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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Twin Capital Management Inc2,933$1.18M0.13%−2,826−49.1%Reduced
NorthRock Partners, LLC2,925$1.18M0.04%−377−11.4%Reduced
Schechter Investment Advisors, LLC2,920$1.18M0.09%+563+23.9%Added
Prosperity Consulting Group, LLC2,919$1.18M0.09%−661−18.5%Reduced
Graypoint LLC2,902$1.17M0.07%−104−3.5%Reduced
Brown Brothers Harriman & Co2,842$1.14M0.01%+364+14.7%Added
Lake Street Advisors Group, LLC2,838$1.14M0.05%+222+8.5%Added
L & S Advisors Inc2,811$1.13M0.12%−406−12.6%Reduced
Vise Technologies, Inc.2,809$1.13M0.09%+1,646+141.5%Added
1858 Wealth Management, LLC2,784$1.12M0.89%+165+6.3%Added
IFP Advisors, Inc2,756$1.11M0.04%+909+49.2%Added
Park Circle Co2,764$1.11M1.01%00.0%Unchanged
Teamwork Financial Advisors, LLC2,717$1.09M0.14%−7,378−73.1%Reduced
Resources Investment Advisors, LLC.2,700$1.09M0.01%−117−4.2%Reduced
Headinvest, LLC2,695$1.09M0.20%−173−6.0%Reduced
MBM Wealth Consultants, LLC2,664$1.08M0.32%+124+4.9%Added
Cigna Investments Inc2,657$1.07M0.19%−14−0.5%Reduced
West Family Investments, Inc.2,652$1.07M0.37%−12−0.5%Reduced
Strategy Asset Managers LLC2,614$1.05M0.20%−95−3.5%Reduced
Towarzystwo Funduszy Inwestycyjnych Pzu SA2,585$1.04M0.34%−15−0.6%Reduced
Smartleaf Asset Management LLC2,604$1.04M0.11%+381+17.1%Added
Sculati Wealth Management, LLC2,556$1.03M0.41%+25+1.0%Added
Dorsey & Whitney Trust CO LLC2,554$1.03M0.06%+229+9.8%Added
Legacy Financial Advisors, Inc.2,552$1.03M0.17%+104+4.2%Added
Evergreen Capital Management LLC2,539$1.02M0.03%−101−3.8%Reduced
XTX Topco Ltd2,530$1.02M0.09%+2,530New
Mitsubishi UFJ Asset Management (UK) Ltd.2,500$1.01M0.44%+2,500New
Westport Asset Management Inc2,500$1.01M0.48%+2,500New
Quadrant Capital Group LLC2,497$1.01M0.07%+12+0.5%Added
Baader Bank INC2,476$996.7K0.09%+38+1.6%Added
Jones Financial Companies LLLP2,468$993.9K0.00%+1,062+75.5%Added
GraniteShares Advisors LLC2,464$992.3K0.63%−219−8.2%Reduced
Pallas Capital Advisors LLC2,461$991.0K0.04%+75+3.1%Added
Advisory Resource Group2,461$991.0K0.21%+491+24.9%Added
Callan Family Office, LLC2,450$986.6K0.06%+2,450New
Fort Sheridan Advisors LLC2,424$976.1K0.14%+386+18.9%Added
Johnson Financial Group, Inc.2,110$974.1K0.05%−5,283−71.5%Reduced
Farther Finance Advisors, LLC2,409$970.3K0.04%+107+4.6%Added
NVWM, LLC2,384$960.0K0.24%−23−1.0%Reduced
Syon Capital LLC2,360$950.4K0.09%−157−6.2%Reduced
LGT Group Foundation2,334$939.9K0.01%+129+5.9%Added
Sigma Planning Corp2,331$938.6K0.03%−415−15.1%Reduced
Alpine Woods Capital Investors, LLC2,330$938.3K0.18%−2,000−46.2%Reduced
Brookstone Capital Management2,320$934.3K0.01%−2−0.1%Reduced
Sagespring Wealth Partners, LLC2,296$924.8K0.02%+2,296New
Guidance Capital, Inc2,101$923.6K0.28%+395+23.2%Added
Hohimer Wealth Management, LLC2,292$923.0K0.17%−28−1.2%Reduced
U.S. Capital Wealth Advisors, LLC2,277$916.9K0.03%−941−29.2%Reduced
My Legacy Advisors, LLC2,151$912.6K0.35%−76−3.4%Reduced
Portside Wealth Group, LLC2,266$912.5K0.15%+261+13.0%Added
Principal Street Partners, LLC2,258$909.3K0.18%−752−25.0%Reduced
Icon Wealth Advisors, LLC2,252$906.9K0.07%−151−6.3%Reduced
Boston Financial Mangement LLC2,244$903.7K0.03%00.0%Unchanged
Impact Capital Partners LLC2,244$903.7K0.32%+2,244New
Simon Quick Advisors, LLC2,236$900.4K0.05%+24+1.1%Added
Independent Advisor Alliance2,228$897.4K0.01%+1,054+89.8%Added
Kane Investment Management, Inc.2,221$894.4K0.50%+2,221New
Wealthedge Investment Advisors, LLC2,221$894.4K0.40%+2,221New
First Horizon Advisors, Inc.2,199$885.5K0.02%+36+1.7%Added
McAdam, LLC2,195$883.9K0.05%−441−16.7%Reduced
Aureus Asset Management, LLC2,186$880.3K0.06%00.0%Unchanged
Peapack Gladstone Financial Corp2,185$879.0K0.01%−10.0%Reduced
InTrack Investment Management Inc2,132$877.5K0.61%+710+49.9%Added
Atomi Financial Group, Inc.2,179$877.4K0.04%+262+13.7%Added
Cravens & Co Advisors, LLC2,162$870.6K0.66%−46−2.1%Reduced
Bristlecone Advisors, LLC2,150$865.8K0.07%00.0%Unchanged
Mitchell & Pahl Private Wealth, LLC2,149$865.4K0.40%−30−1.4%Reduced
Csenge Advisory Group2,144$863.4K0.05%−828−27.9%Reduced
Acadian Asset Management LLC2,145$860.0K0.00%−3,598−62.7%Reduced
Presilium Private Wealth, LLC2,124$855.3K0.20%−6−0.3%Reduced
Capital Advisors Wealth Management, LLC2,103$846.9K0.15%+116+5.8%Added
Ashton Thomas Private Wealth, LLC2,087$840.4K0.03%−204−8.9%Reduced
Formidable Asset Management, LLC2,087$840.4K0.14%−123−5.6%Reduced
Concurrent Investment Advisors, LLC2,072$834.4K0.02%00.0%Unchanged
Humankind Investments LLC2,067$832.4K0.21%+152+7.9%Added
1248 Management, LLC2,065$831.6K0.36%+2,065New
Stevens Capital Management LP2,058$829.0K0.33%+2,058New
Future Fund LLC2,052$826.3K2.36%+350+20.6%Added
Prossimo Advisors, LLC2,049$825.0K0.60%−38−1.8%Reduced
Wrapmanager Inc2,048$824.7K0.21%−245−10.7%Reduced
Whittier Trust Co2,045$823.5K0.01%+512+33.4%Added
Phoenix Holdings Ltd.2,025$815.6K0.01%−256−11.2%Reduced
Allegheny Financial Group LTD2,019$813.1K0.21%−21−1.0%Reduced
Veracity Capital LLC2,019$813.1K0.30%+401+24.8%Added
Pflug Koory, LLC2,018$812.6K0.41%+79+4.1%Added
Qtron Investments LLC2,016$811.8K0.11%−1,115−35.6%Reduced
Monetta Financial Services Inc2,000$805.4K0.65%00.0%Unchanged
Knott David M Jr2,000$805.4K0.29%00.0%Unchanged
Centaurus Financial, Inc.1,995$803.0K0.05%+137+7.4%Added
Scientech Research LLC1,990$801.4K0.23%−1,507−43.1%Reduced
Gsa Capital Partners LLP1,989$801.0K0.06%+1,989New
Malaga Cove Capital, LLC1,989$801.0K0.31%+1,989New
BOK Financial Private Wealth, Inc.1,983$798.6K0.06%−374−15.9%Reduced
IFG Advisory, LLC1,982$798.2K0.05%+1,982New
Holt Capital Advisors, L.L.C. dba Holt Capital Partners, L.P.1,968$792.5K0.12%−5−0.3%Reduced
Dana Investment Advisors, Inc.1,967$792.1K0.03%−21−1.1%Reduced
Annis Gardner Whiting Capital Advisors, LLC1,944$782.8K0.22%00.0%Unchanged
Lecap Asset Management Ltd1,944$782.8K0.21%+1,944New
Spears Abacus Advisors LLC1,941$781.6K0.02%+3+0.2%Added
Sig Brokerage, LP1,938$780.4K0.37%+1,938New