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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 5 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
214
+20 vs. Q4 2025
Shares held
118.5M
+2.37M (+2.0%) vs. Q4 2025
Total value
$3.72B
+$839.3M (+29.1%) vs. Q4 2025
New holders
44
65 more added
Sold out
24
66 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 214 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ1 2026: $3.72B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding EWTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Morgan Stanley2,246,028$70.7M0.00%−664,853−22.8%Reduced
Braidwell LP2,347,583$73.9M2.47%−2,863,248−54.9%Reduced
Cormorant Asset Management, LP3,260,000$102.7M5.18%−25,000−0.8%Reduced
Vanguard Capital Management LLC3,788,161$119.3M0.00%+3,788,161New
Perceptive Advisors LLC4,423,974$139.4M2.75%−34,000−0.8%Reduced
Siren, L.L.C.4,430,263$139.6M3.87%−99,727−2.2%Reduced
Driehaus Capital Management LLC4,477,942$141.1M1.04%+286,749+6.8%Added
Novo Holdings A/S5,350,000$168.5M13.65%00.0%Unchanged
Janus Henderson Group PLC5,915,556$186.3M0.09%+1,348,706+29.5%Added
BlackRock, Inc.6,472,991$203.9M0.00%−157,585−2.4%Reduced
Baker Bros. Advisors LP6,575,940$207.1M1.19%00.0%Unchanged
Paradigm Biocapital Advisors LP7,365,038$232.0M4.74%+823,828+12.6%Added
Ra Capital Management, L.P.10,428,437$328.5M3.48%00.0%Unchanged
OrbiMed Advisors LLC15,518,492$488.8M11.11%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)0$00.00%−765,694−100.0%Sold out
Eversept Partners, LP0$00.00%−337,340−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−151,905−100.0%Sold out
Exome Asset Management LLC0$00.00%−100,046−100.0%Sold out
Jump Financial, LLC0$00.00%−79,915−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−41,584−100.0%Sold out
Verition Fund Management LLC0$00.00%−33,591−100.0%Sold out
Diadema Partners LP0$00.00%−30,000−100.0%Sold out
Optimize Financial Inc0$00.00%−27,679−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−18,672−100.0%Sold out
Winton Group Ltd0$00.00%−14,184−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−14,085−100.0%Sold out
VARCOV Co.0$00.00%−10,034−100.0%Sold out
Nomura Holdings Inc0$00.00%−10,000−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−9,849−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−9,468−100.0%Sold out
Quest Partners LLC0$00.00%−7,143−100.0%Sold out
Canada Pension Plan Investment Board0$00.00%−3,900−100.0%Sold out
Amalgamated Bank0$00.00%−2,120−100.0%Sold out
Quantbot Technologies LP0$00.00%−774−100.0%Sold out
Northwestern Mutual Wealth Management Co0$00.00%−489−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−344−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−87−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−11−100.0%Sold out
Vanguard Group Inc––––Not filed
Norges Bank––––Not filed
Oracle Investment Management Inc––––Not filed
Comerica Bank––––Not filed
CIBC Private Wealth Group, LLC––––Not filed