Skip to main content

Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,224
+121 vs. Q3 2022
Shares held
237.1M
+549.4K (+0.2%) vs. Q3 2022
Total value
$68.3B
−$59.7M (−0.1%) vs. Q3 2022
New holders
185
438 more added
Sold out
64
440 more reduced

24 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 1,224 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2022: $68.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2022.

Institutions holding VRTX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
State of Michigan Retirement System72,923$21.1M0.15%−500−0.7%Reduced
Hallmark Capital Management Inc72,247$20.9M1.94%−6,879−8.7%Reduced
Gateway Investment Advisers LLC72,217$20.9M0.26%−4,207−5.5%Reduced
Formuepleje A/S71,712$20.7M1.75%+31,833+79.8%Added
The PNC Financial Services Group, Inc.70,275$20.3M0.02%−2,328−3.2%Reduced
Amalgamated Bank69,909$20.2M0.18%−5,767−7.6%Reduced
Arizona State Retirement System69,877$20.2M0.19%+356+0.5%Added
Stifel Financial Corp69,763$20.1M0.03%+5,939+9.3%Added
Moody Lynn & Lieberson, LLC68,809$19.9M1.82%+19,423+39.3%Added
Cercano Management LLC68,450$19.8M0.80%+68,450New
Summit Global Investments68,389$19.7M1.67%−4,619−6.3%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund66,888$19.3M0.27%−34,898−34.3%Reduced
Commonwealth Equity Services, LLC66,295$19.1M0.05%+2,992+4.7%Added
Creative Planning65,460$18.9M0.03%+56,673+645.0%Added
Capital International Ltd65,455$18.9M1.30%−5,395−7.6%Reduced
Cullinan Associates Inc64,881$18.7M1.04%−19,400−23.0%Reduced
CIBC Asset Management Inc64,461$18.6M0.08%−1,577−2.4%Reduced
HighTower Advisors, LLC63,828$18.4M0.04%+13,869+27.8%Added
Rafferty Asset Management, LLC63,552$18.4M0.15%+2,041+3.3%Added
State of Alaska, Department of Revenue63,310$18.3M0.23%+6,940+12.3%Added
Prudential PLC62,151$17.9M0.23%+3,879+6.7%Added
Tredje AP-fonden62,067$17.9M0.31%+4,418+7.7%Added
Vontobel Holding Ltd.62,699$17.9M0.18%+3,573+6.0%Added
Forsta Ap-Fonden61,400$17.7M0.20%+6,600+12.0%Added
Voloridge Investment Management, LLC60,891$17.6M0.10%+60,891New
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.60,527$17.5M7.60%+1,436+2.4%Added
Baird Financial Group, Inc.60,207$17.4M0.05%+4,055+7.2%Added
Varma Mutual Pension Insurance Co60,000$17.3M0.24%+15,492+34.8%Added
Foster Dykema Cabot & Co Inc58,352$16.9M2.36%+14,461+32.9%Added
Scout Investments, Inc.57,995$16.7M0.34%−56,701−49.4%Reduced
Advisor Group Holdings, Inc.57,772$16.7M0.03%−4,952−7.9%Reduced
Freemont Management S.A.57,700$16.7M2.66%+17,200+42.5%Added
Xponance, Inc.56,140$16.2M0.26%+4,870+9.5%Added
Walleye Capital LLC55,837$16.1M0.35%−11,186−16.7%Reduced
De Burlo Group Inc55,740$16.1M3.60%−6,680−10.7%Reduced
Edgemoor Investment Advisors, Inc.55,520$16.0M2.01%−310−0.6%Reduced
Churchill Management Corp55,174$15.9M0.39%+47,196+591.6%Added
Davidson Investment Advisors54,903$15.9M1.23%+418+0.8%Added
Vident Investment Advisory, LLC53,252$15.4M0.58%+21,209+66.2%Added
W.G. Shaheen & Associates DBA Whitney & Co52,862$15.3M2.80%+643+1.2%Added
Dai-Ichi Life Insurance Company, Ltd52,594$15.2M0.35%00.0%Unchanged
New York Life Investment Management LLC52,506$15.2M0.17%−242−0.5%Reduced
Trexquant Investment LP52,220$15.1M0.43%+23,040+79.0%Added
Capital International Sarl50,770$14.7M1.03%+3,057+6.4%Added
Industrial Alliance Investment Management Inc.50,189$14.5M0.40%−12,559−20.0%Reduced
BI Asset Management Fondsmaeglerselskab A/S50,047$14.5M0.38%+3,705+8.0%Added
Westpac Banking Corp50,028$14.4M0.21%+13,809+38.1%Added
USS Investment Management Ltd48,314$13.9M0.20%00.0%Unchanged
Nicholas Investment Partners, LP48,241$13.9M1.22%−14,538−23.2%Reduced
Achmea Investment Management B.V.51,394$13.9M0.47%+1,154+2.3%Added
South Dakota Investment Council47,601$13.7M0.31%−11,813−19.9%Reduced
Rockefeller Capital Management L.P.47,544$13.7M0.07%−241−0.5%Reduced
Clough Capital Partners L P47,211$13.6M1.38%+32,530+221.6%Added
IFM Investors Pty Ltd45,715$13.2M0.22%+1,184+2.7%Added
Utah Retirement Systems45,379$13.1M0.21%−469−1.0%Reduced
Group One Trading, L.P.45,103$13.0M0.44%+20,221+81.3%Added
Jag Capital Management, LLC44,051$12.7M1.85%−2,037−4.4%Reduced
Andra AP-fonden44,000$12.7M0.39%−13,000−22.8%Reduced
Citizens Financial Group Inc43,930$12.7M0.50%−1,770−3.9%Reduced
Azimuth Capital Investment Management LLC43,783$12.6M0.64%+8,353+23.6%Added
Swiss Life Asset Management Ltd43,667$12.6M0.21%+4,866+12.5%Added
Squarepoint Ops LLC43,497$12.6M0.09%+43,497New
Umb Bank N A43,408$12.5M0.20%+1,042+2.5%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys43,390$12.5M0.11%+5,878+15.7%Added
Shelter Mutual Insurance Co43,300$12.5M3.59%00.0%Unchanged
Factory Mutual Insurance Co43,200$12.5M0.19%00.0%Unchanged
Bank of Nova Scotia42,668$12.3M0.03%+8,942+26.5%Added
Gulf International Bank (UK) Ltd42,577$12.3M0.22%00.0%Unchanged
PFS Investments Inc.42,504$12.3M0.23%−1,560−3.5%Reduced
EULAV Asset Management42,000$12.1M0.52%−6,010−12.5%Reduced
Comerica Bank38,736$12.1M0.09%+3,190+9.0%Added
Profund Advisors LLC41,266$11.9M0.77%−180.0%Reduced
Longbow Finance SA41,063$11.9M1.60%+41,063New
First Republic Investment Management, Inc.40,318$11.6M0.03%−3,842−8.7%Reduced
Marvin & Palmer Associates Inc39,155$11.3M5.96%00.0%Unchanged
Balyasny Asset Management LLC37,821$10.9M0.04%+37,821New
Capital International Inc37,431$10.8M0.23%−5,379−12.6%Reduced
Banco Santander, S.A.37,335$10.8M0.16%−4,135−10.0%Reduced
Mutual of America Capital Management LLC36,631$10.6M0.13%+1,158+3.3%Added
Texas Permanent School Fund36,471$10.5M0.16%+184+0.5%Added
Seizert Capital Partners, LLC36,381$10.5M0.56%−3,438−8.6%Reduced
Yousif Capital Management, LLC35,863$10.4M0.14%+3,777+11.8%Added
McRae Capital Management Inc35,759$10.3M3.02%−606−1.7%Reduced
Verition Fund Management LLC35,686$10.3M0.20%−21,728−37.8%Reduced
Privium Fund Management B.V.35,307$10.2M3.87%+6,807+23.9%Added
Wealthfront Advisers LLC34,996$10.1M0.05%−3,525−9.2%Reduced
Washington Trust Bank34,219$9.88M1.12%+34,219New
2Xideas AG33,960$9.81M1.04%+1,776+5.5%Added
Point72 Middle East FZE33,235$9.60M0.74%+33,235New
CIBC World Markets Corp33,230$9.60M0.06%+29,339+754.0%Added
LVM Capital Management Ltd33,120$9.56M1.39%−1,240−3.6%Reduced
Cantor Fitzgerald, L. P.33,119$9.56M0.21%+33,119New
Hudson Bay Capital Management LP32,000$9.24M0.11%+32,000New
Public Sector Pension Investment Board31,958$9.23M0.07%+4,468+16.3%Added
Lindbrook Capital, LLC31,939$9.22M1.14%+24,198+312.6%Added
Mariner, LLC31,765$9.20M0.03%+13,022+69.5%Added
Nissay Asset Management Corp31,610$9.13M0.09%−1,204−3.7%Reduced
ExodusPoint Capital Management, LP30,468$8.80M0.14%+30,468New
Engineers Gate Manager LP30,297$8.75M0.53%+27,959+1,195.9%Added
J. Goldman & Co LP30,168$8.71M0.61%+30,168New