Skip to main content

Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Edgewise Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
179
−11 vs. Q1 2025
Shares held
118.7M
+13.4M (+12.8%) vs. Q1 2025
Total value
$1.56B
−$763.4M (−32.9%) vs. Q1 2025
New holders
30
88 more added
Sold out
41
39 more reduced

3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 179 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ2 2025: $1.56B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding EWTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Alliancebernstein L.P.77,260$1.01M0.00%00.0%Unchanged
JPMorgan Chase & Co77,616$1.02M0.00%−13,752−15.1%Reduced
Twinbeech Capital LP78,280$1.03M0.02%−22,546−22.4%Reduced
Walleye Capital LLC86,882$1.14M0.01%+70,704+437.0%Added
Swiss National Bank90,000$1.18M0.00%+7,400+9.0%Added
New York State Common Retirement Fund93,808$1.23M0.00%+22,358+31.3%Added
Moody Aldrich Partners LLC99,848$1.31M0.25%−82,247−45.2%Reduced
Quantum Private Wealth, LLC100,774$1.32M0.43%+10,050+11.1%Added
Rhumbline Advisers112,483$1.47M0.00%+3,646+3.3%Added
Wellington Management Group LLP112,570$1.48M0.00%−733−0.6%Reduced
Campbell & CO Investment Adviser LLC114,181$1.50M0.09%+114,181New
Susquehanna International Group, LLP115,270$1.51M0.00%−61,396−34.8%Reduced
DekaBank Deutsche Girozentrale80,000$1.56M0.00%00.0%Unchanged
Jump Financial, LLC121,705$1.60M0.02%+121,705New
Exome Asset Management LLC124,470$1.63M1.35%+53,032+74.2%Added
Universal- Beteiligungs- und Servicegesellschaft mbH132,178$1.73M0.00%+42,753+47.8%Added
Deutsche Bank AG147,525$1.93M0.00%−228,535−60.8%Reduced
Schroder Investment Management Group151,062$1.98M0.00%+71,911+90.9%Added
Neuberger Berman Group LLC165,535$2.17M0.00%+63,354+62.0%Added
Schonfeld Strategic Advisors LLC167,340$2.19M0.02%−111,633−40.0%Reduced
UBS Group AG170,982$2.24M0.00%−72,914−29.9%Reduced
UBS Asset Management Americas Inc191,606$2.51M0.00%−81,251−29.8%Reduced
Bank of New York Mellon Corp212,858$2.79M0.00%+2,123+1.0%Added
Candriam Luxembourg S.C.A.223,990$2.94M0.02%−1,806−0.8%Reduced
DAFNA Capital Management LLC238,140$3.12M0.86%+55,000+30.0%Added
Kennedy Capital Management, Inc.252,524$3.31M0.08%+27,824+12.4%Added
Kynam Capital Management, LP253,979$3.33M0.36%+253,979New
Bank of America Corp254,429$3.34M0.00%−440,997−63.4%Reduced
Barclays PLC281,250$3.69M0.00%+172,688+159.1%Added
Voloridge Investment Management, LLC284,551$3.73M0.01%+284,551New
Federated Hermes, Inc.316,500$4.15M0.01%+316,420+395,525.0%Added
Nuveen, LLC317,173$4.16M0.00%+114,593+56.6%Added
Citadel Advisors LLC325,249$4.26M0.00%+227,971+234.4%Added
Eversept Partners, LP392,739$5.15M0.52%+392,739New
Granahan Investment Management Inc405,478$5.32M0.22%+187,811+86.3%Added
Tang Capital Management LLC431,300$5.65M0.29%+131,300+43.8%Added
Victory Capital Management Inc442,837$5.81M0.00%+442,837New
Standard Life Aberdeen plc443,319$5.81M0.01%+130,294+41.6%Added
FMR LLC470,717$6.17M0.00%+284,694+153.0%Added
Opaleye Management Inc.490,000$6.42M1.30%+95,000+24.1%Added
Qube Research & Technologies Ltd499,917$6.55M0.01%+102,344+25.7%Added
Sio Capital Management, LLC539,730$7.08M2.84%+539,730New
Eventide Asset Management, LLC568,310$7.45M0.13%00.0%Unchanged
Charles Schwab Investment Management Inc579,104$7.59M0.00%+57,843+11.1%Added
Foresite Capital Management VI LLC585,000$7.67M4.31%00.0%Unchanged
D. E. Shaw & Co., Inc.595,432$7.81M0.01%+454,884+323.7%Added
Northern Trust Corp602,898$7.90M0.00%−3,794−0.6%Reduced
Goldman Sachs Group Inc631,743$8.28M0.00%+265,099+72.3%Added
Parkman Healthcare Partners LLC647,331$8.49M0.98%+221,924+52.2%Added
Sofinnova Investments, Inc.716,873$9.40M0.64%+374,655+109.5%Added
Citigroup Inc724,899$9.50M0.01%+650,592+875.5%Added
Morgan Stanley727,714$9.54M0.00%+318,717+77.9%Added
American Century Companies Inc783,166$10.3M0.01%+3,400+0.4%Added
Millennium Management LLC921,965$12.1M0.01%+306,847+49.9%Added
Polar Capital Holdings Plc975,000$12.8M0.07%+725,000+290.0%Added
Integral Health Asset Management, LLC1,000,000$13.1M1.22%+325,000+48.1%Added
New Leaf Venture Partners, L.L.C.1,030,161$13.5M40.97%00.0%Unchanged
Dimensional Fund Advisors LP1,048,936$13.8M0.00%+381,437+57.1%Added
Woodline Partners LP1,096,863$14.4M0.08%+540.0%Added
Artisan Partners Limited Partnership1,379,068$18.1M0.03%+461,846+50.4%Added
First Light Asset Management, LLC1,714,019$22.5M2.91%−138,271−7.5%Reduced
MPM Oncology Impact Management LP1,720,741$22.6M3.91%+615,297+55.7%Added
State Street Corp1,781,501$23.4M0.00%+63,777+3.7%Added
Geode Capital Management, LLC1,797,215$23.6M0.00%+141,551+8.5%Added
Deerfield Management Company, L.P. (Series C)2,067,320$27.1M0.49%−11,189−0.5%Reduced
Driehaus Capital Management LLC2,101,781$27.6M0.22%+726,039+52.8%Added
Bellevue Group AG2,775,997$36.4M0.80%+1,347,068+94.3%Added
Siren, L.L.C.3,160,298$41.4M2.14%+1,463,854+86.3%Added
Cormorant Asset Management, LP4,251,992$55.7M4.15%+150,000+3.7%Added
Perceptive Advisors LLC4,639,949$60.8M2.28%−1,907,379−29.1%Reduced
Vanguard Group Inc4,841,500$63.5M0.00%+547,096+12.7%Added
Braidwell LP5,210,831$68.3M2.34%+2,752,023+111.9%Added
Novo Holdings A/S5,350,000$70.1M4.95%00.0%Unchanged
Janus Henderson Group PLC5,503,349$72.1M0.04%+221,195+4.2%Added
Paradigm Biocapital Advisors LP6,142,344$80.5M3.44%+1,747,788+39.8%Added
BlackRock, Inc.6,781,046$88.9M0.00%+296,038+4.6%Added
Baker Bros. Advisors LP7,305,940$95.8M0.93%+1,150,000+18.7%Added
Ra Capital Management, L.P.9,902,633$129.8M2.19%+993,542+11.2%Added
OrbiMed Advisors LLC15,518,492$203.4M5.12%+496,771+3.3%Added
Deep Track Capital, LP0$00.00%−1,400,000−100.0%Sold out
Viking Global Investors LPSuperinvestorViking Global Investors0$00.00%−490,035−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−390,000−100.0%Sold out
Readystate Asset Management LP0$00.00%−361,233−100.0%Sold out
Pictet Asset Management Holding SA0$00.00%−302,513−100.0%Sold out
Ikarian Capital, LLC0$00.00%−280,000−100.0%Sold out
Caption Management, LLC0$00.00%−204,500−100.0%Sold out
Amundi0$00.00%−308,633−100.0%Sold out
StemPoint Capital LP0$00.00%−180,255−100.0%Sold out
Jennison Associates LLC0$00.00%−128,746−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−120,910−100.0%Sold out
EFG Asset Management (North America) Corp.0$00.00%−104,386−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−102,650−100.0%Sold out
Acuta Capital Partners, LLC0$00.00%−85,454−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−85,214−100.0%Sold out
Bridger Management, LLC0$00.00%−74,700−100.0%Sold out
Squarepoint Ops LLC0$00.00%−45,756−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−36,049−100.0%Sold out
Two Sigma Investments, LP0$00.00%−34,999−100.0%Sold out
TD Asset Management Inc0$00.00%−33,200−100.0%Sold out
Fred Alger Management, LLC0$00.00%−27,635−100.0%Sold out