis Financial Planning, LLC962$429.6K0.39%−731−43.2%Reduced
Catalyst Funds Management Pty Ltd965$430.9K0.07%+405+72.3%Added
Towarzystwo Funduszy Inwestycyjnych Pzu SA966$431.4K0.14%−223−18.8%Reduced
Ramiah Investment Group969$432.7K0.38%−75−7.2%Reduced
Optimize Financial Inc970$433.1K0.21%−114−10.5%Reduced
Defined Wealth Management, LLC979$437.2K0.26%+5+0.5%Added
Alta Advisers Ltd991$442.5K0.16%00.0%Unchanged
Urban Wealth Management, LLC991$442.5K0.45%+365+58.3%Added
Interchange Capital Partners, LLC919$442.6K0.14%+299+48.2%Added
Quotient Wealth Partners, LLC995$444.2K0.01%+81+8.9%Added
Moneta Group Investment Advisors LLC996$444.8K0.00%−111−10.0%Reduced
Washington Growth Strategies LLC998$445.6K0.29%00.0%Unchanged
Schwartz Investment Counsel Inc1,000$446.5K0.02%00.0%Unchanged
Retirement Planning Group1,003$447.8K0.01%+533+113.4%Added
Klingenstein Fields & Co LP1,005$448.8K0.02%00.0%Unchanged
Caitong International Asset Management Co., Ltd1,014$452.8K0.08%+1,014New
17 Capital Partners, LLC1,015$453.2K0.23%+25+2.5%Added
SageView Advisory Group, LLC1,017$454.1K0.02%−285−21.9%Reduced
Diametric Capital, LP1,020$455.5K0.12%+1,020New
Catalytic Wealth RIA, LLC1,022$456.4K0.02%−200−16.4%Reduced
Sunbelt Securities, Inc.1,022$456.4K0.03%−4−0.4%Reduced
NorthCrest Asset Manangement, LLC1,056$463.2K0.01%−39−3.6%Reduced
AGH Wealth Advisors, LLC1,046$467.1K0.34%+40+4.0%Added
Dynasty Wealth Management, LLC1,049$468.4K0.00%+36+3.6%Added
Ancora Advisors, LLC1,050$469.0K0.01%+151+16.8%Added
Guardian Wealth Advisors, LLC1,053$470.0K0.03%00.0%Unchanged
Sigma Planning Corp1,062$474.2K0.01%−624−37.0%Reduced
Investment Management Corp1,064$475.0K0.41%+21+2.0%Added
Founders Financial Alliance, LLC1,064$475.1K0.09%−37−3.4%Reduced
Versant Capital Management, Inc1,066$476.0K0.05%+370+53.2%Added
TownSquare Capital, LLC1,071$478.2K0.11%+64+6.4%Added
Renaissance Group LLC1,072$478.9K0.02%−361−25.2%Reduced
Paladin Wealth, LLC1,074$479.6K0.33%−101−8.6%Reduced
NorthRock Partners, LLC1,079$482.3K0.01%−6−0.6%Reduced
LVW Advisors, LLC1,088$485.8K0.05%−386−26.2%Reduced
Invesco, LLC1,091$487.2K0.17%00.0%Unchanged
First Citizens Bank & Trust Co1,092$487.6K0.01%+182+20.0%Added
Jacobi Capital Management LLC1,094$488.5K0.03%+33+3.1%Added
Fairfield Financial Advisors, LTD1,098$490.3K0.17%00.0%Unchanged
Churchill Financial Advisors, LLC1,100$491.2K0.10%−150−12.0%Reduced
BOK Financial Private Wealth, Inc.1,103$492.5K0.03%−159−12.6%Reduced
Sage Capital Advisors,llc1,112$496.4K0.12%+8+0.7%Added
Boston Family Office LLC1,116$498.0K0.03%+370+49.6%Added
Meadowbrook Advisors Group, LLC1,118$499.2K0.30%−33−2.9%Reduced
Davis R M Inc1,121$500.6K0.01%−14−1.2%Reduced
Bridgewater Advisors Inc.1,109$502.6K0.03%+33+3.1%Added
CWA Asset Management Group, LLC1,126$502.8K0.02%−2,663−70.3%Reduced
First Commonwealth Financial Corp1,135$506.6K0.08%+1+0.1%Added
Williams Jones Wealth Management, LLC.1,135$506.8K0.01%−20−1.7%Reduced
Second Line Capital, LLC1,189$508.2K0.10%+45+3.9%Added
Advisors Capital Management, LLC1,138$508.6K0.01%−514−31.1%Reduced
Chicago Partners Investment Group LLC1,170$512.1K0.01%+303+34.9%Added
PUREfi Wealth, LLC1,153$514.9K0.34%+336+41.1%Added
LCM Capital Management Inc1,158$517.1K0.26%+23+2.0%Added
Optas, LLC1,160$518.0K0.08%+125+12.1%Added
Foundations Investment Advisors, LLC1,164$519.7K0.01%+317+37.4%Added
Redhawk Wealth Advisors, Inc.1,164$519.8K0.06%+8+0.7%Added
Conning Inc.1,167$521.1K0.02%−233−16.6%Reduced
Independent Financial Group, LLC1,172$523.3K0.01%+103+9.6%Added
Accurate Wealth Management, LLC1,202$524.6K0.06%−60−4.8%Reduced
Park National Corp1,180$526.9K0.02%+1,180New
Total Clarity Wealth Management, Inc.1,183$528.3K0.12%00.0%Unchanged
Weatherly Asset Management L. P.1,184$528.7K0.04%00.0%Unchanged
Portfolio Design Labs, LLC1,191$531.8K0.09%−14−1.2%Reduced
GeoWealth Management, LLC1,207$539.2K0.02%+197+19.5%Added
KCM Investment Advisors LLC1,213$541.7K0.02%+237+24.3%Added
Abc Arbitrage SA1,215$542.5K0.07%+1,215New
Ameritas Advisory Services, LLC1,216$543.0K0.02%−626−34.0%Reduced
St. Louis Trust Co1,218$543.9K0.06%00.0%Unchanged
Keynote Financial Services LLC1,231$549.7K0.29%+65+5.6%Added
BridgePort Financial Solutions, LLC1,233$550.6K0.16%+24+2.0%Added
SBI Securities Co., Ltd.1,237$552.4K0.02%−82−6.2%Reduced
Merrion Investment Management Co, LLC1,250$558.2K0.30%00.0%Unchanged
TIAA Wealth Investment Management LLC1,257$561.3K0.00%+1,257New
Tobam1,259$562.0K0.15%+105+9.1%Added
Resurgent Financial Advisors LLC1,260$562.6K0.21%+111+9.7%Added
Natural Investments, LLC1,265$565.0K0.14%+92+7.8%Added
West Family Investments, Inc.1,274$568.9K0.20%−1,054−45.3%Reduced
Wakefield Asset Management LLLP1,276$569.8K0.15%00.0%Unchanged
Green Harvest Asset Management LLC1,280$571.6K0.01%+34+2.7%Added
Paces Ferry Wealth Advisors, LLC1,286$574.3K0.24%00.0%Unchanged
Hancock Whitney Corp1,341$574.5K0.01%+15+1.1%Added
Regions Financial Corp1,300$580.5K0.00%+191+17.2%Added
Capital Investment Advisors, LLC1,303$581.8K0.01%+132+11.3%Added
BIP Wealth, LLC1,307$583.6K0.02%+92+7.6%Added
DGS Capital Management, LLC1,310$585.0K0.10%+149+12.8%Added
First Affirmative Financial Network1,314$586.6K0.23%+1,314New
Larson Financial Group LLC1,319$589.0K0.02%+232+21.3%Added
Boothbay Fund Management, LLC1,320$589.4K0.01%+1,320New