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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
AMF Pensionsforsakring AB67,757$27.3M0.19%−100,161−59.6%Reduced
C WorldWide Group Holding A/S67,557$27.2M0.33%00.0%Unchanged
Erste Asset Management GmbH65,774$26.5M0.33%+2,260+3.6%Added
Gateway Investment Advisers LLC65,842$26.5M0.30%−719−1.1%Reduced
Daiwa Securities Group Inc.65,728$26.5M0.12%+7,861+13.6%Added
Ossiam64,833$26.1M0.45%+435+0.7%Added
Commonwealth Equity Services, LLC64,120$25.8M0.04%+693+1.1%Added
Teachers Retirement System of the State of Kentucky63,057$25.4M0.22%−33,779−34.9%Reduced
Davidson Investment Advisors61,161$24.6M1.20%+12,631+26.0%Added
Foster Dykema Cabot & Partners, LLC60,864$24.5M1.91%+1,094+1.8%Added
La Banque Postale Asset Management SA59,359$23.9M0.32%+54,646+1,159.5%Added
GF Fund Management Co. Ltd.59,178$23.8M0.52%+59,178New
Nissay Asset Management Corp58,242$23.8M0.15%+2,879+5.2%Added
Forsta Ap-Fonden58,700$23.6M0.17%−1,200−2.0%Reduced
Moody Lynn & Lieberson, LLC57,223$23.0M1.41%−7,984−12.2%Reduced
Edgemoor Investment Advisors, Inc.57,097$23.0M2.03%+92+0.2%Added
Polar Asset Management Partners Inc.57,000$23.0M0.34%+57,000New
Segall Bryant & Hamill, LLC56,235$22.6M0.31%−1,590−2.7%Reduced
J. Safra Sarasin Holding AG55,896$22.5M0.38%−4,246−7.1%Reduced
Czech National Bank55,838$22.5M0.21%+3,260+6.2%Added
Retirement Systems of Alabama55,758$22.5M0.08%−166,947−75.0%Reduced
Atwood & Palmer Inc55,390$22.3M1.53%+1,130+2.1%Added
Twinbeech Capital LP55,249$22.2M0.38%+55,249New
Commonwealth of Pennsylvania Public School Empls Retrmt Sys54,758$22.1M0.14%−1,428−2.5%Reduced
Shelton Capital Management54,631$22.0M0.55%+647+1.2%Added
Cetera Investment Advisers53,957$21.7M0.05%+328+0.6%Added
Federation des caisses Desjardins du Quebec53,236$21.4M0.11%+13,749+34.8%Added
Cullinan Associates Inc53,162$21.4M1.37%−1,500−2.7%Reduced
Amalgamated Bank53,004$21.3M0.18%−3,186−5.7%Reduced
Zacks Investment Management52,653$21.2M0.20%−9,831−15.7%Reduced
Vestcor Inc52,631$21.2M0.70%−12,624−19.3%Reduced
China Universal Asset Management Co., Ltd.52,381$21.1M1.97%+2,962+6.0%Added
Barlow Wealth Partners, Inc.49,710$21.1M2.67%+2,138+4.5%Added
Reynders McVeigh Capital Management, LLC52,254$21.0M1.11%+3,524+7.2%Added
Zurich Insurance Group Ltd51,527$20.7M0.17%−1,735−3.3%Reduced
Aristotle Atlantic Partners, LLC51,251$20.6M0.65%−2,843−5.3%Reduced
Martingale Asset Management L P51,207$20.6M0.50%−2,120−4.0%Reduced
Hallmark Capital Management Inc50,524$20.3M1.52%+50+0.1%Added
Boston Common Asset Management, LLC50,292$20.3M0.59%+26+0.1%Added
Rhenman & Partners Asset Management AB50,000$20.1M2.07%+2,250+4.7%Added
Comerica Bank49,578$20.0M0.08%−4,045−7.5%Reduced
Hemenway Trust Co LLC49,413$19.9M1.61%+9,294+23.2%Added
De Burlo Group Inc48,735$19.6M2.62%−460−0.9%Reduced
IFM Investors Pty Ltd48,731$19.6M0.20%−4,691−8.8%Reduced
HighTower Advisors, LLC48,586$19.6M0.03%−8,656−15.1%Reduced
Xponance, Inc.48,507$19.5M0.18%+539+1.1%Added
Banco Santander, S.A.48,184$19.4M0.23%+32,316+203.7%Added
Sanctuary Advisors, LLC43,831$19.2M0.12%+928+2.2%Added
Illinois Municipal Retirement Fund47,388$19.1M0.27%−16,391−25.7%Reduced
Cumberland Partners Ltd47,326$19.1M1.33%+4,126+9.6%Added
Bank of Nova Scotia47,097$19.0M0.03%−27,573−36.9%Reduced
Varma Mutual Pension Insurance Co46,826$18.9M0.14%−9,100−16.3%Reduced
Castleark Management LLC46,485$18.7M0.65%−36,240−43.8%Reduced
CIBC World Markets Corp46,339$18.7M0.11%+5,665+13.9%Added
Nomura Holdings Inc45,901$18.5M0.10%+5,868+14.7%Added
State of Alaska, Department of Revenue45,785$18.4M0.21%−2,190−4.6%Reduced
Sumitomo Mitsui DS Asset Management Company, Ltd45,669$18.4M0.19%+2,036+4.7%Added
Mackenzie Financial Corp45,632$18.4M0.03%−23,060−33.6%Reduced
Churchill Management Corp45,457$18.3M0.20%+102+0.2%Added
Braun Stacey Associates Inc45,450$18.3M0.68%−6,047−11.7%Reduced
Calamos Advisors LLC45,244$18.2M0.08%00.0%Unchanged
Atalanta Sosnoff Capital, LLC45,202$18.2M0.40%−74,236−62.2%Reduced
USS Investment Management Ltd44,403$17.9M0.13%−2,996−6.3%Reduced
Smith Group Asset Management, LLC43,633$17.6M1.30%−26−0.1%Reduced
NEOS Investment Management LLC43,331$17.4M0.41%+7,732+21.7%Added
W.G. Shaheen & Associates DBA Whitney & Co43,246$17.4M1.83%−160−0.4%Reduced
Groupama Asset Managment43,479$17.4M0.35%+9,149+26.7%Added
Utah Retirement Systems42,903$17.3M0.19%+100+0.2%Added
NewEdge Wealth, LLC41,447$16.7M0.29%+1,297+3.2%Added
Bridger Management, LLC41,050$16.5M8.88%00.0%Unchanged
Wealthfront Advisers LLC41,019$16.5M0.05%+1,819+4.6%Added
iA Global Asset Management Inc.40,862$16.5M0.29%−404−1.0%Reduced
Tweedy, Browne Co LLC40,631$16.4M1.10%−12,969−24.2%Reduced
Steward Partners Investment Advisory, LLC39,808$16.0M0.14%−4,948−11.1%Reduced
CAPROCK Group, Inc.39,184$15.8M0.52%+1,096+2.9%Added
New York Life Investment Management LLC39,060$15.7M0.15%+383+1.0%Added
Pacer Advisors, Inc.38,800$15.6M0.03%+6,359+19.6%Added
Huntington National Bank38,386$15.5M0.11%−843−2.1%Reduced
Burney Co37,767$15.2M0.54%−8,394−18.2%Reduced
Police & Firemen's Retirement System of New Jersey37,636$15.2M0.15%+37,636New
Advisor Group Holdings, Inc.49,303$15.2M0.03%−143−0.3%Reduced
Bailard, Inc.37,415$15.1M0.39%−1,102−2.9%Reduced
Pathstone Holdings, LLC37,353$15.0M0.07%−3,300−8.1%Reduced
Motley Fool Wealth Management, LLC36,461$14.7M0.76%−3,032−7.7%Reduced
MML Investors Services, LLC36,219$14.6M0.05%−11,858−24.7%Reduced
Andra AP-fonden36,100$14.5M0.23%−5,500−13.2%Reduced
Ci Investments Inc.35,868$14.4M0.05%−18,058−33.5%Reduced
Sapient Capital LLC35,796$14.4M0.28%+498+1.4%Added
Meritage Portfolio Management35,739$14.4M0.89%−773−2.1%Reduced
Adams Diversified Equity Fund, Inc.35,100$14.1M0.53%00.0%Unchanged
Two Sigma Investments, LP33,160$13.4M0.03%−127,375−79.3%Reduced
Mutual of America Capital Management LLC32,899$13.2M0.14%−933−2.8%Reduced
Louisiana State Employees Retirement System32,700$13.2M0.25%−1,500−4.4%Reduced
Public Sector Pension Investment Board32,402$13.0M0.06%+21,158+188.2%Added
Dai-Ichi Life Insurance Company, Ltd31,924$12.9M0.36%+5,831+22.3%Added
Lido Advisors, LLC31,606$12.7M0.08%+7,207+29.5%Added
Flputnam Investment Management Co31,443$12.7M0.23%+22,141+238.0%Added
JustInvest LLC31,178$12.6M0.19%−619−1.9%Reduced
McRae Capital Management Inc31,078$12.5M2.45%−802−2.5%Reduced
F/M Investments LLC30,915$12.4M0.46%−11,548−27.2%Reduced