Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Structure Therapeutics Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 198
- +1 vs. Q4 2025
- Shares held
- 66.8M
- +1.94M (+3.0%) vs. Q4 2025
- Total value
- $3.23B
- −$1.29B (−28.6%) vs. Q4 2025
- New holders
- 41
- 72 more added
- Sold out
- 40
- 58 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Flax Pond Capital, LLC | 36,000 | $1.74M | 1.40% | −12,721−26.1% | Reduced |
| Headlands Technologies LLC | 37,156 | $1.79M | 0.20% | −6,573−15.0% | Reduced |
| Bank of Montreal | 39,984 | $1.93M | 0.00% | −14,357−26.4% | Reduced |
| Voya Investment Management LLC | 44,410 | $2.14M | 0.00% | −10,890−19.7% | Reduced |
| Advisor Group Holdings, Inc. | 44,416 | $2.14M | 0.00% | −14,822−25.0% | Reduced |
| Raymond James Financial Inc | 45,139 | $2.18M | 0.00% | +751+1.7% | Added |
| Antipodes Partners Ltd | 45,361 | $2.19M | 0.04% | −930−2.0% | Reduced |
| Brevan Howard Capital Management LP | 47,266 | $2.20M | 0.02% | −39,044−45.2% | Reduced |
| DAFNA Capital Management LLC | 46,500 | $2.24M | 0.51% | +9,500+25.7% | Added |
| Pier Capital, LLC | 47,551 | $2.29M | 0.38% | −1,206−2.5% | Reduced |
| State Street Corp | 47,581 | $2.29M | 0.00% | −643−1.3% | Reduced |
| Banque Pictet & Cie SA | 49,367 | $2.38M | 0.03% | −10,514−17.6% | Reduced |
| Monashee Investment Management LLC | 50,000 | $2.41M | 1.31% | −175,000−77.8% | Reduced |
| Seven Grand Managers, LLC | 50,000 | $2.41M | 0.16% | 00.0% | Unchanged |
| Buckland Partners Management Co LLC | 50,000 | $2.41M | 1.46% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 50,800 | $2.45M | 0.42% | +9,800+23.9% | Added |
| Renaissance Technologies LLC | 55,800 | $2.69M | 0.00% | −59,400−51.6% | Reduced |
| Susquehanna International Group, LLP | 55,842 | $2.69M | 0.00% | +46,843+520.5% | Added |
| Alps Advisors Inc | 57,667 | $2.78M | 0.01% | +7,941+16.0% | Added |
| Burkehill Global Management, LP | 60,000 | $2.89M | 0.14% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 60,517 | $2.92M | 0.04% | −7,572−11.1% | Reduced |
| Jefferies Financial Group Inc. | 62,592 | $3.02M | 0.04% | −40,401−39.2% | Reduced |
| Platinum Investment Management Ltd | 66,864 | $3.22M | 0.81% | −21,010−23.9% | Reduced |
| Geode Capital Management, LLC | 67,862 | $3.27M | 0.00% | +12,714+23.1% | Added |
| Marshall Wace, LLP | 69,107 | $3.33M | 0.00% | −99,477−59.0% | Reduced |
| Diadema Partners LP | 72,234 | $3.48M | 1.44% | +72,234 | New |
| Qube Research & Technologies Ltd | 73,599 | $3.55M | 0.01% | +73,599 | New |
| Boxer Capital Management, LLC | 75,000 | $3.62M | 0.47% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 75,301 | $3.63M | 0.02% | +40,248+114.8% | Added |
| Soleus Capital Management, L.P. | 80,000 | $3.86M | 0.16% | −10,000−11.1% | Reduced |
| Peregrine Capital Management LLC | 97,117 | $4.68M | 0.17% | +12,793+15.2% | Added |
| Birchview Capital, LP | 100,000 | $4.82M | 2.74% | +10,000+11.1% | Added |
| Jones Hill Capital LP | 100,593 | $4.85M | 1.04% | +100,593 | New |
| Schroder Investment Management Group | 118,225 | $5.19M | 0.00% | +118,225 | New |
| Jump Financial, LLC | 107,857 | $5.20M | 0.08% | +107,857 | New |
| Trexquant Investment LP | 107,884 | $5.20M | 0.04% | +17,939+19.9% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 109,638 | $5.28M | 0.01% | +26,586+32.0% | Added |
| Manufacturers Life Insurance Company, The | 114,814 | $5.53M | 0.00% | +18,427+19.1% | Added |
| HighVista Strategies LLC | 123,909 | $5.97M | 1.65% | −69,092−35.8% | Reduced |
| PFM Health Sciences, LP | 126,383 | $6.09M | 0.64% | +58,135+85.2% | Added |
| Davern Capital Partners, LP | 126,461 | $6.10M | 1.67% | +126,461 | New |
| B Group, Inc. | 127,500 | $6.15M | 4.56% | +37,500+41.7% | Added |
| Rhenman & Partners Asset Management AB | 128,100 | $6.17M | 0.76% | −19,500−13.2% | Reduced |
| SC China Holding Ltd | 266,062 | $6.20M | 0.41% | 00.0% | Unchanged |
| NEXTBio Capital Management LP | 133,239 | $6.42M | 2.98% | +38,796+41.1% | Added |
| Nomura Asset Management International Inc. | 134,015 | $6.46M | 0.01% | +51,370+62.2% | Added |
| Eversept Partners, LP | 138,036 | $6.65M | 0.44% | +10,475+8.2% | Added |
| TCG Crossover Management, LLC | 140,411 | $6.77M | 0.19% | −780,446−84.8% | Reduced |
| Holocene Advisors, LP | 159,009 | $7.66M | 0.02% | +159,009 | New |
| Schonfeld Strategic Advisors LLC | 165,426 | $7.97M | 0.06% | +156,699+1,795.6% | Added |
| Millennium Management LLC | 168,931 | $8.14M | 0.01% | +16,371+10.7% | Added |
| Cormorant Asset Management, LP | 175,000 | $8.44M | 0.43% | +175,000 | New |
| Two Sigma Investments, LP | 181,415 | $8.74M | 0.01% | +85,872+89.9% | Added |
| ArrowMark Colorado Holdings LLC | 188,195 | $9.07M | 0.24% | −83,018−30.6% | Reduced |
| Woodline Partners LP | 190,808 | $9.20M | 0.03% | +66,906+54.0% | Added |
| JPMorgan Chase & Co | 212,803 | $9.35M | 0.00% | +199,847+1,542.5% | Added |
| StemPoint Capital LP | 200,267 | $9.65M | 1.86% | −150,806−43.0% | Reduced |
| TD Asset Management Inc | 204,762 | $9.87M | 0.01% | +30,088+17.2% | Added |
| D. E. Shaw & Co., Inc. | 204,790 | $9.87M | 0.01% | +196,167+2,274.9% | Added |
| Sio Capital Management, LLC | 209,093 | $10.1M | 1.45% | +7,593+3.8% | Added |
| UBS Group AG | 212,919 | $10.3M | 0.00% | +10,442+5.2% | Added |
| Ameriprise Financial Inc | 219,516 | $10.6M | 0.00% | −66,002−23.1% | Reduced |
| Bank of America Corp | 227,132 | $10.9M | 0.00% | +195,454+617.0% | Added |
| Parkman Healthcare Partners LLC | 232,093 | $11.2M | 1.16% | +177,093+322.0% | Added |
| Pentwater Capital Management LP | 245,000 | $11.8M | 0.08% | +245,000 | New |
| SEB Asset Management AB | 245,043 | $11.8M | 0.05% | +245,043 | New |
| Voloridge Investment Management, LLC | 254,969 | $12.3M | 0.05% | +4,969+2.0% | Added |
| Catalio Capital Management, LP | 255,379 | $12.3M | 2.57% | +2,478+1.0% | Added |
| Goldman Sachs Group Inc | 260,543 | $12.6M | 0.00% | +36,211+16.1% | Added |
| Balyasny Asset Management LLC | 304,934 | $14.7M | 0.03% | +88,735+41.0% | Added |
| National Bank of Canada | 305,400 | $14.7M | 0.02% | +40,000+15.1% | Added |
| Deutsche Bank AG | 331,867 | $16.0M | 0.01% | −509,295−60.5% | Reduced |
| Standard Life Aberdeen plc | 391,809 | $18.9M | 0.03% | +126,940+47.9% | Added |
| BlackRock, Inc. | 441,975 | $21.3M | 0.00% | +11,893+2.8% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 467,800 | $22.5M | 0.04% | 00.0% | Unchanged |
| Logos Global Management LP | 500,000 | $24.1M | 1.24% | −100,000−16.7% | Reduced |
| Franklin Resources Inc | 531,595 | $25.6M | 0.01% | −338,987−38.9% | Reduced |
| Paradigm Biocapital Advisors LP | 545,287 | $26.3M | 0.54% | +545,287 | New |
| Rock Springs Capital Management LP | 640,217 | $30.9M | 1.82% | −108,019−14.4% | Reduced |
| Pacific Heights Asset Management LLC | 750,000 | $36.1M | 1.21% | +50,000+7.1% | Added |
| Deerfield Management Company, L.P. (Series C) | 767,993 | $37.0M | 0.44% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 638,813 | $44.4M | 0.01% | −210,038−24.7% | Reduced |
| Capitolis Liquid Global Markets LLC | 1,151,300 | $55.5M | 0.35% | +1,151,300 | New |
| Casdin Capital, LLC | 1,175,000 | $56.6M | 4.29% | 00.0% | Unchanged |
| Siren, L.L.C. | 1,328,698 | $64.0M | 1.78% | +250,000+23.2% | Added |
| Baker Bros. Advisors LP | 1,432,529 | $69.0M | 0.40% | 00.0% | Unchanged |
| American Century Companies Inc | 1,438,031 | $69.3M | 0.04% | +931,072+183.7% | Added |
| OrbiMed Advisors LLC | 1,475,403 | $71.1M | 1.62% | +313,600+27.0% | Added |
| Driehaus Capital Management LLC | 1,577,356 | $76.0M | 0.56% | −65,088−4.0% | Reduced |
| Principal Financial Group Inc | 1,753,764 | $84.5M | 0.05% | +469,554+36.6% | Added |
| Price T Rowe Associates Inc | 2,000,696 | $96.4M | 0.01% | +329,558+19.7% | Added |
| Morgan Stanley | 2,305,457 | $111.1M | 0.01% | +217,623+10.4% | Added |
| BVF Inc | 3,459,358 | $166.7M | 5.31% | −19,664−0.6% | Reduced |
| Deep Track Capital, LP | 4,279,848 | $206.3M | 4.26% | +168,066+4.1% | Added |
| Janus Henderson Group PLC | 5,354,981 | $258.3M | 0.12% | +264,833+5.2% | Added |
| Avoro Capital Advisors LLC | 6,555,555 | $316.0M | 3.11% | 00.0% | Unchanged |
| Wellington Management Group LLP | 7,260,287 | $349.9M | 0.07% | +138,303+1.9% | Added |
| FMR LLC | 8,403,449 | $405.0M | 0.02% | −308,802−3.5% | Reduced |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −772,518−100.0% | Sold out |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −454,000−100.0% | Sold out |