Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wimmer Associates 1, LLC | 5,526 | $2.51M | 1.16% | +71+1.3% | Added |
| BLI - Banque de Luxembourg Investments | 5,500 | $2.50M | 0.07% | −700−11.3% | Reduced |
| Ascent Group, LLC | 5,495 | $2.49M | 0.09% | −1,124−17.0% | Reduced |
| Mediolanum International Funds Ltd | 5,487 | $2.49M | 0.02% | −3,057−35.8% | Reduced |
| Burney Co | 5,468 | $2.48M | 0.08% | −1,163−17.5% | Reduced |
| Highview Capital Management LLC | 5,409 | $2.45M | 0.87% | −294−5.2% | Reduced |
| Cooper Financial Group | 5,341 | $2.42M | 0.26% | +3,021+130.2% | Added |
| Glenmede Trust Co NA | 5,339 | $2.42M | 0.01% | +5,339 | New |
| Signaturefd, LLC | 5,305 | $2.41M | 0.04% | +202+4.0% | Added |
| Ballentine Partners, LLC | 5,290 | $2.40M | 0.03% | +200+3.9% | Added |
| Nwam LLC | 5,038 | $2.40M | 0.13% | −39−0.8% | Reduced |
| Vise Technologies, Inc. | 5,259 | $2.38M | 0.05% | +1,036+24.5% | Added |
| Wealthcare Advisory Partners LLC | 5,259 | $2.38M | 0.05% | +130+2.5% | Added |
| D.A. Davidson & Co. | 5,251 | $2.38M | 0.01% | +154+3.0% | Added |
| Bamco Inc | 5,200 | $2.36M | 0.01% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 5,189 | $2.35M | 0.04% | +134+2.7% | Added |
| Sand Hill Global Advisors, LLC | 5,176 | $2.35M | 0.08% | −1,550−23.0% | Reduced |
| Scotia Capital Inc. | 5,165 | $2.34M | 0.01% | −756−12.8% | Reduced |
| Te Ahumairangi Investment Management Ltd | 5,135 | $2.33M | 0.42% | −590−10.3% | Reduced |
| Tiaa Trust, National Association | 5,129 | $2.33M | 0.01% | −153−2.9% | Reduced |
| Hager Investment Management Services, LLC | 5,084 | $2.30M | 1.26% | −188−3.6% | Reduced |
| Westerkirk Capital Inc. | 5,071 | $2.30M | 0.22% | +429+9.2% | Added |
| Machina Capital S.A.S. | 5,064 | $2.30M | 0.44% | −6,103−54.7% | Reduced |
| Summit Trail Advisors, LLC | 5,057 | $2.29M | 0.04% | −427−7.8% | Reduced |
| Legacy Capital Wealth Management, LLC | 5,043 | $2.29M | 1.38% | +5,043 | New |
| Leonteq Securities AG | 5,026 | $2.28M | 0.12% | −2,002−28.5% | Reduced |
| Central Pacific Bank - Trust Division | 5,026 | $2.28M | 0.28% | +24+0.5% | Added |
| TFR Capital, LLC. | 5,026 | $2.28M | 0.75% | +91+1.8% | Added |
| Advisory Services Network, LLC | 5,009 | $2.27M | 0.03% | +162+3.3% | Added |
| Meiji Yasuda Life Insurance Co | 5,005 | $2.27M | 0.07% | −33−0.7% | Reduced |
| Knollwood Investment Advisory, LLC | 4,988 | $2.26M | 0.21% | 00.0% | Unchanged |
| Aaron Wealth Advisors | 4,925 | $2.23M | 0.12% | +1,003+25.6% | Added |
| AlphaCore Capital LLC | 4,880 | $2.21M | 0.05% | −375−7.1% | Reduced |
| Quadrant Capital Group LLC | 4,850 | $2.20M | 0.07% | −825−14.5% | Reduced |
| Fiduciary Alliance LLC | 4,828 | $2.19M | 0.14% | +4,828 | New |
| Hennion & Walsh Asset Management, Inc. | 4,812 | $2.18M | 0.08% | −1,192−19.9% | Reduced |
| Future Fund LLC | 4,803 | $2.18M | 0.77% | −384−7.4% | Reduced |
| Evergreen Capital Management LLC | 4,801 | $2.18M | 0.05% | +2,304+92.3% | Added |
| Oarsman Capital, Inc. | 4,790 | $2.17M | 0.28% | +74+1.6% | Added |
| De Burlo Group Inc | 4,785 | $2.17M | 0.26% | −240−4.8% | Reduced |
| Trustmark National Bank Trust Department | 4,763 | $2.16M | 0.14% | −68−1.4% | Reduced |
| Cito Capital Group, LLC | 4,756 | $2.16M | 0.63% | +2,700+131.3% | Added |
| GLOBALT Investments LLC | 4,743 | $2.15M | 0.08% | −29−0.6% | Reduced |
| Greenleaf Trust | 4,742 | $2.15M | 0.02% | +39+0.8% | Added |
| Integrated Wealth Concepts LLC | 4,721 | $2.14M | 0.03% | +147+3.2% | Added |
| Torrey Growth & Income Advisors | 4,719 | $2.14M | 0.74% | −681−12.6% | Reduced |
| Valeo Financial Advisors, LLC | 4,682 | $2.12M | 0.05% | −74−1.6% | Reduced |
| Oak Associates, Ltd | 4,677 | $2.12M | 0.13% | −94−2.0% | Reduced |
| Hedeker Wealth, LLC | 4,665 | $2.11M | 0.44% | −2,996−39.1% | Reduced |
| Engineers Gate Manager LP | 4,664 | $2.11M | 0.03% | −10,179−68.6% | Reduced |
| AlphaCentric Advisors LLC | 4,663 | $2.11M | 2.11% | +4,663 | New |
| Impax Asset Management Group plc | 4,622 | $2.10M | 0.01% | 00.0% | Unchanged |
| Cambria Investment Management, L.P. | 4,585 | $2.08M | 0.12% | +404+9.7% | Added |
| Bangor Savings Bank | 4,576 | $2.07M | 0.17% | −323−6.6% | Reduced |
| Strategic Wealth Partners, Ltd. | 4,560 | $2.07M | 0.14% | −483−9.6% | Reduced |
| LGT Group Foundation | 4,522 | $2.05M | 0.02% | −98−2.1% | Reduced |
| Brown Brothers Harriman & Co | 4,518 | $2.05M | 0.01% | +1,399+44.9% | Added |
| McGuire Investment Group, LLC | 4,453 | $2.02M | 0.22% | 00.0% | Unchanged |
| Private Harbour Investment Management & Counsel, LLC | 4,436 | $2.01M | 2.10% | −13−0.3% | Reduced |
| Decatur Capital Management, Inc. | 4,426 | $2.01M | 0.82% | −238−5.1% | Reduced |
| Mather Group, LLC. | 4,425 | $2.01M | 0.02% | +86+2.0% | Added |
| Farther Finance Advisors, LLC | 4,421 | $2.00M | 0.02% | +1,028+30.3% | Added |
| Ritholtz Wealth Management | 4,412 | $2.00M | 0.04% | +759+20.8% | Added |
| Harrell Investment Partners, LLC | 4,377 | $1.98M | 0.47% | +12+0.3% | Added |
| Global Retirement Partners, LLC | 4,345 | $1.97M | 0.03% | +2,012+86.2% | Added |
| Signature Wealth Management Group | 4,324 | $1.96M | 0.80% | +213+5.2% | Added |
| Portside Wealth Group, LLC | 4,314 | $1.96M | 0.26% | +571+15.3% | Added |
| GKV Capital Management Co., Inc. | 4,305 | $1.95M | 0.73% | +100+2.4% | Added |
| Skopos Labs, Inc. | 4,239 | $1.95M | 0.09% | +1,462+52.6% | Added |
| Paradigm Financial Partners, LLC | 4,295 | $1.95M | 0.20% | −1,582−26.9% | Reduced |
| Nations Financial Group Inc, | 4,288 | $1.94M | 0.10% | −20.0% | Reduced |
| Everence Capital Management Inc | 4,274 | $1.94M | 0.11% | 00.0% | Unchanged |
| Oppenheimer & Co Inc | 4,272 | $1.94M | 0.03% | +668+18.5% | Added |
| Texas Yale Capital Corp. | 4,269 | $1.94M | 0.06% | +181+4.4% | Added |
| Ostrum Asset Management | 4,249 | $1.93M | 0.09% | −1,170−21.6% | Reduced |
| Pallas Capital Advisors LLC | 4,241 | $1.92M | 0.06% | +1,353+46.8% | Added |
| Meiji Yasuda America Inc | 4,216 | $1.91M | 0.44% | +4,216 | New |
| Summit Global Investments | 4,204 | $1.91M | 0.11% | −770−15.5% | Reduced |
| Dymon Asia Capital (Singapore) Pte. Ltd. | 4,200 | $1.90M | 0.42% | +4,200 | New |
| 3Chopt Investment Partners, LLC | 4,186 | $1.90M | 0.43% | −247−5.6% | Reduced |
| Waldron Private Wealth LLC | 4,184 | $1.90M | 0.07% | −116−2.7% | Reduced |
| Belpointe Asset Management LLC | 4,180 | $1.90M | 0.07% | −55−1.3% | Reduced |
| SFMG, LLC | 4,162 | $1.89M | 0.13% | −393−8.6% | Reduced |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 3,978 | $1.89M | 0.02% | +28+0.7% | Added |
| Two Sigma Investments, LP | 4,155 | $1.88M | 0.00% | +4,155 | New |
| S&CO Inc | 4,103 | $1.86M | 0.12% | 00.0% | Unchanged |
| JT Stratford LLC | 4,094 | $1.86M | 0.24% | +119+3.0% | Added |
| Mattson Financial Services, LLC | 4,085 | $1.85M | 0.43% | +39+1.0% | Added |
| ICICI Prudential Asset Management Co Ltd | 4,071 | $1.85M | 0.22% | +134+3.4% | Added |
| Mission Wealth Management, LP | 4,056 | $1.84M | 0.04% | +89+2.2% | Added |
| Clal Insurance Enterprises Holdings Ltd | 4,023 | $1.82M | 0.01% | −3−0.1% | Reduced |
| Woodstock Corp | 4,005 | $1.82M | 0.16% | 00.0% | Unchanged |
| Jones Kertz & Associates, Inc. | 4,004 | $1.82M | 0.93% | +4,004 | New |
| Lipe & Dalton | 3,996 | $1.81M | 0.90% | −250−5.9% | Reduced |
| Smartleaf Asset Management LLC | 3,985 | $1.81M | 0.07% | +752+23.3% | Added |
| TCW Group Inc | 3,988 | $1.81M | 0.01% | +3,988 | New |
| Choate Investment Advisors | 3,976 | $1.80M | 0.04% | −15−0.4% | Reduced |
| Arkadios Wealth Advisors | 3,965 | $1.80M | 0.04% | +1,631+69.9% | Added |
| Waterloo Capital, L.P. | 3,929 | $1.78M | 0.13% | +3,929 | New |
| MBM Wealth Consultants, LLC | 3,925 | $1.78M | 0.42% | +275+7.5% | Added |