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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Miracle Mile Advisors, LLC8,035$3.58M0.06%+1,467+22.3%Added
Andrew Hill Investment Advisors, Inc.8,003$3.56M2.87%+1,430+21.8%Added
Baldwin Brothers Inc7,994$3.56M0.24%−125−1.5%Reduced
Groupe la Francaise7,989$3.54M0.06%+1,625+25.5%Added
J.P. Marvel Investment Advisors, LLC7,855$3.50M0.56%−137−1.7%Reduced
Horizon Investments, LLC7,842$3.49M0.06%+2,793+55.3%Added
Joseph Group Capital Management7,760$3.45M1.16%+634+8.9%Added
Richard Bernstein Advisors LLC7,751$3.45M0.09%−855−9.9%Reduced
Johnson Investment Counsel Inc7,748$3.45M0.03%−171−2.2%Reduced
Duncker Streett & Co Inc7,732$3.44M0.63%−15−0.2%Reduced
Ashford Capital Management Inc7,707$3.43M0.40%−485−5.9%Reduced
Transamerica Financial Advisors, Inc.7,631$3.40M0.32%−220−2.8%Reduced
EagleClaw Capital Managment, LLC7,585$3.38M0.50%−10−0.1%Reduced
Associated Banc-Corp7,583$3.38M0.10%−580−7.1%Reduced
Paradigm Financial Partners, LLC7,562$3.37M0.37%−402−5.0%Reduced
Boston Private Wealth LLC7,507$3.34M0.18%−3,129−29.4%Reduced
Commerce Bank7,490$3.33M0.02%−853−10.2%Reduced
Bessemer Group Inc7,465$3.32M0.01%−19−0.3%Reduced
Level Four Advisory Services, LLC7,451$3.32M0.12%−985−11.7%Reduced
Cavalier Investments, LLC7,435$3.31M1.00%−138−1.8%Reduced
Notis-McConarty Edward7,381$3.29M1.60%+106+1.5%Added
Delaney Dennis R7,343$3.27M1.68%+440+6.4%Added
Sand Hill Global Advisors, LLC7,320$3.26M0.12%+395+5.7%Added
First National Bank of Mount Dora, Trust Investment Services7,291$3.25M0.73%−58−0.8%Reduced
GLOBALT Investments LLC7,285$3.24M0.12%−410−5.3%Reduced
Sumitomo Life Insurance Co7,236$3.22M0.22%−301−4.0%Reduced
Davidson Capital Management Inc.7,224$3.22M0.77%−196−2.6%Reduced
Private Advisor Group, LLC7,204$3.21M0.02%−248−3.3%Reduced
Dempze Nancy E7,180$3.20M1.84%+117+1.7%Added
Glenview Trust Co7,076$3.15M0.05%+156+2.3%Added
Kentucky Retirement Systems Insurance Trust Fund7,034$3.13M0.22%−488−6.5%Reduced
CIBC Private Wealth Group, LLC7,029$3.13M0.01%+467+7.1%Added
Sectoral Asset Management Inc6,945$3.09M2.04%+2,220+47.0%Added
CWM, LLC6,908$3.08M0.01%−776−10.1%Reduced
Kinneret Advisory, LLC6,895$3.07M0.28%−10−0.1%Reduced
North Star Asset Management Inc6,883$3.06M0.13%+864+14.4%Added
Vision Capital Management, Inc.6,872$3.06M0.40%+307+4.7%Added
Thompson Siegel & Walmsley LLC6,870$3.06M0.05%−239−3.4%Reduced
Brown Advisory Inc6,858$3.05M0.00%+277+4.2%Added
Graphene Investments SAS6,800$3.03M1.97%+1,300+23.6%Added
Hennion & Walsh Asset Management, Inc.6,756$3.01M0.12%−39−0.6%Reduced
Marex Group plc6,703$2.98M0.06%+6,703New
Coppell Advisory Solutions LLC6,686$2.95M0.36%+2,846+74.1%Added
Wedbush Securities Inc6,622$2.95M0.10%+19+0.3%Added
Principal Securities, Inc.6,600$2.94M0.06%+1,137+20.8%Added
Harbour Capital Advisors, LLC6,367$2.91M0.61%+145+2.3%Added
Nikko Asset Management Americas, Inc.6,527$2.90M0.03%−145−2.2%Reduced
Condor Capital Management6,502$2.89M0.25%−26−0.4%Reduced
Scotia Capital Inc.6,484$2.89M0.01%+412+6.8%Added
Draper Asset Management, LLC6,500$2.87M1.89%+69+1.1%Added
BLI - Banque de Luxembourg Investments6,500$2.87M0.08%+6,500New
NewEdge Wealth, LLC7,618$2.86M0.04%−1,690−18.2%Reduced
Edgestream Partners, L.P.6,415$2.86M0.08%+5,677+769.2%Added
Griffin Asset Management, Inc.6,408$2.85M0.34%−1,609−20.1%Reduced
RSM US Wealth Management LLC6,353$2.83M0.04%−40−0.6%Reduced
Diversify Advisory Services, LLC7,291$2.83M0.11%+1,518+26.3%Added
Advisory Services Network, LLC6,122$2.80M0.05%+409+7.2%Added
CWA Asset Management Group, LLC6,274$2.79M0.12%+69+1.1%Added
Merit Financial Group, LLC6,260$2.79M0.03%+833+15.3%Added
Crossmark Global Holdings, Inc.6,221$2.77M0.04%+47+0.8%Added
Meeder Advisory Services, Inc.6,176$2.75M0.14%−184−2.9%Reduced
Fred Alger Management, LLC6,173$2.75M0.01%−7,151−53.7%Reduced
Stonegate Investment Group, LLC6,142$2.73M0.07%−214−3.4%Reduced
Kestra Private Wealth Services, LLC6,127$2.73M0.04%+868+16.5%Added
B&L Asset Management LLC6,073$2.70M1.55%−75−1.2%Reduced
Northeast Financial Consultants Inc6,040$2.69M0.11%00.0%Unchanged
Broadleaf Partners, LLC6,018$2.68M0.59%+22+0.4%Added
Perigon Wealth Management, LLC6,004$2.67M0.06%+724+13.7%Added
Cohen Klingenstein LLC6,000$2.67M0.09%00.0%Unchanged
Te Ahumairangi Investment Management Ltd5,985$2.67M0.48%−3,133−34.4%Reduced
Highview Capital Management LLC5,985$2.66M1.03%+68+1.1%Added
Univest Financial Corp5,976$2.66M0.16%+2,086+53.6%Added
V-Square Quantitative Management LLC5,970$2.66M0.36%+1,875+45.8%Added
Jones Financial Companies LLLP6,016$2.66M0.00%+2,035+51.1%Added
Ostrum Asset Management5,894$2.62M0.12%−452−7.1%Reduced
Illumine Investment Management, LLC5,875$2.62M2.08%+21+0.4%Added
Coldstream Capital Management Inc5,874$2.62M0.04%+711+13.8%Added
Venturi Wealth Management, LLC5,871$2.61M0.13%−34−0.6%Reduced
Summit Trail Advisors, LLC5,871$2.61M0.04%+588+11.1%Added
Group One Trading, L.P.5,852$2.61M0.09%+5,852New
Segment Wealth Management, LLC5,843$2.60M0.17%+151+2.7%Added
Elefante Mark B5,832$2.60M1.95%+171+3.0%Added
Little House Capital LLC5,830$2.60M0.65%−477−7.6%Reduced
Plato Investment Management Ltd5,829$2.59M0.19%+4+0.1%Added
MASTERINVEST Kapitalanlage GmbH5,784$2.58M0.27%+5,784New
Nemes Rush Group LLC5,723$2.55M0.28%+977+20.6%Added
Freedom Day Solutions, LLC5,714$2.54M0.76%−127−2.2%Reduced
Mission Wealth Management, LP5,709$2.54M0.06%−1,202−17.4%Reduced
MUFG Securities Americas Inc.5,691$2.53M0.22%+1,146+25.2%Added
Wedmont Private Capital5,284$2.53M0.11%+929+21.3%Added
Qube Research & Technologies Ltd5,681$2.53M0.00%−28,865−83.6%Reduced
Wetherby Asset Management Inc5,672$2.53M0.11%+5,672New
Ipswich Investment Management Co., Inc.5,608$2.50M0.60%+90+1.6%Added
Alpine Woods Capital Investors, LLC5,594$2.49M0.59%+9+0.2%Added
Wimmer Associates 1, LLC5,592$2.49M1.27%−20.0%Reduced
BNP Paribas5,576$2.48M0.08%−258−4.4%Reduced
Hall Laurie J Trustee5,565$2.48M0.82%+37+0.7%Added
Central Pacific Bank - Trust Division5,559$2.47M0.32%+134+2.5%Added
Mediolanum International Funds Ltd5,494$2.42M0.03%+66+1.2%Added
Ballentine Partners, LLC5,428$2.42M0.04%−409−7.0%Reduced