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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Zymeworks Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
212
+4 vs. Q4 2025
Shares held
70.3M
+1.16M (+1.7%) vs. Q4 2025
Total value
$1.76B
−$60.1M (−3.3%) vs. Q4 2025
New holders
40
77 more added
Sold out
36
58 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 212 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ1 2026: $1.76B
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2025.

Institutions holding ZYME in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Hughes Financial Services, LLC4$1000.00%+4New
Larson Financial Group LLC6$1500.00%00.0%Unchanged
MAI Capital Management7$1760.00%+2+40.0%Added
SBI Securities Co., Ltd.11$2750.00%00.0%Unchanged
Smartleaf Asset Management LLC12$2910.00%00.0%Unchanged
Essential Partners LLC12$3000.00%00.0%Unchanged
Root Financial Partners, LLC12$3000.00%+12New
CoreCap Advisors, LLC18$4510.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd42$5000.00%+42New
Twin Peaks Wealth Advisors, LLC20$5010.00%+20New
International Assets Investment Management, LLC25$6490.00%00.0%Unchanged
Sunbelt Securities, Inc.27$6760.00%00.0%Unchanged
Covestor Ltd28$1.00K0.00%−26−48.1%Reduced
Versant Capital Management, Inc45$1.13K0.00%+45New
UMA Financial Services, Inc.51$1.28K0.00%00.0%Unchanged
True Wealth Design, LLC58$1.45K0.00%00.0%Unchanged
Farther Finance Advisors, LLC57$1.48K0.00%−222−79.6%Reduced
Rockefeller Capital Management L.P.61$1.53K0.00%+61New
Bare Financial Services, Inc64$1.60K0.00%00.0%Unchanged
Kilter Group LLC66$1.65K0.00%00.0%Unchanged
Fifth Third Bancorp67$1.68K0.00%+67New
Signaturefd, LLC77$1.93K0.00%+35+83.3%Added
Walleye Capital LLC78$1.95K0.00%−13,589−99.4%Reduced
HighMark Wealth Management LLC80$2.00K0.00%−150−65.2%Reduced
Rothschild Investment LLC80$2.00K0.00%+24+42.9%Added
IFP Advisors, Inc96$2.40K0.00%00.0%Unchanged
Allworth Financial LP109$2.73K0.00%−37−25.3%Reduced
Caitong International Asset Management Co., Ltd216$5.41K0.00%−1,183−84.6%Reduced
EverSource Wealth Advisors, LLC218$5.46K0.00%+36+19.8%Added
Sterling Capital Management LLC324$8.11K0.00%−7−2.1%Reduced
Huntington National Bank343$8.59K0.00%−21−5.8%Reduced
Parallel Advisors, LLC352$8.81K0.00%+23+7.0%Added
US Bancorp352$8.81K0.00%+65+22.6%Added
Jones Financial Companies LLLP465$11.2K0.00%+445+2,225.0%Added
Umb Bank N A466$11.7K0.00%00.0%Unchanged
National Bank of Canada554$13.9K0.00%+9+1.7%Added
Federation des caisses Desjardins du Quebec570$14.3K0.00%00.0%Unchanged
NBC Securities, Inc.623$15.6K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.882$22.1K0.00%−1,628−64.9%Reduced
Optiver Holding B.V.958$24.0K0.00%−190−16.6%Reduced
Nisa Investment Advisors, LLC971$24.3K0.00%+3+0.3%Added
Steward Partners Investment Advisory, LLC971$24.3K0.00%+918+1,732.1%Added
The PNC Financial Services Group, Inc.987$24.7K0.00%+206+26.4%Added
GAMMA Investing LLC1,097$27.5K0.00%+112+11.4%Added
Aviso Financial Inc.1,146$28.7K0.00%+1,146New
Simplex Trading, LLC1,336$33.5K0.00%−46,704−97.2%Reduced
TD Waterhouse Canada Inc.1,439$37.2K0.00%+1,128+362.7%Added
Sofinnova Investments, Inc.1,610$40.3K0.00%+1,610New
Global Wealth Strategies & Associates1,635$40.9K0.01%+1,635New
GF Fund Management Co. Ltd.1,681$42.1K0.00%+211+14.4%Added
DekaBank Deutsche Girozentrale3,843$96.0K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.3,903$97.7K0.00%+266+7.3%Added
Ameritas Investment Partners, Inc.4,164$104.3K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)4,868$121.9K0.00%+3,515+259.8%Added
Vanguard Global Advisers, LLC5,459$136.7K0.00%+5,459New
CWM, LLC6,955$174.2K0.00%−20−0.3%Reduced
KLP Kapitalforvaltning AS8,000$200.3K0.00%00.0%Unchanged
Cygnus Capital Advisors, LLC8,197$205.0K0.14%+2,200+36.7%Added
Winton Group Ltd8,400$210.3K0.01%−2,780−24.9%Reduced
Vanguard Investments Australia, Ltd.8,803$220.4K0.00%+8,803New
Allspring Global Investments Holdings, LLC8,507$220.7K0.00%+800+10.4%Added
Voya Investment Management LLC8,993$225.2K0.00%−241−2.6%Reduced
Pictet Asset Management Holding SA9,256$231.8K0.00%−64,371−87.4%Reduced
Soleus Capital Management, L.P.10,000$250.4K0.01%−90,000−90.0%Reduced
PSP Research LLC10,000$250.4K0.18%−10,312−50.8%Reduced
Arizona State Retirement System10,277$257.3K0.00%−118−1.1%Reduced
SG Americas Securities, LLC10,429$261.0K0.00%−7,128−40.6%Reduced
ProShare Advisors LLC10,574$264.8K0.00%−1,813−14.6%Reduced
Lazard Asset Management LLC10,602$265.5K0.00%−3,174−23.0%Reduced
Virtus Investment Advisers, Inc.10,702$268.0K0.07%+261+2.5%Added
Ewing Morris & Co. Investment Partners Ltd.10,850$271.7K0.12%00.0%Unchanged
James Investment Research Inc10,925$273.6K0.03%00.0%Unchanged
Janney Montgomery Scott LLC11,487$288.0K0.00%+420+3.8%Added
Abacus Wealth Partners, LLC11,669$292.2K0.03%+1,447+14.2%Added
Virginia Retirement Systems Et Al11,935$298.9K0.00%−16,000−57.3%Reduced
Intech Investment Management LLC12,541$314.0K0.00%−7,789−38.3%Reduced
Northwest & Ethical Investments L.P.12,244$316.4K0.01%+200+1.7%Added
State of New Jersey Common Pension Fund D12,788$320.2K0.00%+12,788New
Freestone Grove Partners LP12,945$324.1K0.00%+12,945New
China Universal Asset Management Co., Ltd.13,280$332.5K0.03%+1,085+8.9%Added
Police & Firemen's Retirement System of New Jersey13,702$343.1K0.00%00.0%Unchanged
Amundi14,084$352.7K0.00%+14,084New
Agf Management Ltd15,000$375.6K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System15,340$384.1K0.00%00.0%Unchanged
Quadrature Capital Ltd16,735$419.0K0.00%−6,282−27.3%Reduced
State of Wyoming17,148$429.4K0.05%+6,273+57.7%Added
New York State Common Retirement Fund17,371$435.0K0.00%00.0%Unchanged
Bank of Montreal17,468$437.4K0.00%00.0%Unchanged
Janus Henderson Group PLC18,200$455.8K0.00%00.0%Unchanged
Barclays PLC18,374$460.1K0.00%−61,592−77.0%Reduced
Jackson Creek Investment Advisors LLC18,695$468.0K0.14%+18,695New
Gsa Capital Partners LLP20,511$514.0K0.03%+20,511New
Prudential Financial Inc21,970$550.1K0.00%+9,215+72.2%Added
Duncan Williams Asset Management, LLC22,095$553.3K0.15%00.0%Unchanged
Headlands Technologies LLC22,845$572.0K0.07%+22,845New
Mirae Asset Global ETFs Holdings Ltd.23,373$585.3K0.00%+264+1.1%Added
Ritholtz Wealth Management24,243$607.0K0.01%−95−0.4%Reduced
Susquehanna International Group, LLP24,421$611.5K0.00%−151,667−86.1%Reduced
Commonwealth Equity Services, LLC26,031$651.8K0.00%−64−0.2%Reduced
Legal & General Group Plc26,209$656.3K0.00%−5,940−18.5%Reduced