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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,224
+121 vs. Q3 2022
Shares held
237.1M
+549.4K (+0.2%) vs. Q3 2022
Total value
$68.3B
−$59.7M (−0.1%) vs. Q3 2022
New holders
185
438 more added
Sold out
64
440 more reduced

24 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 1,225 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2022: $68.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2022.

Institutions holding VRTX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Nomura Asset Management Co Ltd296,519$85.6M0.50%−22,660−7.1%Reduced
Retirement Systems of Alabama294,834$85.1M0.37%−2,949−1.0%Reduced
Polar Capital Holdings Plc290,000$83.7M0.67%−280−0.1%Reduced
Envestnet Asset Management Inc284,200$82.1M0.04%+14,768+5.5%Added
Great West Life Assurance Co278,324$80.7M0.21%−19,914−6.7%Reduced
Canada Pension Plan Investment Board279,401$80.7M0.14%−1,326,453−82.6%Reduced
Susquehanna International Group, LLP279,001$80.6M0.16%+232,658+502.0%Added
Manning & Napier Group, LLC271,904$78.5M0.97%−4,987−1.8%Reduced
OrbiMed Advisors LLC271,500$78.4M1.50%−101,700−27.3%Reduced
Virginia Retirement Systems Et Al270,200$78.0M0.81%−4,300−1.6%Reduced
ProShare Advisors LLC255,282$73.7M0.26%−26,430−9.4%Reduced
KBC Group NV254,327$73.4M0.36%+352+0.1%Added
BNP Paribas Arbitrage, SA248,321$71.7M0.18%+60,914+32.5%Added
Parnassus Investments240,281$69.4M0.17%−21,686−8.3%Reduced
Mitsubishi UFJ Trust & Banking Corp234,972$67.9M0.18%−8,809−3.6%Reduced
Chevy Chase Trust Holdings, Inc.216,029$62.4M0.27%+59,356+37.9%Added
FIL Ltd215,674$62.3M0.07%−34,019−13.6%Reduced
Hardman Johnston Global Advisors LLC206,727$59.7M2.34%−7,273−3.4%Reduced
Birch Hill Investment Advisors LLC204,323$59.0M3.76%−6,173−2.9%Reduced
Citadel Advisors LLC203,611$58.8M0.07%+189,846+1,379.2%Added
Schroder Investment Management Group199,861$57.7M0.09%+90,908+83.4%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.196,887$56.3M0.15%+18,898+10.6%Added
Twinbeech Capital LP192,626$55.6M1.06%+192,626New
Glenmede Trust Co NA190,703$55.1M0.32%+30,980+19.4%Added
Artisan Partners Limited Partnership188,470$54.4M0.10%−39,234−17.2%Reduced
Welch & Forbes LLC188,171$54.3M0.97%−1,287−0.7%Reduced
Standard Life Aberdeen plc183,816$53.1M0.14%−2,999−1.6%Reduced
Storebrand Asset Management AS181,383$52.4M0.29%+13,716+8.2%Added
Adage Capital Partners GP, L.L.C.179,890$51.9M0.12%−157,273−46.6%Reduced
State of Tennessee, Treasury Department175,386$50.6M0.24%−68,077−28.0%Reduced
Bowen Hanes & Co Inc175,210$50.6M1.79%−5,800−3.2%Reduced
Avidity Partners Management LP172,000$49.7M1.16%−340,800−66.5%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main172,000$49.7M0.09%−5,674−3.2%Reduced
State of Wisconsin Investment Board171,502$49.5M0.16%−7,591−4.2%Reduced
Truist Financial Corp171,444$49.5M0.09%+62,866+57.9%Added
Bank Julius Baer & Co. Ltd, Zurich170,370$49.2M0.34%+162,295+2,009.8%Added
Guggenheim Capital LLC168,959$48.8M0.43%−6,140−3.5%Reduced
LPL Financial LLC165,339$47.7M0.04%+32,264+24.2%Added
Clal Insurance Enterprises Holdings Ltd165,240$47.7M0.72%−47,000−22.1%Reduced
Pinebridge Investments, L.P.163,772$47.3M0.57%+2,683+1.7%Added
Van Eck Associates Corp163,663$47.3M0.12%−11,507−6.6%Reduced
Provident Investment Management, Inc.160,727$46.4M5.50%−1,300−0.8%Reduced
Acadian Asset Management LLC157,441$45.4M0.22%+35,552+29.2%Added
Sofinnova Investments, Inc.156,989$45.3M2.75%+156,989New
Public Employees Retirement System of Ohio156,418$45.2M0.20%+917+0.6%Added
Aviva PLC152,261$44.0M0.22%−18,744−11.0%Reduced
State of New Jersey Common Pension Fund D151,502$43.8M0.17%+1,228+0.8%Added
Federated Hermes, Inc.151,022$43.6M0.12%−5,368−3.4%Reduced
Teachers Retirement System of the State of Kentucky149,187$43.1M0.45%−610.0%Reduced
Armistice Capital, LLC148,000$42.7M1.15%−2,000−1.3%Reduced
Country Trust Bank147,423$42.6M1.26%−940−0.6%Reduced
CI Private Wealth, LLC145,326$42.0M0.15%+145,326New
Ardevora Asset Management LLP142,900$41.3M0.70%+142,900New
Lazard Asset Management LLC142,441$41.1M0.06%−481,400−77.2%Reduced
Teacher Retirement System of Texas141,130$40.8M0.30%−4,984−3.4%Reduced
National Bank of Canada138,169$39.9M0.11%+89,411+183.4%Added
Toronto Dominion Bank136,330$39.3M0.06%+20,190+17.4%Added
Putnam Investments LLC133,972$38.7M0.07%−9,309−6.5%Reduced
Treasurer of the State of North Carolina131,565$38.0M0.23%+5,844+4.6%Added
Jupiter Asset Management Ltd130,515$37.7M0.55%+38,968+42.6%Added
Banco Bilbao Vizcaya Argentaria, S.A.129,492$37.4M0.55%+4,697+3.8%Added
Janney Montgomery Scott LLC128,584$37.1M0.14%+21,258+19.8%Added
AMF Pensionsforsakring AB123,575$35.7M0.41%+34,879+39.3%Added
Mn Services Vermogensbeheer B.V.123,400$35.6M0.40%−18,400−13.0%Reduced
ARK Investment Management LLCSuperinvestorARK Invest122,197$35.3M0.31%−35,248−22.4%Reduced
Cookson Peirce & Co Inc119,115$34.4M2.24%+59,543+100.0%Added
Asset Management One Co.,Ltd.118,935$34.4M0.17%−7,130−5.7%Reduced
Grantham, Mayo, Van Otterloo & Co. LLC117,200$33.8M0.18%+4,200+3.7%Added
Atalanta Sosnoff Capital, LLC112,234$32.4M1.00%−11,420−9.2%Reduced
Natixis Investment Managers International111,300$32.1M2.40%−14,825−11.8%Reduced
Panagora Asset Management Inc110,942$32.0M0.21%+34,885+45.9%Added
Point72 Asset Management, L.P.110,839$32.0M0.12%+3,439+3.2%Added
D. E. Shaw & Co., Inc.110,533$31.9M0.05%−7,720−6.5%Reduced
STRS Ohio109,338$31.6M0.14%−6,357−5.5%Reduced
Mackenzie Financial Corp108,902$31.4M0.05%−9,220−7.8%Reduced
Unigestion Holding SA105,226$30.4M1.61%+8,161+8.4%Added
Bridgewater Associates, LP100,819$29.1M0.16%−63,172−38.5%Reduced
Ossiam96,059$27.7M0.72%+1,765+1.9%Added
Renaissance Group LLC95,604$27.6M1.35%−748−0.8%Reduced
Thrivent Financial for Lutherans95,177$27.5M0.07%−137−0.1%Reduced
Oregon Public Employees Retirement Fund94,845$27.4M0.35%+14,571+18.2%Added
Cubist Systematic Strategies, LLC94,395$27.3M0.23%+8,404+9.8%Added
Colony Group LLC93,995$27.1M0.38%+7,769+9.0%Added
C WorldWide Group Holding A/S93,557$27.0M0.36%00.0%Unchanged
Illinois Municipal Retirement Fund93,366$27.0M0.61%+3,918+4.4%Added
American International Group, Inc.93,288$26.9M0.19%−5,141−5.2%Reduced
Calamos Advisors LLC91,757$26.5M0.13%−16,171−15.0%Reduced
Royal London Asset Management Ltd90,877$26.2M0.12%+4,395+5.1%Added
Worldquant Millennium Advisors LLC88,282$25.5M0.58%+56,520+177.9%Added
Railway Pension Investments Ltd85,400$24.7M0.25%+36,500+74.6%Added
Vestcor Inc84,246$24.3M0.89%+4,524+5.7%Added
Martingale Asset Management L P83,185$24.0M0.47%−2,453−2.9%Reduced
Erste Asset Management GmbH82,130$23.7M0.50%−393−0.5%Reduced
Rhenman & Partners Asset Management AB80,000$23.1M2.41%−16,000−16.7%Reduced
Nisa Investment Advisors, LLC79,530$23.0M0.18%−1,550−1.9%Reduced
Natixis78,478$22.7M0.13%+55,193+237.0%Added
Boston Common Asset Management, LLC77,304$22.3M1.07%+2,027+2.7%Added
MetLife Investment Management76,636$22.1M0.17%−1,447−1.9%Reduced
Beacon Investment Advisory Services, Inc.74,840$21.6M1.11%+423+0.6%Added
SEI Investments Co74,333$21.5M0.05%−37,235−33.4%Reduced