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Livermore
ZHEN

Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Structure Therapeutics Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
173
+22 vs. Q1 2025
Shares held
54.8M
−1.57M (−2.8%) vs. Q1 2025
Total value
$1.14B
+$147.5M (+14.9%) vs. Q1 2025
New holders
38
63 more added
Sold out
16
44 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 173 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 38 institutionsQ2 2023: 48 institutionsQ3 2023: 84 institutionsQ4 2023: 122 institutionsQ1 2024: 119 institutionsQ2 2024: 167 institutionsQ3 2024: 161 institutionsQ4 2024: 165 institutionsQ1 2025: 151 institutionsQ2 2025: 173 institutionsQ3 2025: 158 institutionsQ4 2025: 199 institutionsQ1 2026: 198 institutionsQ2 2026: 191 institutions
Value heldQ2 2025: $1.14B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $346.2MQ2 2023: $699.4MQ3 2023: $1.64BQ4 2023: $1.74BQ1 2024: $1.86BQ2 2024: $2.33BQ3 2024: $2.69BQ4 2024: $1.65BQ1 2025: $990.0MQ2 2025: $1.14BQ3 2025: $1.59BQ4 2025: $4.58BQ1 2026: $3.23BQ2 2026: $3.62B
Institutions holding GPCR and their total value by quarter
QuarterHoldersValue
Q2 2026191$3.62B
Q1 2026198$3.23B
Q4 2025199$4.58B
Q3 2025158$1.59B
Q2 2025173$1.14B
Q1 2025151$990.0M
Q4 2024165$1.65B
Q3 2024161$2.69B
Q2 2024167$2.33B
Q1 2024119$1.86B
Q4 2023122$1.74B
Q3 202384$1.64B
Q2 202348$699.4M
Q1 202338$346.2M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q1 2025.

Institutions holding GPCR in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Headlands Technologies LLC22,338$463.3K0.06%+18,930+555.5%Added
Paloma Partners Management Co20,950$434.5K0.10%+20,950New
SG Americas Securities, LLC19,239$399.0K0.00%+19,239New
Teachers Retirement System of the State of Kentucky17,651$366.0K0.00%00.0%Unchanged
Prelude Capital Management, LLC17,070$354.0K0.03%−8,558−33.4%Reduced
Quadrature Capital Ltd16,079$333.8K0.01%+16,079New
Engineers Gate Manager LP15,862$329.0K0.00%+15,862New
Squarepoint Ops LLC15,176$314.8K0.00%+15,176New
ADAR1 Capital Management, LLC15,000$311.1K0.05%−20,619−57.9%Reduced
Good Life Advisors, LLC15,000$311.1K0.02%+2,000+15.4%Added
Virtu Financial LLC14,779$307.0K0.02%+14,779New
Capital Fund Management S.A.14,350$297.6K0.00%−65,306−82.0%Reduced
Bank of America Corp13,908$288.5K0.00%−41,530−74.9%Reduced
Maso Capital Partners Ltd13,000$269.6K0.48%+13,000New
D. E. Shaw & Co., Inc.12,165$252.3K0.00%+504+4.3%Added
China Universal Asset Management Co., Ltd.11,967$248.2K0.02%+16+0.1%Added
Universal- Beteiligungs- und Servicegesellschaft mbH11,914$247.1K0.00%−64,949−84.5%Reduced
LPL Financial LLC11,599$240.6K0.00%+11,599New
Griffin Asset Management, Inc.11,205$232.4K0.03%+11,205New
Brandywine Managers, LLC11,057$229.3K0.23%00.0%Unchanged
Atom Investors LP11,027$228.7K0.02%+11,027New
Allianz Asset Management GmbH11,000$228.1K0.00%+11,000New
Envestnet Asset Management Inc10,676$221.4K0.00%+10,676New
DnB Asset Management AS10,635$220.6K0.00%+10,635New
Bleichroeder LP10,000$207.4K0.05%00.0%Unchanged
PEAK6 LLC9,445$195.9K0.01%00.0%Unchanged
Parallel Advisors, LLC8,264$171.4K0.00%+8,264New
Group One Trading, L.P.8,065$167.3K0.01%−40,852−83.5%Reduced
Royal Bank of Canada7,582$157.0K0.00%+3,871+104.3%Added
Wells Fargo & Company7,223$149.8K0.00%−122−1.7%Reduced
Signaturefd, LLC6,650$137.9K0.00%+6,550+6,550.0%Added
Barclays PLC6,328$131.2K0.00%+1,016+19.1%Added
Raymond James Financial Inc6,229$129.2K0.00%+6,229New
The PNC Financial Services Group, Inc.4,415$91.6K0.00%+994+29.1%Added
Virtus Investment Advisers, Inc.4,232$87.8K0.03%−945−18.3%Reduced
UBS Asset Management Americas Inc4,170$86.5K0.00%−1,745−29.5%Reduced
Mirae Asset Global Investments Co., Ltd.4,120$85.4K0.00%+435+11.8%Added
Antipodes Partners Ltd2,932$60.8K0.00%−1,315−31.0%Reduced
Quantbot Technologies LP2,888$59.9K0.00%−11,513−79.9%Reduced
Assetmark, Inc2,877$59.7K0.00%+820+39.9%Added
Steward Partners Investment Advisory, LLC2,640$54.8K0.00%+124+4.9%Added
FNY Investment Advisers, LLC1,700$35.0K0.01%+500+41.7%Added
Citigroup Inc1,600$33.2K0.00%−103,375−98.5%Reduced
GF Fund Management Co. Ltd.1,525$31.6K0.00%00.0%Unchanged
State of Wyoming1,330$27.6K0.00%+1,330New
Tower Research Capital LLC (TRC)898$18.6K0.00%+303+50.9%Added
Caitong International Asset Management Co., Ltd835$17.3K0.01%+459+122.1%Added
Jones Financial Companies LLLP767$16.2K0.00%−2,379−75.6%Reduced
Farther Finance Advisors, LLC670$13.9K0.00%+670New
Dynamic Wealth Strategies, LLC550$11.4K0.01%+550New
South State Corp.500$10.4K0.00%+500New
Country Trust Bank500$10.4K0.00%+500New
GAMMA Investing LLC481$9.98K0.00%−26−5.1%Reduced
Rhumbline Advisers450$9.33K0.00%00.0%Unchanged
CWM, LLC355$7.00K0.00%+255+255.0%Added
North Star Investment Management Corp.330$6.84K0.00%00.0%Unchanged
Wolff Wiese Magana LLC286$5.93K0.00%+152+113.4%Added
Daiwa Securities Group Inc.226$5.00K0.00%00.0%Unchanged
National Bank of Canada200$4.15K0.00%−2,757−93.2%Reduced
Private Wealth Management Group, LLC196$4.07K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC170$3.53K0.00%+170New
Ameritas Advisory Services, LLC100$2.07K0.00%+100New
Northwestern Mutual Wealth Management Co58$1.20K0.00%+58New
Washington Trust Advisors, Inc.41$8500.00%00.0%Unchanged
CIBC Private Wealth Group, LLC33$6840.00%+33New
Skopos Labs, Inc.32$6640.00%+32New
Federation des caisses Desjardins du Quebec20$4150.00%00.0%Unchanged
US Bancorp13$2700.00%00.0%Unchanged
MAI Capital Management10$2080.00%00.0%Unchanged
Global Retirement Partners, LLC10$2070.00%+10New
Cullen/Frost Bankers, Inc.8$1660.00%00.0%Unchanged
Huntington National Bank2$410.00%00.0%Unchanged
Point72 Asia (Singapore) Pte. Ltd.1$210.00%00.0%Unchanged
Capital Research Global Investors0$00.00%−2,164,145−100.0%Sold out
FIL Ltd0$00.00%−1,150,440−100.0%Sold out
Camber Capital Management LP0$00.00%−300,000−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−214,063−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−202,483−100.0%Sold out
Jane Street Group, LLC0$00.00%−120,703−100.0%Sold out
Zimmer Partners, LP0$00.00%−100,776−100.0%Sold out
Wexford Capital LP0$00.00%−30,102−100.0%Sold out
HRT Financial LP0$00.00%−22,859−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−11,908−100.0%Sold out
Penserra Capital Management LLC0$00.00%−3,411−100.0%Sold out
Boston Private Wealth LLC0$00.00%−836−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−77−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−67−100.0%Sold out
Mather Group, LLC.0$00.00%−35−100.0%Sold out
Larson Financial Group LLC0$00.00%−9−100.0%Sold out