Edgewise Therapeutics, Inc.
EWTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001710072
In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Edgewise Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 173
- −5 vs. Q2 2025
- Shares held
- 112.0M
- −6.73M (−5.7%) vs. Q2 2025
- Total value
- $1.82B
- +$259.7M (+16.7%) vs. Q2 2025
- New holders
- 17
- 59 more added
- Sold out
- 22
- 62 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 226 | $4.82B |
| Q1 2026 | 214 | $3.72B |
| Q4 2025 | 199 | $3.02B |
| Q3 2025 | 173 | $1.82B |
| Q2 2025 | 179 | $1.56B |
| Q1 2025 | 193 | $2.32B |
| Q4 2024 | 201 | $2.64B |
| Q3 2024 | 177 | $2.71B |
| Q2 2024 | 140 | $1.83B |
| Q1 2024 | 129 | $1.67B |
| Q4 2023 | 116 | $871.4M |
| Q3 2023 | 85 | $392.2M |
| Q2 2023 | 95 | $538.8M |
| Q1 2023 | 85 | $443.1M |
| Q4 2022 | 90 | $594.1M |
| Q3 2022 | 94 | $633.5M |
| Q2 2022 | 78 | $405.7M |
| Q1 2022 | 72 | $523.5M |
| Q4 2021 | 58 | $769.4M |
| Q3 2021 | 48 | $795.8M |
| Q2 2021 | 46 | $1.03B |
| Q1 2021 | 31 | $1.48B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 68,720 | $1.11M | 0.00% | −8,896−11.5% | Reduced |
| Jane Street Group, LLC | 69,998 | $1.14M | 0.00% | +19,813+39.5% | Added |
| Squarepoint Ops LLC | 75,276 | $1.22M | 0.00% | +75,276 | New |
| Alliancebernstein L.P. | 77,260 | $1.25M | 0.00% | 00.0% | Unchanged |
| Jump Financial, LLC | 80,825 | $1.31M | 0.02% | −40,880−33.6% | Reduced |
| Moody Aldrich Partners LLC | 82,941 | $1.35M | 0.26% | −16,907−16.9% | Reduced |
| New York State Common Retirement Fund | 83,437 | $1.35M | 0.00% | −10,371−11.1% | Reduced |
| DekaBank Deutsche Girozentrale | 80,000 | $1.55M | 0.00% | 00.0% | Unchanged |
| Swiss National Bank | 101,900 | $1.65M | 0.00% | +11,900+13.2% | Added |
| Rhumbline Advisers | 104,829 | $1.70M | 0.00% | −7,654−6.8% | Reduced |
| Quantum Private Wealth, LLC | 105,874 | $1.72M | 0.50% | +5,100+5.1% | Added |
| Gsa Capital Partners LLP | 113,243 | $1.84M | 0.15% | +85,967+315.2% | Added |
| UBS Group AG | 114,128 | $1.85M | 0.00% | −56,854−33.3% | Reduced |
| Wellington Management Group LLP | 114,531 | $1.86M | 0.00% | +1,961+1.7% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 132,503 | $2.15M | 0.00% | +325+0.2% | Added |
| UBS Asset Management Americas Inc | 139,112 | $2.26M | 0.00% | −52,494−27.4% | Reduced |
| Schroder Investment Management Group | 151,062 | $2.38M | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 154,896 | $2.51M | 0.00% | +7,371+5.0% | Added |
| Nuveen, LLC | 172,707 | $2.80M | 0.00% | −144,466−45.5% | Reduced |
| Exome Asset Management LLC | 173,439 | $2.81M | 1.86% | +48,969+39.3% | Added |
| Bank of New York Mellon Corp | 204,242 | $3.31M | 0.00% | −8,616−4.0% | Reduced |
| HighVista Strategies LLC | 208,101 | $3.38M | 0.83% | +138,378+198.5% | Added |
| DAFNA Capital Management LLC | 213,736 | $3.47M | 0.86% | −24,404−10.2% | Reduced |
| Neuberger Berman Group LLC | 219,646 | $3.56M | 0.00% | +54,111+32.7% | Added |
| Candriam Luxembourg S.C.A. | 221,159 | $3.59M | 0.02% | −2,831−1.3% | Reduced |
| Woodline Partners LP | 224,190 | $3.64M | 0.02% | −872,673−79.6% | Reduced |
| Barclays PLC | 234,650 | $3.81M | 0.00% | −46,600−16.6% | Reduced |
| Kennedy Capital Management, Inc. | 250,622 | $4.07M | 0.09% | −1,902−0.8% | Reduced |
| FMR LLC | 253,325 | $4.11M | 0.00% | −217,392−46.2% | Reduced |
| Kynam Capital Management, LP | 253,979 | $4.12M | 0.31% | 00.0% | Unchanged |
| Sio Capital Management, LLC | 307,181 | $4.98M | 1.26% | −232,549−43.1% | Reduced |
| Bank of America Corp | 321,132 | $5.21M | 0.00% | +66,703+26.2% | Added |
| Granahan Investment Management Inc | 339,617 | $5.51M | 0.23% | −65,861−16.2% | Reduced |
| Tang Capital Management LLC | 431,300 | $7.00M | 0.27% | 00.0% | Unchanged |
| Victory Capital Management Inc | 498,646 | $8.09M | 0.01% | +55,809+12.6% | Added |
| Opaleye Management Inc. | 500,000 | $8.11M | 1.15% | +10,000+2.0% | Added |
| Eversept Partners, LP | 502,234 | $8.15M | 0.62% | +109,495+27.9% | Added |
| Sofinnova Investments, Inc. | 520,240 | $8.44M | 0.52% | −196,633−27.4% | Reduced |
| Goldman Sachs Group Inc | 527,827 | $8.56M | 0.00% | −103,916−16.4% | Reduced |
| Citigroup Inc | 538,453 | $8.73M | 0.01% | −186,446−25.7% | Reduced |
| Parkman Healthcare Partners LLC | 550,173 | $8.92M | 0.98% | −97,158−15.0% | Reduced |
| Qube Research & Technologies Ltd | 555,713 | $9.01M | 0.01% | +55,796+11.2% | Added |
| Eventide Asset Management, LLC | 568,310 | $9.22M | 0.15% | 00.0% | Unchanged |
| Northern Trust Corp | 587,882 | $9.54M | 0.00% | −15,016−2.5% | Reduced |
| Charles Schwab Investment Management Inc | 597,603 | $9.69M | 0.00% | +18,499+3.2% | Added |
| Standard Life Aberdeen plc | 619,878 | $10.1M | 0.02% | +176,559+39.8% | Added |
| D. E. Shaw & Co., Inc. | 677,561 | $11.0M | 0.01% | +82,129+13.8% | Added |
| Artisan Partners Limited Partnership | 718,175 | $11.6M | 0.02% | −660,893−47.9% | Reduced |
| Millennium Management LLC | 725,425 | $11.8M | 0.01% | −196,540−21.3% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 765,694 | $12.4M | 0.19% | −1,301,626−63.0% | Reduced |
| Morgan Stanley | 869,678 | $14.1M | 0.00% | +141,964+19.5% | Added |
| New Leaf Venture Partners, L.L.C. | 1,030,161 | $16.7M | 38.82% | 00.0% | Unchanged |
| American Century Companies Inc | 1,095,473 | $17.8M | 0.01% | +312,307+39.9% | Added |
| Dimensional Fund Advisors LP | 1,183,136 | $19.2M | 0.00% | +134,200+12.8% | Added |
| First Light Asset Management, LLC | 1,414,994 | $23.0M | 2.16% | −299,025−17.4% | Reduced |
| Integral Health Asset Management, LLC | 1,500,000 | $24.3M | 1.77% | +500,000+50.0% | Added |
| State Street Corp | 1,699,909 | $27.6M | 0.00% | −81,592−4.6% | Reduced |
| Geode Capital Management, LLC | 1,717,641 | $27.9M | 0.00% | −79,574−4.4% | Reduced |
| MPM Oncology Impact Management LP | 1,720,741 | $27.9M | 4.57% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 2,228,285 | $36.1M | 0.26% | +126,504+6.0% | Added |
| Bellevue Group AG | 2,775,997 | $45.0M | 0.94% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 3,795,894 | $61.6M | 1.78% | −844,055−18.2% | Reduced |
| Siren, L.L.C. | 3,897,099 | $63.2M | 2.47% | +736,801+23.3% | Added |
| Cormorant Asset Management, LP | 4,010,000 | $65.0M | 4.49% | −241,992−5.7% | Reduced |
| Vanguard Group Inc | 4,803,941 | $77.9M | 0.00% | −37,559−0.8% | Reduced |
| Janus Henderson Group PLC | 4,979,331 | $80.8M | 0.04% | −524,018−9.5% | Reduced |
| Braidwell LP | 5,210,831 | $84.5M | 2.51% | 00.0% | Unchanged |
| Novo Holdings A/S | 5,350,000 | $86.8M | 5.59% | 00.0% | Unchanged |
| Paradigm Biocapital Advisors LP | 6,170,131 | $100.1M | 2.96% | +27,787+0.5% | Added |
| BlackRock, Inc. | 6,351,487 | $103.0M | 0.00% | −429,559−6.3% | Reduced |
| Baker Bros. Advisors LP | 7,305,940 | $118.5M | 0.86% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 10,428,437 | $169.1M | 2.08% | +525,804+5.3% | Added |
| OrbiMed Advisors LLC | 15,518,492 | $251.7M | 6.04% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −975,000−100.0% | Sold out |
| Foresite Capital Management VI LLC | 0 | $0 | 0.00% | −585,000−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −284,551−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −86,882−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −78,280−100.0% | Sold out |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −76,493−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −60,739−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −55,292−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −44,069−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −41,663−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −41,463−100.0% | Sold out |
| Skandinaviska Enskilda Banken AB (publ) | 0 | $0 | 0.00% | −37,591−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −34,909−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −27,042−100.0% | Sold out |
| Numerai GP LLC | 0 | $0 | 0.00% | −22,353−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −13,561−100.0% | Sold out |
| Nebula Research & Development LLC | 0 | $0 | 0.00% | −13,219−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −10,712−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −6,100−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −1,314−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −311−100.0% | Sold out |
| Riggs Asset Managment Co. Inc. | 0 | $0 | 0.00% | −49−100.0% | Sold out |
| Norges Bank | – | – | – | – | Not filed |