Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 165
- +6 vs. Q3 2024
- Shares held
- 60.9M
- −620.5K (−1.0%) vs. Q3 2024
- Total value
- $1.65B
- −$1.04B (−38.7%) vs. Q3 2024
- New holders
- 29
- 66 more added
- Sold out
- 23
- 49 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wellington Management Group LLP | 7,785,614 | $211.1M | 0.04% | +15,843+0.2% | Added |
| FMR LLC | 6,078,746 | $164.9M | 0.01% | −49,698−0.8% | Reduced |
| Janus Henderson Group PLC | 4,159,888 | $112.8M | 0.06% | +203,010+5.1% | Added |
| Capital Research Global Investors | 3,537,341 | $95.9M | 0.02% | +6,891+0.2% | Added |
| Deep Track Capital, LP | 2,800,000 | $75.9M | 2.85% | +1,579,492+129.4% | Added |
| Driehaus Capital Management LLC | 2,057,410 | $55.8M | 0.46% | −469,020−18.6% | Reduced |
| Federated Hermes, Inc. | 2,045,958 | $55.5M | 0.12% | −365,642−15.2% | Reduced |
| BVF Inc | 1,771,417 | $48.0M | 1.63% | −467,569−20.9% | Reduced |
| Vestal Point Capital, LP | 1,725,000 | $46.8M | 2.77% | +575,000+50.0% | Added |
| Capital International Investors | 1,619,081 | $43.9M | 0.01% | +103,059+6.8% | Added |
| Ra Capital Management, L.P. | 1,517,418 | $41.2M | 0.55% | −379,354−20.0% | Reduced |
| Citadel Advisors LLC | 1,479,339 | $40.1M | 0.04% | +27,841+1.9% | Added |
| Ameriprise Financial Inc | 1,420,052 | $38.5M | 0.01% | +322,601+29.4% | Added |
| Price T Rowe Associates Inc | 1,394,306 | $37.8M | 0.00% | −690,381−33.1% | Reduced |
| FIL Ltd | 1,300,015 | $35.3M | 0.03% | −10,520−0.8% | Reduced |
| Rock Springs Capital Management LP | 1,080,963 | $29.3M | 1.12% | +17,053+1.6% | Added |
| TCG Crossover Management, LLC | 1,063,000 | $28.8M | 2.82% | 00.0% | Unchanged |
| Principal Financial Group Inc | 791,134 | $21.5M | 0.01% | +245,775+45.1% | Added |
| Millennium Management LLC | 751,013 | $20.4M | 0.02% | −160,438−17.6% | Reduced |
| Franklin Resources Inc | 738,090 | $20.0M | 0.01% | +31,984+4.5% | Added |
| Logos Global Management LP | 700,000 | $19.0M | 2.22% | −550,000−44.0% | Reduced |
| Casdin Capital, LLC | 700,000 | $19.0M | 1.27% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 652,028 | $17.7M | 0.37% | +268,323+69.9% | Added |
| American Century Companies Inc | 612,616 | $16.6M | 0.01% | +67,325+12.3% | Added |
| BlackRock, Inc. | 610,585 | $16.6M | 0.00% | −69,512−10.2% | Reduced |
| Marshall Wace, LLP | 583,207 | $15.8M | 0.02% | +450,531+339.6% | Added |
| Goldman Sachs Group Inc | 582,865 | $15.8M | 0.00% | −129,930−18.2% | Reduced |
| Catalio Capital Management, LP | 569,395 | $15.4M | 3.38% | +569,395 | New |
| Boxer Capital Management, LLC | 500,000 | $13.6M | 1.15% | +500,000 | New |
| Bellevue Group AG | 485,050 | $13.2M | 0.25% | −144,708−23.0% | Reduced |
| Point72 Asset Management, L.P. | 476,698 | $12.9M | 0.04% | −761,570−61.5% | Reduced |
| Foresite Capital Management VI LLC | 420,000 | $11.4M | 5.08% | +420,000 | New |
| First Light Asset Management, LLC | 398,855 | $10.8M | 1.03% | −107,367−21.2% | Reduced |
| Morgan Stanley | 387,176 | $10.5M | 0.00% | +224,690+138.3% | Added |
| Deerfield Management Company, L.P. (Series C) | 373,407 | $10.1M | 0.19% | −471,000−55.8% | Reduced |
| Invesco Ltd. | 371,767 | $10.1M | 0.00% | +14,559+4.1% | Added |
| Baker Bros. Advisors LP | 361,565 | $9.81M | 0.10% | +276,065+322.9% | Added |
| Woodline Partners LP | 333,901 | $9.06M | 0.06% | +2,328+0.7% | Added |
| Ensign Peak Advisors, Inc | 308,241 | $8.36M | 0.01% | +124,456+67.7% | Added |
| Camber Capital Management LP | 300,000 | $8.14M | 0.32% | +300,000 | New |
| Ikarian Capital, LLC | 284,085 | $7.70M | 2.20% | +168,885+146.6% | Added |
| SC China Holding Ltd | 266,062 | $7.54M | 0.32% | 00.0% | Unchanged |
| Schroder Investment Management Group | 275,311 | $7.33M | 0.01% | +147,475+115.4% | Added |
| UBS Group AG | 244,063 | $6.62M | 0.00% | +204,983+524.5% | Added |
| ArrowMark Colorado Holdings LLC | 232,909 | $6.32M | 0.08% | −8,183−3.4% | Reduced |
| Nantahala Capital Management, LLC | 221,000 | $5.99M | 0.42% | +50,000+29.2% | Added |
| Superstring Capital Management LP | 216,811 | $5.88M | 5.16% | −10,236−4.5% | Reduced |
| Candriam Luxembourg S.C.A. | 215,421 | $5.84M | 0.03% | +80,421+59.6% | Added |
| Readystate Asset Management LP | 209,342 | $5.68M | 0.24% | +125,342+149.2% | Added |
| Standard Life Aberdeen plc | 171,388 | $4.65M | 0.01% | −45,695−21.0% | Reduced |
| Handelsbanken Fonder AB | 165,000 | $4.47M | 0.02% | +165,000 | New |
| Silverarc Capital Management, LLC | 152,395 | $4.13M | 0.92% | +81,879+116.1% | Added |
| Exome Asset Management LLC | 151,965 | $4.12M | 3.10% | +31,800+26.5% | Added |
| CCG Wealth Management, LLC | 150,000 | $4.07M | 2.27% | +150,000 | New |
| Alliancebernstein L.P. | 142,825 | $3.87M | 0.00% | −16,372−10.3% | Reduced |
| Pier Capital, LLC | 132,604 | $3.60M | 0.51% | −1,687−1.3% | Reduced |
| Monashee Investment Management LLC | 132,000 | $3.58M | 0.49% | −27,608−17.3% | Reduced |
| Royal Bank of Canada | 125,692 | $3.41M | 0.00% | +8,147+6.9% | Added |
| RTW Investments, LP | 125,000 | $3.39M | 0.05% | 00.0% | Unchanged |
| Jane Street Group, LLC | 116,013 | $3.15M | 0.01% | +77,176+198.7% | Added |
| Barclays PLC | 115,671 | $3.14M | 0.00% | +34,533+42.6% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 113,992 | $3.09M | 0.01% | +113,992 | New |
| TD Asset Management Inc | 88,882 | $2.41M | 0.00% | −101,874−53.4% | Reduced |
| Boothbay Fund Management, LLC | 83,148 | $2.25M | 0.07% | +49,485+147.0% | Added |
| Wexford Capital LP | 81,872 | $2.22M | 0.57% | −16,351−16.6% | Reduced |
| Platinum Investment Management Ltd | 74,900 | $2.03M | 0.12% | +17,670+30.9% | Added |
| Banque Pictet & Cie SA | 74,177 | $2.01M | 0.02% | −6,876−8.5% | Reduced |
| Citigroup Inc | 74,084 | $2.01M | 0.00% | +72,533+4,676.5% | Added |
| Susquehanna International Group, LLP | 68,203 | $1.85M | 0.00% | +4,422+6.9% | Added |
| Capital Fund Management S.A. | 67,135 | $1.82M | 0.02% | +17,007+33.9% | Added |
| Fred Alger Management, LLC | 66,662 | $1.81M | 0.01% | −51−0.1% | Reduced |
| Manufacturers Life Insurance Company, The | 58,242 | $1.58M | 0.00% | −28,600−32.9% | Reduced |
| Macquarie Group Ltd | 58,000 | $1.57M | 0.00% | 00.0% | Unchanged |
| Zimmer Partners, LP | 56,900 | $1.54M | 0.03% | −154,200−73.0% | Reduced |
| Bank of America Corp | 54,185 | $1.47M | 0.00% | −43,206−44.4% | Reduced |
| Trexquant Investment LP | 52,876 | $1.43M | 0.02% | +45,235+592.0% | Added |
| Bank of Montreal | 50,173 | $1.36M | 0.00% | +3,671+7.9% | Added |
| Sectoral Asset Management Inc | 49,250 | $1.34M | 0.89% | +24,855+101.9% | Added |
| Alps Advisors Inc | 46,300 | $1.26M | 0.01% | +46,300 | New |
| Geode Capital Management, LLC | 45,705 | $1.24M | 0.00% | +480+1.1% | Added |
| NEOS Investment Management LLC | 44,343 | $1.20M | 0.03% | +29,542+199.6% | Added |
| Tema ETFs LLC | 44,343 | $1.20M | 0.50% | +44,343 | New |
| TrueMark Investments, LLC | 42,127 | $1.14M | 0.36% | −3,353−7.4% | Reduced |
| Exchange Traded Concepts, LLC | 40,435 | $1.10M | 0.02% | −666−1.6% | Reduced |
| Nomura Asset Management Co Ltd | 36,925 | $1.00M | 0.00% | +7,496+25.5% | Added |
| DAFNA Capital Management LLC | 35,500 | $962.8K | 0.24% | +1,500+4.4% | Added |
| ADAR1 Capital Management, LLC | 35,319 | $957.9K | 0.20% | +35,319 | New |
| Russell Investments Group, Ltd. | 34,671 | $940.3K | 0.00% | +2,888+9.1% | Added |
| JPMorgan Chase & Co | 32,315 | $876.4K | 0.00% | −1,621−4.8% | Reduced |
| Prelude Capital Management, LLC | 32,000 | $867.8K | 0.07% | +7,023+28.1% | Added |
| Point72 Europe (London) LLP | 31,420 | $852.1K | 0.05% | −13,413−29.9% | Reduced |
| Advisor Group Holdings, Inc. | 30,792 | $835.0K | 0.00% | +30,272+5,821.5% | Added |
| Twinbeech Capital LP | 28,268 | $766.6K | 0.01% | +7,220+34.3% | Added |
| Voya Investment Management LLC | 25,940 | $703.5K | 0.00% | −20,830−44.5% | Reduced |
| Mariner, LLC | 24,530 | $665.3K | 0.00% | +24,530 | New |
| Group One Trading, L.P. | 21,567 | $584.9K | 0.02% | +15,758+271.3% | Added |
| Money Concepts Capital Corp | 21,031 | $570.4K | 0.04% | +848+4.2% | Added |
| Sofinnova Investments, Inc. | 20,892 | $566.6K | 0.04% | −17,900−46.1% | Reduced |
| UBS Oconnor LLC | 19,520 | $529.4K | 0.01% | +1,520+8.4% | Added |
| M&T Bank Corp | 18,110 | $491.6K | 0.00% | +9,055+100.0% | Added |