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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
122
+38 vs. Q3 2023
Shares held
42.7M
+9.88M (+30.1%) vs. Q3 2023
Total value
$1.74B
+$96.7M (+5.9%) vs. Q3 2023
New holders
55
37 more added
Sold out
17
24 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 122 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 38 institutionsQ2 2023: 48 institutionsQ3 2023: 84 institutionsQ4 2023: 122 institutionsQ1 2024: 119 institutionsQ2 2024: 167 institutionsQ3 2024: 161 institutionsQ4 2024: 165 institutionsQ1 2025: 151 institutionsQ2 2025: 173 institutionsQ3 2025: 158 institutionsQ4 2025: 199 institutionsQ1 2026: 198 institutionsQ2 2026: 191 institutions
Value heldQ4 2023: $1.74B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $346.2MQ2 2023: $699.4MQ3 2023: $1.64BQ4 2023: $1.74BQ1 2024: $1.86BQ2 2024: $2.33BQ3 2024: $2.69BQ4 2024: $1.65BQ1 2025: $990.0MQ2 2025: $1.14BQ3 2025: $1.59BQ4 2025: $4.58BQ1 2026: $3.23BQ2 2026: $3.62B
Institutions holding GPCR and their total value by quarter
QuarterHoldersValue
Q2 2026191$3.62B
Q1 2026198$3.23B
Q4 2025199$4.58B
Q3 2025158$1.59B
Q2 2025173$1.14B
Q1 2025151$990.0M
Q4 2024165$1.65B
Q3 2024161$2.69B
Q2 2024167$2.33B
Q1 2024119$1.86B
Q4 2023122$1.74B
Q3 202384$1.64B
Q2 202348$699.4M
Q1 202338$346.2M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2023.

Institutions holding GPCR in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Wellington Management Group LLP4,372,326$178.2M0.03%+3,504,747+404.0%Added
FMR LLC4,034,584$164.4M0.01%+2,444,249+153.7%Added
Driehaus Capital Management LLC2,599,079$105.9M1.28%+210,203+8.8%Added
Avoro Capital Advisors LLC2,333,333$95.1M1.31%+1,333,333+133.3%Added
Federated Hermes, Inc.2,267,206$92.4M0.23%+1,157,006+104.2%Added
TCG Crossover Management, LLC2,109,584$86.0M9.54%+606,837+40.4%Added
Adage Capital Partners GP, L.L.C.1,756,918$71.6M0.15%−43,005−2.4%Reduced
Price T Rowe Associates Inc1,679,436$68.5M0.01%−834,127−33.2%Reduced
Janus Henderson Group PLC1,544,416$62.8M0.04%−546,907−26.2%Reduced
T. Rowe Price Investment Management, Inc.1,312,195$53.5M0.03%−259,482−16.5%Reduced
Citadel Advisors LLC1,152,985$47.0M0.05%+72,393+6.7%Added
Casdin Capital, LLC1,091,867$44.5M4.39%−166,299−13.2%Reduced
SC China Holding Ltd1,065,226$44.1M5.07%00.0%Unchanged
Avidity Partners Management LP1,080,000$44.0M1.68%+580,000+116.0%Added
Logos Global Management LP1,070,058$43.6M4.85%+570,058+114.0%Added
BlackRock Inc.1,061,058$43.2M0.00%+533,728+101.2%Added
Capital Research Global Investors973,535$39.7M0.01%+628,687+182.3%Added
Capital International Investors850,024$34.6M0.01%+850,024New
Deerfield Management Company, L.P. (Series C)822,813$33.5M0.62%+195,000+31.1%Added
BVF Inc812,988$33.1M0.83%−937,012−53.5%Reduced
Capital World Investors634,160$25.8M0.00%+533,760+531.6%Added
Franklin Resources Inc542,323$22.1M0.01%+291,503+116.2%Added
Ra Capital Management, L.P.486,832$19.8M0.31%+486,832New
Goldman Sachs Group Inc427,735$17.4M0.00%+356,302+498.8%Added
Octagon Capital Advisors LP414,000$16.9M2.70%+414,000New
Boxer Capital, LLC400,000$16.3M0.81%+400,000New
Frazier Life Sciences Management, L.P.317,190$12.9M0.69%+317,190New
Deep Track Capital, LP300,000$12.2M0.43%−1,615,000−84.3%Reduced
Fred Alger Management, LLC291,097$11.9M0.06%+191,757+193.0%Added
Morgan Stanley287,069$11.7M0.00%+263,255+1,105.5%Added
Rock Springs Capital Management LP286,676$11.7M0.29%+286,676New
Braidwell LP280,158$11.4M0.42%+280,158New
ArrowMark Colorado Holdings LLC278,732$11.4M0.13%+228,732+457.5%Added
MPM Oncology Impact Management LP230,696$9.40M2.20%−650.0%Reduced
Candriam Luxembourg S.C.A.210,000$8.56M0.06%+210,000New
Invesco Ltd.195,627$7.97M0.00%+82,534+73.0%Added
Monashee Investment Management LLC191,855$7.82M1.38%−441,911−69.7%Reduced
Woodline Partners LP179,219$7.30M0.08%+9,219+5.4%Added
Alyeska Investment Group, L.P.178,677$7.28M0.05%+178,677New
Sofinnova Investments, Inc.174,838$7.13M0.40%−27,281−13.5%Reduced
TD Asset Management Inc157,258$6.41M0.01%+5,082+3.3%Added
Ghost Tree Capital, LLC150,000$6.11M3.52%+95,000+172.7%Added
Pictet Asset Management Holding SA138,797$5.66M0.01%+138,797New
Victory Capital Management Inc125,447$5.11M0.01%−25,511−16.9%Reduced
Bamco Inc118,333$4.82M0.01%+118,333New
Marshall Wace, LLP105,770$4.31M0.01%−1,748−1.6%Reduced
Schroder Investment Management Group91,145$3.72M0.00%+91,145New
Artal Group S.A.86,600$3.53M0.12%+86,600New
GMT Capital Corp81,700$3.33M0.13%−31,500−27.8%Reduced
Platinum Investment Management Ltd77,093$3.14M0.13%+24,632+47.0%Added
Bank of America Corp76,504$3.12M0.00%+66,630+674.8%Added
HighVista Strategies LLC74,832$3.05M1.11%00.0%Unchanged
Exome Asset Management LLC68,100$2.78M2.74%+68,100New
Ameriprise Financial Inc62,757$2.56M0.00%+62,757New
UBS Group AG59,637$2.43M0.00%+59,637New
Manufacturers Life Insurance Company, The53,204$2.17M0.00%−1,882−3.4%Reduced
Weiss Multi-Strategy Advisers LLC48,914$1.99M0.05%+22,977+88.6%Added
Allspring Global Investments Holdings, LLC48,085$1.96M0.00%+48,085New
Qube Research & Technologies Ltd40,676$1.66M0.00%+40,676New
Jane Street Group, LLC38,798$1.58M0.00%+38,798New
Parkman Healthcare Partners LLC38,678$1.58M0.22%+8,678+28.9%Added
Pier Capital, LLC35,653$1.45M0.21%+35,653New
Wexford Capital LP32,462$1.32M0.28%−35,516−52.2%Reduced
AlphaCentric Advisors LLC30,000$1.22M0.82%+30,000New
Engineers Gate Manager LP29,414$1.20M0.03%+29,414New
E Fund Management Co., Ltd.28,589$1.17M0.07%+28,589New
Russell Investments Group, Ltd.28,393$1.16M0.00%+28,393New
TrueMark Investments, LLC26,322$1.07M1.07%+26,322New
Kennedy Capital Management, Inc.25,876$1.05M0.02%+25,876New
Twinbeech Capital LP24,290$990.1K0.02%+24,290New
Geode Capital Management, LLC22,194$904.6K0.00%+14,403+184.9%Added
Group One Trading, L.P.17,914$730.2K0.02%+17,914New
EFG Asset Management (North America) Corp.17,390$704.6K0.13%+17,390New
Millennium Management LLC16,769$683.5K0.00%−283,105−94.4%Reduced
Citigroup Inc16,680$679.9K0.00%+16,555+13,244.0%Added
Ensign Peak Advisors, Inc16,300$664.4K0.00%00.0%Unchanged
Natixis Advisors, L.P.15,558$634.0K0.00%+15,558New
M&T Bank Corp14,600$595.5K0.00%+14,600New
Ikarian Capital, LLC14,524$592.0K0.16%−123,300−89.5%Reduced
State Street Corp13,936$568.0K0.00%−524−3.6%Reduced
Walleye Trading LLC13,879$565.7K0.01%+13,879New
Prelude Capital Management, LLC13,700$558.4K0.05%+500+3.8%Added
First Trust Advisors LP12,967$528.5K0.00%+12,967New
Simplex Trading, LLC12,322$502.0K0.02%+12,322New
Bellevue Group AG12,300$501.3K0.01%−4,500−26.8%Reduced
Brandywine Managers, LLC12,007$489.4K0.54%+1,007+9.2%Added
Susquehanna International Group, LLP11,702$477.0K0.00%+11,702New
Teachers Retirement System of the State of Kentucky11,656$475.0K0.00%+11,656New
Voya Investment Management LLC9,730$396.6K0.00%−76,744−88.7%Reduced
Temasek Holdings (Private) Ltd9,617$392.0K0.00%00.0%Unchanged
FIL Ltd9,304$379.2K0.00%+695+8.1%Added
Schonfeld Strategic Advisors LLC9,200$375.0K0.00%−15,400−62.6%Reduced
JPMorgan Chase & Co7,846$319.8K0.00%−31,713−80.2%Reduced
EntryPoint Capital, LLC7,835$319.4K0.31%+7,835New
New York State Common Retirement Fund6,800$277.2K0.00%+6,800New
Royal Bank of Canada6,537$267.0K0.00%+6,434+6,246.6%Added
Bayesian Capital Management, LP6,086$248.1K0.03%+6,086New
Raymond James & Associates5,705$232.5K0.00%+5,705New
Cutler Group LP5,100$207.0K0.03%+5,100New
Bleichroeder LP5,000$203.8K0.05%+5,000New