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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Baldwin Investment Management, LLC14,541$6.47M0.78%+711+5.1%Added
Princeton Capital Management LLC14,475$6.44M1.91%−561−3.7%Reduced
Sequoia Financial Advisors, LLC14,373$6.40M0.04%+442+3.2%Added
Kestra Advisory Services, LLC14,358$6.39M0.03%+1,148+8.7%Added
TD Waterhouse Canada Inc.14,102$6.37M0.05%+4,479+46.5%Added
Toroso Investments, LLC14,265$6.35M0.04%−126−0.9%Reduced
Madison Asset Management, LLC14,192$6.32M0.07%−204−1.4%Reduced
Metis Global Partners, LLC14,118$6.29M0.16%−1,581−10.1%Reduced
Knuff & Co LLC13,996$6.23M1.96%+171+1.2%Added
Bleakley Financial Group, LLC13,931$6.20M0.16%+2,609+23.0%Added
Aptus Capital Advisors, LLC13,887$6.18M0.06%−10,353−42.7%Reduced
Channel Wealth LLC13,877$6.18M1.75%+11,833+578.9%Added
Omers Administration Corp13,754$6.12M0.05%+100+0.7%Added
BI Asset Management Fondsmaeglerselskab A/S13,677$6.09M0.06%+1,949+16.6%Added
PKO Investment Management Joint-Stock Co13,500$6.01M0.65%+11,700+650.0%Added
Securian Asset Management, Inc13,442$5.98M0.17%−156−1.1%Reduced
Captrust Financial Advisors13,312$5.93M0.01%−218−1.6%Reduced
Jump Financial, LLC13,292$5.92M0.07%+12,084+1,000.3%Added
Gulf International Bank (UK) Ltd13,134$5.85M0.21%−1,774−11.9%Reduced
Ci Investments Inc.13,128$5.84M0.02%−17,886−57.7%Reduced
United Capital Financial Advisers, LLC13,122$5.84M0.05%+1,156+9.7%Added
Fisher Funds Management LTD12,898$5.74M0.14%−1,433−10.0%Reduced
Chicago Capital, LLC12,875$5.73M0.14%+469+3.8%Added
Avantax Advisory Services, Inc.12,873$5.73M0.03%+199+1.6%Added
Forte Capital LLC12,587$5.60M0.60%+135+1.1%Added
Compagnie Lombard Odier SCmA12,565$5.59M0.07%00.0%Unchanged
Maryland State Retirement & Pension System12,500$5.57M0.12%+409+3.4%Added
Oddo BHF Asset Management SAS12,388$5.52M0.21%−4,309−25.8%Reduced
Americana Partners, LLC12,334$5.49M0.19%+97+0.8%Added
Cresset Asset Management, LLC12,227$5.44M0.03%−2,100−14.7%Reduced
Covenant Asset Management, LLC12,155$5.41M1.11%−387−3.1%Reduced
Kidder Stephen W12,130$5.40M1.62%+164+1.4%Added
Kayne Anderson Rudnick Investment Management LLC12,013$5.35M0.01%−221−1.8%Reduced
New Mexico Educational Retirement Board12,000$5.34M0.17%00.0%Unchanged
GWM Advisors LLC11,929$5.31M0.03%+986+9.0%Added
BTC Capital Management, Inc.11,928$5.31M0.43%+589+5.2%Added
Traynor Capital Management, Inc.11,675$5.28M0.37%+631+5.7%Added
Slow Capital, Inc.11,814$5.26M0.64%−20−0.2%Reduced
Codex Capital Asset Management L.L.C.11,750$5.23M2.09%00.0%Unchanged
Investment Management Corp of Ontario11,675$5.20M0.08%−3,092−20.9%Reduced
Northwestern Mutual Wealth Management Co11,532$5.13M0.00%−1,505−11.5%Reduced
Ethic Inc.11,495$5.07M0.09%+58+0.5%Added
First American Trust, FSB11,348$5.05M0.40%−5,663−33.3%Reduced
Brinker Capital Investments, LLC11,341$5.05M0.04%+1,768+18.5%Added
Diversify Wealth Management, LLC12,988$5.04M0.31%+1,976+17.9%Added
EFG Asset Management (North America) Corp.11,204$4.99M0.70%+2,072+22.7%Added
Northwest Bancshares, Inc.11,203$4.99M0.87%−216−1.9%Reduced
Spire Wealth Management11,298$4.91M0.18%−7,278−39.2%Reduced
EP Wealth Advisors, LLC10,930$4.87M0.03%+5,481+100.6%Added
Siemens Fonds Invest GmbH10,915$4.86M0.29%+307+2.9%Added
Lockheed Martin Investment Management Co10,860$4.83M0.18%+2,760+34.1%Added
Mark Sheptoff Financial Planning, LLC10,771$4.80M2.56%+100+0.9%Added
Keybank National Association10,678$4.75M0.02%−1,523−12.5%Reduced
Thematics Asset Management10,598$4.72M0.21%+2,642+33.2%Added
HB Wealth Management, LLC10,583$4.71M0.04%−73−0.7%Reduced
GAM Holding AG10,553$4.70M0.33%−492−4.5%Reduced
Banque Cantonale Vaudoise10,529$4.69M0.19%+231+2.2%Added
E. Ohman J:or Asset Management AB10,520$4.68M0.12%−970−8.4%Reduced
Generali Investments CEE, investicni spolecnost, a.s.10,491$4.67M0.38%−539−4.9%Reduced
Parsons Capital Management Inc10,428$4.64M0.29%+2,660+34.2%Added
Fayez Sarofim & Co10,358$4.61M0.01%−34−0.3%Reduced
Greenwood Capital Associates LLC10,298$4.58M0.57%−1,595−13.4%Reduced
Morse Asset Management, Inc10,287$4.58M1.00%−174−1.7%Reduced
Vinva Investment Management Ltd10,345$4.57M0.12%−2,792−21.3%Reduced
Prospera Financial Services Inc10,235$4.56M0.08%+7,204+237.7%Added
Crestwood Advisors Group LLC10,043$4.47M0.08%−232−2.3%Reduced
Tang Capital Management LLC10,000$4.45M0.23%+10,000New
Diadema Partners LP10,000$4.45M2.77%+10,000New
Commerzbank Aktiengesellschaft9,850$4.39M0.10%+8,069+453.1%Added
Empowered Funds, LLC9,822$4.37M0.05%+4,632+89.2%Added
AG2R la Mondiale Gestion D'Actifs9,788$4.36M0.22%+187+1.9%Added
Synovus Financial Corp9,777$4.35M0.05%+1,271+14.9%Added
Baker Chad R9,740$4.34M0.81%00.0%Unchanged
Benjamin Edwards Inc9,634$4.29M0.05%+1,428+17.4%Added
Meiji Yasuda Asset Management Co Ltd.9,633$4.29M0.21%−3,013−23.8%Reduced
E Fund Management Co., Ltd.9,628$4.29M0.20%−256−2.6%Reduced
Pinnacle Financial Partners Inc9,617$4.28M0.09%+263+2.8%Added
Hamilton Capital Partners Inc.9,516$4.24M0.22%+1,742+22.4%Added
Howe & Rusling Inc9,444$4.20M0.31%+318+3.5%Added
Sigma Investment Counselors Inc9,299$4.14M0.23%+548+6.3%Added
Bulltick Wealth Management, LLC9,095$4.05M1.00%+6+0.1%Added
Central Trust Co9,016$4.01M0.09%+31+0.3%Added
Empirical Finance, LLC9,006$4.01M0.21%+60+0.7%Added
Bamco Inc9,000$4.01M0.01%−3,000−25.0%Reduced
Atlantic Union Bankshares Corp8,947$3.98M0.09%+7,876+735.4%Added
Howard Capital Management Inc.8,918$3.97M0.06%+2,282+34.4%Added
Bensler, LLC8,795$3.92M0.44%−40−0.5%Reduced
Hedeker Wealth, LLC8,791$3.91M0.91%−216−2.4%Reduced
Vestmark Advisory Solutions, Inc.8,763$3.90M0.06%−3,625−29.3%Reduced
Tokio Marine Asset Management Co Ltd8,741$3.89M0.15%+536+6.5%Added
Ascent Group, LLC8,652$3.85M0.15%−790−8.4%Reduced
Privium Fund Management B.V.8,300$3.75M0.81%00.0%Unchanged
Sepio Capital, LP8,347$3.72M0.26%−13−0.2%Reduced
Bokf, NA8,254$3.67M0.06%+1,154+16.3%Added
Northwestern Mutual Investment Management Company, LLC8,193$3.65M0.06%+26+0.3%Added
Linden Thomas Advisory Services, LLC8,161$3.63M0.40%+428+5.5%Added
Peloton Wealth Strategists8,150$3.63M1.46%+196+2.5%Added
Leavell Investment Management, Inc.8,089$3.60M0.16%+355+4.6%Added
Tema ETFs LLC8,068$3.59M0.95%−380−4.5%Reduced
Federation des caisses Desjardins du Quebec8,038$3.58M0.02%−11,336−58.5%Reduced