Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Structure Therapeutics Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 151
- −13 vs. Q4 2024
- Shares held
- 56.4M
- −4.53M (−7.4%) vs. Q4 2024
- Total value
- $990.0M
- −$662.8M (−40.1%) vs. Q4 2024
- New holders
- 23
- 47 more added
- Sold out
- 36
- 50 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Point72 Asia (Singapore) Pte. Ltd. | 1 | $17 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 2 | $35 | 0.00% | 00.0% | Unchanged |
| Cullen/Frost Bankers, Inc. | 8 | $138 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 9 | $156 | 0.00% | +9 | New |
| MAI Capital Management | 10 | $174 | 0.00% | +10 | New |
| US Bancorp | 13 | $225 | 0.00% | −88−87.1% | Reduced |
| Federation des caisses Desjardins du Quebec | 20 | $346 | 0.00% | 00.0% | Unchanged |
| Mather Group, LLC. | 35 | $606 | 0.00% | +35 | New |
| Washington Trust Advisors, Inc. | 41 | $710 | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 67 | $1.16K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 77 | $1.33K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 100 | $1.73K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 100 | $2.00K | 0.00% | 00.0% | Unchanged |
| Wolff Wiese Magana LLC | 134 | $2.32K | 0.00% | +134 | New |
| Private Wealth Management Group, LLC | 196 | $3.39K | 0.00% | +196 | New |
| Daiwa Securities Group Inc. | 226 | $4.00K | 0.00% | 00.0% | Unchanged |
| North Star Investment Management Corp. | 330 | $5.71K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 376 | $6.51K | 0.00% | +190+102.2% | Added |
| Rhumbline Advisers | 450 | $7.79K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 507 | $8.78K | 0.00% | −642−55.9% | Reduced |
| Tower Research Capital LLC (TRC) | 595 | $10.3K | 0.00% | −3,481−85.4% | Reduced |
| Boston Private Wealth LLC | 836 | $14.5K | 0.00% | +836 | New |
| FNY Investment Advisers, LLC | 1,200 | $20.0K | 0.01% | −300−20.0% | Reduced |
| GF Fund Management Co. Ltd. | 1,525 | $26.4K | 0.00% | +274+21.9% | Added |
| Assetmark, Inc | 2,057 | $35.6K | 0.00% | −214−9.4% | Reduced |
| Steward Partners Investment Advisory, LLC | 2,516 | $43.6K | 0.00% | +402+19.0% | Added |
| National Bank of Canada | 2,957 | $51.1K | 0.00% | +2,766+1,448.2% | Added |
| Headlands Technologies LLC | 3,408 | $59.0K | 0.01% | −752−18.1% | Reduced |
| Penserra Capital Management LLC | 3,411 | $59.0K | 0.00% | +304+9.8% | Added |
| The PNC Financial Services Group, Inc. | 3,421 | $59.2K | 0.00% | +144+4.4% | Added |
| Jones Financial Companies LLLP | 3,146 | $62.2K | 0.00% | −1,082−25.6% | Reduced |
| Royal Bank of Canada | 3,711 | $64.0K | 0.00% | −121,981−97.0% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 3,685 | $72.9K | 0.00% | +119+3.3% | Added |
| Antipodes Partners Ltd | 4,247 | $73.5K | 0.00% | +3,213+310.7% | Added |
| BNP Paribas Arbitrage, SA | 4,518 | $78.2K | 0.00% | −6,700−59.7% | Reduced |
| Virtus Investment Advisers, Inc. | 5,177 | $89.6K | 0.02% | +5,177 | New |
| Barclays PLC | 5,312 | $92.0K | 0.00% | −110,359−95.4% | Reduced |
| UBS Asset Management Americas Inc | 5,915 | $102.4K | 0.00% | +5,915 | New |
| Wells Fargo & Company | 7,345 | $127.1K | 0.00% | −2,758−27.3% | Reduced |
| Caption Management, LLC | 9,256 | $160.2K | 0.01% | +3,656+65.3% | Added |
| PEAK6 LLC | 9,445 | $163.5K | 0.01% | 00.0% | Unchanged |
| Bleichroeder LP | 10,000 | $173.1K | 0.05% | 00.0% | Unchanged |
| State Street Corp | 10,740 | $185.9K | 0.00% | +213+2.0% | Added |
| Brandywine Managers, LLC | 11,057 | $191.4K | 0.23% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 11,661 | $201.9K | 0.00% | +11,661 | New |
| Graham Capital Management, L.P. | 11,908 | $206.1K | 0.01% | +11,908 | New |
| China Universal Asset Management Co., Ltd. | 11,951 | $206.9K | 0.02% | −683−5.4% | Reduced |
| Good Life Advisors, LLC | 13,000 | $225.0K | 0.02% | +13,000 | New |
| Quantbot Technologies LP | 14,401 | $249.3K | 0.01% | +14,401 | New |
| Renaissance Technologies LLC | 15,800 | $273.5K | 0.00% | +15,800 | New |
| HighVista Strategies LLC | 17,561 | $304.0K | 0.12% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 17,651 | $306.0K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 18,051 | $312.5K | 0.00% | −6,479−26.4% | Reduced |
| Verition Fund Management LLC | 19,582 | $339.0K | 0.00% | +19,582 | New |
| Simplex Trading, LLC | 20,604 | $356.0K | 0.01% | +3,258+18.8% | Added |
| Quinn Opportunity Partners LLC | 22,000 | $380.8K | 0.03% | +10,000+83.3% | Added |
| NEOS Investment Management LLC | 22,590 | $391.0K | 0.01% | −21,753−49.1% | Reduced |
| Tema ETFs LLC | 22,590 | $391.0K | 0.12% | −21,753−49.1% | Reduced |
| HRT Financial LP | 22,859 | $395.0K | 0.00% | +22,859 | New |
| Jain Global LLC | 23,639 | $409.2K | 0.01% | +23,639 | New |
| Prelude Capital Management, LLC | 25,628 | $443.6K | 0.04% | −6,372−19.9% | Reduced |
| Voya Investment Management LLC | 25,940 | $449.0K | 0.00% | 00.0% | Unchanged |
| Nomura Asset Management Co Ltd | 28,974 | $501.5K | 0.00% | −7,951−21.5% | Reduced |
| Wexford Capital LP | 30,102 | $521.1K | 0.14% | −51,770−63.2% | Reduced |
| Marshall Wace, LLP | 30,626 | $530.1K | 0.00% | −552,581−94.7% | Reduced |
| Jump Financial, LLC | 30,710 | $531.6K | 0.01% | +30,710 | New |
| Advisor Group Holdings, Inc. | 31,390 | $543.3K | 0.00% | +598+1.9% | Added |
| Sectoral Asset Management Inc | 33,695 | $583.3K | 0.45% | −15,555−31.6% | Reduced |
| Sofinnova Investments, Inc. | 34,952 | $605.0K | 0.05% | +14,060+67.3% | Added |
| ADAR1 Capital Management, LLC | 35,619 | $616.6K | 0.12% | +300+0.8% | Added |
| Exchange Traded Concepts, LLC | 38,923 | $673.8K | 0.01% | −1,512−3.7% | Reduced |
| TrueMark Investments, LLC | 39,217 | $678.8K | 0.18% | −2,910−6.9% | Reduced |
| PFM Health Sciences, LP | 40,400 | $699.3K | 0.05% | +40,400 | New |
| Manufacturers Life Insurance Company, The | 40,737 | $705.2K | 0.00% | −17,505−30.1% | Reduced |
| Alps Advisors Inc | 43,080 | $745.7K | 0.00% | −3,220−7.0% | Reduced |
| TD Asset Management Inc | 43,686 | $756.2K | 0.00% | −45,196−50.8% | Reduced |
| Geode Capital Management, LLC | 45,737 | $791.7K | 0.00% | +32+0.1% | Added |
| Group One Trading, L.P. | 48,917 | $846.8K | 0.04% | +27,350+126.8% | Added |
| Bank of Montreal | 53,235 | $921.5K | 0.00% | +3,062+6.1% | Added |
| Cubist Systematic Strategies, LLC | 54,816 | $948.9K | 0.01% | +54,816 | New |
| Bank of America Corp | 55,438 | $959.6K | 0.00% | +1,253+2.3% | Added |
| Macquarie Group Ltd | 58,000 | $1.00M | 0.00% | 00.0% | Unchanged |
| DAFNA Capital Management LLC | 59,000 | $1.02M | 0.29% | +23,500+66.2% | Added |
| Susquehanna International Group, LLP | 68,167 | $1.18M | 0.00% | −36−0.1% | Reduced |
| Rhenman & Partners Asset Management AB | 70,000 | $1.21M | 0.14% | +70,000 | New |
| Platinum Investment Management Ltd | 74,900 | $1.30M | 0.08% | 00.0% | Unchanged |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 76,863 | $1.33M | 0.00% | −37,129−32.6% | Reduced |
| Boothbay Fund Management, LLC | 77,294 | $1.34M | 0.05% | −5,854−7.0% | Reduced |
| Capital Fund Management S.A. | 79,656 | $1.38M | 0.02% | +12,521+18.7% | Added |
| Banque Pictet & Cie SA | 81,766 | $1.42M | 0.02% | +7,589+10.2% | Added |
| Sphera Funds Management Ltd. | 84,000 | $1.45M | 0.36% | +84,000 | New |
| Point72 Europe (London) LLP | 90,697 | $1.57M | 0.11% | +59,277+188.7% | Added |
| Zimmer Partners, LP | 100,776 | $1.74M | 0.04% | +43,876+77.1% | Added |
| Exome Asset Management LLC | 102,944 | $1.78M | 1.60% | −49,021−32.3% | Reduced |
| Citigroup Inc | 104,975 | $1.82M | 0.00% | +30,891+41.7% | Added |
| Trexquant Investment LP | 120,340 | $2.08M | 0.02% | +67,464+127.6% | Added |
| Jane Street Group, LLC | 120,703 | $2.09M | 0.00% | +4,690+4.0% | Added |
| First Light Asset Management, LLC | 132,380 | $2.29M | 0.26% | −266,475−66.8% | Reduced |
| JPMorgan Chase & Co | 134,239 | $2.32M | 0.00% | +101,924+315.4% | Added |
| CCG Wealth Management, LLC | 150,000 | $2.60M | 1.55% | 00.0% | Unchanged |