Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2026 年第 1 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2026/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 497
- 較 2025 年第 4 季 +8 家
- 持有股數
- 1.73 億
- 較 2025 年第 4 季 +1,914 萬 (+12.5%)
- 總市值
- $129.7 億
- 較 2025 年第 4 季 +$8.28 億 (+6.8%)
- 新進機構
- 73
- 另有 179 家加碼
- 清倉機構
- 65
- 另有 158 家減碼
另有 5 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2026 年第 1 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| LPL Financial LLC | 31,932 | $239.8 萬 | 0.00% | +863+2.8% | 加碼 |
| Swedbank AB | 32,253 | $242.2 萬 | 0.00% | +5,000+18.3% | 加碼 |
| Pathstone Holdings, LLC | 32,835 | $246.6 萬 | 0.01% | −1,469−4.3% | 減碼 |
| Toroso Investments, LLC | 34,432 | $251.2 萬 | 0.01% | +16,524+92.3% | 加碼 |
| Assenagon Asset Management S.A. | 33,673 | $252.9 萬 | 0.00% | +4,357+14.9% | 加碼 |
| Blair William & Co | 33,857 | $254.2 萬 | 0.01% | +69+0.2% | 加碼 |
| KLP Kapitalforvaltning AS | 33,900 | $254.6 萬 | 0.01% | +400+1.2% | 加碼 |
| Exchange Traded Concepts, LLC | 33,941 | $254.9 萬 | 0.02% | +12,847+60.9% | 加碼 |
| PEAK6 LLC | 34,419 | $258.5 萬 | 0.07% | +3,777+12.3% | 加碼 |
| Van Eck Associates Corp | 34,505 | $259.1 萬 | 0.00% | −12,597−26.7% | 減碼 |
| Raiffeisen Bank International AG | 36,000 | $261.1 萬 | 0.04% | +1,000+2.9% | 加碼 |
| BLB&B Advisors, LLC | 35,170 | $264.1 萬 | 0.11% | −26,350−42.8% | 減碼 |
| Prudential Financial Inc | 35,268 | $264.8 萬 | 0.00% | +11,260+46.9% | 加碼 |
| Grandfield & Dodd, LLC | 37,326 | $280.3 萬 | 0.16% | −495−1.3% | 減碼 |
| Intech Investment Management LLC | 38,515 | $289.2 萬 | 0.03% | +28,913+301.1% | 加碼 |
| Vanguard Investments Australia, Ltd. | 38,557 | $289.5 萬 | 0.01% | +38,557 | 新進 |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 38,988 | $292.8 萬 | 4.26% | +13,971+55.8% | 加碼 |
| Stanley-Laman Group, Ltd. | 39,306 | $295.1 萬 | 0.36% | +2,794+7.7% | 加碼 |
| Polygon Management Ltd. | 41,764 | $313.6 萬 | 0.62% | +41,764 | 新進 |
| Arizona State Retirement System | 42,266 | $317.4 萬 | 0.02% | −155−0.4% | 減碼 |
| Qube Research & Technologies Ltd | 42,856 | $321.8 萬 | 0.00% | +42,856 | 新進 |
| Guggenheim Capital LLC | 44,050 | $330.8 萬 | 0.03% | +6,341+16.8% | 加碼 |
| West Michigan Advisors, LLC | 44,614 | $335.0 萬 | 0.74% | +6,201+16.1% | 加碼 |
| Bamco Inc | 45,000 | $337.9 萬 | 0.01% | +9,000+25.0% | 加碼 |
| Ensign Peak Advisors, Inc | 46,004 | $345.4 萬 | 0.01% | −7,660−14.3% | 減碼 |
| Public Employees Retirement System of Ohio | 46,030 | $345.6 萬 | 0.01% | −1,568−3.3% | 減碼 |
| E Fund Management Co., Ltd. | 46,688 | $350.6 萬 | 0.10% | +46,688 | 新進 |
| Tudor Investment Corp Et Al | 48,244 | $362.3 萬 | 0.02% | +44,583+1,217.8% | 加碼 |
| Capital Counsel LLC | 49,580 | $372.3 萬 | 0.16% | −25−0.1% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 50,000 | $375.4 萬 | 0.01% | −90,000−64.3% | 減碼 |
| Nicola Wealth Management Ltd. | 52,000 | $390.5 萬 | 0.47% | −35,000−40.2% | 減碼 |
| Creative Planning | 52,228 | $392.2 萬 | 0.00% | −2,546−4.6% | 減碼 |
| State of New Jersey Common Pension Fund D | 52,588 | $394.9 萬 | 0.02% | −2,195−4.0% | 減碼 |
| Carmignac Gestion | 53,000 | $398.0 萬 | 0.06% | +53,000 | 新進 |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 54,269 | $407.5 萬 | 0.14% | −67,359−55.4% | 減碼 |
| Quantinno Capital Management LP | 55,502 | $416.8 萬 | 0.01% | +8,124+17.1% | 加碼 |
| DCF Advisers, LLC | 56,000 | $420.5 萬 | 1.59% | −47,000−45.6% | 減碼 |
| Panagora Asset Management Inc | 57,446 | $431.4 萬 | 0.02% | +57,446 | 新進 |
| Future Fund LLC | 58,732 | $441.0 萬 | 1.55% | +12,881+28.1% | 加碼 |
| One Capital Management, LLC | 58,939 | $442.6 萬 | 0.12% | +12,818+27.8% | 加碼 |
| Jefferies Financial Group Inc. | 59,065 | $443.5 萬 | 0.05% | +8,670+17.2% | 加碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 60,239 | $452.3 萬 | 0.01% | +11,318+23.1% | 加碼 |
| Rafferty Asset Management, LLC | 60,308 | $452.9 萬 | 0.02% | −13,675−18.5% | 減碼 |
| Polymer Capital Management (HK) LTD | 61,200 | $459.6 萬 | 0.64% | +61,200 | 新進 |
| Brinker Capital Investments, LLC | 61,344 | $460.6 萬 | 0.04% | +37,770+160.2% | 加碼 |
| Russell Investments Group, Ltd. | 62,919 | $472.5 萬 | 0.01% | +19,007+43.3% | 加碼 |
| SG Americas Securities, LLC | 63,295 | $475.3 萬 | 0.01% | +29,886+89.5% | 加碼 |
| Walleye Capital LLC | 65,949 | $495.2 萬 | 0.03% | +65,624+20,192.0% | 加碼 |
| Police & Firemen's Retirement System of New Jersey | 67,323 | $505.5 萬 | 0.04% | +474+0.7% | 加碼 |
| Treasurer of the State of North Carolina | 67,701 | $508.4 萬 | 0.02% | +1,439+2.2% | 加碼 |
| Janus Henderson Group PLC | 68,191 | $512.1 萬 | 0.00% | 00.0% | 不變 |
| Edgestream Partners, L.P. | 68,369 | $513.4 萬 | 0.17% | +68,369 | 新進 |
| Voya Investment Management LLC | 69,136 | $519.1 萬 | 0.01% | −4,624−6.3% | 減碼 |
| Erste Asset Management GmbH | 71,800 | $520.7 萬 | 0.05% | 00.0% | 不變 |
| Hillsdale Investment Management Inc. | 70,900 | $532.4 萬 | 0.14% | 00.0% | 不變 |
| Vanguard Global Advisers, LLC | 71,911 | $540.0 萬 | 0.00% | +71,911 | 新進 |
| Lisanti Capital Growth, LLC | 75,699 | $568.4 萬 | 1.43% | +42,910+130.9% | 加碼 |
| Boothbay Fund Management, LLC | 76,571 | $575.0 萬 | 0.14% | +1,009+1.3% | 加碼 |
| China Universal Asset Management Co., Ltd. | 77,315 | $580.6 萬 | 0.44% | +34,921+82.4% | 加碼 |
| CSS LLC | 79,093 | $593.9 萬 | 0.33% | +79,093 | 新進 |
| XTX Topco Ltd | 80,519 | $604.6 萬 | 0.11% | +63,602+376.0% | 加碼 |
| Nikko Asset Management Americas, Inc. | 81,696 | $613.4 萬 | 0.09% | −11,875−12.7% | 減碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 81,876 | $614.8 萬 | 0.00% | −11,875−12.7% | 減碼 |
| DekaBank Deutsche Girozentrale | 93,807 | $691.9 萬 | 0.01% | 00.0% | 不變 |
| Rhenman & Partners Asset Management AB | 92,900 | $697.6 萬 | 0.86% | −65,600−41.4% | 減碼 |
| Envestnet Asset Management Inc | 93,382 | $701.2 萬 | 0.00% | +3,463+3.9% | 加碼 |
| EFG International AG | 93,980 | $705.7 萬 | 0.15% | +18,704+24.8% | 加碼 |
| Marshall Wace, LLP | 95,954 | $720.5 萬 | 0.01% | −160,979−62.7% | 減碼 |
| Susquehanna Portfolio Strategies, LLC | 95,960 | $720.6 萬 | 0.11% | 00.0% | 不變 |
| State of Wisconsin Investment Board | 96,491 | $724.6 萬 | 0.02% | +1,730+1.8% | 加碼 |
| Gotham Asset Management, LLC | 98,968 | $743.2 萬 | 0.02% | +55,756+129.0% | 加碼 |
| Empowered Funds, LLC | 103,141 | $774.5 萬 | 0.05% | +103,141 | 新進 |
| Winton Group Ltd | 106,532 | $799.9 萬 | 0.28% | +106,532 | 新進 |
| Victory Capital Management Inc | 108,744 | $816.6 萬 | 0.01% | +28,015+34.7% | 加碼 |
| Exome Asset Management LLC | 110,064 | $826.5 萬 | 4.86% | −6,451−5.5% | 減碼 |
| Kennedy Capital Management, Inc. | 111,830 | $839.7 萬 | 0.18% | +2,539+2.3% | 加碼 |
| Standard Life Aberdeen plc | 113,843 | $854.8 萬 | 0.01% | +84,917+293.6% | 加碼 |
| Nomura Holdings Inc | 114,080 | $856.6 萬 | 0.07% | −734,735−86.6% | 減碼 |
| SEB Asset Management AB | 114,334 | $858.5 萬 | 0.04% | +114,334 | 新進 |
| Algert Global LLC | 116,563 | $875.3 萬 | 0.13% | −10,642−8.4% | 減碼 |
| Great Lakes Advisors, LLC | 118,926 | $893.0 萬 | 0.07% | −30,254−20.3% | 減碼 |
| Integral Health Asset Management, LLC | 125,000 | $938.6 萬 | 0.50% | +125,000 | 新進 |
| HealthInvest Partners AB | 27,873 | $939.9 萬 | 3.03% | −64,504−69.8% | 減碼 |
| Ikarian Capital, LLC | 127,038 | $953.9 萬 | 1.36% | −75,000−37.1% | 減碼 |
| Braidwell LP | 130,862 | $982.6 萬 | 0.33% | +130,862 | 新進 |
| Engineers Gate Manager LP | 133,827 | $1,005 萬 | 0.13% | +111,636+503.1% | 加碼 |
| State Board of Administration of Florida Retirement System | 135,878 | $1,020 萬 | 0.02% | 00.0% | 不變 |
| Edmond de Rothschild Holding S.A. | 137,190 | $1,030 萬 | 0.15% | +15,000+12.3% | 加碼 |
| Vanguard Asset Management, Ltd | 137,507 | $1,033 萬 | 0.01% | +137,507 | 新進 |
| Fisher Asset Management, LLC | 141,544 | $1,063 萬 | 0.00% | −71−0.1% | 減碼 |
| Capital Fund Management S.A. | 142,201 | $1,068 萬 | 0.10% | +142,201 | 新進 |
| Artia Global Partners LP | 144,376 | $1,084 萬 | 2.44% | 00.0% | 不變 |
| Citigroup Inc | 146,541 | $1,100 萬 | 0.01% | +57,201+64.0% | 加碼 |
| Aquatic Capital Management LLC | 147,379 | $1,107 萬 | 0.32% | +14,553+11.0% | 加碼 |
| Manufacturers Life Insurance Company, The | 149,538 | $1,123 萬 | 0.01% | −3,703−2.4% | 減碼 |
| CenterBook Partners LP | 150,912 | $1,133 萬 | 0.61% | −3,037−2.0% | 減碼 |
| SEI Investments Co | 157,222 | $1,181 萬 | 0.01% | +41,305+35.6% | 加碼 |
| Sicart Associates LLC | 159,412 | $1,197 萬 | 3.07% | −4,145−2.5% | 減碼 |
| Deutsche Bank AG | 159,891 | $1,201 萬 | 0.00% | +10,448+7.0% | 加碼 |
| ADAR1 Capital Management, LLC | 160,338 | $1,204 萬 | 0.72% | +13,208+9.0% | 加碼 |