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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Anchor Investment Management, LLC1,617$719.9K0.06%+2+0.1%Added
Resources Investment Advisors, LLC.1,615$719.2K0.01%−140−8.0%Reduced
Frisch Financial Group, Inc.1,614$719.0K0.18%+1,614New
Vista Investment Management1,614$718.6K0.27%−40−2.4%Reduced
Nomura Holdings Inc1,604$714.1K0.01%−3,130−66.1%Reduced
Journey Strategic Wealth LLC1,603$713.7K0.02%+809+101.9%Added
First Citizens Bank & Trust Co1,603$713.7K0.01%−2,594−61.8%Reduced
Perfromance Wealth Partners, LLC1,600$712.3K0.02%−3−0.2%Reduced
BKD Wealth Advisors, LLC1,600$712.3K0.02%+152+10.5%Added
Peapack Gladstone Financial Corp1,596$711.0K0.01%−181−10.2%Reduced
Fukoku Mutual Life Insurance Co1,589$707.4K0.05%−226−12.5%Reduced
First Manhattan Co1,585$705.6K0.00%+30+1.9%Added
J.W. Cole Advisors, Inc.1,584$705.2K0.01%−169−9.6%Reduced
Lord, Abbett & Co. LLC1,572$700.0K0.00%−1,375−46.7%Reduced
Gsa Capital Partners LLP1,571$699.0K0.05%+837+114.0%Added
Sava Infond d.o.o.1,570$699.0K0.11%00.0%Unchanged
LOM Asset Management Ltd1,565$697.0K0.24%+1,565New
Exencial Wealth Advisors, LLC1,560$694.5K0.02%−76−4.6%Reduced
Resonant Capital Advisors, LLC1,558$693.6K0.04%+108+7.4%Added
Destination Wealth Management1,553$691.4K0.02%−1,724−52.6%Reduced
Lantern Wealth Advisors, LLC1,550$690.1K0.41%+1,550New
IHT Wealth Management, LLC1,547$688.7K0.02%+5+0.3%Added
Conning Inc.1,544$687.4K0.02%−42−2.6%Reduced
Renaissance Group LLC1,519$676.3K0.03%−195−11.4%Reduced
Global Assets Advisory, LLC1,484$671.0K0.26%−1,124−43.1%Reduced
Spinnaker Trust1,505$670.0K0.04%+260+20.9%Added
Scott Marsh Financial, LLC1,504$669.6K0.25%+1,504New
Kensington Investment Counsel, LLC1,503$669.1K0.29%+7+0.5%Added
Moloney Securities Asset Management, LLC1,498$666.9K0.08%−300−16.7%Reduced
Holderness Investments Co1,497$666.5K0.14%+133+9.8%Added
Arcataur Capital Management LLC1,496$666.0K0.21%00.0%Unchanged
Avantax Planning Partners, Inc.1,489$662.9K0.02%+295+24.7%Added
SBI Securities Co., Ltd.1,488$662.5K0.02%+9+0.6%Added
Private Wealth Partners, LLC1,485$661.1K0.05%00.0%Unchanged
Harbor Investment Advisory, LLC1,474$656.2K0.06%00.0%Unchanged
First Pacific Financial1,465$652.2K0.10%−116−7.3%Reduced
Pitcairn Co1,457$648.7K0.04%−328−18.4%Reduced
Sovran Advisors, LLC1,385$645.9K0.07%−4,104−74.8%Reduced
CoreCap Advisors, LLC1,442$642.0K0.03%+641+80.0%Added
Baxter Bros Inc1,441$641.5K0.08%+213+17.3%Added
Gibbs Wealth Management1,433$638.0K0.12%+435+43.6%Added
NorthCrest Asset Manangement, LLC1,380$634.2K0.02%−9−0.6%Reduced
Arete Wealth Advisors, LLC1,417$631.0K0.04%−29−2.0%Reduced
Legacy Wealth Asset Management, LLC1,416$630.4K0.16%−13−0.9%Reduced
Mayflower Financial Advisors, LLC1,413$629.1K0.09%−78−5.2%Reduced
Sage Mountain Advisors LLC1,405$625.4K0.04%+163+13.1%Added
Reuter James Wealth Management, LLC1,379$613.9K0.10%−188−12.0%Reduced
Kessler Investment Group, LLC1,373$611.3K0.25%00.0%Unchanged
Hantz Financial Services, Inc.1,366$608.0K0.01%−18−1.3%Reduced
Hancock Whitney Corp1,362$606.4K0.01%+19+1.4%Added
PDT Partners, LLC1,353$602.4K0.03%−6,763−83.3%Reduced
Nabity-Jensen Investment Management Inc1,348$600.1K0.44%00.0%Unchanged
Independent Financial Group, LLC1,346$599.2K0.02%−993−42.5%Reduced
Pine Valley Investments Ltd Liability Co1,341$597.0K0.04%00.0%Unchanged
BankPlus Trust Department1,341$597.0K0.18%−15−1.1%Reduced
Advisors Capital Management, LLC1,326$590.5K0.01%+55+4.3%Added
Insigneo Advisory Services, LLC1,325$589.9K0.05%+238+21.9%Added
Whalen Wealth Management Inc.1,324$589.4K0.37%+1,324New
Perennial Investment Advisors, LLC1,323$589.0K0.06%+80+6.4%Added
American Trust1,311$583.7K0.05%+9+0.7%Added
Souders Financial Advisors1,309$582.8K0.07%+222+20.4%Added
Koshinski Asset Management, Inc.1,300$578.8K0.04%+2+0.2%Added
Paces Ferry Wealth Advisors, LLC1,291$574.8K0.26%−61−4.5%Reduced
Keel Point, LLC1,288$573.4K0.04%+104+8.8%Added
Angeles Wealth Management, LLC1,284$571.6K0.04%+29+2.3%Added
Kovack Advisors, Inc.1,280$569.9K0.06%+24+1.9%Added
Wakefield Asset Management LLLP1,276$568.1K0.16%00.0%Unchanged
Alta Advisers Ltd1,271$565.8K0.20%00.0%Unchanged
Harel Insurance Investments & Financial Services Ltd.1,270$565.0K0.01%+504+65.8%Added
Total Clarity Wealth Management, Inc.1,262$561.8K0.16%+50+4.1%Added
BOK Financial Private Wealth, Inc.1,258$560.1K0.04%−531−29.7%Reduced
RMB Capital Management, LLC1,256$559.0K0.01%+835+198.3%Added
Fragasso Group Inc.1,254$558.3K0.04%+143+12.9%Added
Pensionmark Financial Group, LLC1,253$557.9K0.01%+379+43.4%Added
Breed's Hill Capital LLC1,253$557.8K0.27%+27+2.2%Added
Rathbone Brothers plc1,251$556.9K0.00%00.0%Unchanged
Merrion Investment Management Co, LLC1,250$556.5K0.36%00.0%Unchanged
Drive Wealth Management, LLC1,249$555.9K0.12%+176+16.4%Added
Moneta Group Investment Advisors LLC1,246$554.9K0.01%+74+6.3%Added
PDS Planning, Inc1,243$553.4K0.04%+85+7.3%Added
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors1,240$552.0K0.08%−87−6.6%Reduced
Paladin Wealth, LLC1,240$552.0K0.43%+1,240New
Alps Advisors Inc1,239$551.6K0.00%−78−5.9%Reduced
Platform Technology Partners1,234$549.4K0.14%−31−2.5%Reduced
Morningstar Investment Management LLC1,230$548.0K0.05%+1,230New
TrueWealth Advisors, LLC1,223$544.5K0.16%+135+12.4%Added
Green Harvest Asset Management LLC1,220$543.1K0.01%−24−1.9%Reduced
Holocene Advisors, LP1,216$541.4K0.00%00.0%Unchanged
Willner & Heller, LLC1,216$541.4K0.46%+60+5.2%Added
Great Valley Advisor Group, Inc.1,211$539.5K0.01%−10,372−89.5%Reduced
Chicago Partners Investment Group LLC1,124$536.1K0.02%+176+18.6%Added
First Commonwealth Financial Corp1,202$535.1K0.12%00.0%Unchanged
Generali Investments Towarzystwo Funduszy Inwestycyjnych1,200$534.2K0.28%00.0%Unchanged
Avidian Wealth Solutions, LLC1,192$530.7K0.02%−33−2.7%Reduced
Kestra Investment Management, LLC1,135$529.0K0.01%+538+90.1%Added
Catalyst Financial Partners LLC1,170$520.9K0.06%−191−14.0%Reduced
Founders Financial Securities LLC1,155$514.2K0.04%−12−1.0%Reduced
Bridgewater Advisors Inc.1,097$513.9K0.04%−16−1.4%Reduced
LCM Capital Management Inc1,148$511.1K0.27%+4+0.3%Added
Keynote Financial Services LLC1,145$509.8K0.34%+40+3.6%Added