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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
GF Fund Management Co. Ltd.62,317$27.7M0.56%+1,505+2.5%Added
Susquehanna International Group, LLP62,209$27.7M0.04%+21,088+51.3%Added
Trillium Asset Management, LLC61,474$27.4M0.74%+5,658+10.1%Added
Arrowstreet Capital, Limited Partnership61,470$27.4M0.02%+61,470New
Rhenman & Partners Asset Management AB61,455$27.4M3.46%−5,295−7.9%Reduced
Epoch Investment Partners, Inc.61,026$27.2M0.14%−20,810−25.4%Reduced
Foster Dykema Cabot & Partners, LLC60,923$27.1M1.91%−532−0.9%Reduced
Groupama Asset Managment61,297$27.1M0.45%+9,364+18.0%Added
Cetera Investment Advisers60,196$26.8M0.05%−4,578−7.1%Reduced
Commonwealth Equity Services, LLC59,398$26.4M0.03%−6,346−9.7%Reduced
Moody Lynn & Lieberson, LLC58,077$25.9M1.49%+822+1.4%Added
Swiss Life Asset Management Ltd57,900$25.8M0.15%+28,296+95.6%Added
HighTower Advisors, LLC56,347$25.1M0.03%+2,722+5.1%Added
Edgemoor Investment Advisors, Inc.56,024$24.9M2.15%−772−1.4%Reduced
Amalgamated Bank55,735$24.8M0.19%+2,005+3.7%Added
Hemenway Trust Co LLC55,515$24.7M1.91%+1,191+2.2%Added
Atwood & Palmer Inc55,192$24.6M1.54%+208+0.4%Added
Retirement Systems of Alabama55,102$24.5M0.09%−80−0.1%Reduced
Zacks Investment Management54,316$24.2M0.21%−31,734−36.9%Reduced
Reynders McVeigh Capital Management, LLC54,310$24.2M1.21%+974+1.8%Added
MEAG MUNICH ERGO, Kapitalanlagegesellschaft mbH54,104$24.1M0.68%+54,104New
Motley Fool Wealth Management, LLC53,913$24.0M1.45%+20,864+63.1%Added
Illinois Municipal Retirement Fund53,624$23.9M0.32%+3,034+6.0%Added
Shelton Capital Management53,015$23.6M0.54%−336−0.6%Reduced
Zurich Insurance Group Ltd52,372$23.3M0.18%−157,534−75.0%Reduced
Barlow Wealth Partners, Inc.50,958$23.3M2.79%+865+1.7%Added
Cullinan Associates Inc52,012$23.2M1.53%−1,100−2.1%Reduced
Forsta Ap-Fonden52,000$23.2M0.15%−6,200−10.7%Reduced
Advisor Group Holdings, Inc.50,328$22.9M0.04%+16,779+50.0%Added
AustralianSuper Pty Ltd51,256$22.8M0.12%−76,687−59.9%Reduced
Jacobs Levy Equity Management, Inc50,956$22.7M0.09%−15,278−23.1%Reduced
CIBC World Markets Corp50,606$22.5M0.15%+19,599+63.2%Added
IFM Investors Pty Ltd50,317$22.4M0.21%+1,781+3.7%Added
Hudson Bay Capital Management LP50,246$22.4M0.15%+405+0.8%Added
Harvest Fund Management Co., Ltd49,515$22.1M1.04%+14,580+41.7%Added
Bank of Nova Scotia49,609$22.1M0.05%+21,921+79.2%Added
De Burlo Group Inc48,765$21.7M2.86%+30+0.1%Added
Hallmark Capital Management Inc48,689$21.7M1.56%−795−1.6%Reduced
Sumitomo Mitsui DS Asset Management Company, Ltd48,090$21.4M0.19%+1,726+3.7%Added
Sanctuary Advisors, LLC47,170$21.0M0.13%+1,303+2.8%Added
Cumberland Partners Ltd46,570$20.7M1.44%−177−0.4%Reduced
Quantinno Capital Management LP46,322$20.6M0.09%+7,897+20.6%Added
Smith Group Asset Management, LLC46,255$20.6M1.35%+612+1.3%Added
Boston Common Asset Management, LLC46,063$20.5M0.57%−4,900−9.6%Reduced
C WorldWide Group Holding A/S46,057$20.5M0.28%−8,000−14.8%Reduced
Lido Advisors, LLC45,822$20.4M0.11%+11,590+33.9%Added
Calamos Advisors LLC45,753$20.4M0.09%00.0%Unchanged
Aristotle Atlantic Partners, LLC45,376$20.2M0.61%−2,610−5.4%Reduced
State of Alaska, Department of Revenue45,255$20.1M0.22%−1,250−2.7%Reduced
Ilmarinen Mutual Pension Insurance Co44,800$19.9M0.16%+11,500+34.5%Added
AIA Group Ltd44,484$19.8M0.43%+10,255+30.0%Added
China Universal Asset Management Co., Ltd.44,265$19.7M1.85%−4,601−9.4%Reduced
USS Investment Management Ltd44,154$19.7M0.12%−237−0.5%Reduced
Wealthfront Advisers LLC43,918$19.6M0.05%−3,014−6.4%Reduced
W.G. Shaheen & Associates DBA Whitney & Co43,809$19.5M1.92%+140.0%Added
Utah Retirement Systems42,533$18.9M0.20%−270−0.6%Reduced
Segall Bryant & Hamill, LLC42,328$18.8M0.26%−10,494−19.9%Reduced
Steward Partners Investment Advisory, LLC41,551$18.5M0.14%+518+1.3%Added
Martingale Asset Management L P41,282$18.4M0.45%−565−1.4%Reduced
Pacer Advisors, Inc.39,958$17.8M0.04%+9,262+30.2%Added
La Banque Postale Asset Management SA39,341$17.5M0.25%−14,200−26.5%Reduced
Burney Co39,131$17.4M0.59%+326+0.8%Added
Police & Firemen's Retirement System of New Jersey39,035$17.4M0.16%+1,393+3.7%Added
Congress Wealth Management LLC38,915$17.3M0.17%+4,801+14.1%Added
New York Life Investment Management LLC38,900$17.3M0.16%+294+0.8%Added
JustInvest LLC38,491$17.1M0.19%+2,729+7.6%Added
Bailard, Inc.38,147$17.0M0.40%+200+0.5%Added
Gradient Investments LLC38,013$16.9M0.31%+38,013New
Flputnam Investment Management Co37,741$16.8M0.29%+1,245+3.4%Added
Tweedy, Browne Co LLC37,253$16.6M1.54%−1,063−2.8%Reduced
Varma Mutual Pension Insurance Co36,626$16.3M0.12%−1,000−2.7%Reduced
MML Investors Services, LLC36,607$16.3M0.05%−4,448−10.8%Reduced
Cornerstone Advisors, LLC36,600$16.3M0.56%+23,600+181.5%Added
Pathstone Holdings, LLC36,433$16.2M0.06%−1,441−3.8%Reduced
Sapient Capital LLC36,310$16.2M0.29%+314+0.9%Added
Mackenzie Financial Corp36,275$16.1M0.02%+209+0.6%Added
iA Global Asset Management Inc.35,157$15.7M0.24%−167−0.5%Reduced
Adams Diversified Equity Fund, Inc.35,100$15.6M0.56%00.0%Unchanged
Jefferies Financial Group Inc.34,615$15.4M0.25%+15,131+77.7%Added
Bridgewater Associates, LP34,390$15.3M0.06%+34,390New
O'Shaughnessy Asset Management, LLC34,259$15.3M0.10%−1,341−3.8%Reduced
US Bancorp33,583$15.0M0.02%+1,324+4.1%Added
Huntington National Bank33,412$14.9M0.10%−2,356−6.6%Reduced
Elo Mutual Pension Insurance Co33,292$14.8M0.30%+161+0.5%Added
Los Angeles Capital Management LLC33,014$14.7M0.06%+7,291+28.3%Added
Meritage Portfolio Management32,943$14.7M0.93%−1,934−5.5%Reduced
Citizens Financial Group Inc32,918$14.7M0.24%+10,108+44.3%Added
Sig Brokerage, LP32,566$14.5M3.98%+31,446+2,807.7%Added
Louisiana State Employees Retirement System32,300$14.4M0.26%−300−0.9%Reduced
Kovitz Investment Group Partners, LLC32,043$14.3M0.06%+23,574+278.4%Added
Atalanta Sosnoff Capital, LLC31,756$14.1M0.29%−11,939−27.3%Reduced
Vestcor Inc31,488$14.0M0.42%−653−2.0%Reduced
Natixis30,961$13.8M0.07%−24,473−44.1%Reduced
CIBC World Markets Inc.30,794$13.7M0.03%+16,309+112.6%Added
PEAK6 LLC30,456$13.6M0.46%+14,990+96.9%Added
McRae Capital Management Inc30,453$13.6M2.78%+125+0.4%Added
LVM Capital Management Ltd30,070$13.4M1.39%+157+0.5%Added
Apollon Wealth Management, LLC29,757$13.2M0.26%+4,630+18.4%Added
CCM Investment Advisers LLC29,615$13.2M1.42%+2,062+7.5%Added
Mutual of America Capital Management LLC29,406$13.1M0.14%−2,069−6.6%Reduced