Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Zymeworks Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 212
- +4 vs. Q4 2025
- Shares held
- 70.3M
- +1.16M (+1.7%) vs. Q4 2025
- Total value
- $1.76B
- −$60.1M (−3.3%) vs. Q4 2025
- New holders
- 40
- 77 more added
- Sold out
- 36
- 58 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Asset Management, Ltd | 26,279 | $658.0K | 0.00% | +26,279 | New |
| Massachusetts Financial Services Co | 27,354 | $684.9K | 0.00% | −729−2.6% | Reduced |
| ExodusPoint Capital Management, LP | 27,374 | $685.4K | 0.01% | +27,374 | New |
| Schroder Investment Management Group | 28,349 | $686.3K | 0.00% | −69,558−71.0% | Reduced |
| Oxford Asset Management LLP | 27,812 | $696.4K | 0.28% | +27,812 | New |
| BNP Paribas Arbitrage, SA | 28,119 | $704.1K | 0.00% | +4,821+20.7% | Added |
| Journey Strategic Wealth LLC | 29,050 | $727.4K | 0.02% | 00.0% | Unchanged |
| MetLife Investment Management | 29,653 | $742.5K | 0.00% | +1,023+3.6% | Added |
| STRS Ohio | 30,100 | $753.7K | 0.00% | +3,500+13.2% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 30,432 | $762.0K | 0.00% | −2,383−7.3% | Reduced |
| SBI Okasan Asset Management Co.Ltd. | 32,000 | $774.7K | 0.03% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 31,548 | $790.0K | 0.01% | +31,548 | New |
| Manufacturers Life Insurance Company, The | 31,592 | $791.1K | 0.00% | +14,159+81.2% | Added |
| Marshall Wace, LLP | 32,223 | $806.9K | 0.00% | +32,223 | New |
| Creative Planning | 32,394 | $811.1K | 0.00% | +4,101+14.5% | Added |
| Martingale Asset Management L P | 32,764 | $820.4K | 0.02% | +32,764 | New |
| Vinva Investment Management Ltd | 24,090 | $850.8K | 0.01% | +11,874+97.2% | Added |
| HighVista Strategies LLC | 34,085 | $853.5K | 0.24% | +34,085 | New |
| Price T Rowe Associates Inc | 35,487 | $889.0K | 0.00% | +6,703+23.3% | Added |
| Persistent Asset Partners Ltd | 35,935 | $899.8K | 0.35% | +28,589+389.2% | Added |
| HighTower Advisors, LLC | 36,262 | $908.0K | 0.00% | +36,262 | New |
| Tudor Investment Corp Et Al | 36,875 | $923.4K | 0.00% | +6,551+21.6% | Added |
| O'Shaughnessy Asset Management, LLC | 37,129 | $929.7K | 0.00% | −5,923−13.8% | Reduced |
| California State Teachers Retirement System | 37,389 | $936.2K | 0.00% | −372−1.0% | Reduced |
| HSBC Holdings PLC | 37,777 | $940.1K | 0.00% | +19,909+111.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 37,919 | $949.5K | 0.00% | +37,919 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 39,355 | $985.4K | 0.00% | +18,934+92.7% | Added |
| Quantinno Capital Management LP | 39,640 | $992.6K | 0.00% | +10,757+37.2% | Added |
| Los Angeles Capital Management LLC | 39,750 | $995.3K | 0.00% | +39,363+10,171.3% | Added |
| Manatuck Hill Partners, LLC | 40,000 | $1.00M | 0.33% | +40,000 | New |
| Envestnet Asset Management Inc | 40,419 | $1.01M | 0.00% | −393−1.0% | Reduced |
| Victory Capital Management Inc | 42,404 | $1.06M | 0.00% | −501−1.2% | Reduced |
| Jacobs Levy Equity Management, Inc | 42,786 | $1.07M | 0.00% | +42,786 | New |
| North Growth Management Ltd. | 46,000 | $1.14M | 0.17% | +1,000+2.2% | Added |
| Segall Bryant & Hamill, LLC | 45,726 | $1.14M | 0.02% | +45,726 | New |
| Royal Bank of Canada | 47,360 | $1.19M | 0.00% | −7,695−14.0% | Reduced |
| Russell Investments Group, Ltd. | 47,450 | $1.19M | 0.00% | −10,900−18.7% | Reduced |
| Campbell & CO Investment Adviser LLC | 54,883 | $1.37M | 0.08% | +21,295+63.4% | Added |
| Dana Investment Advisors, Inc. | 56,107 | $1.40M | 0.04% | +7,789+16.1% | Added |
| Alliancebernstein L.P. | 55,896 | $1.47M | 0.00% | +5,866+11.7% | Added |
| State of Wisconsin Investment Board | 66,106 | $1.66M | 0.00% | −9,460−12.5% | Reduced |
| American Century Companies Inc | 70,851 | $1.77M | 0.00% | +12,019+20.4% | Added |
| Swiss National Bank | 74,200 | $1.86M | 0.00% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 74,222 | $1.86M | 0.00% | −38,919−34.4% | Reduced |
| Credit Agricole S A | 75,000 | $1.88M | 0.01% | 00.0% | Unchanged |
| Rhumbline Advisers | 75,399 | $1.89M | 0.00% | −99−0.1% | Reduced |
| Stifel Financial Corp | 76,756 | $1.92M | 0.00% | +909+1.2% | Added |
| Franklin Resources Inc | 77,659 | $1.94M | 0.00% | +18,672+31.7% | Added |
| Principal Financial Group Inc | 78,547 | $1.97M | 0.00% | +78,547 | New |
| Verdad Advisers, LP | 82,698 | $2.07M | 2.33% | +82,698 | New |
| Mackenzie Financial Corp | 82,726 | $2.07M | 0.00% | +37,266+82.0% | Added |
| Squarepoint Ops LLC | 83,146 | $2.08M | 0.00% | +83,146 | New |
| Vanguard Fiduciary Trust Co | 84,403 | $2.11M | 0.00% | +84,403 | New |
| Kornitzer Capital Management Inc | 88,800 | $2.22M | 0.05% | 00.0% | Unchanged |
| AQR Capital Management LLC | 90,669 | $2.27M | 0.00% | −406−0.4% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 99,795 | $2.50M | 0.04% | 00.0% | Unchanged |
| Fisher Asset Management, LLC | 101,439 | $2.54M | 0.00% | +33,242+48.7% | Added |
| Tema ETFs LLC | 104,931 | $2.63M | 0.18% | +28,956+38.1% | Added |
| Toroso Investments, LLC | 104,931 | $2.63M | 0.01% | +104,931 | New |
| Platinum Investment Management Ltd | 105,184 | $2.63M | 0.66% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 114,072 | $2.76M | 0.00% | +79,064+225.8% | Added |
| Citigroup Inc | 114,327 | $2.86M | 0.00% | +3,120+2.8% | Added |
| Bank of New York Mellon Corp | 124,105 | $3.11M | 0.00% | −4,026−3.1% | Reduced |
| Invesco Ltd. | 125,630 | $3.15M | 0.00% | −131,950−51.2% | Reduced |
| Wellington Management Group LLP | 138,690 | $3.47M | 0.00% | −43,015−23.7% | Reduced |
| Diadema Partners LP | 142,132 | $3.56M | 1.47% | +142,132 | New |
| XTX Topco Ltd | 143,882 | $3.60M | 0.06% | +50,413+53.9% | Added |
| Kennedy Capital Management, Inc. | 148,226 | $3.71M | 0.08% | +2,692+1.8% | Added |
| Silvercrest Asset Management Group LLC | 163,649 | $4.10M | 0.03% | −18,141−10.0% | Reduced |
| UBS Group AG | 171,779 | $4.30M | 0.00% | −107,075−38.4% | Reduced |
| Raymond James Financial Inc | 176,411 | $4.42M | 0.00% | −11,274−6.0% | Reduced |
| Federated Hermes, Inc. | 182,410 | $4.57M | 0.01% | +29,721+19.5% | Added |
| Charles Schwab Investment Management Inc | 185,124 | $4.64M | 0.00% | −35,785−16.2% | Reduced |
| Wells Fargo & Company | 189,636 | $4.75M | 0.00% | −18,677−9.0% | Reduced |
| Man Group plc | 189,890 | $4.75M | 0.01% | +114,572+152.1% | Added |
| Panagora Asset Management Inc | 206,854 | $5.18M | 0.02% | +128,518+164.1% | Added |
| Jane Street Group, LLC | 226,967 | $5.68M | 0.01% | +156,522+222.2% | Added |
| D. E. Shaw & Co., Inc. | 235,621 | $5.90M | 0.00% | +11,835+5.3% | Added |
| Bank of America Corp | 236,754 | $5.93M | 0.00% | +147,230+164.5% | Added |
| HRT Financial LP | 237,889 | $5.96M | 0.01% | +116,825+96.5% | Added |
| Granahan Investment Management Inc | 250,773 | $6.28M | 0.30% | +26,365+11.7% | Added |
| Picton Mahoney Asset Management | 256,690 | $6.43M | 0.07% | +11,892+4.9% | Added |
| Royce & Associates LP | 299,202 | $7.49M | 0.07% | +299,202 | New |
| UBS Asset Management Americas Inc | 319,385 | $8.00M | 0.00% | −876−0.3% | Reduced |
| Northern Trust Corp | 320,210 | $8.02M | 0.00% | +12,231+4.0% | Added |
| SummitTX Capital, L.P. | 321,427 | $8.05M | 0.26% | +97,159+43.3% | Added |
| Hillsdale Investment Management Inc. | 345,622 | $8.65M | 0.24% | +107,700+45.3% | Added |
| Redmile Group, LLC | 491,654 | $12.3M | 0.82% | 00.0% | Unchanged |
| Vanguard Portfolio Management LLC | 499,875 | $12.5M | 0.00% | +499,875 | New |
| Qube Research & Technologies Ltd | 511,937 | $12.8M | 0.02% | +37,647+7.9% | Added |
| Prosight Management, LP | 539,049 | $13.5M | 2.21% | +8,656+1.6% | Added |
| MPM Oncology Impact Management LP | 565,249 | $14.2M | 1.09% | +565,249 | New |
| Goldman Sachs Group Inc | 599,486 | $15.0M | 0.00% | +179,279+42.7% | Added |
| Nuveen, LLC | 651,662 | $16.3M | 0.00% | +3,336+0.5% | Added |
| Geode Capital Management, LLC | 659,940 | $16.5M | 0.00% | +11,970+1.8% | Added |
| FMR LLC | 667,153 | $16.7M | 0.00% | +107,067+19.1% | Added |
| Assenagon Asset Management S.A. | 727,986 | $18.2M | 0.03% | +80,612+12.5% | Added |
| Arrowstreet Capital, Limited Partnership | 743,898 | $18.6M | 0.01% | +43,896+6.3% | Added |
| Deutsche Bank AG | 921,250 | $23.1M | 0.01% | −674,583−42.3% | Reduced |
| Capricorn Fund Managers Ltd | 1,007,210 | $25.2M | 3.93% | −15,630−1.5% | Reduced |