Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Structure Therapeutics Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 151
- −13 vs. Q4 2024
- Shares held
- 56.4M
- −4.53M (−7.4%) vs. Q4 2024
- Total value
- $990.0M
- −$662.8M (−40.1%) vs. Q4 2024
- New holders
- 23
- 47 more added
- Sold out
- 36
- 50 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wellington Management Group LLP | 7,791,183 | $134.9M | 0.03% | +5,569+0.1% | Added |
| FMR LLC | 5,883,707 | $101.8M | 0.01% | −195,039−3.2% | Reduced |
| Janus Henderson Group PLC | 4,355,194 | $86.1M | 0.05% | +195,306+4.7% | Added |
| Deep Track Capital, LP | 4,100,000 | $71.0M | 2.30% | +1,300,000+46.4% | Added |
| Capital Research Global Investors | 2,164,145 | $37.5M | 0.01% | −1,373,196−38.8% | Reduced |
| Vestal Point Capital, LP | 1,788,990 | $31.0M | 2.21% | +63,990+3.7% | Added |
| BVF Inc | 1,771,417 | $30.7M | 1.25% | 00.0% | Unchanged |
| Capital International Investors | 1,619,026 | $28.0M | 0.01% | −550.0% | Reduced |
| Ra Capital Management, L.P. | 1,517,418 | $26.3M | 0.44% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 1,481,809 | $25.7M | 0.01% | +61,757+4.3% | Added |
| Driehaus Capital Management LLC | 1,272,743 | $22.0M | 0.21% | −784,667−38.1% | Reduced |
| Federated Hermes, Inc. | 1,170,948 | $20.3M | 0.04% | −875,010−42.8% | Reduced |
| FIL Ltd | 1,150,440 | $19.9M | 0.02% | −149,575−11.5% | Reduced |
| Rock Springs Capital Management LP | 1,132,979 | $19.6M | 1.12% | +52,016+4.8% | Added |
| TCG Crossover Management, LLC | 1,063,000 | $18.4M | 2.51% | 00.0% | Unchanged |
| Citadel Advisors LLC | 992,340 | $17.2M | 0.02% | −486,999−32.9% | Reduced |
| Millennium Management LLC | 790,159 | $13.7M | 0.01% | +39,146+5.2% | Added |
| Price T Rowe Associates Inc | 777,173 | $13.5M | 0.00% | −617,133−44.3% | Reduced |
| Principal Financial Group Inc | 756,707 | $13.1M | 0.01% | −34,427−4.4% | Reduced |
| Franklin Resources Inc | 740,152 | $12.8M | 0.00% | +2,062+0.3% | Added |
| Catalio Capital Management, LP | 704,864 | $12.2M | 3.02% | +135,469+23.8% | Added |
| Casdin Capital, LLC | 700,000 | $12.1M | 0.99% | 00.0% | Unchanged |
| Morgan Stanley | 692,439 | $12.0M | 0.00% | +305,263+78.8% | Added |
| OrbiMed Advisors LLC | 652,028 | $11.3M | 0.27% | 00.0% | Unchanged |
| BlackRock, Inc. | 566,505 | $9.81M | 0.00% | −44,080−7.2% | Reduced |
| Schroder Investment Management Group | 476,136 | $9.41M | 0.01% | +200,825+72.9% | Added |
| American Century Companies Inc | 510,201 | $8.83M | 0.01% | −102,415−16.7% | Reduced |
| Readystate Asset Management LP | 481,241 | $8.33M | 0.42% | +271,899+129.9% | Added |
| Logos Global Management LP | 425,000 | $7.36M | 1.31% | −275,000−39.3% | Reduced |
| Foresite Capital Management VI LLC | 420,000 | $7.27M | 3.98% | 00.0% | Unchanged |
| Invesco Ltd. | 394,386 | $6.83M | 0.00% | +22,619+6.1% | Added |
| Handelsbanken Fonder AB | 380,000 | $6.58M | 0.03% | +215,000+130.3% | Added |
| Deerfield Management Company, L.P. (Series C) | 373,407 | $6.46M | 0.13% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 361,565 | $6.26M | 0.07% | 00.0% | Unchanged |
| SC China Holding Ltd | 266,062 | $6.20M | 0.36% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 324,435 | $5.62M | 0.00% | −258,430−44.3% | Reduced |
| Camber Capital Management LP | 300,000 | $5.19M | 0.32% | 00.0% | Unchanged |
| Monashee Investment Management LLC | 292,862 | $5.07M | 0.60% | +160,862+121.9% | Added |
| Ikarian Capital, LLC | 264,085 | $4.57M | 1.49% | −20,000−7.0% | Reduced |
| Standard Life Aberdeen plc | 248,899 | $4.31M | 0.01% | +77,511+45.2% | Added |
| ArrowMark Colorado Holdings LLC | 245,186 | $4.24M | 0.07% | +12,277+5.3% | Added |
| UBS Group AG | 238,197 | $4.12M | 0.00% | −5,866−2.4% | Reduced |
| Point72 Asset Management, L.P. | 229,431 | $3.97M | 0.01% | −247,267−51.9% | Reduced |
| Bellevue Group AG | 221,715 | $3.84M | 0.09% | −263,335−54.3% | Reduced |
| Candriam Luxembourg S.C.A. | 214,063 | $3.71M | 0.02% | −1,358−0.6% | Reduced |
| Pier Capital, LLC | 212,520 | $3.68M | 0.62% | +79,916+60.3% | Added |
| Balyasny Asset Management LLC | 202,483 | $3.50M | 0.01% | +202,483 | New |
| Silverarc Capital Management, LLC | 188,069 | $3.26M | 0.68% | +35,674+23.4% | Added |
| Woodline Partners LP | 175,424 | $3.04M | 0.02% | −158,477−47.5% | Reduced |
| Nantahala Capital Management, LLC | 168,553 | $2.92M | 0.24% | −52,447−23.7% | Reduced |
| Susquehanna Fundamental Investments, LLC | 157,961 | $2.73M | 0.05% | +157,961 | New |
| CCG Wealth Management, LLC | 150,000 | $2.60M | 1.55% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 134,239 | $2.32M | 0.00% | +101,924+315.4% | Added |
| First Light Asset Management, LLC | 132,380 | $2.29M | 0.26% | −266,475−66.8% | Reduced |
| Jane Street Group, LLC | 120,703 | $2.09M | 0.00% | +4,690+4.0% | Added |
| Trexquant Investment LP | 120,340 | $2.08M | 0.02% | +67,464+127.6% | Added |
| Citigroup Inc | 104,975 | $1.82M | 0.00% | +30,891+41.7% | Added |
| Exome Asset Management LLC | 102,944 | $1.78M | 1.60% | −49,021−32.3% | Reduced |
| Zimmer Partners, LP | 100,776 | $1.74M | 0.04% | +43,876+77.1% | Added |
| Point72 Europe (London) LLP | 90,697 | $1.57M | 0.11% | +59,277+188.7% | Added |
| Sphera Funds Management Ltd. | 84,000 | $1.45M | 0.36% | +84,000 | New |
| Banque Pictet & Cie SA | 81,766 | $1.42M | 0.02% | +7,589+10.2% | Added |
| Capital Fund Management S.A. | 79,656 | $1.38M | 0.02% | +12,521+18.7% | Added |
| Boothbay Fund Management, LLC | 77,294 | $1.34M | 0.05% | −5,854−7.0% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 76,863 | $1.33M | 0.00% | −37,129−32.6% | Reduced |
| Platinum Investment Management Ltd | 74,900 | $1.30M | 0.08% | 00.0% | Unchanged |
| Rhenman & Partners Asset Management AB | 70,000 | $1.21M | 0.14% | +70,000 | New |
| Susquehanna International Group, LLP | 68,167 | $1.18M | 0.00% | −36−0.1% | Reduced |
| DAFNA Capital Management LLC | 59,000 | $1.02M | 0.29% | +23,500+66.2% | Added |
| Macquarie Group Ltd | 58,000 | $1.00M | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 55,438 | $959.6K | 0.00% | +1,253+2.3% | Added |
| Cubist Systematic Strategies, LLC | 54,816 | $948.9K | 0.01% | +54,816 | New |
| Bank of Montreal | 53,235 | $921.5K | 0.00% | +3,062+6.1% | Added |
| Group One Trading, L.P. | 48,917 | $846.8K | 0.04% | +27,350+126.8% | Added |
| Geode Capital Management, LLC | 45,737 | $791.7K | 0.00% | +32+0.1% | Added |
| TD Asset Management Inc | 43,686 | $756.2K | 0.00% | −45,196−50.8% | Reduced |
| Alps Advisors Inc | 43,080 | $745.7K | 0.00% | −3,220−7.0% | Reduced |
| Manufacturers Life Insurance Company, The | 40,737 | $705.2K | 0.00% | −17,505−30.1% | Reduced |
| PFM Health Sciences, LP | 40,400 | $699.3K | 0.05% | +40,400 | New |
| TrueMark Investments, LLC | 39,217 | $678.8K | 0.18% | −2,910−6.9% | Reduced |
| Exchange Traded Concepts, LLC | 38,923 | $673.8K | 0.01% | −1,512−3.7% | Reduced |
| ADAR1 Capital Management, LLC | 35,619 | $616.6K | 0.12% | +300+0.8% | Added |
| Sofinnova Investments, Inc. | 34,952 | $605.0K | 0.05% | +14,060+67.3% | Added |
| Sectoral Asset Management Inc | 33,695 | $583.3K | 0.45% | −15,555−31.6% | Reduced |
| Advisor Group Holdings, Inc. | 31,390 | $543.3K | 0.00% | +598+1.9% | Added |
| Jump Financial, LLC | 30,710 | $531.6K | 0.01% | +30,710 | New |
| Marshall Wace, LLP | 30,626 | $530.1K | 0.00% | −552,581−94.7% | Reduced |
| Wexford Capital LP | 30,102 | $521.1K | 0.14% | −51,770−63.2% | Reduced |
| Nomura Asset Management Co Ltd | 28,974 | $501.5K | 0.00% | −7,951−21.5% | Reduced |
| Voya Investment Management LLC | 25,940 | $449.0K | 0.00% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 25,628 | $443.6K | 0.04% | −6,372−19.9% | Reduced |
| Jain Global LLC | 23,639 | $409.2K | 0.01% | +23,639 | New |
| HRT Financial LP | 22,859 | $395.0K | 0.00% | +22,859 | New |
| NEOS Investment Management LLC | 22,590 | $391.0K | 0.01% | −21,753−49.1% | Reduced |
| Tema ETFs LLC | 22,590 | $391.0K | 0.12% | −21,753−49.1% | Reduced |
| Quinn Opportunity Partners LLC | 22,000 | $380.8K | 0.03% | +10,000+83.3% | Added |
| Simplex Trading, LLC | 20,604 | $356.0K | 0.01% | +3,258+18.8% | Added |
| Verition Fund Management LLC | 19,582 | $339.0K | 0.00% | +19,582 | New |
| Mariner, LLC | 18,051 | $312.5K | 0.00% | −6,479−26.4% | Reduced |
| Teachers Retirement System of the State of Kentucky | 17,651 | $306.0K | 0.00% | 00.0% | Unchanged |