Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sepio Capital, LP | 8,865 | $4.02M | 0.22% | −198−2.2% | Reduced |
| North Dakota State Investment Board | 8,821 | $4.00M | 0.15% | +8,821 | New |
| Strategic Advisors LLC | 8,775 | $3.98M | 0.62% | −79−0.9% | Reduced |
| Davidson Capital Management Inc. | 8,759 | $3.97M | 0.86% | −36−0.4% | Reduced |
| Bensler, LLC | 8,746 | $3.96M | 0.40% | −90−1.0% | Reduced |
| Empirical Finance, LLC | 8,711 | $3.95M | 0.19% | −782−8.2% | Reduced |
| Private Advisor Group, LLC | 8,694 | $3.94M | 0.02% | +1,330+18.1% | Added |
| Verition Fund Management LLC | 8,406 | $3.81M | 0.02% | −3,138−27.2% | Reduced |
| Linden Thomas Advisory Services, LLC | 8,405 | $3.81M | 0.39% | −14−0.2% | Reduced |
| NewEdge Wealth, LLC | 8,402 | $3.81M | 0.04% | +2,754+48.8% | Added |
| Northwestern Mutual Wealth Management Co | 8,300 | $3.76M | 0.00% | −7−0.1% | Reduced |
| Ashford Capital Management Inc | 8,245 | $3.74M | 0.42% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 8,133 | $3.69M | 0.01% | −103−1.3% | Reduced |
| Sumitomo Life Insurance Co | 8,126 | $3.68M | 0.10% | +1,033+14.6% | Added |
| Northwestern Mutual Investment Management Company, LLC | 8,107 | $3.68M | 0.04% | −64−0.8% | Reduced |
| SageGuard Financial Group, LLC | 8,103 | $3.67M | 0.58% | +8,103 | New |
| Commerzbank Aktiengesellschaft | 8,091 | $3.67M | 0.07% | −484−5.6% | Reduced |
| Sectoral Asset Management Inc | 8,005 | $3.63M | 2.91% | +290+3.8% | Added |
| Crestwood Advisors Group LLC | 8,003 | $3.63M | 0.06% | −1,148−12.5% | Reduced |
| Jones Financial Companies LLLP | 7,995 | $3.62M | 0.00% | +871+12.2% | Added |
| Gabelli Funds LLC | 7,984 | $3.62M | 0.02% | −7,018−46.8% | Reduced |
| J.P. Marvel Investment Advisors, LLC | 7,855 | $3.56M | 0.49% | 00.0% | Unchanged |
| Notis-McConarty Edward | 7,854 | $3.56M | 1.65% | +50+0.6% | Added |
| Baldwin Brothers Inc | 7,824 | $3.55M | 0.23% | −120−1.5% | Reduced |
| Vestmark Advisory Solutions, Inc. | 7,822 | $3.55M | 0.05% | −1,606−17.0% | Reduced |
| Brown Advisory Inc | 7,774 | $3.52M | 0.00% | −320−4.0% | Reduced |
| Johnson Investment Counsel Inc | 7,726 | $3.50M | 0.03% | −4−0.1% | Reduced |
| Bessemer Group Inc | 7,592 | $3.44M | 0.01% | −867−10.2% | Reduced |
| Transamerica Financial Advisors, Inc. | 7,584 | $3.44M | 0.29% | −131−1.7% | Reduced |
| Cresset Asset Management, LLC | 7,555 | $3.43M | 0.01% | −37−0.5% | Reduced |
| Graphene Investments SAS | 7,500 | $3.40M | 2.13% | −800−9.6% | Reduced |
| Marex Group plc | 7,442 | $3.37M | 0.04% | −298−3.9% | Reduced |
| EagleClaw Capital Managment, LLC | 7,385 | $3.35M | 0.48% | 00.0% | Unchanged |
| Central Trust Co | 7,363 | $3.34M | 0.07% | −1,030−12.3% | Reduced |
| CWM, LLC | 7,343 | $3.33M | 0.01% | +1,401+23.6% | Added |
| Stenger Family Office, LLC | 7,323 | $3.32M | 0.69% | −3,398−31.7% | Reduced |
| Codex Capital Asset Management L.L.C. | 7,320 | $3.32M | 1.21% | +70+1.0% | Added |
| SummitTX Capital, L.P. | 7,231 | $3.28M | 0.10% | −724−9.1% | Reduced |
| Freemont Management S.A. | 7,200 | $3.26M | 0.64% | +4,800+200.0% | Added |
| Hantz Financial Services, Inc. | 7,191 | $3.26M | 0.05% | +961+15.4% | Added |
| BNP Paribas | 7,139 | $3.24M | 0.09% | +1,798+33.7% | Added |
| CIBC Private Wealth Group, LLC | 7,087 | $3.21M | 0.01% | +289+4.3% | Added |
| Dempze Nancy E | 7,058 | $3.20M | 1.67% | −194−2.7% | Reduced |
| Elefante Mark B | 7,015 | $3.18M | 1.95% | +352+5.3% | Added |
| RSM US Wealth Management LLC | 7,008 | $3.18M | 0.04% | +1,154+19.7% | Added |
| Glenview Trust Co | 7,005 | $3.18M | 0.05% | +24+0.3% | Added |
| Commerce Bank | 6,999 | $3.17M | 0.02% | +67+1.0% | Added |
| Delaney Dennis R | 6,969 | $3.16M | 1.59% | −79−1.1% | Reduced |
| Associated Banc-Corp | 6,947 | $3.15M | 0.08% | −171−2.4% | Reduced |
| Diversify Advisory Services, LLC | 7,127 | $3.15M | 0.10% | −183−2.5% | Reduced |
| Securian Asset Management, Inc | 6,899 | $3.13M | 0.12% | −5,417−44.0% | Reduced |
| North Star Asset Management Inc | 6,859 | $3.11M | 0.13% | −24−0.3% | Reduced |
| RDA Financial Network | 6,839 | $3.10M | 0.75% | +130+1.9% | Added |
| MUFG Securities Americas Inc. | 6,835 | $3.10M | 0.19% | −79−1.1% | Reduced |
| Wahed Invest LLC | 6,771 | $3.07M | 0.40% | −29−0.4% | Reduced |
| Kentucky Retirement Systems Insurance Trust Fund | 6,768 | $3.07M | 0.20% | 00.0% | Unchanged |
| Edgestream Partners, L.P. | 6,703 | $3.04M | 0.09% | −1,043−13.5% | Reduced |
| Thompson Siegel & Walmsley LLC | 6,698 | $3.04M | 0.05% | −105−1.5% | Reduced |
| Kinneret Advisory, LLC | 6,681 | $3.03M | 0.26% | −183−2.7% | Reduced |
| Leavell Investment Management, Inc. | 6,645 | $3.01M | 0.13% | −340−4.9% | Reduced |
| Channel Wealth LLC | 6,606 | $2.99M | 0.76% | −3,953−37.4% | Reduced |
| Vision Capital Management, Inc. | 6,595 | $2.99M | 0.36% | +29+0.4% | Added |
| Atomi Financial Group, Inc. | 6,541 | $2.97M | 0.09% | +4,157+174.4% | Added |
| Baird Financial Group, Inc. | 6,511 | $2.95M | 0.00% | −659−9.2% | Reduced |
| Condor Capital Management | 6,487 | $2.94M | 0.24% | −20−0.3% | Reduced |
| Canada Post Corp Registered Pension Plan | 6,474 | $2.94M | 0.11% | +2,420+59.7% | Added |
| Camden Capital, LLC | 6,439 | $2.92M | 0.18% | +941+17.1% | Added |
| Boomfish Wealth Group, LLC | 6,410 | $2.91M | 1.55% | −237−3.6% | Reduced |
| South Dakota Investment Council | 6,400 | $2.90M | 0.06% | −480−7.0% | Reduced |
| Resources Investment Advisors, LLC. | 6,392 | $2.90M | 0.03% | +4,898+327.8% | Added |
| Principal Securities, Inc. | 6,319 | $2.86M | 0.04% | −518−7.6% | Reduced |
| Nikko Asset Management Americas, Inc. | 6,314 | $2.86M | 0.03% | −588−8.5% | Reduced |
| Westview Management dba Westview Investment Advisors | 6,284 | $2.85M | 1.36% | +6,284 | New |
| B&L Asset Management LLC | 6,237 | $2.83M | 1.27% | +188+3.1% | Added |
| First National Bank of Mount Dora, Trust Investment Services | 6,212 | $2.82M | 0.62% | +37+0.6% | Added |
| Griffin Asset Management, Inc. | 6,195 | $2.81M | 0.30% | −25−0.4% | Reduced |
| Kovack Advisors, Inc. | 6,191 | $2.81M | 0.13% | +5,044+439.8% | Added |
| Aureus Asset Management, LLC | 6,142 | $2.78M | 0.18% | +4,324+237.8% | Added |
| Univest Financial Corp | 6,097 | $2.76M | 0.15% | −1,267−17.2% | Reduced |
| HighPoint Advisor Group LLC | 6,089 | $2.76M | 0.06% | +1,585+35.2% | Added |
| Meeder Advisory Services, Inc. | 6,065 | $2.75M | 0.12% | +153+2.6% | Added |
| Perigon Wealth Management, LLC | 6,044 | $2.74M | 0.05% | −64−1.0% | Reduced |
| Hall Laurie J Trustee | 6,030 | $2.73M | 0.91% | +80+1.3% | Added |
| Freedom Day Solutions, LLC | 6,027 | $2.73M | 0.74% | +213+3.7% | Added |
| Coldstream Capital Management Inc | 6,002 | $2.72M | 0.04% | −404−6.3% | Reduced |
| Cohen Klingenstein LLC | 6,000 | $2.72M | 0.08% | 00.0% | Unchanged |
| DCF Advisers, LLC | 6,000 | $2.72M | 0.90% | +6,000 | New |
| Plato Investment Management Ltd | 5,935 | $2.70M | 0.18% | −91−1.5% | Reduced |
| Harbour Capital Advisors, LLC | 5,933 | $2.68M | 0.55% | −248−4.0% | Reduced |
| Bokf, NA | 5,867 | $2.66M | 0.04% | −1,171−16.6% | Reduced |
| Illumine Investment Management, LLC | 5,820 | $2.64M | 1.92% | −6−0.1% | Reduced |
| RMR Wealth Builders | 5,789 | $2.62M | 0.21% | +466+8.8% | Added |
| Nemes Rush Group LLC | 5,737 | $2.60M | 0.24% | −13−0.2% | Reduced |
| TD Waterhouse Canada Inc. | 5,731 | $2.60M | 0.02% | +134+2.4% | Added |
| GAMMA Investing LLC | 5,714 | $2.59M | 0.13% | +1,082+23.4% | Added |
| Tudor Investment Corp Et Al | 5,641 | $2.56M | 0.01% | −45,733−89.0% | Reduced |
| Venturi Wealth Management, LLC | 5,630 | $2.55M | 0.11% | −158−2.7% | Reduced |
| V-Square Quantitative Management LLC | 5,624 | $2.55M | 0.27% | +5,624 | New |
| Wedbush Securities Inc | 5,561 | $2.52M | 0.07% | −589−9.6% | Reduced |
| MASTERINVEST Kapitalanlage GmbH | 5,544 | $2.52M | 0.24% | 00.0% | Unchanged |