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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Tanglewood Legacy Advisors, LLC25$11.2K0.00%00.0%Unchanged
Main Street Group, LTD25$11.2K0.00%+25New
Dunhill Financial, LLC25$11.4K0.00%+4+19.0%Added
ORG Wealth Partners, LLC26$11.6K0.00%+26New
Tidemark, LLC26$11.6K0.00%+3+13.0%Added
Team Financial Group, LLC27$12.1K0.01%00.0%Unchanged
ZRC Wealth Management, LLC27$12.1K0.00%+1+3.8%Added
DiNuzzo Private Wealth, Inc.27$12.1K0.00%+1+3.8%Added
Virginia Estate & Retirement Planning Advisors Inc.27$12.1K0.05%+27New
Proffitt & Goodson Inc28$12.5K0.00%00.0%Unchanged
Lummis Asset Management, LP29$12.9K0.01%00.0%Unchanged
United Financial Planning Group LLC29$12.9K0.01%+13+81.3%Added
Frazier Financial Advisors, LLC29$12.9K0.01%+21+262.5%Added
FWL Investment Management, LLC30$13.4K0.00%00.0%Unchanged
Caitlin John, LLC31$13.8K0.01%00.0%Unchanged
SJS Investment Consulting Inc.31$13.8K0.00%+4+14.8%Added
Strategic Wealth Advisors LLC32$14.0K0.01%00.0%Unchanged
City Holding Co32$14.3K0.00%00.0%Unchanged
Orion Capital Management LLC32$14.3K0.00%00.0%Unchanged
Evermay Wealth Management LLC32$14.3K0.00%−4−11.1%Reduced
Beaird Harris Wealth Management, LLC33$14.7K0.00%00.0%Unchanged
Indiana Trust & Investment Management CO35$15.6K0.00%00.0%Unchanged
Bravera Wealth35$15.6K0.01%+22+169.2%Added
Valued Wealth Advisors LLC37$16.4K0.01%−7−15.9%Reduced
IMG Wealth Management, Inc.37$16.5K0.01%−31−45.6%Reduced
Trust Co38$17.0K0.00%00.0%Unchanged
Essential Partners LLC38$17.0K0.01%+22+137.5%Added
Heritage Wealth Advisors38$17.0K0.00%+35+1,166.7%Added
Avion Wealth39$17.0K0.00%+5+14.7%Added
Archer Investment Corp39$17.4K0.00%−35−47.3%Reduced
Measured Wealth Private Client Group, LLC39$17.4K0.00%00.0%Unchanged
Private Wealth Management Group, LLC40$17.9K0.00%+5+14.3%Added
Marquette Asset Management, LLC42$18.8K0.00%00.0%Unchanged
Horizon Financial Services, LLC43$19.2K0.01%+26+152.9%Added
DT Investment Partners, LLC44$19.6K0.00%00.0%Unchanged
Burk Holdings LLC45$20.1K0.01%+45New
True Wealth Design, LLC46$20.5K0.01%+34+283.3%Added
Activest Wealth Management46$20.6K0.00%+40+666.7%Added
Evelyn Partners Asset Management Ltd47$21.0K0.01%00.0%Unchanged
Greykasell Wealth Strategies, Inc.47$21.0K0.01%+38+422.2%Added
South State Corp.47$21.0K0.00%−15−24.2%Reduced
Scarborough Advisors, LLC47$21.0K0.00%00.0%Unchanged
Wilkerson Advisory Group LLC48$21.4K0.01%+15+45.5%Added
Sachetta, LLC49$21.9K0.01%00.0%Unchanged
Hilton Head Capital Partners, LLC50$22.3K0.01%00.0%Unchanged
Quaker Wealth Management, LLC50$22.3K0.01%+2+4.2%Added
Bullock Wealth Management Group50$22.4K0.01%−5−9.1%Reduced
Evolution Wealth Management Inc.52$23.2K0.02%+39+300.0%Added
Synergy Investment Management, LLC53$23.7K0.01%+53New
Pinnacle Bancorp, Inc.54$24.1K0.01%00.0%Unchanged
Aventura Private Wealth, LLC54$24.1K0.01%00.0%Unchanged
Cedar Mountain Advisors, LLC54$24.1K0.00%+16+42.1%Added
Riverview Trust Co55$24.6K0.03%00.0%Unchanged
Wedbush Fund Advisers, LLC57$25.5K0.00%+57New
Strategic Investment Solutions, Inc.58$25.9K0.01%00.0%Unchanged
Chilton Capital Management LLC58$25.9K0.00%+57+5,700.0%Added
Access Investment Management LLC60$26.8K0.01%00.0%Unchanged
Swiss Re Ltd61$27.2K0.17%00.0%Unchanged
BFSG, LLC61$27.2K0.00%+7+13.0%Added
Prosperity Bancshares Inc61$27.2K0.02%+18+41.9%Added
North Star Investment Management Corp.62$27.7K0.00%00.0%Unchanged
Canton Hathaway, LLC62$27.7K0.01%00.0%Unchanged
Raffa Wealth Management, LLC62$27.7K0.00%+1+1.6%Added
Thurston, Springer, Miller, Herd & Titak, Inc.63$28.1K0.01%−13−17.1%Reduced
Chesapeake Asset Management LLC63$28.1K0.02%00.0%Unchanged
Pingora Partners LLC65$29.0K0.02%00.0%Unchanged
Estabrook Capital Management69$30.8K0.00%00.0%Unchanged
Capital Advisors, Ltd. LLC69$31.0K0.00%−8−10.4%Reduced
Dogwood Wealth Management LLC72$32.2K0.01%+33+84.6%Added
Vega Investment Solutions73$32.6K0.01%00.0%Unchanged
Founders Capital Management75$33.5K0.02%00.0%Unchanged
Fortitude Family Office, LLC75$33.5K0.01%+24+47.1%Added
Ogorek Anthony Joseph78$34.0K0.01%00.0%Unchanged
Abound Wealth Management76$34.1K0.01%+6+8.6%Added
Clayton Financial Group LLC77$34.4K0.02%00.0%Unchanged
SOA Wealth Advisors, LLC.78$34.8K0.01%00.0%Unchanged
Legacy Wealth Managment, LLC78$34.8K0.02%+6+8.3%Added
Financial Management Professionals, Inc.80$35.7K0.00%+4+5.3%Added
First Command Advisory Services, Inc.81$36.2K0.00%+2+2.5%Added
TD Capital Management LLC82$36.6K0.00%+7+9.3%Added
Stone House Investment Management, LLC83$37.1K0.01%+6+7.8%Added
Rational Advisors LLC84$37.5K0.00%00.0%Unchanged
Rialto Wealth Management, LLC86$38.4K0.01%+83+2,766.7%Added
Centerpoint Advisors, LLC87$39.0K0.01%00.0%Unchanged
Wolff Wiese Magana LLC89$39.7K0.02%00.0%Unchanged
High Note Wealth, LLC93$41.5K0.01%+8+9.4%Added
Fideuram Asset Management (Ireland) dac90$42.4K0.01%−9,786−99.1%Reduced
University of Texas/Texas Am Investment Managment Co95$42.4K0.01%00.0%Unchanged
Entrust Financial LLC96$42.9K0.03%00.0%Unchanged
Innovative Asset Advisors Group, LLC96$42.9K0.02%+96New
JFS Wealth Advisors, LLC98$43.8K0.00%−16−14.0%Reduced
Wall Street Access Asset Management, LLC100$44.5K0.01%00.0%Unchanged
Spirit of America Management Corp100$44.7K0.01%00.0%Unchanged
Sfam, LLC100$44.7K0.04%00.0%Unchanged
MPWM Advisory Solutions, LLC100$44.7K0.02%00.0%Unchanged
Geneos Wealth Management Inc.101$45.1K0.00%−1−1.0%Reduced
Midwest Capital Advisors, LLC101$45.1K0.02%00.0%Unchanged
Arlington Trust Co LLC101$45.1K0.00%+89+741.7%Added
Kemnay Advisory Services Inc.102$45.5K0.01%+1+1.0%Added
Catalyst Capital Advisors LLC107$47.8K0.00%+9+9.2%Added