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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,072
+48 vs. Q4 2021
Shares held
235.3M
+5.08M (+2.2%) vs. Q4 2021
Total value
$60.9B
+$10.5B (+20.9%) vs. Q4 2021
New holders
150
417 more added
Sold out
102
373 more reduced

10 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 1,072 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2022: $60.9B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2021.

Institutions holding VRTX in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Candriam Luxembourg S.C.A.474,253$123.8M0.84%−170,379−26.4%Reduced
Artisan Partners Limited Partnership474,393$123.8M0.16%+12,079+2.6%Added
DekaBank Deutsche Girozentrale480,140$124.1M0.30%+141,885+41.9%Added
New York State Common Retirement Fund486,410$126.9M0.14%−3,438−0.7%Reduced
ProShare Advisors LLC488,976$127.6M0.27%−28,213−5.5%Reduced
AQR Capital Management LLC499,944$128.9M0.24%−98,539−16.5%Reduced
Holocene Advisors, LP499,771$130.4M0.69%+499,771New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.505,584$131.9M0.46%+259,205+105.2%Added
Citigroup Inc518,036$135.2M0.14%−141,335−21.4%Reduced
Victory Capital Management Inc521,538$138.3M0.14%+351,044+205.9%Added
Avidity Partners Management LP545,600$142.4M3.16%+265,600+94.9%Added
Parnassus Investments571,485$149.1M0.30%−47,953−7.7%Reduced
Barclays PLC572,035$149.3M0.12%−8,563−1.5%Reduced
Amundi592,498$163.4M0.11%−231,256−28.1%Reduced
Manufacturers Life Insurance Company, The638,594$165.9M0.11%+161,674+33.9%Added
Lord, Abbett & Co. LLC643,407$167.9M0.45%+643,407New
Credit Suisse AG661,475$172.6M0.15%+31,980+5.1%Added
Natixis Advisors, L.P.670,518$175.0M0.67%+2,716+0.4%Added
Allianz Asset Management GmbH672,655$175.5M0.14%+11,828+1.8%Added
Swedbank AB688,688$179.7M0.33%+24,532+3.7%Added
Manning & Napier Group, LLC694,759$181.3M1.73%−179,213−20.5%Reduced
D. E. Shaw & Co., Inc.744,248$194.2M0.26%−277,075−27.1%Reduced
Prudential Financial Inc748,855$195.4M0.26%+88,350+13.4%Added
Adage Capital Partners GP, L.L.C.793,290$207.0M0.39%+572,400+259.1%Added
Assenagon Asset Management S.A.808,554$211.0M0.69%+486,323+150.9%Added
Morgan Stanley825,849$215.5M0.03%−143,958−14.8%Reduced
Royal Bank of Canada840,095$219.2M0.06%+136,396+19.4%Added
Wells Fargo & Company851,082$222.1M0.06%+5,278+0.6%Added
Impax Asset Management Group plc860,672$224.6M0.93%−172,183−16.7%Reduced
Vaughan Nelson Investment Management, L.P.868,617$226.7M2.57%−55,130−6.0%Reduced
Lazard Asset Management LLC897,842$234.3M0.27%−17,878−2.0%Reduced
Pictet Asset Management SA907,666$236.9M0.27%−304,653−25.1%Reduced
Epoch Investment Partners, Inc.912,697$238.2M1.17%+92,849+11.3%Added
Dimensional Fund Advisors LP953,174$248.7M0.08%+19,141+2.0%Added
Sumitomo Mitsui Trust Holdings, Inc.975,384$254.5M0.17%−64,362−6.2%Reduced
Parametric Portfolio Associates LLC978,372$255.3M0.13%+101,365+11.6%Added
APG Asset Management N.V.1,156,889$271.3M0.51%−49,700−4.1%Reduced
American Century Companies Inc1,100,875$287.3M0.20%+476,422+76.3%Added
Swiss National Bank1,101,175$287.4M0.16%+115,100+11.7%Added
Franklin Resources Inc1,124,756$293.5M0.12%+65,455+6.2%Added
Caisse de Depot Et Placement du Quebec1,174,608$306.5M0.72%−53,900−4.4%Reduced
Nuveen Asset Management, LLC1,257,734$314.8M0.10%−86,100−6.4%Reduced
Invesco Ltd.1,210,357$315.9M0.08%+88,199+7.9%Added
Goldman Sachs Group Inc1,243,707$324.6M0.08%+56,330+4.7%Added
Charles Schwab Investment Management Inc1,327,466$346.4M0.10%+65,778+5.2%Added
Bellevue Group AG1,480,253$386.3M4.49%−311,508−17.4%Reduced
Harding Loevner LP1,769,276$417.3M2.30%−112,595−6.0%Reduced
Canada Pension Plan Investment Board1,640,031$428.0M0.57%−68,323−4.0%Reduced
Renaissance Technologies LLC1,707,368$445.6M0.52%+80,500+4.9%Added
Janus Henderson Group PLC1,805,599$471.2M0.23%−185,141−9.3%Reduced
California Public Employees Retirement System1,902,551$496.5M0.39%−36,268−1.9%Reduced
Bank of New York Mellon Corp2,002,865$522.7M0.10%−59,941−2.9%Reduced
Legal & General Group Plc2,057,129$536.8M0.16%+158,485+8.3%Added
Deutsche Bank AG2,148,626$560.7M0.26%−410,687−16.0%Reduced
Norges Bank2,624,748$685.0M0.15%−55,151−2.1%Reduced
Northern Trust Corp2,889,953$754.2M0.13%−18,399−0.6%Reduced
Bank of America Corp3,118,547$813.8M0.09%+20,530+0.7%Added
UBS Asset Management Americas Inc3,139,337$819.3M0.35%−374,894−10.7%Reduced
Massachusetts Financial Services Co3,515,153$917.4M0.27%+320,475+10.0%Added
Geode Capital Management, LLC4,330,231$1.13B0.14%−25,989−0.6%Reduced
JPMorgan Chase & Co4,812,669$1.26B0.16%+348,338+7.8%Added
Ameriprise Financial Inc4,947,363$1.29B0.38%+524,167+11.9%Added
Clearbridge Investments, LLC5,152,752$1.34B1.01%−43,978−0.8%Reduced
Price T Rowe Associates Inc5,304,697$1.38B0.14%−116,594−2.2%Reduced
Loomis Sayles & Co L P6,389,023$1.67B2.23%−246,230−3.7%Reduced
Wellington Management Group LLP8,053,710$2.10B0.36%+1,535,255+23.6%Added
Alliancebernstein L.P.10,555,041$2.75B1.06%+111,270+1.1%Added
State Street Corp12,052,763$3.15B0.16%−304,152−2.5%Reduced
Capital World Investors12,666,130$3.31B0.57%+1,145,275+9.9%Added
FMR LLC13,181,713$3.44B0.27%+4,087,860+45.0%Added
Vanguard Group Inc20,473,471$5.34B0.13%+317,629+1.6%Added
BlackRock Inc.23,916,254$6.24B0.17%−28,677−0.1%Reduced
Camber Capital Management LP0$00.00%−450,000−100.0%Sold out
Varenne Capital Partners0$00.00%−155,070−100.0%Sold out
Marshall Wace, LLP0$00.00%−150,000−100.0%Sold out
Melqart Asset Management (UK) Ltd0$00.00%−150,000−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−139,353−100.0%Sold out
Magnetar Financial LLC0$00.00%−81,724−100.0%Sold out
Kingdon Capital Management, L.L.C.0$00.00%−77,300−100.0%Sold out
HRT Financial LP0$00.00%−63,603−100.0%Sold out
Squarepoint Ops LLC0$00.00%−49,545−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−47,600−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−44,933−100.0%Sold out
Brookfield Asset Management Inc.0$00.00%−42,697−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−32,500−100.0%Sold out
Philadelphia Trust Co0$00.00%−26,985−100.0%Sold out
Covea Finance0$00.00%−24,544−100.0%Sold out
Arrowstreet Capital, Limited Partnership0$00.00%−24,249−100.0%Sold out
Quantitative Investment Management, LLC0$00.00%−21,622−100.0%Sold out
Advisors Asset Management, Inc.0$00.00%−21,242−100.0%Sold out
PointState Capital LP0$00.00%−17,500−100.0%Sold out
Ausdal Financial Partners, Inc.0$00.00%−14,981−100.0%Sold out
Berry Street Capital Management LLP0$00.00%−12,500−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−9,132−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−7,996−100.0%Sold out
Twinbeech Capital LP0$00.00%−7,909−100.0%Sold out
Fluent Financial, LLC0$00.00%−7,890−100.0%Sold out
First Quadrant L P0$00.00%−7,024−100.0%Sold out
Astrantus Ltd0$00.00%−6,300−100.0%Sold out
FORA Capital, LLC0$00.00%−5,909−100.0%Sold out