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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Structure Therapeutics Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
198
+1 vs. Q4 2025
Shares held
66.8M
+1.94M (+3.0%) vs. Q4 2025
Total value
$3.23B
−$1.29B (−28.6%) vs. Q4 2025
New holders
41
72 more added
Sold out
40
58 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 198 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 38 institutionsQ2 2023: 48 institutionsQ3 2023: 84 institutionsQ4 2023: 122 institutionsQ1 2024: 119 institutionsQ2 2024: 167 institutionsQ3 2024: 161 institutionsQ4 2024: 165 institutionsQ1 2025: 151 institutionsQ2 2025: 173 institutionsQ3 2025: 158 institutionsQ4 2025: 199 institutionsQ1 2026: 198 institutionsQ2 2026: 191 institutions
Value heldQ1 2026: $3.23B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $346.2MQ2 2023: $699.4MQ3 2023: $1.64BQ4 2023: $1.74BQ1 2024: $1.86BQ2 2024: $2.33BQ3 2024: $2.69BQ4 2024: $1.65BQ1 2025: $990.0MQ2 2025: $1.14BQ3 2025: $1.59BQ4 2025: $4.58BQ1 2026: $3.23BQ2 2026: $3.62B
Institutions holding GPCR and their total value by quarter
QuarterHoldersValue
Q2 2026191$3.62B
Q1 2026198$3.23B
Q4 2025199$4.58B
Q3 2025158$1.59B
Q2 2025173$1.14B
Q1 2025151$990.0M
Q4 2024165$1.65B
Q3 2024161$2.69B
Q2 2024167$2.33B
Q1 2024119$1.86B
Q4 2023122$1.74B
Q3 202384$1.64B
Q2 202348$699.4M
Q1 202338$346.2M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q4 2025.

Institutions holding GPCR in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Huntington National Bank2$960.00%00.0%Unchanged
IMA Wealth, Inc.2$960.00%+2New
Larson Financial Group LLC5$2410.00%00.0%Unchanged
Cullen/Frost Bankers, Inc.8$3860.00%00.0%Unchanged
Allworth Financial LP9$4340.00%00.0%Unchanged
Ancora Advisors, LLC10$4820.00%00.0%Unchanged
US Bancorp10$4820.00%+10New
Smartleaf Asset Management LLC17$7470.00%+17New
Capital Analysts, LLC18$1.00K0.00%00.0%Unchanged
Transamerica Financial Advisors, Inc.22$1.06K0.00%+22New
Rakuten Securities, Inc.60$2.89K0.00%+60New
Basecamp Wealth Advisors LLC84$4.05K0.00%+84New
Signaturefd, LLC100$4.82K0.00%−6,550−98.5%Reduced
SHP Wealth Management100$4.82K0.00%00.0%Unchanged
Farmers & Merchants Investments Inc100$4.82K0.00%+100New
Key Financial Inc100$4.82K0.00%+100New
CWM, LLC125$6.03K0.00%−355−74.0%Reduced
Dynamic Wealth Strategies, LLC150$7.23K0.00%00.0%Unchanged
SOA Wealth Advisors, LLC.200$9.64K0.00%−150−42.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)212$10.2K0.00%+212New
Jones Financial Companies LLLP341$15.7K0.00%−705−67.4%Reduced
North Star Investment Management Corp.330$15.9K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd376$18.1K0.00%+376New
Wolff Wiese Magana LLC400$19.3K0.01%00.0%Unchanged
State of Wyoming433$20.9K0.00%−1,328−75.4%Reduced
EverSource Wealth Advisors, LLC558$26.9K0.00%−20−3.5%Reduced
Sterling Capital Management LLC590$28.4K0.00%+590New
Tower Research Capital LLC (TRC)646$31.1K0.00%+605+1,475.6%Added
Royal Bank of Canada722$35.0K0.00%−9,478−92.9%Reduced
Farther Finance Advisors, LLC931$46.7K0.00%+241+34.9%Added
GAMMA Investing LLC999$48.2K0.00%+69+7.4%Added
Steward Partners Investment Advisory, LLC1,400$67.5K0.00%−1,140−44.9%Reduced
GF Fund Management Co. Ltd.1,500$72.3K0.00%+188+14.3%Added
Nano Cap New Millennium Growth Fund L P1,500$72.3K0.07%+1,500New
Penserra Capital Management LLC1,738$83.0K0.00%+1,738New
Rockefeller Capital Management L.P.2,220$107.0K0.00%+1,489+203.7%Added
Assetmark, Inc2,544$122.6K0.00%+449+21.4%Added
SG Americas Securities, LLC2,649$128.0K0.00%−7,498−73.9%Reduced
The PNC Financial Services Group, Inc.2,854$137.6K0.00%−1,072−27.3%Reduced
Virtus Investment Advisers, Inc.4,065$195.9K0.05%+98+2.5%Added
Arrowpoint Investment Partners (Singapore) Pte. Ltd.4,190$202.0K0.29%+4,190New
E. Ohman J:or Asset Management AB4,518$217.8K0.01%00.0%Unchanged
Invesco Ltd.4,581$220.8K0.00%+1,381+43.2%Added
Toroso Investments, LLC4,643$223.8K0.00%+4,643New
Quadcap Wealth Management, LLC4,729$227.9K0.03%−2,754−36.8%Reduced
Concurrent Investment Advisors, LLC5,000$241.0K0.00%00.0%Unchanged
Jain Global LLC5,772$278.2K0.00%−94,224−94.2%Reduced
Advisory Services Network, LLC5,879$283.4K0.00%+5,879New
PEAK6 LLC6,055$291.9K0.01%−1,900−23.9%Reduced
Mirae Asset Global Investments Co., Ltd.6,411$309.0K0.00%+1,144+21.7%Added
Bellevue Group AG6,803$327.9K0.01%−138,364−95.3%Reduced
Janney Montgomery Scott LLC6,819$329.0K0.00%+6,819New
Scientech Research LLC6,958$335.4K0.28%+6,958New
Parallel Advisors, LLC7,352$354.4K0.01%00.0%Unchanged
Independent Advisor Alliance7,444$358.8K0.00%+2,901+63.9%Added
Vestmark Advisory Solutions, Inc.7,534$363.1K0.00%00.0%Unchanged
Mission Wealth Management, LP7,583$365.5K0.01%−2,000−20.9%Reduced
Cetera Investment Advisers7,720$372.1K0.00%+1,124+17.0%Added
Wells Fargo & Company7,818$376.8K0.00%+2,154+38.0%Added
Axq Capital, LP7,916$381.6K0.05%+7,916New
DnB Asset Management AS8,188$394.7K0.00%−4,451−35.2%Reduced
Allianz Asset Management GmbH8,600$414.5K0.00%−3,400−28.3%Reduced
Cinctive Capital Management LP8,714$420.0K0.03%+8,714New
Seven Fleet Capital Management LP9,000$433.8K0.14%+9,000New
SmartHarvest Portfolios, LLC9,056$436.5K0.18%00.0%Unchanged
Gilbert & Cook, Inc.9,193$443.1K0.06%+3,511+61.8%Added
LPL Financial LLC9,260$446.3K0.00%+1,151+14.2%Added
HighTower Advisors, LLC9,620$463.7K0.00%+300+3.2%Added
Quinn Opportunity Partners LLC10,000$482.0K0.03%−15,000−60.0%Reduced
Russell Investments Group, Ltd.10,701$515.8K0.00%−15,573−59.3%Reduced
BNP Paribas Arbitrage, SA10,879$524.4K0.00%+2,133+24.4%Added
Verdad Advisers, LP11,335$546.3K0.62%+11,335New
Stifel Financial Corp11,342$546.7K0.00%+6,512+134.8%Added
Envestnet Asset Management Inc11,377$548.4K0.00%−193−1.7%Reduced
Brandywine Managers, LLC13,357$643.8K0.38%00.0%Unchanged
Wexford Capital LP13,709$660.8K0.11%−1,126−7.6%Reduced
Gsa Capital Partners LLP13,811$666.0K0.04%+13,811New
China Universal Asset Management Co., Ltd.13,824$666.3K0.05%+2,936+27.0%Added
MML Investors Services, LLC13,887$669.4K0.00%+6,062+77.5%Added
SEI Investments Co13,990$674.3K0.00%−913−6.1%Reduced
Sectoral Asset Management Inc14,102$710.8K0.59%−9,770−40.9%Reduced
Aquatic Capital Management LLC14,814$714.0K0.02%+14,814New
Teachers Retirement System of the State of Kentucky17,297$834.0K0.01%00.0%Unchanged
Persistent Asset Partners Ltd18,263$880.3K0.34%+15,827+649.7%Added
Barclays PLC19,188$924.9K0.00%+11,355+145.0%Added
Citigroup Inc20,494$987.8K0.00%+13,159+179.4%Added
CenterBook Partners LP21,237$1.02M0.05%+21,237New
Walleye Capital LLC21,360$1.03M0.01%+21,358+1,067,900.0%Added
Squarepoint Ops LLC22,646$1.09M0.00%+22,646New
Exchange Traded Concepts, LLC25,378$1.22M0.01%−603−2.3%Reduced
DCF Advisers, LLC27,500$1.33M0.50%−2,500−8.3%Reduced
Verition Fund Management LLC28,074$1.35M0.01%−50,075−64.1%Reduced
Avidity Partners Management LP30,000$1.45M0.29%+30,000New
XTX Topco Ltd30,921$1.49M0.03%+11,728+61.1%Added
Capital Fund Management S.A.32,436$1.56M0.01%+32,436New
Nomura Asset Management Co Ltd32,790$1.58M0.00%+3,638+12.5%Added
TrueMark Investments, LLC34,377$1.66M0.32%+484+1.4%Added
Private Capital Advisors, Inc.34,389$1.66M0.19%+27,041+368.0%Added
Mariner, LLC34,480$1.66M0.00%−9,675−21.9%Reduced
PSquared Asset Management AG35,000$1.69M0.59%+35,000New