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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Zymeworks Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
174
+13 vs. Q3 2024
Shares held
66.5M
−22.8K (0.0%) vs. Q3 2024
Total value
$973.2M
+$139.4M (+16.7%) vs. Q3 2024
New holders
33
47 more added
Sold out
20
61 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 174 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ4 2024: $973.2M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2024.

Institutions holding ZYME in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Public Employees Retirement System of Ohio50,583$740.5K0.00%−10,400−17.1%Reduced
Susquehanna International Group, LLP51,516$754.2K0.00%+35,130+214.4%Added
Victory Capital Management Inc51,580$755.1K0.00%−2,810−5.2%Reduced
Envestnet Asset Management Inc54,090$791.9K0.00%−11,588−17.6%Reduced
Citadel Advisors LLC58,358$854.4K0.00%+37,550+180.5%Added
Voya Investment Management LLC59,514$871.3K0.00%+40,172+207.7%Added
Raymond James Financial Inc60,642$887.8K0.00%+60,642New
Royal Bank of Canada60,926$893.0K0.00%−952−1.5%Reduced
Fisher Asset Management, LLC63,600$931.1K0.00%00.0%Unchanged
Stifel Financial Corp64,330$941.8K0.00%−9,324−12.7%Reduced
State of Wisconsin Investment Board65,381$957.2K0.00%−19,777−23.2%Reduced
Acuta Capital Partners, LLC67,240$984.4K0.99%+67,240New
Invesco Ltd.69,382$1.02M0.00%−93,657−57.4%Reduced
Ritholtz Wealth Management74,466$1.09M0.03%+4,297+6.1%Added
Credit Agricole S A75,000$1.10M0.00%00.0%Unchanged
Citigroup Inc83,136$1.22M0.00%+3,246+4.1%Added
Swiss National Bank90,200$1.32M0.00%00.0%Unchanged
HRT Financial LP95,974$1.41M0.01%+47,166+96.6%Added
North Growth Management Ltd.97,000$1.42M0.27%00.0%Unchanged
Susquehanna Fundamental Investments, LLC97,553$1.43M0.02%+97,553New
Trexquant Investment LP101,996$1.49M0.02%+101,996New
Rhumbline Advisers103,876$1.52M0.00%+15,920+18.1%Added
JPMorgan Chase & Co111,983$1.64M0.00%+72,703+185.1%Added
Bank of New York Mellon Corp120,683$1.77M0.00%−129,308−51.7%Reduced
Ameriprise Financial Inc121,526$1.78M0.00%−15,800−11.5%Reduced
Charles Schwab Investment Management Inc131,306$1.92M0.00%−1,492−1.1%Reduced
O'Shaughnessy Asset Management, LLC132,577$1.94M0.02%−12,271−8.5%Reduced
Kennedy Capital Management, Inc.139,953$2.05M0.05%−3,627−2.5%Reduced
Wells Fargo & Company164,058$2.40M0.00%−13,352−7.5%Reduced
UBS Group AG166,896$2.44M0.00%+31,341+23.1%Added
Federated Hermes, Inc.181,626$2.66M0.01%+3,367+1.9%Added
Vestal Point Capital, LP185,000$2.71M0.16%−430,000−69.9%Reduced
Norges Bank201,700$2.95M0.00%00.0%Unchanged
Picton Mahoney Asset Management206,569$3.02M0.11%−38,087−15.6%Reduced
Nuveen Asset Management, LLC207,023$3.03M0.00%+886+0.4%Added
Panagora Asset Management Inc214,338$3.14M0.01%+113,472+112.5%Added
Wellington Management Group LLP219,098$3.21M0.00%−24,091−9.9%Reduced
Barclays PLC220,890$3.23M0.00%+66,506+43.1%Added
Hillsdale Investment Management Inc.230,025$3.37M0.17%+230,025New
Acadian Asset Management LLC230,970$3.38M0.01%−214,806−48.2%Reduced
Goldman Sachs Group Inc249,960$3.66M0.00%−1,517−0.6%Reduced
Silvercrest Asset Management Group LLC282,345$4.13M0.03%−2,770−1.0%Reduced
Renaissance Technologies LLC285,700$4.18M0.01%+101,100+54.8%Added
Platinum Investment Management Ltd306,460$4.49M0.26%−21,062−6.4%Reduced
Point72 Asset Management, L.P.330,127$4.83M0.01%+280,544+565.8%Added
Schroder Investment Management Group337,161$4.89M0.00%+337,161New
Empowered Funds, LLC352,753$5.16M0.08%+17,092+5.1%Added
Jacobs Levy Equity Management, Inc356,168$5.21M0.02%−166,472−31.9%Reduced
Jupiter Asset Management Ltd369,499$5.41M0.05%−57,445−13.5%Reduced
Northern Trust Corp394,830$5.78M0.00%+23,903+6.4%Added
Granahan Investment Management Inc411,120$6.02M0.25%−202,383−33.0%Reduced
Walleye Capital LLC452,804$6.63M0.06%+452,804New
Blackstone Group Inc.569,715$8.34M0.04%+544,633+2,171.4%Added
Assenagon Asset Management S.A.642,251$9.40M0.02%+311,107+93.9%Added
Geode Capital Management, LLC689,884$10.1M0.00%−24,031−3.4%Reduced
Bridgeway Capital Management, LLC759,653$11.1M0.25%+17,092+2.3%Added
Prosight Management, LP820,000$12.0M3.36%−97,599−10.6%Reduced
Dimensional Fund Advisors LP972,742$14.2M0.00%+123,240+14.5%Added
Samsara BioCapital, LLC1,000,000$14.6M2.01%00.0%Unchanged
State Street Corp1,084,961$15.9M0.00%−86,816−7.4%Reduced
Tang Capital Management LLC1,100,000$16.1M1.07%00.0%Unchanged
Nextech Invest AG1,113,946$16.3M2.65%00.0%Unchanged
Farallon Capital Management, L.L.C.1,329,974$19.5M0.10%−31,026−2.3%Reduced
UBS Asset Management Americas Inc1,365,111$20.0M0.00%−158,973−10.4%Reduced
Deutsche Bank AG1,546,772$22.6M0.01%+17,849+1.2%Added
Perceptive Advisors LLC2,130,020$31.2M0.87%−50,000−2.3%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,137,653$31.3M0.08%+192,162+9.9%Added
Vanguard Group Inc2,493,288$36.5M0.00%−365,226−12.8%Reduced
Rubric Capital Management LP3,917,331$57.3M1.04%00.0%Unchanged
BlackRock, Inc.4,184,956$61.3M0.00%−78,639−1.8%Reduced
Morgan Stanley4,201,437$61.5M0.00%−905,432−17.7%Reduced
BVF Inc4,308,935$63.1M2.14%−299,000−6.5%Reduced
Redmile Group, LLC4,840,463$70.9M4.94%−261,448−5.1%Reduced
EcoR1 Capital, LLC15,028,079$220.0M8.81%+1,590,606+11.8%Added
Arrowstreet Capital, Limited Partnership0$00.00%−407,771−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−235,900−100.0%Sold out
Marshall Wace, LLP0$00.00%−209,765−100.0%Sold out
J. Goldman & Co LP0$00.00%−119,956−100.0%Sold out
Deerfield Management Company, L.P. (Series C)0$00.00%−49,546−100.0%Sold out
Caxton Associates LP0$00.00%−45,810−100.0%Sold out
Squarepoint Ops LLC0$00.00%−33,438−100.0%Sold out
Susquehanna Portfolio Strategies, LLC0$00.00%−24,671−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−16,465−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−11,724−100.0%Sold out
Tocqueville Asset Management L.P.0$00.00%−10,679−100.0%Sold out
Virtus Investment Advisers, Inc.0$00.00%−9,819−100.0%Sold out
Lazard Asset Management LLC0$00.00%−9,561−100.0%Sold out
nVerses Capital, LLC0$00.00%−6,300−100.0%Sold out
Virtus Fund Advisers, LLC0$00.00%−1,908−100.0%Sold out
Allspring Global Investments Holdings, LLC0$00.00%−696−100.0%Sold out
Stonehage Fleming Financial Services Holdings Ltd0$00.00%−550−100.0%Sold out
Frazier Financial Advisors, LLC0$00.00%−226−100.0%Sold out
Asset Dedication, LLC0$00.00%−47−100.0%Sold out
Capital Performance Advisors LLP0$00.00%−15−100.0%Sold out
Raymond James Financial Services Advisors, Inc.––––Not filed
Raymond James & Associates––––Not filed