Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Apollon Wealth Management, LLC | 29,195 | $13.2M | 0.23% | −171−0.6% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 29,189 | $13.2M | 0.20% | +2,405+9.0% | Added |
| Oregon Public Employees Retirement Fund | 29,044 | $13.2M | 0.17% | −241−0.8% | Reduced |
| CAPROCK Group, Inc. | 29,023 | $13.2M | 0.28% | +3,807+15.1% | Added |
| Profund Advisors LLC | 28,818 | $13.1M | 0.40% | +2,423+9.2% | Added |
| Intech Investment Management LLC | 28,530 | $12.9M | 0.12% | −5,831−17.0% | Reduced |
| OP Asset Management Ltd | 28,452 | $12.9M | 0.16% | +164+0.6% | Added |
| Atria Investments LLC | 28,261 | $12.8M | 0.15% | +2,342+9.0% | Added |
| Massmutual Trust Co FSB | 27,914 | $12.7M | 0.33% | −581−2.0% | Reduced |
| Shelter Mutual Insurance Co | 27,600 | $12.5M | 2.79% | 00.0% | Unchanged |
| Avanza Fonder AB | 27,585 | $12.5M | 0.32% | +532+2.0% | Added |
| Bridgewater Associates, LP | 27,488 | $12.5M | 0.05% | −10,836−28.3% | Reduced |
| Mutual of America Capital Management LLC | 27,197 | $12.3M | 0.13% | −549−2.0% | Reduced |
| Bogart Wealth, LLC | 27,177 | $12.3M | 0.49% | +1,028+3.9% | Added |
| Americana Partners, LLC | 27,133 | $12.3M | 0.34% | +2,665+10.9% | Added |
| Fagan Associates, Inc. | 26,566 | $12.0M | 1.61% | +260+1.0% | Added |
| Bender Robert & Associates | 26,463 | $12.0M | 2.49% | +133+0.5% | Added |
| Generate Investment Management Ltd | 26,334 | $11.9M | 0.54% | +600+2.3% | Added |
| CCM Investment Advisers LLC | 26,249 | $11.9M | 1.14% | −2,060−7.3% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 26,100 | $11.8M | 0.08% | +435+1.7% | Added |
| ASR Vermogensbeheer N.V. | 26,059 | $11.8M | 0.14% | −235−0.9% | Reduced |
| LVM Capital Management Ltd | 25,775 | $11.7M | 1.09% | −65−0.3% | Reduced |
| Meritage Portfolio Management | 25,438 | $11.5M | 0.77% | −502−1.9% | Reduced |
| Pinnacle Associates Ltd | 25,238 | $11.4M | 0.15% | −129−0.5% | Reduced |
| Fisher Asset Management, LLC | 25,218 | $11.4M | 0.00% | −741−2.9% | Reduced |
| Allianz SE | 25,181 | $11.4M | 0.15% | +1,260+5.3% | Added |
| Biondo Investment Advisors, LLC | 25,140 | $11.4M | 1.38% | +65+0.3% | Added |
| Jain Global LLC | 24,978 | $11.3M | 0.11% | +24,978 | New |
| Advisors Asset Management, Inc. | 24,713 | $11.2M | 0.19% | −1,213−4.7% | Reduced |
| Banque Pictet & Cie SA | 24,328 | $11.0M | 0.11% | +15,470+174.6% | Added |
| Norinchukin Bank, The | 24,203 | $11.0M | 0.13% | +2,177+9.9% | Added |
| Eurizon SLJ Capital Ltd | 24,156 | $11.0M | 4.34% | +24,156 | New |
| Capital Group Private Client Services, Inc. | 23,852 | $10.8M | 0.17% | −1,022−4.1% | Reduced |
| Yousif Capital Management, LLC | 24,304 | $10.7M | 0.12% | −1,358−5.3% | Reduced |
| Motley Fool Asset Management LLC | 23,603 | $10.7M | 0.42% | +5,905+33.4% | Added |
| Somerville Kurt F | 23,327 | $10.6M | 1.79% | +684+3.0% | Added |
| HealthInvest Partners AB | 22,984 | $10.4M | 3.32% | +5,218+29.4% | Added |
| Warren Averett Asset Management, LLC | 22,732 | $10.3M | 0.08% | +2,484+12.3% | Added |
| Ieq Capital, LLC | 22,524 | $10.2M | 0.03% | +16,073+249.2% | Added |
| Kennedy Capital Management, Inc. | 22,414 | $10.2M | 0.22% | +234+1.1% | Added |
| Exencial Wealth Advisors, LLC | 22,382 | $10.1M | 0.32% | +20,882+1,392.1% | Added |
| Telos Capital Management, Inc. | 22,376 | $10.1M | 0.95% | +1,188+5.6% | Added |
| Cary Street Partners Financial LLC | 22,355 | $10.1M | 0.25% | −568−2.5% | Reduced |
| Investment Management Corp of Ontario | 22,300 | $10.1M | 0.13% | +7,065+46.4% | Added |
| Acadian Asset Management LLC | 22,210 | $10.1M | 0.02% | +21,953+8,542.0% | Added |
| Fifth Third Bancorp | 22,158 | $10.0M | 0.03% | −65−0.3% | Reduced |
| Wiley Bros.-Aintree Capital, LLC | 22,138 | $10.0M | 0.05% | −5,811−20.8% | Reduced |
| EULAV Asset Management | 22,000 | $9.97M | 0.27% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 21,511 | $9.75M | 0.04% | −377−1.7% | Reduced |
| Modera Wealth Management, LLC | 21,275 | $9.65M | 0.11% | −578−2.6% | Reduced |
| Grandfield & Dodd, LLC | 21,231 | $9.63M | 0.55% | +1,411+7.1% | Added |
| Camden National Bank | 20,968 | $9.51M | 1.31% | +76+0.4% | Added |
| Capital Group Investment Management Pte. Ltd. | 20,865 | $9.46M | 1.54% | −5,421−20.6% | Reduced |
| Sig Brokerage, LP | 20,864 | $9.46M | 3.18% | −5,526−20.9% | Reduced |
| AIMZ Investment Advisors, LLC | 20,261 | $9.19M | 2.63% | −100−0.5% | Reduced |
| Heirloom Wealth Management | 20,199 | $9.16M | 2.12% | +233+1.2% | Added |
| Fiduciary Trust Co | 20,032 | $9.08M | 0.10% | −1,889−8.6% | Reduced |
| UniSuper Management Pty Ltd | 19,992 | $9.06M | 0.05% | −503−2.5% | Reduced |
| Mercer Global Advisors Inc | 23,822 | $8.99M | 0.01% | +5,038+26.8% | Added |
| Allstate Corp | 19,095 | $8.66M | 0.12% | +9,803+105.5% | Added |
| Abn Amro Investment Solutions | 19,070 | $8.65M | 0.13% | −106,890−84.9% | Reduced |
| GW Henssler & Associates Ltd | 18,834 | $8.54M | 0.41% | −3,957−17.4% | Reduced |
| Azimuth Capital Investment Management LLC | 18,742 | $8.50M | 0.30% | −1,606−7.9% | Reduced |
| Pinnacle Financial Partners, Inc. | 18,588 | $8.43M | 0.06% | +18,588 | New |
| Generali Asset Management SPA SGR | 18,538 | $8.40M | 0.17% | −5,031−21.3% | Reduced |
| QRG Capital Management, Inc. | 18,396 | $8.34M | 0.09% | +2,563+16.2% | Added |
| Landscape Capital Management, L.L.C. | 18,054 | $8.18M | 0.55% | +7,570+72.2% | Added |
| Mizuho Securities USA LLC | 18,474 | $8.01M | 0.13% | −200−1.1% | Reduced |
| Nia Impact Advisors, LLC | 17,638 | $8.00M | 2.68% | +1,705+10.7% | Added |
| Ossiam | 17,594 | $7.98M | 0.16% | +4,654+36.0% | Added |
| Sterling Capital Management LLC | 17,542 | $7.95M | 0.13% | +64+0.4% | Added |
| Simplify Asset Management Inc. | 17,492 | $7.93M | 0.13% | +16,267+1,327.9% | Added |
| Jacobs Levy Equity Management, Inc | 17,416 | $7.90M | 0.03% | −7,533−30.2% | Reduced |
| Steward Partners Investment Advisory, LLC | 17,364 | $7.87M | 0.04% | −9,997−36.5% | Reduced |
| GWM Advisors LLC | 17,335 | $7.86M | 0.03% | +5,617+47.9% | Added |
| Broderick Brian C | 17,202 | $7.80M | 1.47% | −49−0.3% | Reduced |
| Toroso Investments, LLC | 16,838 | $7.63M | 0.03% | +2,206+15.1% | Added |
| Oppenheimer Asset Management Inc. | 16,720 | $7.58M | 0.09% | −8,740−34.3% | Reduced |
| Fulcrum Capital LLC | 16,616 | $7.53M | 1.51% | +360+2.2% | Added |
| Trifecta Capital Advisors, LLC | 16,497 | $7.48M | 1.11% | +664+4.2% | Added |
| Envestnet Portfolio Solutions, Inc. | 16,469 | $7.47M | 0.03% | −1,752−9.6% | Reduced |
| LMR Partners LLP | 16,468 | $7.47M | 0.07% | +367+2.3% | Added |
| Aptus Capital Advisors, LLC | 16,442 | $7.45M | 0.06% | +687+4.4% | Added |
| Madison Asset Management, LLC | 16,435 | $7.45M | 0.09% | +234+1.4% | Added |
| Leuthold Group, LLC | 16,407 | $7.44M | 0.80% | +3,564+27.8% | Added |
| Kentucky Retirement Systems | 16,147 | $7.32M | 0.20% | 00.0% | Unchanged |
| Blair William & Co | 16,090 | $7.29M | 0.02% | −1,900−10.6% | Reduced |
| Boston Common Asset Management, LLC | 16,081 | $7.29M | 0.44% | −24,818−60.7% | Reduced |
| Silvercrest Asset Management Group LLC | 16,028 | $7.27M | 0.05% | −931−5.5% | Reduced |
| Ethic Inc. | 15,983 | $7.25M | 0.11% | +2,012+14.4% | Added |
| Prudential PLC | 15,771 | $7.15M | 0.06% | −797−4.8% | Reduced |
| Anderson Hoagland & Co | 15,734 | $7.13M | 0.61% | −33−0.2% | Reduced |
| Third View Private Wealth, LLC | 15,717 | $7.13M | 0.96% | +15,717 | New |
| Prevail Innovative Wealth Advisors, LLC | 15,613 | $7.08M | 1.27% | +413+2.7% | Added |
| Bleakley Financial Group, LLC | 15,594 | $7.07M | 0.12% | +15,594 | New |
| Baldwin Investment Management, LLC | 15,554 | $7.05M | 0.80% | −194−1.2% | Reduced |
| Janney Capital Management LLC | 15,542 | $7.05M | 0.44% | −165−1.1% | Reduced |
| Omers Administration Corp | 15,479 | $7.02M | 0.05% | +1,725+12.5% | Added |
| Torray LLC | 15,466 | $7.01M | 1.00% | −789−4.9% | Reduced |
| Puzo Michael J | 15,371 | $6.97M | 1.90% | −130−0.8% | Reduced |