Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Zymeworks Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 184
- +3 vs. Q2 2025
- Shares held
- 73.7M
- −1.71M (−2.3%) vs. Q2 2025
- Total value
- $1.26B
- +$312.6M (+33.0%) vs. Q2 2025
- New holders
- 25
- 61 more added
- Sold out
- 22
- 65 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Innovative Advisory Group, LLC | 8 | $137 | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 12 | $205 | 0.00% | −2−14.3% | Reduced |
| SBI Securities Co., Ltd. | 12 | $205 | 0.00% | +2+20.0% | Added |
| Smartleaf Asset Management LLC | 12 | $206 | 0.00% | +12 | New |
| CoreCap Advisors, LLC | 18 | $307 | 0.00% | 00.0% | Unchanged |
| Sunbelt Securities, Inc. | 27 | $461 | 0.00% | +27 | New |
| UMA Financial Services, Inc. | 51 | $872 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 53 | $905 | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 55 | $939 | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 58 | $991 | 0.00% | +51+728.6% | Added |
| Covestor Ltd | 53 | $1.00K | 0.00% | +27+103.8% | Added |
| Bessemer Group Inc | 73 | $1.00K | 0.00% | +73 | New |
| Farther Finance Advisors, LLC | 62 | $1.06K | 0.00% | +37+148.0% | Added |
| Bare Financial Services, Inc | 64 | $1.09K | 0.00% | +19+42.2% | Added |
| Kilter Group LLC | 66 | $1.13K | 0.00% | 00.0% | Unchanged |
| Walleye Capital LLC | 76 | $1.30K | 0.00% | +76 | New |
| IFP Advisors, Inc | 96 | $1.64K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 121 | $2.07K | 0.00% | +2+1.7% | Added |
| Allworth Financial LP | 140 | $2.39K | 0.00% | +18+14.8% | Added |
| EverSource Wealth Advisors, LLC | 182 | $3.11K | 0.00% | +1+0.6% | Added |
| Comerica Bank | 211 | $3.60K | 0.00% | +211 | New |
| Truvestments Capital LLC | 231 | $3.94K | 0.00% | −78−25.2% | Reduced |
| US Bancorp | 248 | $4.24K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 280 | $4.78K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 286 | $5.00K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 311 | $5.28K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 313 | $5.35K | 0.00% | −25−7.4% | Reduced |
| Parallel Advisors, LLC | 329 | $5.62K | 0.00% | 00.0% | Unchanged |
| Clear Street Markets LLC | 472 | $8.06K | 0.00% | +472 | New |
| National Bank of Canada | 549 | $9.37K | 0.00% | +77+16.3% | Added |
| Advisor Group Holdings, Inc. | 775 | $12.3K | 0.00% | +106+15.8% | Added |
| GAMMA Investing LLC | 805 | $13.7K | 0.00% | −5−0.6% | Reduced |
| Federation des caisses Desjardins du Quebec | 870 | $14.9K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 968 | $16.5K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 1,510 | $25.8K | 0.00% | +1,510 | New |
| GF Fund Management Co. Ltd. | 1,617 | $27.6K | 0.00% | −146−8.3% | Reduced |
| Amalgamated Bank | 1,880 | $32.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,906 | $49.6K | 0.00% | +214+7.9% | Added |
| Quarry LP | 2,942 | $50.2K | 0.01% | +2,942 | New |
| SRS Capital Advisors, Inc. | 2,981 | $50.9K | 0.00% | +2,981 | New |
| FMR LLC | 3,514 | $60.0K | 0.00% | +404+13.0% | Added |
| DekaBank Deutsche Girozentrale | 3,843 | $65.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 4,164 | $71.1K | 0.00% | −1,452−25.9% | Reduced |
| Shell Asset Management Co | 4,212 | $72.0K | 0.01% | −5,084−54.7% | Reduced |
| Clearstead Advisors, LLC | 5,001 | $85.4K | 0.00% | +10.0% | Added |
| Group One Trading, L.P. | 6,868 | $117.3K | 0.00% | +6,768+6,768.0% | Added |
| CWM, LLC | 6,968 | $119.0K | 0.00% | −1,602−18.7% | Reduced |
| KLP Kapitalforvaltning AS | 7,300 | $124.7K | 0.00% | 00.0% | Unchanged |
| Quest Partners LLC | 8,471 | $144.7K | 0.01% | −5,555−39.6% | Reduced |
| Virtus Investment Advisers, Inc. | 8,686 | $148.4K | 0.04% | +1,508+21.0% | Added |
| TPG Financial Advisors, LLC | 10,017 | $171.1K | 0.06% | 00.0% | Unchanged |
| Northwest & Ethical Investments L.P. | 10,030 | $172.8K | 0.00% | 00.0% | Unchanged |
| James Investment Research Inc | 10,578 | $180.7K | 0.02% | 00.0% | Unchanged |
| Ewing Morris & Co. Investment Partners Ltd. | 10,850 | $185.3K | 0.08% | +10,850 | New |
| Arizona State Retirement System | 11,059 | $188.9K | 0.00% | −100−0.9% | Reduced |
| Janney Montgomery Scott LLC | 11,067 | $189.0K | 0.00% | −500−4.3% | Reduced |
| ProShare Advisors LLC | 11,201 | $191.3K | 0.00% | −1,464−11.6% | Reduced |
| Tower Research Capital LLC (TRC) | 11,301 | $193.0K | 0.01% | +6,354+128.4% | Added |
| Two Sigma Securities, LLC | 12,225 | $208.8K | 0.03% | +12,225 | New |
| China Universal Asset Management Co., Ltd. | 13,176 | $225.0K | 0.02% | −820−5.9% | Reduced |
| New York State Common Retirement Fund | 13,371 | $228.4K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 13,624 | $233.0K | 0.00% | +4,953+57.1% | Added |
| Police & Firemen's Retirement System of New Jersey | 14,205 | $242.6K | 0.00% | +2,536+21.7% | Added |
| Brevan Howard Capital Management LP | 14,518 | $248.0K | 0.00% | +3,890+36.6% | Added |
| Envestnet Asset Management Inc | 14,574 | $248.9K | 0.00% | −32−0.2% | Reduced |
| Lazard Asset Management LLC | 15,308 | $261.5K | 0.00% | +15,308 | New |
| State Board of Administration of Florida Retirement System | 15,340 | $262.0K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 15,460 | $264.1K | 0.00% | +5,153+50.0% | Added |
| Fox Run Management, L.L.C. | 16,145 | $275.8K | 0.04% | +16,145 | New |
| Intech Investment Management LLC | 16,982 | $290.1K | 0.00% | −6,181−26.7% | Reduced |
| Manufacturers Life Insurance Company, The | 17,574 | $300.2K | 0.00% | −1,496−7.8% | Reduced |
| PharVision Advisers, LLC | 17,790 | $303.9K | 0.17% | +17,790 | New |
| Janus Henderson Group PLC | 18,200 | $311.0K | 0.00% | 00.0% | Unchanged |
| DLD Asset Management, LP | 20,000 | $341.6K | 0.04% | +20,000 | New |
| Duncan Williams Asset Management, LLC | 22,095 | $377.4K | 0.11% | 00.0% | Unchanged |
| Vinva Investment Management Ltd | 14,594 | $382.4K | 0.01% | +14,594 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 22,945 | $391.9K | 0.00% | −3,918−14.6% | Reduced |
| Ritholtz Wealth Management | 24,722 | $422.3K | 0.01% | −513−2.0% | Reduced |
| Price T Rowe Associates Inc | 26,816 | $459.0K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 27,314 | $466.5K | 0.00% | +1,925+7.6% | Added |
| Bank of Montreal | 27,642 | $472.1K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 28,369 | $484.5K | 0.00% | −15,394−35.2% | Reduced |
| Simplex Trading, LLC | 28,761 | $491.0K | 0.01% | +22,316+346.3% | Added |
| Massachusetts Financial Services Co | 29,015 | $495.6K | 0.00% | +1,906+7.0% | Added |
| Journey Strategic Wealth LLC | 29,050 | $496.2K | 0.01% | +100.0% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 29,708 | $507.4K | 0.00% | −226−0.8% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 30,432 | $519.8K | 0.00% | +16,132+112.8% | Added |
| Commonwealth Equity Services, LLC | 31,237 | $534.0K | 0.00% | −933−2.9% | Reduced |
| Campbell & CO Investment Adviser LLC | 32,493 | $555.0K | 0.04% | +17,508+116.8% | Added |
| Boothbay Fund Management, LLC | 32,757 | $559.5K | 0.01% | +32,757 | New |
| MetLife Investment Management | 33,309 | $568.9K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 33,390 | $570.3K | 0.00% | −11,575−25.7% | Reduced |
| Franklin Resources Inc | 33,821 | $577.7K | 0.00% | +33,821 | New |
| JPMorgan Chase & Co | 33,884 | $578.7K | 0.00% | −407,806−92.3% | Reduced |
| Victory Capital Management Inc | 34,510 | $589.4K | 0.00% | −100−0.3% | Reduced |
| California State Teachers Retirement System | 35,231 | $601.7K | 0.00% | −7,642−17.8% | Reduced |
| Oxford Asset Management LLP | 36,359 | $621.0K | 0.20% | +36,359 | New |
| Dark Forest Capital Management LP | 37,167 | $634.8K | 0.02% | −59,822−61.7% | Reduced |
| HSBC Holdings PLC | 37,600 | $639.6K | 0.00% | +1,103+3.0% | Added |
| Tudor Investment Corp Et Al | 37,583 | $641.9K | 0.00% | +3,290+9.6% | Added |