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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Pathstone Family Office, LLC4,483$985.0K0.02%+1,861+71.0%Added
Cetera Advisor Networks LLC4,583$1.01M0.01%+381+9.1%Added
Endurance Wealth Management, Inc.4,588$1.01M0.11%00.0%Unchanged
Walleye Trading LLC4,635$1.02M0.02%−18,039−79.6%Reduced
FIL Ltd4,663$1.02M0.00%+3,952+555.8%Added
Agf Investments Inc.4,666$1.02M0.01%+870+22.9%Added
Eqis Capital Management, Inc.4,709$1.03M0.08%−108−2.2%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC4,750$1.04M0.09%00.0%Unchanged
Leelyn Smith, LLC4,750$1.04M0.28%+551+13.1%Added
Icon Wealth Partners, LLC4,799$1.05M0.11%−141−2.9%Reduced
Strategic Wealth Management Inc4,841$1.06M0.53%−40−0.8%Reduced
Jefferies Group LLC4,875$1.07M0.02%−20,191−80.6%Reduced
Ramiah Investment Group4,978$1.09M0.74%+1,452+41.2%Added
Silverarc Capital Management, LLC5,000$1.10M0.49%+5,000New
Davidson Capital Management Inc.5,006$1.10M0.60%−1,228−19.7%Reduced
Regentatlantic Capital LLC5,070$1.11M0.03%+1,096+27.6%Added
HighVista Strategies LLC5,135$1.13M0.90%+5,135New
Cinctive Capital Management LP5,155$1.13M0.05%+5,155New
OPSEU Pension Plan Trust Fund5,134$1.14M0.26%+20+0.4%Added
Cetera Advisors LLC5,216$1.15M0.02%−12,737−70.9%Reduced
Wetherby Asset Management Inc5,228$1.15M0.06%+1,148+28.1%Added
Verition Fund Management LLC5,252$1.15M0.01%−12,458−70.3%Reduced
J. Goldman & Co LP5,262$1.16M0.11%+5,262New
Waldron Private Wealth LLC5,351$1.18M0.06%−204−3.7%Reduced
Commerce Bank5,389$1.18M0.01%+464+9.4%Added
Ferris Capital, LLC5,518$1.21M0.26%−32−0.6%Reduced
BerganKDV Wealth Management, LLC5,589$1.23M0.13%−82−1.4%Reduced
Wolff Wiese Magana LLC5,608$1.23M0.79%−53−0.9%Reduced
Wedbush Securities Inc5,687$1.25M0.05%−2,428−29.9%Reduced
Hohimer Wealth Management, LLC5,724$1.26M0.27%−211−3.6%Reduced
WP Advisors, LLC5,739$1.26M0.52%−738−11.4%Reduced
Two Sigma Securities, LLC5,746$1.26M0.25%+4,455+345.1%Added
Stonegate Investment Group, LLC5,747$1.26M0.05%+5,747New
North Star Asset Management Inc5,775$1.27M0.06%00.0%Unchanged
Nwam LLC5,774$1.27M0.10%+3,339+137.1%Added
Cigna Investments Inc5,792$1.27M0.10%−2,242−27.9%Reduced
Park Avenue Securities LLC5,828$1.28M0.02%−1,023−14.9%Reduced
Raymond James Trust N.A.5,831$1.28M0.04%−362−5.8%Reduced
Ieq Capital, LLC5,844$1.28M0.03%+2,209+60.8%Added
Belpointe Asset Management LLC5,978$1.29M0.08%+281+4.9%Added
Ci Investments Inc.5,889$1.29M0.00%+230+4.1%Added
FORA Capital, LLC5,909$1.30M0.50%−17−0.3%Reduced
Pitcairn Co5,988$1.31M0.08%+4,487+298.9%Added
Cohen Klingenstein LLC6,000$1.32M0.05%00.0%Unchanged
Tobam6,013$1.32M0.06%+381+6.8%Added
AlphaStar Capital Management, LLC5,664$1.33M0.11%+5,664New
Capital Investment Advisory Services, LLC6,043$1.33M0.16%−420−6.5%Reduced
Roberts Glore & Co Inc6,041$1.33M0.35%+386+6.8%Added
Federation des caisses Desjardins du Quebec6,048$1.33M0.01%−537−8.2%Reduced
Advisor Partners LLC6,052$1.33M0.08%+1,213+25.1%Added
J.P. Marvel Investment Advisors, LLC6,140$1.35M0.26%+6,140New
Synovus Financial Corp6,147$1.35M0.01%+500+8.9%Added
Vestcor Inc6,157$1.35M0.05%−947−13.3%Reduced
GAM Holding AG6,161$1.35M0.06%−1,074−14.8%Reduced
Banque Cantonale Vaudoise6,181$1.36M0.05%−8,088−56.7%Reduced
Parsec Financial Management, Inc.6,217$1.36M0.06%−235−3.6%Reduced
Private Harbour Investment Management & Counsel, LLC6,219$1.37M1.09%−15−0.2%Reduced
Astrantus Ltd6,300$1.38M1.03%+6,300New
Proequities, Inc.6,322$1.39M0.08%+303+5.0%Added
Caption Management, LLC6,400$1.41M0.09%−3,400−34.7%Reduced
Twin Capital Management Inc6,404$1.41M0.14%+1,229+23.7%Added
Oak Associates, Ltd6,406$1.41M0.07%−500−7.2%Reduced
Veritable, L.P.6,425$1.41M0.02%−317−4.7%Reduced
Creative Planning6,508$1.43M0.00%−32,516−83.3%Reduced
Motley Fool Asset Management LLC6,590$1.45M0.09%+53+0.8%Added
Palouse Capital Management, Inc.6,618$1.45M0.62%−1,090−14.1%Reduced
Baldwin Investment Management, LLC6,699$1.47M0.39%+649+10.7%Added
Kentucky Retirement Systems Insurance Trust Fund6,729$1.48M0.14%−90−1.3%Reduced
McGuire Investment Group, LLC6,788$1.49M0.25%−218−3.1%Reduced
National Bank of Canada6,739$1.49M0.01%+6,739New
AGF Investments LLC6,815$1.50M0.13%+766+12.7%Added
MidWestOne Financial Group, Inc.6,827$1.50M0.31%+4,082+148.7%Added
PKO Investment Management Joint-Stock Co7,000$1.54M0.17%+7,000New
First Quadrant L P7,024$1.54M0.17%00.0%Unchanged
Moody National Bank Trust Division7,096$1.56M0.05%−22,379−75.9%Reduced
Chartwell Investment Partners, LLC7,104$1.56M0.05%+1,703+31.5%Added
Wealthfront Advisers LLC7,123$1.56M0.01%+1,425+25.0%Added
Appleton Partners Inc7,132$1.57M0.12%−1,500−17.4%Reduced
Mark Sheptoff Financial Planning, LLC7,143$1.57M0.75%+100+1.4%Added
Moloney Securities Asset Management, LLC7,144$1.57M0.27%+7,144New
Redpoint Investment Management Pty Ltd7,187$1.58M0.13%00.0%Unchanged
Everence Capital Management Inc7,274$1.60M0.12%00.0%Unchanged
DuPont Capital Management Corp7,278$1.60M0.06%+831+12.9%Added
Sofos Investments, Inc.2,860$1.62M0.13%+2,853+40,757.1%Added
Zeke Capital Advisors, LLC7,440$1.63M0.10%+279+3.9%Added
EagleClaw Capital Managment, LLC7,440$1.63M0.36%+7,440New
Churchill Management Corp7,548$1.66M0.02%+7,548New
Northwestern Mutual Wealth Management Co7,556$1.66M0.00%+1,995+35.9%Added
Meiji Yasuda Life Insurance Co7,575$1.66M0.03%+153+2.1%Added
VELA Investment Management, LLC7,580$1.67M1.12%+7,580New
Griffin Asset Management, Inc.7,679$1.69M0.21%+805+11.7%Added
Crossmark Global Holdings, Inc.7,741$1.70M0.04%−210−2.6%Reduced
Oppenheimer & Co Inc7,765$1.71M0.03%+4,340+126.7%Added
Sectoral Asset Management Inc7,771$1.71M0.26%−1,950−20.1%Reduced
Baker Tilly Wealth Management, LLC7,772$1.71M0.18%+1,081+16.2%Added
Hellman Jordan Management Co Inc7,787$1.71M2.05%−3,074−28.3%Reduced
Fluent Financial, LLC7,890$1.73M0.71%−165−2.0%Reduced
Twinbeech Capital LP7,909$1.74M0.10%−59,347−88.2%Reduced
Strategic Global Advisors, LLC7,947$1.75M0.23%+622+8.5%Added
Cim Investment Mangement Inc7,944$1.75M0.52%+1,485+23.0%Added