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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Structure Therapeutics Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
191
−5 vs. Q1 2026
Shares held
67.6M
+5.87M (+9.5%) vs. Q1 2026
Total value
$3.62B
+$643.8M (+21.6%) vs. Q1 2026
New holders
27
76 more added
Sold out
32
53 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 191 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 38 institutionsQ2 2023: 48 institutionsQ3 2023: 84 institutionsQ4 2023: 122 institutionsQ1 2024: 119 institutionsQ2 2024: 167 institutionsQ3 2024: 161 institutionsQ4 2024: 165 institutionsQ1 2025: 151 institutionsQ2 2025: 173 institutionsQ3 2025: 158 institutionsQ4 2025: 199 institutionsQ1 2026: 198 institutionsQ2 2026: 191 institutions
Value heldQ2 2026: $3.62B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $375.9MQ2 2023: $699.4MQ3 2023: $1.64BQ4 2023: $1.75BQ1 2024: $1.89BQ2 2024: $2.38BQ3 2024: $2.70BQ4 2024: $1.65BQ1 2025: $990.4MQ2 2025: $1.14BQ3 2025: $1.59BQ4 2025: $4.58BQ1 2026: $3.24BQ2 2026: $3.62B
Institutions holding GPCR and their total value by quarter
QuarterHoldersValue
Q2 2026191$3.62B
Q1 2026198$3.24B
Q4 2025199$4.58B
Q3 2025158$1.59B
Q2 2025173$1.14B
Q1 2025151$990.4M
Q4 2024165$1.65B
Q3 2024161$2.70B
Q2 2024167$2.38B
Q1 2024119$1.89B
Q4 2023122$1.75B
Q3 202384$1.64B
Q2 202348$699.4M
Q1 202338$375.9M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q1 2026.

Institutions holding GPCR in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC7,810,306$419.2M0.02%−593,143−7.1%Reduced
Wellington Management Group LLP7,379,433$396.1M0.07%+119,146+1.6%Added
Avoro Capital Advisors LLC6,555,555$351.8M3.16%00.0%Unchanged
Jupiter Topco LLC5,204,212$279.3M0.11%+5,204,212New
Deep Track Capital, LP4,740,072$254.4M3.75%+460,224+10.8%Added
BVF Inc3,366,823$180.7M4.62%−92,535−2.7%Reduced
Morgan Stanley2,806,640$150.6M0.01%+501,183+21.7%Added
OrbiMed Advisors LLC2,209,400$118.6M2.25%+733,997+49.7%Added
Principal Financial Group Inc1,752,753$94.1M0.05%−1,011−0.1%Reduced
American Century Companies Inc1,682,179$90.3M0.04%+244,148+17.0%Added
RTW Investments, LP1,607,507$86.3M0.74%+1,607,507New
Driehaus Capital Management LLC1,553,219$83.4M0.48%−24,137−1.5%Reduced
Baker Bros. Advisors LP1,432,529$76.9M0.39%00.0%Unchanged
Casdin Capital, LLC1,175,000$63.1M3.16%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)1,086,000$58.3M0.61%+318,007+41.4%Added
Capitolis Liquid Global Markets LLC1,041,100$55.9M0.24%−110,200−9.6%Reduced
Siren, L.L.C.872,967$46.9M0.95%−455,731−34.3%Reduced
Price T Rowe Associates Inc845,532$45.4M0.00%−1,155,164−57.7%Reduced
Pacific Heights Asset Management LLC800,000$42.9M1.36%+50,000+6.7%Added
Rock Springs Capital Management LP640,317$34.4M1.68%+1000.0%Added
Standard Life Aberdeen plc639,915$34.3M0.05%+248,106+63.3%Added
Franklin Resources Inc578,839$31.1M0.01%+47,244+8.9%Added
Bank of America Corp563,422$30.2M0.00%+336,290+148.1%Added
Alliancebernstein L.P.611,708$29.5M0.01%−27,105−4.2%Reduced
BlackRock, Inc.511,149$27.4M0.00%+69,174+15.7%Added
Logos Global Management LP500,000$26.8M1.16%00.0%Unchanged
Parkman Healthcare Partners LLC485,661$26.1M2.68%+253,568+109.3%Added
Davern Capital Partners, LP446,059$23.9M4.08%+319,598+252.7%Added
Healthcare of Ontario Pension Plan Trust Fund418,800$22.5M0.03%−49,000−10.5%Reduced
UBS Group AG378,986$20.3M0.00%+166,067+78.0%Added
Deutsche Bank AG331,867$17.8M0.01%00.0%Unchanged
NEXTBio Capital Management LP312,496$16.8M7.71%+179,257+134.5%Added
Catalio Capital Management, LP276,550$14.8M2.79%+21,171+8.3%Added
Marshall Wace, LLP267,592$14.4M0.01%+198,485+287.2%Added
SC China Holding Ltd266,062$14.3M1.19%00.0%Unchanged
SEB Asset Management AB245,043$13.2M0.05%00.0%Unchanged
Goldman Sachs Group Inc242,790$13.0M0.00%−17,753−6.8%Reduced
Ameriprise Financial Inc230,514$12.4M0.00%+10,998+5.0%Added
National Bank of Canada215,800$11.6M0.01%−89,600−29.3%Reduced
Two Sigma Investments, LP204,156$11.0M0.01%+22,741+12.5%Added
Eversept Partners, LP196,302$10.5M0.57%+58,266+42.2%Added
Schonfeld Strategic Advisors LLC190,685$10.2M0.05%+25,259+15.3%Added
Woodline Partners LP153,808$8.25M0.03%−37,000−19.4%Reduced
Nomura Asset Management International Inc.153,119$8.22M0.01%+19,104+14.3%Added
ArrowMark Colorado Holdings LLC150,579$8.08M0.34%−37,616−20.0%Reduced
Susquehanna Portfolio Strategies, LLC148,948$7.99M0.13%+88,431+146.1%Added
CenterBook Partners LP148,030$7.94M0.39%+126,793+597.0%Added
Rhenman & Partners Asset Management AB145,100$7.79M0.74%+17,000+13.3%Added
B Group, Inc.140,000$7.51M4.26%+12,500+9.8%Added
HighVista Strategies LLC130,784$7.02M1.60%+6,875+5.5%Added
Universal- Beteiligungs- und Servicegesellschaft mbH125,689$6.75M0.01%+16,051+14.6%Added
Squarepoint Ops LLC125,575$6.74M0.01%+102,929+454.5%Added
Susquehanna International Group, LLP122,344$6.57M0.01%+66,502+119.1%Added
D. E. Shaw & Co., Inc.115,300$6.19M0.00%−89,490−43.7%Reduced
Voloridge Investment Management, LLC112,300$6.03M0.03%−142,669−56.0%Reduced
Soleus Capital Management, L.P.107,000$5.74M0.20%+27,000+33.8%Added
Avidity Partners Management LP98,000$5.26M0.84%+20,000+25.6%Added
Geode Capital Management, LLC97,183$5.22M0.00%+29,321+43.2%Added
Qube Research & Technologies Ltd93,403$5.01M0.01%+19,804+26.9%Added
Peregrine Capital Management LLC92,229$4.95M0.16%−4,888−5.0%Reduced
PFM Health Sciences, LP91,550$4.91M0.43%−34,833−27.6%Reduced
Platinum Investment Management Ltd90,363$4.85M1.19%+23,499+35.1%Added
Millennium Management LLC89,568$4.81M0.00%−79,363−47.0%Reduced
ExodusPoint Capital Management, LP78,266$4.20M0.04%+78,266New
Cormorant Asset Management, LP75,000$4.03M0.21%−100,000−57.1%Reduced
Boxer Capital Management, LLC75,000$4.03M0.30%00.0%Unchanged
Adage Capital Partners GP, L.L.C.75,000$4.03M0.01%+75,000New
Alps Advisors Inc71,833$3.86M0.02%+14,166+24.6%Added
Flax Pond Capital, LLC73,000$3.72M1.38%+37,000+102.8%Added
TD Asset Management Inc68,962$3.70M0.00%−135,800−66.3%Reduced
Brevan Howard Capital Management LP60,336$3.26M0.05%+13,070+27.7%Added
Burkehill Global Management, LP60,000$3.22M0.12%00.0%Unchanged
Raymond James Financial Inc59,357$3.19M0.00%+14,218+31.5%Added
Tudor Investment Corp Et Al53,656$2.88M0.01%−21,645−28.7%Reduced
Antipodes Partners Ltd51,262$2.75M0.05%+5,901+13.0%Added
Seven Grand Managers, LLC50,000$2.68M0.11%00.0%Unchanged
Buckland Partners Management Co LLC50,000$2.68M1.31%00.0%Unchanged
DAFNA Capital Management LLC46,500$2.50M0.48%00.0%Unchanged
Mariner, LLC46,285$2.48M0.00%+11,805+34.2%Added
Advisor Group Holdings, Inc.44,786$2.40M0.00%+370+0.8%Added
State Street Corp44,629$2.40M0.00%−2,952−6.2%Reduced
Voya Investment Management LLC44,410$2.38M0.00%00.0%Unchanged
Banque Pictet & Cie SA43,332$2.33M0.02%−6,035−12.2%Reduced
Jump Financial, LLC42,658$2.29M0.02%−65,199−60.4%Reduced
Bank of Montreal42,570$2.28M0.00%+2,586+6.5%Added
Cinctive Capital Management LP40,877$2.19M0.09%+32,163+369.1%Added
Jefferies Financial Group Inc.40,625$2.18M0.02%−21,967−35.1%Reduced
Jones Hill Capital LP40,567$2.18M0.46%−60,026−59.7%Reduced
StemPoint Capital LP38,178$2.05M0.35%−362,356−90.5%Reduced
Manufacturers Life Insurance Company, The38,108$2.05M0.00%−76,706−66.8%Reduced
Capital Fund Management S.A.37,281$2.00M0.01%+4,845+14.9%Added
PSquared Asset Management AG37,200$2.00M0.65%+2,200+6.3%Added
TrueMark Investments, LLC33,600$1.80M0.23%−777−2.3%Reduced
Nomura Asset Management Co Ltd32,790$1.76M0.00%00.0%Unchanged
DCF Advisers, LLC32,100$1.72M0.45%+4,600+16.7%Added
Exchange Traded Concepts, LLC30,773$1.65M0.01%+5,395+21.3%Added
Private Capital Advisors, Inc.29,760$1.60M0.14%−4,629−13.5%Reduced
Gsa Capital Partners LLP28,665$1.54M0.10%+14,854+107.6%Added
Sphera Funds Management Ltd.28,600$1.53M0.22%−22,200−43.7%Reduced
Verition Fund Management LLC28,519$1.53M0.01%+445+1.6%Added