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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Personal Cfo Solutions, LLC1,137$506.2K0.09%−22−1.9%Reduced
Orrstown Financial Services Inc1,137$506.2K0.11%+160+16.4%Added
Davis R M Inc1,135$505.1K0.01%+4+0.4%Added
Williams Jones Wealth Management, LLC.1,134$504.9K0.01%00.0%Unchanged
First Affirmative Financial Network1,133$504.2K0.26%+19+1.7%Added
David Loasby1,085$501.4K0.04%+148+15.8%Added
Accurate Wealth Management, LLC1,044$500.4K0.08%−385−26.9%Reduced
Gryphon Financial Partners LLC1,123$500.0K0.07%+5+0.4%Added
Albion Financial Group1,113$495.5K0.03%00.0%Unchanged
Blue Chip Partners, Inc.1,106$492.4K0.04%+265+31.5%Added
Invesco, LLC1,091$485.7K0.18%00.0%Unchanged
D.B. Root & Company, LLC1,082$481.7K0.14%−27−2.4%Reduced
Simplify Asset Management Inc.1,081$481.3K0.03%−114−9.5%Reduced
Quotient Wealth Partners, LLC1,071$476.8K0.01%−59−5.2%Reduced
Symphony Financial, Ltd. Co.2,353$475.9K0.06%+2,353New
Modern Wealth Management, LLC1,061$472.2K0.01%+115+12.2%Added
New England Research & Management, Inc.1,060$472.0K0.22%+1,060New
GPS Wealth Strategies Group, LLC1,059$471.5K0.05%−10−0.9%Reduced
Baker Ellis Asset Management LLC1,052$468.4K0.06%−221−17.4%Reduced
Interchange Capital Partners, LLC1,052$468.3K0.11%−36−3.3%Reduced
Guardian Wealth Advisors, LLC1,052$468.1K0.03%−24−2.2%Reduced
Parallax Volatility Advisers, L.P.1,046$465.7K0.02%+1,043+34,766.7%Added
J. Goldman & Co LP1,045$465.2K0.01%+1,045New
TFB Advisors LLC1,039$462.6K0.12%+16+1.6%Added
Richardson Financial Services Inc.1,020$461.2K0.31%+6+0.6%Added
SRS Capital Advisors, Inc.1,023$455.4K0.02%−5−0.5%Reduced
17 Capital Partners, LLC1,020$454.1K0.26%+20+2.0%Added
Natural Investments, LLC1,016$452.0K0.12%+199+24.4%Added
Investment Management Corp1,006$447.7K0.41%+14+1.4%Added
Klingenstein Fields & Co LP1,005$447.4K0.02%00.0%Unchanged
Foundations Investment Advisors, LLC1,002$446.1K0.01%+9+0.9%Added
Schwartz Investment Counsel Inc1,000$445.2K0.01%00.0%Unchanged
NJ State Employees Deferred Compensation Plan1,000$445.2K0.05%00.0%Unchanged
Legacy Capital Wealth Partners, LLC1,000$445.2K0.10%+50+5.3%Added
Capital Investment Advisors, LLC997$444.0K0.01%−35−3.4%Reduced
SK Wealth Management, LLC927$444.0K0.19%−530−36.4%Reduced
Washington Growth Strategies LLC998$444.0K0.34%+513+105.8%Added
Davis Investment Partners, LLC972$439.5K0.16%00.0%Unchanged
RiverFront Investment Group, LLC987$439.4K0.01%+375+61.3%Added
Jacobi Capital Management LLC986$439.0K0.03%+22+2.3%Added
Private Trust Co NA986$438.7K0.04%+21+2.2%Added
Atom Investors LP970$431.8K0.04%+970New
Investment House LLC969$431.4K0.02%−75−7.2%Reduced
Guardian Asset Advisors, LLC967$430.5K0.25%+67+7.4%Added
Virtus Investment Advisers, Inc.966$430.1K0.15%+193+25.0%Added
Koss-Olinger Consulting, LLC957$426.0K0.03%−41−4.1%Reduced
GeoWealth Management, LLC954$424.7K0.02%−89−8.5%Reduced
Kraematon Investment Advisors, Inc951$423.5K0.40%−4−0.4%Reduced
MQS Management LLC950$422.9K0.23%+950New
HMS Capital Management, LLC948$422.1K0.19%−122−11.4%Reduced
Dohj, LLC857$422.0K0.12%+857New
EverSource Wealth Advisors, LLC946$420.9K0.02%+380+67.1%Added
TRUE Private Wealth Advisors945$420.6K0.05%−1−0.1%Reduced
Sunbelt Securities, Inc.1,035$416.8K0.04%00.0%Unchanged
PUREfi Wealth, LLC936$416.7K0.33%+42+4.7%Added
J2 Capital Management Inc928$413.1K0.33%+250+36.9%Added
Cynosure Management, LLC918$408.7K0.05%+215+30.6%Added
Evoke Wealth, LLC916$407.8K0.01%−257−21.9%Reduced
Savvy Advisors, Inc.907$403.8K0.03%+285+45.8%Added
Optas, LLC907$403.8K0.08%−875−49.1%Reduced
Defined Wealth Management, LLC905$402.9K0.25%−17−1.8%Reduced
Granite Bay Wealth Management, LLC900$401.0K0.13%+300+50.0%Added
Cozad Asset Management Inc900$400.7K0.04%00.0%Unchanged
Two Sigma Advisers, LP900$400.7K0.00%+900New
Ramiah Investment Group893$397.6K0.43%−254−22.1%Reduced
YHB Investment Advisors, Inc.891$396.7K0.03%−50−5.3%Reduced
Arthur M. Cohen & Associates, LLC890$396.2K0.07%00.0%Unchanged
Parkside Financial Bank & Trust884$393.6K0.04%00.0%Unchanged
Forza Wealth Management, LLC881$392.2K0.16%00.0%Unchanged
Wealthspire Advisors, LLC881$392.1K0.00%+151+20.7%Added
Portfolio Design Labs, LLC880$391.8K0.08%−856−49.3%Reduced
Ellevest, Inc.877$390.4K0.06%−231−20.8%Reduced
Prescott Group Capital Management, L.L.C.869$386.9K0.05%+272+45.6%Added
George Kaiser Family Foundation869$386.9K0.06%+272+45.6%Added
Pinnacle Wealth Planning Services, Inc.868$386.4K0.05%−218−20.1%Reduced
Douglass Winthrop Advisors, LLC868$386.4K0.01%00.0%Unchanged
Severin Investments, LLC867$385.8K0.36%−12−1.4%Reduced
Lockerman Financial Group, Inc.863$384.2K0.52%+15+1.8%Added
Sentry Investment Management LLC821$383.0K0.21%00.0%Unchanged
Fulton Bank, N.A.847$377.1K0.01%+274+47.8%Added
BridgePort Financial Solutions, LLC843$375.3K0.12%+50+6.3%Added
Ancora Advisors, LLC836$372.3K0.01%−2−0.2%Reduced
WSFS Capital Management, LLC826$367.7K0.02%+370+81.1%Added
Opinicus Capital, Inc.822$366.0K0.28%+3+0.4%Added
Founders Financial Alliance, LLC819$364.6K0.08%−49−5.6%Reduced
LVW Advisors, LLC813$361.9K0.04%+19+2.4%Added
Larson Financial Group LLC811$361.1K0.01%−25−3.0%Reduced
Stock Yards Bank & Trust Co809$360.2K0.01%+295+57.4%Added
One Wealth Capital Management, LLC803$357.5K0.17%+21+2.7%Added
Parsonex Advisory Services, Inc.800$356.2K0.30%+800New
Soltis Investment Advisors LLC796$354.2K0.03%−89−10.1%Reduced
Boston Family Office LLC796$354.0K0.02%+345+76.5%Added
Zhang Financial LLC792$352.8K0.02%−524−39.8%Reduced
Everpar Advisors LLC792$352.6K0.16%+44+5.9%Added
ICONIQ Capital, LLC790$351.7K0.01%−450−36.3%Reduced
Delta Financial Advisors LLC788$350.8K0.12%+106+15.5%Added
Newman Dignan & Sheerar, Inc.786$349.9K0.08%+25+3.3%Added
Cercano Management LLC780$347.3K0.01%00.0%Unchanged
Banque Transatlantique SA776$346.3K0.01%−48−5.8%Reduced
Turtle Creek Wealth Advisors, LLC777$345.9K0.04%+777New