Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Zymeworks Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 182
- −2 vs. Q1 2025
- Shares held
- 75.6M
- +5.10M (+7.2%) vs. Q1 2025
- Total value
- $949.0M
- +$109.0M (+13.0%) vs. Q1 2025
- New holders
- 28
- 63 more added
- Sold out
- 30
- 55 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Man Group plc | 35,406 | $444.3K | 0.00% | +24,547+226.1% | Added |
| HSBC Holdings PLC | 36,497 | $461.3K | 0.00% | +36,497 | New |
| O'Shaughnessy Asset Management, LLC | 41,224 | $517.4K | 0.00% | −55,105−57.2% | Reduced |
| California State Teachers Retirement System | 42,873 | $538.1K | 0.00% | −910−2.1% | Reduced |
| Legal & General Group Plc | 43,763 | $549.2K | 0.00% | −3,027−6.5% | Reduced |
| Prudential Financial Inc | 44,965 | $564.3K | 0.00% | +2,395+5.6% | Added |
| STRS Ohio | 46,300 | $581.1K | 0.00% | +46,300 | New |
| Alliancebernstein L.P. | 50,030 | $627.9K | 0.00% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 51,669 | $648.0K | 0.01% | −81,651−61.2% | Reduced |
| NEOS Investment Management LLC | 51,855 | $650.8K | 0.01% | +18,854+57.1% | Added |
| Tema ETFs LLC | 51,855 | $650.8K | 0.17% | +18,854+57.1% | Added |
| Virginia Retirement Systems Et Al | 54,075 | $678.6K | 0.00% | +9,900+22.4% | Added |
| Weiss Asset Management LP | 54,171 | $679.8K | 0.01% | +54,171 | New |
| Stifel Financial Corp | 69,730 | $875.1K | 0.00% | +2,700+4.0% | Added |
| Qube Research & Technologies Ltd | 69,874 | $876.9K | 0.00% | +69,874 | New |
| Fisher Asset Management, LLC | 71,979 | $903.3K | 0.00% | +50.0% | Added |
| Royal Bank of Canada | 72,983 | $915.0K | 0.00% | +16,212+28.6% | Added |
| Swiss National Bank | 73,100 | $917.4K | 0.00% | −7,000−8.7% | Reduced |
| Acuta Capital Partners, LLC | 83,655 | $1.05M | 1.47% | +15,196+22.2% | Added |
| Susquehanna Portfolio Strategies, LLC | 85,728 | $1.08M | 0.02% | +85,728 | New |
| Rhumbline Advisers | 86,083 | $1.08M | 0.00% | +3,345+4.0% | Added |
| Invesco Ltd. | 89,371 | $1.12M | 0.00% | +11,165+14.3% | Added |
| Bank of America Corp | 90,378 | $1.13M | 0.00% | +28,247+45.5% | Added |
| North Growth Management Ltd. | 97,000 | $1.22M | 0.23% | 00.0% | Unchanged |
| Dark Forest Capital Management LP | 96,989 | $1.22M | 0.05% | −8,840−8.4% | Reduced |
| Millennium Management LLC | 116,102 | $1.46M | 0.00% | −179,504−60.7% | Reduced |
| Algert Global LLC | 118,104 | $1.48M | 0.03% | +118,104 | New |
| Cubist Systematic Strategies, LLC | 119,962 | $1.51M | 0.02% | +119,962 | New |
| Barclays PLC | 122,820 | $1.54M | 0.00% | +47,390+62.8% | Added |
| Charles Schwab Investment Management Inc | 124,204 | $1.56M | 0.00% | −9,435−7.1% | Reduced |
| Raymond James Financial Inc | 124,435 | $1.56M | 0.00% | +7,724+6.6% | Added |
| Bank of New York Mellon Corp | 133,090 | $1.67M | 0.00% | +12,363+10.2% | Added |
| Kennedy Capital Management, Inc. | 146,954 | $1.84M | 0.04% | +10,635+7.8% | Added |
| Squarepoint Ops LLC | 155,599 | $1.95M | 0.00% | +91,997+144.6% | Added |
| Citigroup Inc | 155,998 | $1.96M | 0.00% | +114,800+278.7% | Added |
| AQR Capital Management LLC | 166,143 | $2.09M | 0.00% | +117,658+242.7% | Added |
| Wells Fargo & Company | 166,428 | $2.09M | 0.00% | +66,119+65.9% | Added |
| AXA S.A. | 175,121 | $2.20M | 0.01% | +175,121 | New |
| Wellington Management Group LLP | 180,690 | $2.27M | 0.00% | −1,556−0.9% | Reduced |
| Federated Hermes, Inc. | 182,270 | $2.29M | 0.00% | +358+0.2% | Added |
| Tejara Capital Ltd | 200,150 | $2.51M | 1.16% | +10,741+5.7% | Added |
| Norges Bank | 201,700 | $2.53M | 0.00% | 00.0% | Unchanged |
| Hillsdale Investment Management Inc. | 205,022 | $2.57M | 0.09% | −31,903−13.5% | Reduced |
| Picton Mahoney Asset Management | 207,602 | $2.60M | 0.04% | −427−0.2% | Reduced |
| Opaleye Management Inc. | 210,000 | $2.64M | 0.53% | +35,000+20.0% | Added |
| Trexquant Investment LP | 220,982 | $2.77M | 0.03% | +173+0.1% | Added |
| Platinum Investment Management Ltd | 238,391 | $2.99M | 0.20% | −40,267−14.5% | Reduced |
| Citadel Advisors LLC | 246,155 | $3.09M | 0.00% | +65,485+36.2% | Added |
| UBS Group AG | 251,510 | $3.16M | 0.00% | +37,210+17.4% | Added |
| D. E. Shaw & Co., Inc. | 255,291 | $3.20M | 0.00% | +192,192+304.6% | Added |
| Susquehanna International Group, LLP | 259,137 | $3.25M | 0.00% | −92,024−26.2% | Reduced |
| Silvercrest Asset Management Group LLC | 280,726 | $3.52M | 0.02% | 00.0% | Unchanged |
| Schroder Investment Management Group | 304,666 | $3.80M | 0.00% | −17,283−5.4% | Reduced |
| Samsara BioCapital, LLC | 310,300 | $3.89M | 0.80% | −356,367−53.5% | Reduced |
| Northern Trust Corp | 349,799 | $4.39M | 0.00% | −37,124−9.6% | Reduced |
| Jupiter Asset Management Ltd | 369,499 | $4.64M | 0.04% | 00.0% | Unchanged |
| Granahan Investment Management Inc | 380,783 | $4.78M | 0.19% | −26,806−6.6% | Reduced |
| Goldman Sachs Group Inc | 428,857 | $5.38M | 0.00% | +228,810+114.4% | Added |
| JPMorgan Chase & Co | 441,690 | $5.54M | 0.00% | +403,281+1,050.0% | Added |
| Adage Capital Partners GP, L.L.C. | 476,000 | $5.97M | 0.01% | +476,000 | New |
| Assenagon Asset Management S.A. | 492,780 | $6.18M | 0.01% | −2,287−0.5% | Reduced |
| Renaissance Technologies LLC | 533,300 | $6.69M | 0.01% | +82,700+18.4% | Added |
| Nuveen, LLC | 654,916 | $8.22M | 0.00% | +456,104+229.4% | Added |
| Geode Capital Management, LLC | 705,364 | $8.85M | 0.00% | +3290.0% | Added |
| State Street Corp | 1,088,459 | $13.7M | 0.00% | +3,326+0.3% | Added |
| Tang Capital Management LLC | 1,100,000 | $13.8M | 0.70% | 00.0% | Unchanged |
| Nextech Invest, Ltd. | 1,113,946 | $14.0M | 2.65% | 00.0% | Unchanged |
| Vestal Point Capital, LP | 1,150,000 | $14.4M | 0.76% | +650,000+130.0% | Added |
| Dimensional Fund Advisors LP | 1,192,432 | $15.0M | 0.00% | +112,974+10.5% | Added |
| Perceptive Advisors LLC | 1,275,274 | $16.0M | 0.60% | −589,398−31.6% | Reduced |
| Prosight Management, LP | 1,309,904 | $16.4M | 4.01% | +352,675+36.8% | Added |
| Deutsche Bank AG | 1,544,763 | $19.4M | 0.01% | −7,849−0.5% | Reduced |
| Blackstone Group Inc. | 1,656,790 | $20.8M | 0.09% | +274,203+19.8% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,039,656 | $25.6M | 0.06% | −158,223−7.2% | Reduced |
| UBS Asset Management Americas Inc | 2,459,513 | $30.9M | 0.01% | −1,420,432−36.6% | Reduced |
| Vanguard Group Inc | 2,464,693 | $30.9M | 0.00% | +697,652+39.5% | Added |
| BlackRock, Inc. | 3,794,272 | $47.6M | 0.00% | −295,149−7.2% | Reduced |
| Redmile Group, LLC | 4,150,627 | $52.1M | 5.54% | −638,318−13.3% | Reduced |
| Morgan Stanley | 4,177,614 | $52.4M | 0.00% | +104,151+2.6% | Added |
| BVF Inc | 4,308,935 | $54.1M | 1.93% | 00.0% | Unchanged |
| Rubric Capital Management LP | 4,710,551 | $59.1M | 0.95% | +372,107+8.6% | Added |
| EcoR1 Capital, LLC | 22,970,388 | $288.3M | 17.11% | +5,710,840+33.1% | Added |
| Bridgeway Capital Management, LLC | 0 | $0 | 0.00% | −766,944−100.0% | Sold out |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −400,000−100.0% | Sold out |
| Empowered Funds, LLC | 0 | $0 | 0.00% | −360,044−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −247,959−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −114,156−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −95,394−100.0% | Sold out |
| Aquilo Capital Management, LLC | 0 | $0 | 0.00% | −84,482−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −41,607−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −32,160−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −26,719−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −21,900−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −17,090−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −12,102−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −12,040−100.0% | Sold out |
| One Wealth Advisors, LLC | 0 | $0 | 0.00% | −10,404−100.0% | Sold out |
| Exchange Traded Concepts, LLC | 0 | $0 | 0.00% | −10,126−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −3,787−100.0% | Sold out |