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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
GraniteShares Advisors LLC2,286$1.02M0.63%−28−1.2%Reduced
Sigma Planning Corp2,280$1.01M0.03%−34−1.5%Reduced
Brown Financial Advisors2,253$1.00M0.39%+2,253New
Cravens & Co Advisors, LLC2,241$997.7K0.74%+63+2.9%Added
Equitable Holdings, Inc.2,237$995.9K0.01%+85+3.9%Added
Advisors Preferred, LLC2,200$994.8K0.16%00.0%Unchanged
S-Bank Fund Management Ltd2,233$994.1K0.15%−157−6.6%Reduced
Kane Investment Management, Inc.2,231$993.2K0.52%−89−3.8%Reduced
Global Retirement Partners, LLC2,205$981.9K0.02%+2,205New
HM Payson & Co2,198$978.5K0.02%−3,623−62.2%Reduced
Koa Wealth Management, LLC2,180$970.5K0.77%+108+5.2%Added
Regal Investment Advisors LLC2,171$966.3K0.07%+366+20.3%Added
Arkadios Wealth Advisors2,152$958.2K0.03%+697+47.9%Added
Alliance Wealth Advisors, LLC2,145$955.0K0.24%+572+36.4%Added
Mitchell & Pahl Private Wealth, LLC2,144$954.5K0.42%−5−0.2%Reduced
Impact Capital Partners LLC2,139$952.3K0.31%−337−13.6%Reduced
Evercore Wealth Management, LLC2,128$947.4K0.01%+27+1.3%Added
MAI Capital Management2,127$946.8K0.01%+209+10.9%Added
Presilium Private Wealth, LLC2,124$945.6K0.19%00.0%Unchanged
Hohimer Wealth Management, LLC2,123$945.2K0.17%+26+1.2%Added
Ashton Thomas Private Wealth, LLC2,122$944.7K0.03%−220−9.4%Reduced
Forum Financial Management, LP2,094$932.4K0.01%00.0%Unchanged
Formidable Asset Management, LLC2,019$931.1K0.16%−82−3.9%Reduced
Schmidt P J Investment Management Inc2,082$926.9K0.16%+150+7.8%Added
Csenge Advisory Group2,096$926.5K0.05%−85−3.9%Reduced
Integrated Advisors Network LLC2,080$926.2K0.04%−76−3.5%Reduced
Fort Sheridan Advisors LLC2,076$924.2K0.13%−352−14.5%Reduced
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management2,052$913.6K0.02%+215+11.7%Added
Pflug Koory, LLC2,046$910.9K0.46%+52+2.6%Added
Guidance Capital, Inc1,943$897.9K0.26%−332−14.6%Reduced
Qtron Investments LLC2,016$897.5K0.11%00.0%Unchanged
Allegheny Financial Group LTD2,000$890.4K0.20%00.0%Unchanged
Mystic Asset Management, Inc.2,000$890.4K0.22%00.0%Unchanged
Veracity Capital LLC1,994$887.7K0.31%−108−5.1%Reduced
Towarzystwo Funduszy Inwestycyjnych Pzu SA1,994$887.7K0.25%−75−3.6%Reduced
IFG Advisory, LLC1,985$883.7K0.04%+3+0.2%Added
Holt Capital Advisors, L.L.C. dba Holt Capital Partners, L.P.1,977$880.2K0.15%00.0%Unchanged
Prossimo Advisors, LLC1,975$879.0K0.71%−80−3.9%Reduced
Bradley Foster & Sargent Inc1,971$877.5K0.01%−121−5.8%Reduced
Community Bank, N.A.1,964$874.4K0.11%+727+58.8%Added
Annis Gardner Whiting Capital Advisors, LLC1,961$873.0K0.30%+22+1.1%Added
Bryce Point Capital, LLC1,956$870.8K0.74%+710+57.0%Added
Proficio Capital Partners LLC1,955$870.4K0.05%−124−6.0%Reduced
Menard Financial Group LLC1,951$868.6K0.52%+169+9.5%Added
Malaga Cove Capital, LLC1,912$851.2K0.33%+123+6.9%Added
Goelzer Investment Management, Inc.1,899$845.4K0.05%+6+0.3%Added
Geneos Wealth Management Inc.1,892$842.3K0.02%+65+3.6%Added
Badgley Phelps Wealth Managers, LLC1,887$840.1K0.02%+22+1.2%Added
Everhart Financial Group, Inc.1,881$837.4K0.10%−328−14.8%Reduced
Livforsakringsbolaget Skandia, Omsesidigt1,880$836.7K0.04%−25,740−93.2%Reduced
Summit Financial, LLC1,873$833.9K0.02%+233+14.2%Added
Spears Abacus Advisors LLC1,872$833.4K0.02%−37−1.9%Reduced
PFG Investments, LLC1,872$833.4K0.05%+60+3.3%Added
Groesbeck Investment Management Corp1,859$828.0K1.45%−10−0.5%Reduced
Legal Advantage Investments, Inc.1,848$822.7K0.38%00.0%Unchanged
Aviso Financial Inc.1,844$820.9K0.04%−6−0.3%Reduced
Breakwater Capital Group1,839$818.7K0.13%+53+3.0%Added
Premier Path Wealth Partners, LLC1,835$817.1K0.11%+45+2.5%Added
Fifth Third Wealth Advisors LLC1,826$812.9K0.03%−8−0.4%Reduced
We Are One Seven, LLC1,822$811.2K0.03%+43+2.4%Added
Capital Advisors Wealth Management, LLC1,821$810.7K0.13%−47−2.5%Reduced
Whittier Trust Co1,820$810.3K0.01%−104−5.4%Reduced
Aureus Asset Management, LLC1,818$809.4K0.05%−335−15.6%Reduced
Oak Ridge Investments LLC1,816$808.5K0.06%−17−0.9%Reduced
Appleton Partners Inc1,808$805.0K0.06%+15+0.8%Added
Strategic Blueprint, LLC1,807$804.5K0.04%+309+20.6%Added
Acima Private Wealth, LLC1,806$804.0K0.27%00.0%Unchanged
IFP Advisors, Inc1,590$800.1K0.02%−1,074−40.3%Reduced
1248 Management, LLC1,795$799.1K0.30%00.0%Unchanged
Checchi Capital Advisers, LLC1,794$798.7K0.06%−41−2.2%Reduced
Alta Wealth Advisors LLC1,792$797.8K0.38%00.0%Unchanged
Brookwood Investment Group LLC1,779$792.0K0.13%+11+0.6%Added
Howland Capital Management LLC1,776$790.7K0.03%−199−10.1%Reduced
Great Diamond Partners, LLC1,776$790.7K0.17%+423+31.3%Added
Wrapmanager Inc1,774$789.8K0.19%−69−3.7%Reduced
Strategic Investment Advisors1,774$788.4K0.08%+39+2.2%Added
Altfest L J & Co Inc1,766$786.2K0.09%+120+7.3%Added
Catalytic Wealth RIA, LLC1,765$785.8K0.06%+1,314+291.4%Added
Hartford Funds Management Co LLC1,754$781.9K0.07%+394+29.0%Added
CX Institutional1,754$781.0K0.03%−33−1.8%Reduced
Transcend Wealth Collective, LLC1,744$776.3K0.06%−1,522−46.6%Reduced
Continuum Advisory, LLC1,739$774.2K0.09%+74+4.4%Added
Fortis Capital Advisors, LLC1,735$772.4K0.14%−19−1.1%Reduced
Prudent Man Advisors, LLC1,735$772.4K0.25%+376+27.7%Added
Triangle Securities Wealth Management1,728$769.3K0.19%+10+0.6%Added
Great Lakes Retirement, Inc.1,724$767.5K0.09%−5−0.3%Reduced
Alpha Family Trust1,720$765.7K0.38%00.0%Unchanged
Rehmann Capital Advisory Group1,708$760.4K0.05%+144+9.2%Added
Raab & Moskowitz Asset Management LLC1,701$757.3K0.18%00.0%Unchanged
Advisory Alpha, LLC1,701$757.3K0.02%+187+12.4%Added
Kornitzer Capital Management Inc1,700$756.8K0.02%+1,032+154.5%Added
Oxler Private Wealth LLC1,674$745.3K0.23%00.0%Unchanged
AdvisorNet Financial, Inc1,674$745.3K0.05%+201+13.6%Added
GTS Securities LLC1,648$733.7K0.03%−418−20.2%Reduced
Eastern Bank1,635$727.9K0.01%+25+1.6%Added
Campbell Newman Asset Management Inc1,626$723.9K0.06%−5−0.3%Reduced
Clarius Group, LLC1,625$723.5K0.04%−193−10.6%Reduced
KRS Capital Management, LLC1,622$722.1K0.48%−115−6.6%Reduced
Flagship Harbor Advisors, LLC1,620$721.2K0.03%+85+5.5%Added
Lee Johnson Capital Management, LLC1,619$720.8K0.25%+1,619New