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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Essex Financial Services, Inc.772$343.7K0.02%−5−0.6%Reduced
Ausdal Financial Partners, Inc.770$342.8K0.02%−10−1.3%Reduced
denkapparat Operations GmbH766$341.0K0.27%−460−37.5%Reduced
One Capital Management, LLC766$341.0K0.01%+204+36.3%Added
Childress Capital Advisors, LLC760$338.5K0.09%−40−5.0%Reduced
Pinnacle Wealth Management Advisory Group, LLC757$337.0K0.03%+26+3.6%Added
MUFG Securities EMEA plc757$337.0K0.02%+757New
Financial Symmetry Inc755$336.3K0.17%00.0%Unchanged
Moss Adams Wealth Advisors LLC751$334.5K0.03%−112−13.0%Reduced
Northstar Asset Management LLC750$333.9K0.08%00.0%Unchanged
Abundance Wealth Counselors746$332.0K0.06%+100+15.5%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP744$331.2K0.00%+50+7.2%Added
Mitchell McLeod Pugh & Williams Inc742$330.3K0.06%+230+44.9%Added
Regions Financial Corp737$328.1K0.00%+30+4.2%Added
Norris Financial Group, LLC736$327.7K0.13%+736New
Bourgeon Capital Management LLC735$327.2K0.06%−632−46.2%Reduced
Nicholas Hoffman & Company, LLC.732$325.9K0.01%00.0%Unchanged
Castleark Management LLC730$325.0K0.01%−46,309−98.4%Reduced
Wedgewood Investors Inc720$320.5K0.37%00.0%Unchanged
Putney Financial Group LLC719$320.1K0.32%−196−21.4%Reduced
Leeward Financial Partners, LLC716$318.8K0.10%+58+8.8%Added
Sage Capital Advisors,llc715$318.1K0.08%+114+19.0%Added
Investment Advisory Group, LLC712$317.0K0.10%−5−0.7%Reduced
Seven Mile Advisory712$317.0K0.19%+3+0.4%Added
FourThought Financial Partners, LLC711$316.5K0.03%+50+7.6%Added
Fort Point Capital Partners LLC708$315.2K0.03%+34+5.0%Added
Grimes & Company, Inc.708$315.1K0.01%+2+0.3%Added
Meridian Wealth Management, LLC707$314.8K0.01%+87+14.0%Added
One Charles Private Wealth Services, LLC704$313.4K0.09%+704New
Essex Savings Bank704$313.4K0.07%+13+1.9%Added
Nautilus Advisors LLC701$312.1K0.23%+235+50.4%Added
Venture Visionary Partners LLC694$309.0K0.01%+5+0.7%Added
Fairfield, Bush & Co.691$307.6K0.17%00.0%Unchanged
HBK Sorce Advisory LLC690$307.2K0.01%+96+16.2%Added
Costello Asset Management, INC689$306.7K0.12%+24+3.6%Added
GK Wealth Management LLC689$306.7K0.30%+689New
Fox Hill Wealth Management683$304.1K0.16%+6+0.9%Added
Cullen/Frost Bankers, Inc.682$303.6K0.00%−345−33.6%Reduced
William Mack & Associates, Inc.682$303.6K0.19%00.0%Unchanged
Ewa, LLC681$303.2K0.10%+97+16.6%Added
Guerra Pan Advisors, LLC680$302.7K0.20%+86+14.5%Added
Perpetual Ltd679$302.3K0.00%+56+9.0%Added
Driehaus Capital Management LLC677$301.4K0.00%−431−38.9%Reduced
Zullo Investment Group, Inc.677$301.4K0.12%−126−15.7%Reduced
Versant Capital Management, Inc674$300.1K0.05%+47+7.5%Added
May Hill Capital, LLC673$299.6K0.10%+40+6.3%Added
KC Investment Advisors, LLC672$299.2K0.10%−1−0.1%Reduced
Capital Market Strategies LLC670$298.3K0.21%−350−34.3%Reduced
Stanley-Laman Group, Ltd.668$297.4K0.04%−334−33.3%Reduced
Onefund, LLC668$297.0K0.21%−9−1.3%Reduced
Kempen Capital Management N.V.663$295.2K0.00%−35−5.0%Reduced
Alpha Zero LLC661$294.3K0.19%+56+9.3%Added
Sivia Capital Partners, LLC657$292.5K0.10%−69−9.5%Reduced
Cromwell Holdings LLC656$292.1K0.18%+16+2.5%Added
Inscription Capital, LLC641$285.4K0.04%+79+14.1%Added
Relyea Zuckerberg Hanson LLC637$283.6K0.03%−125−16.4%Reduced
Syverson Strege & Co635$282.7K0.07%+635New
Cim, LLC633$281.8K0.04%+158+33.3%Added
AA Financial Advisors, LLC632$281.4K0.06%+632New
Financial Engines Advisors L.L.C.625$278.0K0.00%+625New
Mesirow Financial Investment Management, Inc.624$277.8K0.01%−5−0.8%Reduced
Western Wealth Management, LLC621$276.5K0.02%−70−10.1%Reduced
MONECO Advisors, LLC619$275.8K0.03%00.0%Unchanged
Sanibel Captiva Trust Company, Inc.617$274.7K0.01%−42−6.4%Reduced
Nicolet Bankshares Inc617$274.7K0.05%00.0%Unchanged
Sittner & Nelson, LLC615$273.8K0.11%+17+2.8%Added
First American Bank614$273.4K0.02%00.0%Unchanged
Diversified Trust Co613$272.9K0.01%−19−3.0%Reduced
Warren Street Wealth Advisors, LLC609$271.1K0.09%+100+19.6%Added
ASB Consultores, LLC608$270.7K0.18%+32+5.6%Added
Resurgent Financial Advisors LLC607$270.2K0.15%+6+1.0%Added
Focus Financial Network, Inc.606$269.8K0.01%+33+5.8%Added
Kelly Lawrence W & Associates Inc605$269.3K0.07%00.0%Unchanged
Aries Wealth Management605$269.3K0.07%00.0%Unchanged
ICW Investment Advisors LLC604$268.7K0.11%+29+5.0%Added
Tritonpoint Wealth, LLC601$267.6K0.02%−3−0.5%Reduced
Capital Performance Advisors LLP601$267.5K0.05%+59+10.9%Added
Corient IA LLC600$267.1K0.16%−100−14.3%Reduced
McAdam, LLC600$267.1K0.01%+84+16.3%Added
Keudell/Morrison Wealth Management597$265.8K0.06%−45−7.0%Reduced
Chesley Taft & Associates LLC596$265.3K0.01%+110+22.6%Added
United Advisor Group, LLC594$264.4K0.05%+594New
Lion Street Advisors, LLC592$263.6K0.08%−2−0.3%Reduced
Ronald Blue Trust, Inc.592$263.6K0.00%+19+3.3%Added
Icapital Wealth LLC591$263.1K0.15%00.0%Unchanged
Whipplewood Advisors, LLC589$262.2K0.14%+5+0.9%Added
Bartlett & Co. Wealth Management LLC587$261.3K0.00%00.0%Unchanged
JGP Global Gestao de Recursos Ltda.581$258.7K0.13%−2−0.3%Reduced
Independence Bank of Kentucky576$256.4K0.04%+47+8.9%Added
Cura Wealth Advisors, LLC575$256.0K0.12%+575New
RFG Advisory, LLC571$254.3K0.01%−186−24.6%Reduced
Midwest Trust Co571$254.2K0.00%+571New
Hanson & Doremus Investment Management570$254.0K0.03%+200+54.1%Added
TBH Global Asset Management, LLC569$253.3K0.05%−44−7.2%Reduced
Global Trust Asset Management, LLC568$253.1K0.14%−65−10.3%Reduced
Heartwood Wealth Advisors LLC568$252.9K0.03%+30+5.6%Added
Asset Allocation & Management Company, LLC567$252.0K0.12%00.0%Unchanged
Green Alpha Advisors, LLC565$251.5K0.24%−103−15.4%Reduced
LRI Investments, LLC562$250.2K0.02%−170−23.2%Reduced
Pinebridge Investments, L.P.562$250.2K0.00%−13,634−96.0%Reduced