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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
AustralianSuper Pty Ltd219,075$88.2M0.42%−7,299−3.2%Reduced
Davenport & Co LLC218,068$87.6M0.51%−1,641−0.7%Reduced
Truist Financial Corp211,804$85.3M0.13%+1,885+0.9%Added
Adage Capital Partners GP, L.L.C.209,239$84.3M0.15%−137,116−39.6%Reduced
Korea Investment CORP207,108$83.4M0.20%−14,438−6.5%Reduced
DnB Asset Management AS200,942$80.9M0.35%+19,289+10.6%Added
Welch & Forbes LLC197,781$79.6M1.02%+1,162+0.6%Added
Carmignac Gestion197,466$79.5M1.27%−13,056−6.2%Reduced
Marshall Wace, LLP194,000$78.1M0.10%−50,000−20.5%Reduced
First Trust Advisors LP192,786$77.6M0.07%−382,246−66.5%Reduced
LPL Financial LLC191,053$76.9M0.03%+1,340+0.7%Added
Mirae Asset Global ETFs Holdings Ltd.189,260$76.2M0.16%+567+0.3%Added
Federated Hermes, Inc.189,075$76.1M0.17%−2,864−1.5%Reduced
Vontobel Holding Ltd.188,949$76.1M0.26%+75,653+66.8%Added
Bowen Hanes & Co Inc180,624$72.7M1.95%+1,740+1.0%Added
Polar Capital Holdings Plc175,000$70.5M0.39%00.0%Unchanged
Birch Hill Investment Advisors LLC172,821$69.6M3.24%+4,664+2.8%Added
Mitsubishi UFJ Trust & Banking Corp171,606$69.1M0.16%−13,507−7.3%Reduced
Skandinaviska Enskilda Banken AB (publ)171,034$68.3M0.31%−14,251−7.7%Reduced
Capital International Sarl168,592$67.9M1.57%+25,544+17.9%Added
Prudential Financial Inc168,138$67.7M0.09%−42,095−20.0%Reduced
Danske Bank A/S162,303$65.4M0.20%−16,124−9.0%Reduced
Schroder Investment Management Group163,628$65.3M0.06%−42,151−20.5%Reduced
Citadel Advisors LLC162,181$65.3M0.06%+111,949+222.9%Added
Van Eck Associates Corp159,269$64.1M0.08%+7,841+5.2%Added
Aviva PLC155,490$62.6M0.16%+30,650+24.6%Added
Provident Investment Management, Inc.155,066$62.4M5.96%−439−0.3%Reduced
National Bank of Canada154,800$62.3M0.08%−75,698−32.8%Reduced
State of Wisconsin Investment Board152,240$61.3M0.16%−1,939−1.3%Reduced
OrbiMed Advisors LLC151,000$60.8M1.26%00.0%Unchanged
Manning & Napier Advisors LLC150,126$60.5M0.69%−5,635−3.6%Reduced
Baillie Gifford & Co149,838$60.3M0.05%+9,258+6.6%Added
Nomura Asset Management Co Ltd149,799$60.3M0.18%−5,095−3.3%Reduced
Woodline Partners LP149,418$60.2M0.41%+16,653+12.5%Added
Cookson Peirce & Co Inc147,780$59.5M2.70%−7,301−4.7%Reduced
Congress Asset Management Co147,149$59.3M0.40%−41,431−22.0%Reduced
Lansforsakringar Fondforvaltning AB (publ)144,708$58.3M0.33%+144,708New
Caisse de Depot Et Placement du Quebec141,717$57.1M0.12%−230,252−61.9%Reduced
Colony Group, LLC141,112$56.8M0.15%+18,187+14.8%Added
AXA S.A.140,790$56.7M0.17%−3,620−2.5%Reduced
Abn Amro Investment Solutions140,237$56.5M1.05%+130,033+1,274.3%Added
Tredje AP-fonden137,452$55.4M0.50%+7,978+6.2%Added
Asset Management One Co.,Ltd.135,283$55.3M0.19%+96+0.1%Added
Balyasny Asset Management LLC135,823$54.7M0.13%+81,351+149.3%Added
Guggenheim Capital LLC135,695$54.6M0.45%−3,596−2.6%Reduced
Storebrand Asset Management AS135,051$54.4M0.17%−5,916−4.2%Reduced
Raiffeisen Bank International AG133,898$53.5M0.81%+133,898New
Susquehanna International Group, LLP130,405$52.5M0.08%+84,357+183.2%Added
British Columbia Investment Management Corp127,324$51.3M0.31%+84,266+195.7%Added
PFM Health Sciences, LP126,989$51.1M3.90%−21,863−14.7%Reduced
Stifel Financial Corp124,844$50.3M0.05%+30,512+32.3%Added
Capital International Inc124,134$50.0M0.59%+13,781+12.5%Added
ABN AMRO Bank N.V.124,052$49.5M0.67%+7,383+6.3%Added
Mariner, LLC122,417$49.3M0.08%−1,077−0.9%Reduced
Employees Retirement System of Texas121,600$49.0M0.42%+3,600+3.1%Added
Mirae Asset Global Investments Co., Ltd.119,549$48.4M0.20%+17,264+16.9%Added
KBC Group NV119,429$48.1M0.13%+22,702+23.5%Added
Treasurer of the State of North Carolina116,793$47.0M0.18%+520+0.4%Added
Public Employees Retirement System of Ohio115,847$46.7M0.16%−6,126−5.0%Reduced
Hardman Johnston Global Advisors LLC114,664$46.2M1.91%−245−0.2%Reduced
CI Private Wealth, LLC113,146$45.2M0.07%−16,119−12.5%Reduced
Capital International Ltd110,571$44.5M1.82%+10,966+11.0%Added
Toronto Dominion Bank107,834$43.4M0.08%−26,368−19.6%Reduced
Teacher Retirement System of Texas104,895$42.2M0.15%+22,165+26.8%Added
Rockefeller Capital Management L.P.98,789$39.8M0.10%+28,240+40.0%Added
Allspring Global Investments Holdings, LLC96,626$39.2M0.06%−139,700−59.1%Reduced
Credit Agricole S A96,715$38.9M0.13%−1,792−1.8%Reduced
State of New Jersey Common Pension Fund D95,267$38.4M0.15%00.0%Unchanged
LMR Partners LLP93,801$37.8M0.66%+93,801New
FIL Ltd93,273$37.6M0.04%+86,242+1,226.6%Added
State of Tennessee, Treasury Department93,189$37.5M0.14%−7,333−7.3%Reduced
Janney Montgomery Scott LLC92,192$37.1M0.10%−35,233−27.6%Reduced
Rafferty Asset Management, LLC90,219$36.3M0.13%+3,910+4.5%Added
Man Group plc88,726$35.7M0.11%+37,008+71.6%Added
Thrivent Financial for Lutherans87,900$35.6M0.07%−3,775−4.1%Reduced
Corebridge Financial, Inc.88,046$35.5M0.19%+112+0.1%Added
Banco Bilbao Vizcaya Argentaria, S.A.87,796$35.4M0.37%−4,531−4.9%Reduced
KLP Kapitalforvaltning AS86,941$35.0M0.17%+86,941New
Epoch Investment Partners, Inc.86,477$34.8M0.17%−8,104−8.6%Reduced
Resona Asset Management Co.,Ltd.86,227$34.8M0.21%−7,976−8.5%Reduced
CIBC Asset Management Inc84,491$34.0M0.11%+4,389+5.5%Added
Country Trust Bank83,602$33.7M0.84%−10,489−11.1%Reduced
B. Metzler seel. Sohn & Co. AG80,759$32.4M0.33%+40,766+101.9%Added
Wealth Enhancement Advisory Services, LLC80,189$32.3M0.06%−21,702−21.3%Reduced
Assetmark, Inc79,865$32.2M0.09%−124,206−60.9%Reduced
GuoLine Advisory Pte Ltd79,700$32.1M3.31%00.0%Unchanged
Creative Planning79,470$32.0M0.03%−997−1.2%Reduced
Beacon Investment Advisory Services, Inc.78,824$31.7M1.38%−347−0.4%Reduced
The PNC Financial Services Group, Inc.78,622$31.7M0.02%−807−1.0%Reduced
STRS Ohio78,531$31.6M0.13%−9,807−11.1%Reduced
Jupiter Asset Management Ltd78,166$31.5M0.31%−81,761−51.1%Reduced
Alyeska Investment Group, L.P.77,535$31.2M0.12%+74,182+2,212.4%Added
William Blair Investment Management, LLC77,532$31.2M0.08%+983+1.3%Added
Arizona State Retirement System74,607$30.0M0.18%+673+0.9%Added
MetLife Investment Management73,884$29.8M0.16%+873+1.2%Added
State of Michigan Retirement System72,423$29.2M0.15%−1,200−1.6%Reduced
Healthcare of Ontario Pension Plan Trust Fund72,209$29.1M0.06%+23,144+47.2%Added
Nisa Investment Advisors, LLC70,222$28.3M0.11%−5,128−6.8%Reduced
Voloridge Investment Management, LLC69,712$28.1M0.10%−67,376−49.1%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund68,088$27.4M0.28%−3,900−5.4%Reduced