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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
F/M Investments LLC29,298$13.0M0.47%+50.0%Added
Washington Trust Bank29,243$13.0M1.10%+943+3.3%Added
Citadel Advisors LLC28,827$12.8M0.01%+23,808+474.4%Added
OP Asset Management Ltd27,777$12.4M0.18%+347+1.3%Added
Shelter Mutual Insurance Co27,600$12.3M2.85%00.0%Unchanged
Capital Group Investment Management Pte. Ltd.27,499$12.2M2.18%+3,647+15.3%Added
Profund Advisors LLC27,353$12.2M0.44%+2,682+10.9%Added
Foster Victor Wealth Advisors, LLC25,364$12.1M0.82%+2,440+10.6%Added
Liontrust Investment Partners LLP26,954$12.0M0.17%+12,911+91.9%Added
Massmutual Trust Co FSB26,791$11.9M0.32%+9,775+57.4%Added
Bender Robert & Associates26,712$11.9M2.65%−313−1.2%Reduced
ASR Vermogensbeheer N.V.26,419$11.8M0.15%−103−0.4%Reduced
Fagan Associates, Inc.26,195$11.7M1.80%−90−0.3%Reduced
Yousif Capital Management, LLC26,117$11.6M0.13%−304−1.2%Reduced
Blair William & Co26,077$11.6M0.03%−768−2.9%Reduced
Fisher Asset Management, LLC25,755$11.5M0.00%−4,914−16.0%Reduced
Avanza Fonder AB25,425$11.3M0.34%+1,405+5.8%Added
Bogart Wealth, LLC25,407$11.3M0.48%+6,240+32.6%Added
Wiley Bros.-Aintree Capital, LLC25,140$11.2M0.09%+11,187+80.2%Added
Pinnacle Associates Ltd25,108$11.2M0.16%+210+0.8%Added
Advisors Asset Management, Inc.25,085$11.2M0.20%−2,659−9.6%Reduced
Dai-Ichi Life Insurance Company, Ltd25,036$11.1M0.31%−5,965−19.2%Reduced
Biondo Investment Advisors, LLC24,929$11.1M1.46%−220−0.9%Reduced
Nordea Investment Management AB24,512$10.9M0.01%+1,057+4.5%Added
HealthInvest Partners AB24,328$10.8M4.64%+1,520+6.7%Added
Fifth Third Bancorp24,224$10.8M0.04%−1,585−6.1%Reduced
ARK Investment Management LLCSuperinvestorARK Invest24,063$10.7M0.08%−2,281−8.7%Reduced
Allianz SE23,935$10.7M0.25%−12−0.1%Reduced
Cary Street Partners Financial LLC23,509$10.5M0.29%−197−0.8%Reduced
Atria Investments LLC23,501$10.5M0.12%+219+0.9%Added
Tower Research Capital LLC (TRC)23,478$10.5M0.28%+10,362+79.0%Added
Verition Fund Management LLC23,242$10.3M0.06%+9,990+75.4%Added
Somerville Kurt F23,186$10.3M1.74%+310+1.4%Added
Modera Wealth Management, LLC23,105$10.3M0.13%−868−3.6%Reduced
Galvin, Gaustad & Stein, LLC22,890$10.2M0.88%+1,529+7.2%Added
GW Henssler & Associates Ltd22,763$10.1M0.54%−48−0.2%Reduced
EULAV Asset Management22,700$10.1M0.24%−5,800−20.4%Reduced
William Blair Investment Management, LLC22,608$10.1M0.03%−56,724−71.5%Reduced
Steel Peak Wealth Management LLC22,594$10.1M0.39%+22,594New
Oregon Public Employees Retirement Fund22,184$9.88M0.17%+100+0.5%Added
Churchill Management Corp21,996$9.79M0.11%−4,392−16.6%Reduced
Norinchukin Bank, The21,936$9.77M0.15%+1,859+9.3%Added
Oppenheimer Asset Management Inc.21,488$9.57M0.11%−206−0.9%Reduced
Gotham Asset Management, LLC21,356$9.51M0.06%−6,421−23.1%Reduced
FIL Ltd21,114$9.40M0.01%−72,294−77.4%Reduced
Azimuth Capital Investment Management LLC21,032$9.36M0.35%−211−1.0%Reduced
AIMZ Investment Advisors, LLC20,726$9.23M3.09%−225−1.1%Reduced
Camden National Bank20,462$9.11M1.31%−204−1.0%Reduced
Sterling Capital Management LLC20,444$9.10M0.13%+8,070+65.2%Added
Warren Averett Asset Management, LLC20,145$8.97M0.10%+309+1.6%Added
D. E. Shaw & Co., Inc.20,081$8.94M0.01%−51,852−72.1%Reduced
Freemont Management S.A.20,000$8.90M1.47%+14,200+244.8%Added
First Horizon Advisors, Inc.19,719$8.78M0.23%+404+2.1%Added
Public Sector Pension Investment Board19,674$8.76M0.04%−15,435−44.0%Reduced
Anderson Hoagland & Co19,647$8.75M0.83%−176−0.9%Reduced
Heirloom Wealth Management19,633$8.74M2.31%+80+0.4%Added
Prudential PLC19,525$8.69M0.05%−542−2.7%Reduced
Kennedy Capital Management, Inc.19,410$8.64M0.21%−1,047−5.1%Reduced
Telos Capital Management, Inc.19,242$8.57M0.87%+1,068+5.9%Added
QRG Capital Management, Inc.19,036$8.47M0.07%+1,643+9.4%Added
Bridger Management, LLC18,778$8.36M4.93%−22,272−54.3%Reduced
Mercer Global Advisors Inc18,523$8.25M0.02%+3,462+23.0%Added
Vident Advisory, LLC18,500$8.24M0.09%+2,422+15.1%Added
Grandfield & Dodd, LLC18,287$8.14M0.48%+141+0.8%Added
Quadrature Capital Ltd17,913$7.97M0.14%+17,913New
Mizuho Securities USA LLC17,750$7.90M0.17%+17,750New
M&T Bank Corp17,683$7.87M0.03%−681−3.7%Reduced
Broderick Brian C17,671$7.87M1.56%−330−1.8%Reduced
Fiduciary Trust Co17,519$7.80M0.10%+255+1.5%Added
Intech Investment Management LLC17,488$7.79M0.07%+8,791+101.1%Added
Wolverine Trading, LLC17,595$7.76M0.20%+16,180+1,143.5%Added
Cambridge Investment Research Advisors, Inc.17,329$7.71M0.02%+998+6.1%Added
Envestnet Portfolio Solutions, Inc.17,294$7.70M0.03%+272+1.6%Added
Shell Asset Management Co17,181$7.65M0.26%+3,809+28.5%Added
Silvercrest Asset Management Group LLC16,953$7.55M0.05%+107+0.6%Added
Banque Pictet & Cie SA16,937$7.54M0.08%+5,564+48.9%Added
Agf Management Ltd16,885$7.52M0.03%+5,402+47.0%Added
Torray LLC16,879$7.51M1.09%+1,158+7.4%Added
Callan Family Office, LLC16,715$7.44M0.23%+11,198+203.0%Added
UniSuper Management Pty Ltd16,648$7.41M0.05%−189−1.1%Reduced
Generali Asset Management SPA SGR16,627$7.40M0.17%−1,705−9.3%Reduced
Kentucky Retirement Systems16,574$7.38M0.22%−1,085−6.1%Reduced
Baird Financial Group, Inc.16,392$7.30M0.01%+391+2.4%Added
Gabelli Funds LLC16,329$7.27M0.05%−21−0.1%Reduced
Janney Capital Management LLC16,231$7.23M0.47%−276−1.7%Reduced
Ieq Capital, LLC16,219$7.22M0.04%−5,786−26.3%Reduced
Beacon Pointe Advisors, LLC16,029$7.14M0.07%−196−1.2%Reduced
NBW Capital LLC15,939$7.10M1.53%+293+1.9%Added
Nia Impact Advisors, LLC15,887$7.07M2.44%−45−0.3%Reduced
Fulcrum Capital LLC15,798$7.03M1.49%+220+1.4%Added
Motley Fool Asset Management LLC15,794$7.03M0.32%+1,875+13.5%Added
New Age Alpha Advisors, LLC15,700$6.99M0.31%+2,563+19.5%Added
South Dakota Investment Council15,623$6.96M0.13%−10,780−40.8%Reduced
Hartford Investment Management Co15,498$6.90M0.22%−172−1.1%Reduced
Park Avenue Securities LLC15,362$6.84M0.06%+23+0.1%Added
Puzo Michael J15,340$6.83M1.95%+55+0.4%Added
Trifecta Capital Advisors, LLC15,340$6.83M1.14%+802+5.5%Added
Northwest & Ethical Investments L.P.15,089$6.72M0.17%+530+3.6%Added
Princeton Global Asset Management LLC15,025$6.69M1.21%−186−1.2%Reduced
Ameritas Investment Partners, Inc.14,909$6.64M0.21%−1,110−6.9%Reduced