Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Structure Therapeutics Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 173
- +22 vs. Q1 2025
- Shares held
- 54.8M
- −1.57M (−2.8%) vs. Q1 2025
- Total value
- $1.14B
- +$147.5M (+14.9%) vs. Q1 2025
- New holders
- 38
- 63 more added
- Sold out
- 16
- 44 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wellington Management Group LLP | 6,875,769 | $142.6M | 0.03% | −915,414−11.7% | Reduced |
| Deep Track Capital, LP | 5,133,917 | $106.5M | 3.42% | +1,033,917+25.2% | Added |
| FMR LLC | 4,914,965 | $101.9M | 0.01% | −968,742−16.5% | Reduced |
| Janus Henderson Group PLC | 4,573,006 | $94.9M | 0.05% | +217,812+5.0% | Added |
| Baker Bros. Advisors LP | 2,508,767 | $52.0M | 0.50% | +2,147,202+593.9% | Added |
| BVF Inc | 1,771,417 | $36.7M | 1.31% | 00.0% | Unchanged |
| Capital International Investors | 1,618,876 | $33.6M | 0.01% | −1500.0% | Reduced |
| Ameriprise Financial Inc | 1,588,198 | $32.9M | 0.01% | +106,389+7.2% | Added |
| Ra Capital Management, L.P. | 1,517,418 | $31.5M | 0.53% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,328,479 | $27.6M | 0.02% | +336,139+33.9% | Added |
| Casdin Capital, LLC | 1,225,000 | $25.4M | 2.31% | +525,000+75.0% | Added |
| Millennium Management LLC | 1,220,055 | $25.3M | 0.02% | +429,896+54.4% | Added |
| Vestal Point Capital, LP | 1,200,000 | $24.9M | 1.31% | −588,990−32.9% | Reduced |
| OrbiMed Advisors LLC | 1,199,300 | $24.9M | 0.63% | +547,272+83.9% | Added |
| Rock Springs Capital Management LP | 1,135,879 | $23.6M | 1.47% | +2,900+0.3% | Added |
| TCG Crossover Management, LLC | 1,063,000 | $22.0M | 2.52% | 00.0% | Unchanged |
| Morgan Stanley | 917,346 | $19.0M | 0.00% | +224,907+32.5% | Added |
| Principal Financial Group Inc | 853,202 | $17.7M | 0.01% | +96,495+12.8% | Added |
| Logos Global Management LP | 850,000 | $17.6M | 2.35% | +425,000+100.0% | Added |
| Franklin Resources Inc | 741,783 | $15.4M | 0.00% | +1,631+0.2% | Added |
| Driehaus Capital Management LLC | 672,792 | $14.0M | 0.11% | −599,951−47.1% | Reduced |
| Catalio Capital Management, LP | 670,575 | $13.9M | 2.92% | −34,289−4.9% | Reduced |
| American Century Companies Inc | 491,193 | $10.2M | 0.01% | −19,008−3.7% | Reduced |
| Federated Hermes, Inc. | 468,300 | $9.71M | 0.02% | −702,648−60.0% | Reduced |
| Pacific Heights Asset Management LLC | 460,000 | $9.54M | 0.51% | +460,000 | New |
| Monashee Investment Management LLC | 430,000 | $8.92M | 4.71% | +137,138+46.8% | Added |
| Invesco Ltd. | 424,548 | $8.81M | 0.00% | +30,162+7.6% | Added |
| Standard Life Aberdeen plc | 401,624 | $8.33M | 0.01% | +152,725+61.4% | Added |
| Handelsbanken Fonder AB | 380,000 | $7.88M | 0.03% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 373,407 | $7.74M | 0.14% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 352,868 | $7.32M | 0.00% | −424,305−54.6% | Reduced |
| Bellevue Group AG | 348,527 | $7.23M | 0.16% | +126,812+57.2% | Added |
| Point72 Asset Management, L.P. | 330,000 | $6.84M | 0.02% | +100,569+43.8% | Added |
| Schonfeld Strategic Advisors LLC | 321,591 | $6.67M | 0.05% | +321,591 | New |
| ArrowMark Colorado Holdings LLC | 298,937 | $6.20M | 0.11% | +53,751+21.9% | Added |
| SC China Holding Ltd | 266,062 | $5.52M | 0.28% | 00.0% | Unchanged |
| BlackRock, Inc. | 243,334 | $5.05M | 0.00% | −323,171−57.0% | Reduced |
| Goldman Sachs Group Inc | 220,174 | $4.57M | 0.00% | −104,261−32.1% | Reduced |
| Foresite Capital Management VI LLC | 210,000 | $4.36M | 2.45% | −210,000−50.0% | Reduced |
| Pier Capital, LLC | 198,478 | $4.12M | 0.63% | −14,042−6.6% | Reduced |
| Schroder Investment Management Group | 187,805 | $3.90M | 0.00% | −288,331−60.6% | Reduced |
| Ikarian Capital, LLC | 183,085 | $3.80M | 1.26% | −81,000−30.7% | Reduced |
| Readystate Asset Management LP | 178,612 | $3.70M | 0.15% | −302,629−62.9% | Reduced |
| Woodline Partners LP | 176,453 | $3.66M | 0.02% | +1,029+0.6% | Added |
| Marshall Wace, LLP | 176,060 | $3.65M | 0.00% | +145,434+474.9% | Added |
| Silverarc Capital Management, LLC | 175,636 | $3.64M | 0.75% | −12,433−6.6% | Reduced |
| Nantahala Capital Management, LLC | 168,553 | $3.50M | 0.25% | 00.0% | Unchanged |
| Canada Pension Plan Investment Board | 167,800 | $3.48M | 0.00% | +167,800 | New |
| UBS Group AG | 152,981 | $3.17M | 0.00% | −85,216−35.8% | Reduced |
| CCG Wealth Management, LLC | 150,000 | $3.11M | 1.64% | 00.0% | Unchanged |
| Susquehanna Fundamental Investments, LLC | 139,717 | $2.90M | 0.08% | −18,244−11.5% | Reduced |
| Rhenman & Partners Asset Management AB | 135,100 | $2.80M | 0.35% | +65,100+93.0% | Added |
| First Light Asset Management, LLC | 122,226 | $2.53M | 0.33% | −10,154−7.7% | Reduced |
| Point72 Europe (London) LLP | 116,697 | $2.42M | 0.12% | +26,000+28.7% | Added |
| Renaissance Technologies LLC | 111,900 | $2.32M | 0.00% | +96,100+608.2% | Added |
| Eversept Partners, LP | 99,338 | $2.06M | 0.21% | +99,338 | New |
| Sphera Funds Management Ltd. | 95,931 | $1.99M | 0.52% | +11,931+14.2% | Added |
| HighVista Strategies LLC | 86,621 | $1.80M | 0.66% | +69,060+393.3% | Added |
| Trexquant Investment LP | 81,588 | $1.69M | 0.02% | −38,752−32.2% | Reduced |
| Susquehanna International Group, LLP | 75,802 | $1.57M | 0.00% | +7,635+11.2% | Added |
| Platinum Investment Management Ltd | 74,900 | $1.55M | 0.10% | 00.0% | Unchanged |
| Verition Fund Management LLC | 72,984 | $1.51M | 0.01% | +53,402+272.7% | Added |
| Cubist Systematic Strategies, LLC | 71,690 | $1.49M | 0.02% | +16,874+30.8% | Added |
| Banque Pictet & Cie SA | 70,401 | $1.46M | 0.02% | −11,365−13.9% | Reduced |
| Jain Global LLC | 69,369 | $1.44M | 0.02% | +45,730+193.5% | Added |
| BNP Paribas Arbitrage, SA | 65,836 | $1.37M | 0.00% | +61,318+1,357.2% | Added |
| Advisor Group Holdings, Inc. | 63,362 | $1.31M | 0.00% | +31,972+101.9% | Added |
| Jump Financial, LLC | 63,234 | $1.31M | 0.02% | +32,524+105.9% | Added |
| Exchange Traded Concepts, LLC | 61,732 | $1.28M | 0.02% | +22,809+58.6% | Added |
| Bank of Montreal | 58,073 | $1.22M | 0.00% | +4,838+9.1% | Added |
| DAFNA Capital Management LLC | 59,000 | $1.22M | 0.34% | 00.0% | Unchanged |
| Macquarie Group Ltd | 58,000 | $1.20M | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 57,622 | $1.20M | 0.04% | −19,672−25.5% | Reduced |
| PFM Health Sciences, LP | 56,594 | $1.17M | 0.10% | +16,194+40.1% | Added |
| Geode Capital Management, LLC | 54,181 | $1.12M | 0.00% | +8,444+18.5% | Added |
| Exome Asset Management LLC | 53,744 | $1.11M | 0.92% | −49,200−47.8% | Reduced |
| Sectoral Asset Management Inc | 51,369 | $1.07M | 0.70% | +17,674+52.5% | Added |
| TD Asset Management Inc | 43,686 | $906.0K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 42,442 | $880.2K | 0.00% | −91,797−68.4% | Reduced |
| Quinn Opportunity Partners LLC | 42,000 | $871.1K | 0.07% | +20,000+90.9% | Added |
| Manufacturers Life Insurance Company, The | 40,789 | $846.0K | 0.00% | +52+0.1% | Added |
| Susquehanna Portfolio Strategies, LLC | 39,960 | $828.8K | 0.02% | +39,960 | New |
| Mariner, LLC | 39,501 | $819.3K | 0.00% | +21,450+118.8% | Added |
| Walleye Capital LLC | 38,673 | $802.1K | 0.01% | +38,673 | New |
| TrueMark Investments, LLC | 37,765 | $783.2K | 0.17% | −1,452−3.7% | Reduced |
| Two Sigma Advisers, LP | 36,100 | $748.7K | 0.00% | +36,100 | New |
| Birchview Capital, LP | 36,000 | $746.6K | 0.74% | +36,000 | New |
| Sofinnova Investments, Inc. | 34,353 | $712.5K | 0.05% | −599−1.7% | Reduced |
| State Street Corp | 33,459 | $693.9K | 0.00% | +22,719+211.5% | Added |
| Alps Advisors Inc | 31,073 | $644.5K | 0.00% | −12,007−27.9% | Reduced |
| Voya Investment Management LLC | 30,655 | $635.8K | 0.00% | +4,715+18.2% | Added |
| Caption Management, LLC | 28,174 | $584.3K | 0.05% | +18,918+204.4% | Added |
| Nomura Asset Management Co Ltd | 24,874 | $515.9K | 0.00% | −4,100−14.2% | Reduced |
| DCF Advisers, LLC | 24,750 | $513.3K | 0.25% | +24,750 | New |
| Omers Administration Corp | 24,600 | $510.2K | 0.00% | +24,600 | New |
| Simplex Trading, LLC | 23,094 | $478.0K | 0.01% | +2,490+12.1% | Added |
| NEOS Investment Management LLC | 22,880 | $474.5K | 0.01% | +290+1.3% | Added |
| Tema ETFs LLC | 22,880 | $474.5K | 0.13% | +290+1.3% | Added |
| Alliancebernstein L.P. | 22,499 | $466.6K | 0.00% | +22,499 | New |
| Tejara Capital Ltd | 22,400 | $464.6K | 0.22% | +22,400 | New |