Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Structure Therapeutics Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 198
- +1 vs. Q4 2025
- Shares held
- 66.8M
- +1.94M (+3.0%) vs. Q4 2025
- Total value
- $3.23B
- −$1.29B (−28.6%) vs. Q4 2025
- New holders
- 41
- 72 more added
- Sold out
- 40
- 58 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 8,403,449 | $405.0M | 0.02% | −308,802−3.5% | Reduced |
| Wellington Management Group LLP | 7,260,287 | $349.9M | 0.07% | +138,303+1.9% | Added |
| Avoro Capital Advisors LLC | 6,555,555 | $316.0M | 3.11% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 5,354,981 | $258.3M | 0.12% | +264,833+5.2% | Added |
| Deep Track Capital, LP | 4,279,848 | $206.3M | 4.26% | +168,066+4.1% | Added |
| BVF Inc | 3,459,358 | $166.7M | 5.31% | −19,664−0.6% | Reduced |
| Morgan Stanley | 2,305,457 | $111.1M | 0.01% | +217,623+10.4% | Added |
| Price T Rowe Associates Inc | 2,000,696 | $96.4M | 0.01% | +329,558+19.7% | Added |
| Principal Financial Group Inc | 1,753,764 | $84.5M | 0.05% | +469,554+36.6% | Added |
| Driehaus Capital Management LLC | 1,577,356 | $76.0M | 0.56% | −65,088−4.0% | Reduced |
| OrbiMed Advisors LLC | 1,475,403 | $71.1M | 1.62% | +313,600+27.0% | Added |
| American Century Companies Inc | 1,438,031 | $69.3M | 0.04% | +931,072+183.7% | Added |
| Baker Bros. Advisors LP | 1,432,529 | $69.0M | 0.40% | 00.0% | Unchanged |
| Siren, L.L.C. | 1,328,698 | $64.0M | 1.78% | +250,000+23.2% | Added |
| Casdin Capital, LLC | 1,175,000 | $56.6M | 4.29% | 00.0% | Unchanged |
| Capitolis Liquid Global Markets LLC | 1,151,300 | $55.5M | 0.35% | +1,151,300 | New |
| Alliancebernstein L.P. | 638,813 | $44.4M | 0.01% | −210,038−24.7% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 767,993 | $37.0M | 0.44% | 00.0% | Unchanged |
| Pacific Heights Asset Management LLC | 750,000 | $36.1M | 1.21% | +50,000+7.1% | Added |
| Rock Springs Capital Management LP | 640,217 | $30.9M | 1.82% | −108,019−14.4% | Reduced |
| Paradigm Biocapital Advisors LP | 545,287 | $26.3M | 0.54% | +545,287 | New |
| Franklin Resources Inc | 531,595 | $25.6M | 0.01% | −338,987−38.9% | Reduced |
| Logos Global Management LP | 500,000 | $24.1M | 1.24% | −100,000−16.7% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 467,800 | $22.5M | 0.04% | 00.0% | Unchanged |
| BlackRock, Inc. | 441,975 | $21.3M | 0.00% | +11,893+2.8% | Added |
| Standard Life Aberdeen plc | 391,809 | $18.9M | 0.03% | +126,940+47.9% | Added |
| Deutsche Bank AG | 331,867 | $16.0M | 0.01% | −509,295−60.5% | Reduced |
| National Bank of Canada | 305,400 | $14.7M | 0.02% | +40,000+15.1% | Added |
| Balyasny Asset Management LLC | 304,934 | $14.7M | 0.03% | +88,735+41.0% | Added |
| Goldman Sachs Group Inc | 260,543 | $12.6M | 0.00% | +36,211+16.1% | Added |
| Catalio Capital Management, LP | 255,379 | $12.3M | 2.57% | +2,478+1.0% | Added |
| Voloridge Investment Management, LLC | 254,969 | $12.3M | 0.05% | +4,969+2.0% | Added |
| SEB Asset Management AB | 245,043 | $11.8M | 0.05% | +245,043 | New |
| Pentwater Capital Management LP | 245,000 | $11.8M | 0.08% | +245,000 | New |
| Parkman Healthcare Partners LLC | 232,093 | $11.2M | 1.16% | +177,093+322.0% | Added |
| Bank of America Corp | 227,132 | $10.9M | 0.00% | +195,454+617.0% | Added |
| Ameriprise Financial Inc | 219,516 | $10.6M | 0.00% | −66,002−23.1% | Reduced |
| UBS Group AG | 212,919 | $10.3M | 0.00% | +10,442+5.2% | Added |
| Sio Capital Management, LLC | 209,093 | $10.1M | 1.45% | +7,593+3.8% | Added |
| D. E. Shaw & Co., Inc. | 204,790 | $9.87M | 0.01% | +196,167+2,274.9% | Added |
| TD Asset Management Inc | 204,762 | $9.87M | 0.01% | +30,088+17.2% | Added |
| StemPoint Capital LP | 200,267 | $9.65M | 1.86% | −150,806−43.0% | Reduced |
| JPMorgan Chase & Co | 212,803 | $9.35M | 0.00% | +199,847+1,542.5% | Added |
| Woodline Partners LP | 190,808 | $9.20M | 0.03% | +66,906+54.0% | Added |
| ArrowMark Colorado Holdings LLC | 188,195 | $9.07M | 0.24% | −83,018−30.6% | Reduced |
| Two Sigma Investments, LP | 181,415 | $8.74M | 0.01% | +85,872+89.9% | Added |
| Cormorant Asset Management, LP | 175,000 | $8.44M | 0.43% | +175,000 | New |
| Millennium Management LLC | 168,931 | $8.14M | 0.01% | +16,371+10.7% | Added |
| Schonfeld Strategic Advisors LLC | 165,426 | $7.97M | 0.06% | +156,699+1,795.6% | Added |
| Holocene Advisors, LP | 159,009 | $7.66M | 0.02% | +159,009 | New |
| TCG Crossover Management, LLC | 140,411 | $6.77M | 0.19% | −780,446−84.8% | Reduced |
| Eversept Partners, LP | 138,036 | $6.65M | 0.44% | +10,475+8.2% | Added |
| Nomura Asset Management International Inc. | 134,015 | $6.46M | 0.01% | +51,370+62.2% | Added |
| NEXTBio Capital Management LP | 133,239 | $6.42M | 2.98% | +38,796+41.1% | Added |
| SC China Holding Ltd | 266,062 | $6.20M | 0.41% | 00.0% | Unchanged |
| Rhenman & Partners Asset Management AB | 128,100 | $6.17M | 0.76% | −19,500−13.2% | Reduced |
| B Group, Inc. | 127,500 | $6.15M | 4.56% | +37,500+41.7% | Added |
| Davern Capital Partners, LP | 126,461 | $6.10M | 1.67% | +126,461 | New |
| PFM Health Sciences, LP | 126,383 | $6.09M | 0.64% | +58,135+85.2% | Added |
| HighVista Strategies LLC | 123,909 | $5.97M | 1.65% | −69,092−35.8% | Reduced |
| Manufacturers Life Insurance Company, The | 114,814 | $5.53M | 0.00% | +18,427+19.1% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 109,638 | $5.28M | 0.01% | +26,586+32.0% | Added |
| Trexquant Investment LP | 107,884 | $5.20M | 0.04% | +17,939+19.9% | Added |
| Jump Financial, LLC | 107,857 | $5.20M | 0.08% | +107,857 | New |
| Schroder Investment Management Group | 118,225 | $5.19M | 0.00% | +118,225 | New |
| Jones Hill Capital LP | 100,593 | $4.85M | 1.04% | +100,593 | New |
| Birchview Capital, LP | 100,000 | $4.82M | 2.74% | +10,000+11.1% | Added |
| Peregrine Capital Management LLC | 97,117 | $4.68M | 0.17% | +12,793+15.2% | Added |
| Soleus Capital Management, L.P. | 80,000 | $3.86M | 0.16% | −10,000−11.1% | Reduced |
| Tudor Investment Corp Et Al | 75,301 | $3.63M | 0.02% | +40,248+114.8% | Added |
| Boxer Capital Management, LLC | 75,000 | $3.62M | 0.47% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 73,599 | $3.55M | 0.01% | +73,599 | New |
| Diadema Partners LP | 72,234 | $3.48M | 1.44% | +72,234 | New |
| Marshall Wace, LLP | 69,107 | $3.33M | 0.00% | −99,477−59.0% | Reduced |
| Geode Capital Management, LLC | 67,862 | $3.27M | 0.00% | +12,714+23.1% | Added |
| Platinum Investment Management Ltd | 66,864 | $3.22M | 0.81% | −21,010−23.9% | Reduced |
| Jefferies Financial Group Inc. | 62,592 | $3.02M | 0.04% | −40,401−39.2% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 60,517 | $2.92M | 0.04% | −7,572−11.1% | Reduced |
| Burkehill Global Management, LP | 60,000 | $2.89M | 0.14% | 00.0% | Unchanged |
| Alps Advisors Inc | 57,667 | $2.78M | 0.01% | +7,941+16.0% | Added |
| Susquehanna International Group, LLP | 55,842 | $2.69M | 0.00% | +46,843+520.5% | Added |
| Renaissance Technologies LLC | 55,800 | $2.69M | 0.00% | −59,400−51.6% | Reduced |
| Sphera Funds Management Ltd. | 50,800 | $2.45M | 0.42% | +9,800+23.9% | Added |
| Monashee Investment Management LLC | 50,000 | $2.41M | 1.31% | −175,000−77.8% | Reduced |
| Seven Grand Managers, LLC | 50,000 | $2.41M | 0.16% | 00.0% | Unchanged |
| Buckland Partners Management Co LLC | 50,000 | $2.41M | 1.46% | 00.0% | Unchanged |
| Banque Pictet & Cie SA | 49,367 | $2.38M | 0.03% | −10,514−17.6% | Reduced |
| State Street Corp | 47,581 | $2.29M | 0.00% | −643−1.3% | Reduced |
| Pier Capital, LLC | 47,551 | $2.29M | 0.38% | −1,206−2.5% | Reduced |
| DAFNA Capital Management LLC | 46,500 | $2.24M | 0.51% | +9,500+25.7% | Added |
| Brevan Howard Capital Management LP | 47,266 | $2.20M | 0.02% | −39,044−45.2% | Reduced |
| Antipodes Partners Ltd | 45,361 | $2.19M | 0.04% | −930−2.0% | Reduced |
| Raymond James Financial Inc | 45,139 | $2.18M | 0.00% | +751+1.7% | Added |
| Advisor Group Holdings, Inc. | 44,416 | $2.14M | 0.00% | −14,822−25.0% | Reduced |
| Voya Investment Management LLC | 44,410 | $2.14M | 0.00% | −10,890−19.7% | Reduced |
| Bank of Montreal | 39,984 | $1.93M | 0.00% | −14,357−26.4% | Reduced |
| Headlands Technologies LLC | 37,156 | $1.79M | 0.20% | −6,573−15.0% | Reduced |
| Flax Pond Capital, LLC | 36,000 | $1.74M | 1.40% | −12,721−26.1% | Reduced |
| PSquared Asset Management AG | 35,000 | $1.69M | 0.59% | +35,000 | New |
| Mariner, LLC | 34,480 | $1.66M | 0.00% | −9,675−21.9% | Reduced |