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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 192 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

Holders of 5% or more of GPCR

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Structure Therapeutics Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of GPCR
HolderLatest formStakeChangeFirst filedLatest filingFiling
FMR LLC13G/A15.00%32.1M shares+1.80 ppfrom 13.20%Feb 10, 20238 filingsNov 5, 2026SEC
Wellington Management Group LLP13G/A10.10%21.4M shares−1.80 ppfrom 11.90%Feb 6, 20247 filingsFeb 10, 2026SEC
Avoro Capital Advisors LLC13G9.38%16.2M shares–Feb 14, 20243 filingsNov 14, 2025SEC
Janus Henderson Group PLC13G/A7.70%4.45M shares−0.30 ppfrom 8.00%Nov 14, 20245 filingsNov 14, 2025SEC
Deep Track Capital, LP13G/A5.95%12.3M shares−1.37 ppfrom 7.32%Feb 3, 20237 filingsFeb 13, 2026SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

40 Schedule 13D and 13G filings on Structure Therapeutics Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on GPCR
Filed (ET)FilerFormStakeChangeEvent dateFiling
Nov 5, 20261:27 PM ETFMR LLCand 1 other13G/A15.00%32.1M shares+1.80 ppfrom 13.20%Sep 30, 2026SEC
Aug 6, 202610:41 AM ETFMR LLCand 1 other13G/A13.20%28.2M shares−1.80 ppfrom 15.00%Jun 30, 2026SEC
Feb 17, 20264:18 PM ETBiotechnology Value Fund L Pand 9 others13G/A4.90%10.4M shares−0.70 ppfrom 5.60%Below 5%Dec 31, 2025SEC
Feb 13, 20268:46 AM ETDeep Track Capital, LPand 2 others13G/A5.95%12.3M shares−1.37 ppfrom 7.32%Dec 31, 2025SEC
Feb 10, 202611:23 AM ETWellington Management Group LLPand 3 others13G/A10.10%21.4M shares−1.80 ppfrom 11.90%Dec 31, 2025SEC
Feb 5, 20261:40 PM ETFMR LLCand 1 other13G/A15.00%31.1M shares+3.40 ppfrom 11.60%Dec 31, 2025SEC
Nov 14, 202512:07 PM ETJanus Henderson Group PLC13G/A7.70%4.45M shares−0.30 ppfrom 8.00%Sep 30, 2025SEC
Nov 14, 20259:01 AM ETAvoro Capital Advisors LLCand 1 other13G9.38%16.2M shares–Sep 30, 2025SEC
Nov 14, 20258:15 AM ETDeep Track Capital, LPand 2 others13G/A7.32%12.6M shares−1.60 ppfrom 8.92%Sep 30, 2025SEC
Nov 7, 20258:18 AM ETWellington Management Group LLPand 3 others13G/A11.90%20.6M shares+2.00 ppfrom 9.90%Oct 31, 2025SEC
Nov 7, 20258:16 AM ETWellington Management Group LLPand 3 others13G/A9.90%17.1M shares−2.10 ppfrom 12.00%Sep 30, 2025SEC
Aug 18, 20255:02 PM ETBiotechnology Value Fund L Pand 9 others13G5.60%9.61M shares–Aug 11, 2025SEC
Aug 14, 202511:26 AM ETJanus Henderson Group PLC13G/A8.00%4.57M shares+0.40 ppfrom 7.60%Jun 30, 2025SEC
Aug 14, 20258:46 AM ETDeep Track Capital, LPand 2 others13G/A8.92%15.4M shares+1.77 ppfrom 7.15%Jun 30, 2025SEC
Aug 12, 202511:20 AM ETWellington Management Group LLPand 3 others13G/A12.00%20.6M shares–Jun 30, 2025SEC
Aug 6, 202512:14 PM ETFMR LLCand 1 other13G/A11.60%19.9M shares–Jun 30, 2025SEC
May 15, 20258:42 AM ETDeep Track Capital, LPand 2 others13G/A7.15%12.3M shares+1.91 ppfrom 5.24%Mar 31, 2025SEC
May 14, 202512:32 PM ETJanus Henderson Group PLC13G/A7.60%4.36M shares+0.30 ppfrom 7.30%Mar 31, 2025SEC
May 13, 202511:32 AM ETCapital Research Global Investors13G/A3.80%6.49M shares–Below 5%Mar 31, 2025SEC
Feb 14, 202512:22 PM ETJanus Henderson Group PLC13G/A7.30%4.16M shares–Dec 31, 2024SEC
Jan 13, 20254:08 PM ETDeep Track Capital, LPand 2 others13G5.24%9.00M shares–Jan 6, 2025SEC
Nov 14, 2024Janus Henderson Group PLC13GOld format–New–SEC
Nov 14, 2024Ra Capital Management, L.P.13G/AOld format–––SEC
Nov 14, 2024Avoro Capital Advisors LLC13G/AOld format–––SEC
Nov 12, 2024Capital Research Global Investors13GOld format–New–SEC
Nov 12, 2024FMR LLC13G/AOld format–––SEC
Nov 8, 2024Wellington Management Group LLP13G/AOld format–––SEC
May 30, 2024Ra Capital Management, L.P.13GOld format–New–SEC
Feb 14, 2024Deep Track Capital, LP13G/AOld format–––SEC
Feb 14, 2024Avoro Capital Advisors LLC13GOld format–New–SEC
Feb 9, 2024FIL Ltd13G/AOld format–––SEC
Feb 9, 2024FMR LLC13G/AOld format–––SEC
Feb 8, 2024Wellington Management Group LLP13GOld format–––SEC
Feb 6, 2024Wellington Management Group LLP13G/AOld format–––SEC
Dec 20, 2023Biotechnology Value Fund L P13G/AOld format–––SEC
Oct 13, 2023FMR LLC13G/AOld format–––SEC
Feb 13, 2023Biotechnology Value Fund L P13GOld format–New–SEC
Feb 10, 2023FIL Ltd13GOld format–New–SEC
Feb 10, 2023FMR LLC13GOld format–New–SEC
Feb 3, 2023Deep Track Capital, LP13GOld format–New–SEC

Form 144: proposed insider sales

4 notices from officers, directors and other affiliates planning to sell Structure Therapeutics Inc. shares, newest first.

Form 144 notices for GPCR
Filed (ET)SellerShares to sellMarket valuePlanned saleBrokerFiling
Sep 21, 20264:35 PM ETBlas Coll CrespoOfficer4.01K$140.3KSep 21, 202610b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
Jun 25, 20264:27 PM ETXichen LinOfficer35.5K$1.71MJun 25, 202610b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
Jun 10, 20245:07 PM ETRaymond C StevensOfficer185.0K$9.77MJun 10, 2024Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
Jun 3, 20244:58 PM ETXichen LinOfficer59.0K$2.02MJun 3, 202410b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC