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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Zymeworks Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
212
+4 vs. Q4 2025
Shares held
70.3M
+1.16M (+1.7%) vs. Q4 2025
Total value
$1.76B
−$60.1M (−3.3%) vs. Q4 2025
New holders
40
77 more added
Sold out
36
58 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 212 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ1 2026: $1.76B
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2025.

Institutions holding ZYME in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Engineers Gate Manager LP31,548$790.0K0.01%+31,548New
SBI Okasan Asset Management Co.Ltd.32,000$774.7K0.03%00.0%Unchanged
Universal- Beteiligungs- und Servicegesellschaft mbH30,432$762.0K0.00%−2,383−7.3%Reduced
STRS Ohio30,100$753.7K0.00%+3,500+13.2%Added
MetLife Investment Management29,653$742.5K0.00%+1,023+3.6%Added
Journey Strategic Wealth LLC29,050$727.4K0.02%00.0%Unchanged
BNP Paribas Arbitrage, SA28,119$704.1K0.00%+4,821+20.7%Added
Oxford Asset Management LLP27,812$696.4K0.28%+27,812New
Schroder Investment Management Group28,349$686.3K0.00%−69,558−71.0%Reduced
ExodusPoint Capital Management, LP27,374$685.4K0.01%+27,374New
Massachusetts Financial Services Co27,354$684.9K0.00%−729−2.6%Reduced
Vanguard Asset Management, Ltd26,279$658.0K0.00%+26,279New
Legal & General Group Plc26,209$656.3K0.00%−5,940−18.5%Reduced
Commonwealth Equity Services, LLC26,031$651.8K0.00%−64−0.2%Reduced
Susquehanna International Group, LLP24,421$611.5K0.00%−151,667−86.1%Reduced
Ritholtz Wealth Management24,243$607.0K0.01%−95−0.4%Reduced
Mirae Asset Global ETFs Holdings Ltd.23,373$585.3K0.00%+264+1.1%Added
Headlands Technologies LLC22,845$572.0K0.07%+22,845New
Duncan Williams Asset Management, LLC22,095$553.3K0.15%00.0%Unchanged
Prudential Financial Inc21,970$550.1K0.00%+9,215+72.2%Added
Gsa Capital Partners LLP20,511$514.0K0.03%+20,511New
Jackson Creek Investment Advisors LLC18,695$468.0K0.14%+18,695New
Barclays PLC18,374$460.1K0.00%−61,592−77.0%Reduced
Janus Henderson Group PLC18,200$455.8K0.00%00.0%Unchanged
Bank of Montreal17,468$437.4K0.00%00.0%Unchanged
New York State Common Retirement Fund17,371$435.0K0.00%00.0%Unchanged
State of Wyoming17,148$429.4K0.05%+6,273+57.7%Added
Quadrature Capital Ltd16,735$419.0K0.00%−6,282−27.3%Reduced
State Board of Administration of Florida Retirement System15,340$384.1K0.00%00.0%Unchanged
Agf Management Ltd15,000$375.6K0.00%00.0%Unchanged
Amundi14,084$352.7K0.00%+14,084New
Police & Firemen's Retirement System of New Jersey13,702$343.1K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.13,280$332.5K0.03%+1,085+8.9%Added
Freestone Grove Partners LP12,945$324.1K0.00%+12,945New
State of New Jersey Common Pension Fund D12,788$320.2K0.00%+12,788New
Northwest & Ethical Investments L.P.12,244$316.4K0.01%+200+1.7%Added
Intech Investment Management LLC12,541$314.0K0.00%−7,789−38.3%Reduced
Virginia Retirement Systems Et Al11,935$298.9K0.00%−16,000−57.3%Reduced
Abacus Wealth Partners, LLC11,669$292.2K0.03%+1,447+14.2%Added
Janney Montgomery Scott LLC11,487$288.0K0.00%+420+3.8%Added
James Investment Research Inc10,925$273.6K0.03%00.0%Unchanged
Ewing Morris & Co. Investment Partners Ltd.10,850$271.7K0.12%00.0%Unchanged
Virtus Investment Advisers, Inc.10,702$268.0K0.07%+261+2.5%Added
Lazard Asset Management LLC10,602$265.5K0.00%−3,174−23.0%Reduced
ProShare Advisors LLC10,574$264.8K0.00%−1,813−14.6%Reduced
SG Americas Securities, LLC10,429$261.0K0.00%−7,128−40.6%Reduced
Arizona State Retirement System10,277$257.3K0.00%−118−1.1%Reduced
Soleus Capital Management, L.P.10,000$250.4K0.01%−90,000−90.0%Reduced
PSP Research LLC10,000$250.4K0.18%−10,312−50.8%Reduced
Pictet Asset Management Holding SA9,256$231.8K0.00%−64,371−87.4%Reduced
Voya Investment Management LLC8,993$225.2K0.00%−241−2.6%Reduced
Allspring Global Investments Holdings, LLC8,507$220.7K0.00%+800+10.4%Added
Vanguard Investments Australia, Ltd.8,803$220.4K0.00%+8,803New
Winton Group Ltd8,400$210.3K0.01%−2,780−24.9%Reduced
Cygnus Capital Advisors, LLC8,197$205.0K0.14%+2,200+36.7%Added
KLP Kapitalforvaltning AS8,000$200.3K0.00%00.0%Unchanged
CWM, LLC6,955$174.2K0.00%−20−0.3%Reduced
Vanguard Global Advisers, LLC5,459$136.7K0.00%+5,459New
Tower Research Capital LLC (TRC)4,868$121.9K0.00%+3,515+259.8%Added
Ameritas Investment Partners, Inc.4,164$104.3K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.3,903$97.7K0.00%+266+7.3%Added
DekaBank Deutsche Girozentrale3,843$96.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,681$42.1K0.00%+211+14.4%Added
Global Wealth Strategies & Associates1,635$40.9K0.01%+1,635New
Sofinnova Investments, Inc.1,610$40.3K0.00%+1,610New
TD Waterhouse Canada Inc.1,439$37.2K0.00%+1,128+362.7%Added
Simplex Trading, LLC1,336$33.5K0.00%−46,704−97.2%Reduced
Aviso Financial Inc.1,146$28.7K0.00%+1,146New
GAMMA Investing LLC1,097$27.5K0.00%+112+11.4%Added
The PNC Financial Services Group, Inc.987$24.7K0.00%+206+26.4%Added
Nisa Investment Advisors, LLC971$24.3K0.00%+3+0.3%Added
Steward Partners Investment Advisory, LLC971$24.3K0.00%+918+1,732.1%Added
Optiver Holding B.V.958$24.0K0.00%−190−16.6%Reduced
Advisor Group Holdings, Inc.882$22.1K0.00%−1,628−64.9%Reduced
NBC Securities, Inc.623$15.6K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec570$14.3K0.00%00.0%Unchanged
National Bank of Canada554$13.9K0.00%+9+1.7%Added
Umb Bank N A466$11.7K0.00%00.0%Unchanged
Jones Financial Companies LLLP465$11.2K0.00%+445+2,225.0%Added
US Bancorp352$8.81K0.00%+65+22.6%Added
Parallel Advisors, LLC352$8.81K0.00%+23+7.0%Added
Huntington National Bank343$8.59K0.00%−21−5.8%Reduced
Sterling Capital Management LLC324$8.11K0.00%−7−2.1%Reduced
EverSource Wealth Advisors, LLC218$5.46K0.00%+36+19.8%Added
Caitong International Asset Management Co., Ltd216$5.41K0.00%−1,183−84.6%Reduced
Allworth Financial LP109$2.73K0.00%−37−25.3%Reduced
IFP Advisors, Inc96$2.40K0.00%00.0%Unchanged
HighMark Wealth Management LLC80$2.00K0.00%−150−65.2%Reduced
Rothschild Investment LLC80$2.00K0.00%+24+42.9%Added
Walleye Capital LLC78$1.95K0.00%−13,589−99.4%Reduced
Signaturefd, LLC77$1.93K0.00%+35+83.3%Added
Fifth Third Bancorp67$1.68K0.00%+67New
Kilter Group LLC66$1.65K0.00%00.0%Unchanged
Bare Financial Services, Inc64$1.60K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.61$1.53K0.00%+61New
Farther Finance Advisors, LLC57$1.48K0.00%−222−79.6%Reduced
True Wealth Design, LLC58$1.45K0.00%00.0%Unchanged
UMA Financial Services, Inc.51$1.28K0.00%00.0%Unchanged
Versant Capital Management, Inc45$1.13K0.00%+45New
Covestor Ltd28$1.00K0.00%−26−48.1%Reduced