Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Zymeworks Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 184
- +3 vs. Q2 2025
- Shares held
- 73.7M
- −1.71M (−2.3%) vs. Q2 2025
- Total value
- $1.26B
- +$312.6M (+33.0%) vs. Q2 2025
- New holders
- 25
- 61 more added
- Sold out
- 22
- 65 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Massachusetts Financial Services Co | 29,015 | $495.6K | 0.00% | +1,906+7.0% | Added |
| Simplex Trading, LLC | 28,761 | $491.0K | 0.01% | +22,316+346.3% | Added |
| Legal & General Group Plc | 28,369 | $484.5K | 0.00% | −15,394−35.2% | Reduced |
| Bank of Montreal | 27,642 | $472.1K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 27,314 | $466.5K | 0.00% | +1,925+7.6% | Added |
| Price T Rowe Associates Inc | 26,816 | $459.0K | 0.00% | 00.0% | Unchanged |
| Ritholtz Wealth Management | 24,722 | $422.3K | 0.01% | −513−2.0% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 22,945 | $391.9K | 0.00% | −3,918−14.6% | Reduced |
| Vinva Investment Management Ltd | 14,594 | $382.4K | 0.01% | +14,594 | New |
| Duncan Williams Asset Management, LLC | 22,095 | $377.4K | 0.11% | 00.0% | Unchanged |
| DLD Asset Management, LP | 20,000 | $341.6K | 0.04% | +20,000 | New |
| Janus Henderson Group PLC | 18,200 | $311.0K | 0.00% | 00.0% | Unchanged |
| PharVision Advisers, LLC | 17,790 | $303.9K | 0.17% | +17,790 | New |
| Manufacturers Life Insurance Company, The | 17,574 | $300.2K | 0.00% | −1,496−7.8% | Reduced |
| Intech Investment Management LLC | 16,982 | $290.1K | 0.00% | −6,181−26.7% | Reduced |
| Fox Run Management, L.L.C. | 16,145 | $275.8K | 0.04% | +16,145 | New |
| BNP Paribas Arbitrage, SA | 15,460 | $264.1K | 0.00% | +5,153+50.0% | Added |
| State Board of Administration of Florida Retirement System | 15,340 | $262.0K | 0.00% | 00.0% | Unchanged |
| Lazard Asset Management LLC | 15,308 | $261.5K | 0.00% | +15,308 | New |
| Envestnet Asset Management Inc | 14,574 | $248.9K | 0.00% | −32−0.2% | Reduced |
| Brevan Howard Capital Management LP | 14,518 | $248.0K | 0.00% | +3,890+36.6% | Added |
| Police & Firemen's Retirement System of New Jersey | 14,205 | $242.6K | 0.00% | +2,536+21.7% | Added |
| SG Americas Securities, LLC | 13,624 | $233.0K | 0.00% | +4,953+57.1% | Added |
| New York State Common Retirement Fund | 13,371 | $228.4K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 13,176 | $225.0K | 0.02% | −820−5.9% | Reduced |
| Two Sigma Securities, LLC | 12,225 | $208.8K | 0.03% | +12,225 | New |
| Tower Research Capital LLC (TRC) | 11,301 | $193.0K | 0.01% | +6,354+128.4% | Added |
| ProShare Advisors LLC | 11,201 | $191.3K | 0.00% | −1,464−11.6% | Reduced |
| Janney Montgomery Scott LLC | 11,067 | $189.0K | 0.00% | −500−4.3% | Reduced |
| Arizona State Retirement System | 11,059 | $188.9K | 0.00% | −100−0.9% | Reduced |
| Ewing Morris & Co. Investment Partners Ltd. | 10,850 | $185.3K | 0.08% | +10,850 | New |
| James Investment Research Inc | 10,578 | $180.7K | 0.02% | 00.0% | Unchanged |
| Northwest & Ethical Investments L.P. | 10,030 | $172.8K | 0.00% | 00.0% | Unchanged |
| TPG Financial Advisors, LLC | 10,017 | $171.1K | 0.06% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 8,686 | $148.4K | 0.04% | +1,508+21.0% | Added |
| Quest Partners LLC | 8,471 | $144.7K | 0.01% | −5,555−39.6% | Reduced |
| KLP Kapitalforvaltning AS | 7,300 | $124.7K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 6,968 | $119.0K | 0.00% | −1,602−18.7% | Reduced |
| Group One Trading, L.P. | 6,868 | $117.3K | 0.00% | +6,768+6,768.0% | Added |
| Clearstead Advisors, LLC | 5,001 | $85.4K | 0.00% | +10.0% | Added |
| Shell Asset Management Co | 4,212 | $72.0K | 0.01% | −5,084−54.7% | Reduced |
| Ameritas Investment Partners, Inc. | 4,164 | $71.1K | 0.00% | −1,452−25.9% | Reduced |
| DekaBank Deutsche Girozentrale | 3,843 | $65.0K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 3,514 | $60.0K | 0.00% | +404+13.0% | Added |
| SRS Capital Advisors, Inc. | 2,981 | $50.9K | 0.00% | +2,981 | New |
| Quarry LP | 2,942 | $50.2K | 0.01% | +2,942 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,906 | $49.6K | 0.00% | +214+7.9% | Added |
| Amalgamated Bank | 1,880 | $32.0K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,617 | $27.6K | 0.00% | −146−8.3% | Reduced |
| Optiver Holding B.V. | 1,510 | $25.8K | 0.00% | +1,510 | New |
| Nisa Investment Advisors, LLC | 968 | $16.5K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 870 | $14.9K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 805 | $13.7K | 0.00% | −5−0.6% | Reduced |
| Advisor Group Holdings, Inc. | 775 | $12.3K | 0.00% | +106+15.8% | Added |
| National Bank of Canada | 549 | $9.37K | 0.00% | +77+16.3% | Added |
| Clear Street Markets LLC | 472 | $8.06K | 0.00% | +472 | New |
| Parallel Advisors, LLC | 329 | $5.62K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 313 | $5.35K | 0.00% | −25−7.4% | Reduced |
| TD Waterhouse Canada Inc. | 311 | $5.28K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 286 | $5.00K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 280 | $4.78K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 248 | $4.24K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 231 | $3.94K | 0.00% | −78−25.2% | Reduced |
| Comerica Bank | 211 | $3.60K | 0.00% | +211 | New |
| EverSource Wealth Advisors, LLC | 182 | $3.11K | 0.00% | +1+0.6% | Added |
| Allworth Financial LP | 140 | $2.39K | 0.00% | +18+14.8% | Added |
| Sterling Capital Management LLC | 121 | $2.07K | 0.00% | +2+1.7% | Added |
| IFP Advisors, Inc | 96 | $1.64K | 0.00% | 00.0% | Unchanged |
| Walleye Capital LLC | 76 | $1.30K | 0.00% | +76 | New |
| Kilter Group LLC | 66 | $1.13K | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 64 | $1.09K | 0.00% | +19+42.2% | Added |
| Farther Finance Advisors, LLC | 62 | $1.06K | 0.00% | +37+148.0% | Added |
| Covestor Ltd | 53 | $1.00K | 0.00% | +27+103.8% | Added |
| Bessemer Group Inc | 73 | $1.00K | 0.00% | +73 | New |
| True Wealth Design, LLC | 58 | $991 | 0.00% | +51+728.6% | Added |
| Rothschild Investment LLC | 55 | $939 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 53 | $905 | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 51 | $872 | 0.00% | 00.0% | Unchanged |
| Sunbelt Securities, Inc. | 27 | $461 | 0.00% | +27 | New |
| CoreCap Advisors, LLC | 18 | $307 | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 12 | $206 | 0.00% | +12 | New |
| Essential Partners LLC | 12 | $205 | 0.00% | −2−14.3% | Reduced |
| SBI Securities Co., Ltd. | 12 | $205 | 0.00% | +2+20.0% | Added |
| Innovative Advisory Group, LLC | 8 | $137 | 0.00% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0 | $0 | 0.00% | −2,039,656−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −220,982−100.0% | Sold out |
| AXA S.A. | 0 | $0 | 0.00% | −175,121−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −119,962−100.0% | Sold out |
| Weiss Asset Management LP | 0 | $0 | 0.00% | −54,171−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −51,669−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −31,021−100.0% | Sold out |
| Landscape Capital Management, L.L.C. | 0 | $0 | 0.00% | −26,667−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −21,660−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −14,887−100.0% | Sold out |
| Ieq Capital, LLC | 0 | $0 | 0.00% | −14,169−100.0% | Sold out |
| Magnetar Financial LLC | 0 | $0 | 0.00% | −12,168−100.0% | Sold out |
| Cresset Asset Management, LLC | 0 | $0 | 0.00% | −12,153−100.0% | Sold out |
| Quantinno Capital Management LP | 0 | $0 | 0.00% | −11,746−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −10,368−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −6,311−100.0% | Sold out |