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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

Q1 2026 vs. Q4 2025

How the institutions holding Structure Therapeutics Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026All holders in Q4 2025

13F holders of GPCR: Q4 2025 compared with Q1 2026
MeasureQ4 2025Of which not filed for Q1 2026Q1 2026Change
Holders1992198+1
Shares65.8M886.8K66.8M+1.94M (+3.0%)
Value$4.58B$61.7M$3.23B−$1.29B (−28.6%)

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (41)

Institutions that held Structure Therapeutics Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to GPCR in Q1 2026
InstitutionSharesValue% of portfolio
Capitolis Liquid Global Markets LLC1,151,300$55.5M0.35%
Paradigm Biocapital Advisors LP545,287$26.3M0.54%
SEB Asset Management AB245,043$11.8M0.05%
Pentwater Capital Management LP245,000$11.8M0.08%
Cormorant Asset Management, LP175,000$8.44M0.43%
Holocene Advisors, LP159,009$7.66M0.02%
Davern Capital Partners, LP126,461$6.10M1.67%
Jump Financial, LLC107,857$5.20M0.08%
Schroder Investment Management Group118,225$5.19M0.00%
Jones Hill Capital LP100,593$4.85M1.04%
Qube Research & Technologies Ltd73,599$3.55M0.01%
Diadema Partners LP72,234$3.48M1.44%
PSquared Asset Management AG35,000$1.69M0.59%
Capital Fund Management S.A.32,436$1.56M0.01%
Avidity Partners Management LP30,000$1.45M0.29%
Squarepoint Ops LLC22,646$1.09M0.00%
CenterBook Partners LP21,237$1.02M0.05%
Aquatic Capital Management LLC14,814$714.0K0.02%
Gsa Capital Partners LLP13,811$666.0K0.04%
Verdad Advisers, LP11,335$546.3K0.62%
Seven Fleet Capital Management LP9,000$433.8K0.14%
Cinctive Capital Management LP8,714$420.0K0.03%
Axq Capital, LP7,916$381.6K0.05%
Scientech Research LLC6,958$335.4K0.28%
Janney Montgomery Scott LLC6,819$329.0K0.00%
Advisory Services Network, LLC5,879$283.4K0.00%
Toroso Investments, LLC4,643$223.8K0.00%
Arrowpoint Investment Partners (Singapore) Pte. Ltd.4,190$202.0K0.29%
Penserra Capital Management LLC1,738$83.0K0.00%
Nano Cap New Millennium Growth Fund L P1,500$72.3K0.07%
Sterling Capital Management LLC590$28.4K0.00%
Caitong International Asset Management Co., Ltd376$18.1K0.00%
Zurcher Kantonalbank (Zurich Cantonalbank)212$10.2K0.00%
Farmers & Merchants Investments Inc100$4.82K0.00%
Key Financial Inc100$4.82K0.00%
Basecamp Wealth Advisors LLC84$4.05K0.00%
Rakuten Securities, Inc.60$2.89K0.00%
Transamerica Financial Advisors, Inc.22$1.06K0.00%
Smartleaf Asset Management LLC17$7470.00%
US Bancorp10$4820.00%
IMA Wealth, Inc.2$960.00%

Sold out (40)

Institutions that held Structure Therapeutics Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Institutions that sold out of GPCR in Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Citadel Advisors LLC772,518$53.7M
Farallon Capital Management, L.L.C.454,000$31.6M
EcoR1 Capital, LLC334,380$23.3M
Capricorn Fund Managers Ltd252,600$17.6M
Jane Street Group, LLC147,217$10.2M
Alyeska Investment Group, L.P.115,000$8.00M
RTW Investments, LP100,000$6.96M
Susquehanna Fundamental Investments, LLC99,617$6.93M
SummitTX Capital, L.P.94,671$6.58M
Simplex Trading, LLC92,668$6.45M
Longaeva Partners L.P.60,000$4.17M
Integral Health Asset Management, LLC50,000$3.48M
ACT Capital Management, LLC38,500$2.68M
EAM Investors, LLC38,054$2.65M
Vestal Point Capital, LP35,000$2.43M
Maven Securities LTD20,000$1.39M
Acadian Asset Management LLC17,606$1.22M
J. Goldman & Co LP13,601$946.0K
Quadrature Capital Ltd12,761$887.5K
Y-Intercept (Hong Kong) Ltd10,132$704.7K
Bleichroeder LP10,000$695.5K
PSP Research LLC6,719$467.3K
Blueshift Asset Management, LLC5,213$362.6K
Ikarian Capital, LLC4,824$335.5K
Graham Capital Management, L.P.4,778$332.3K
Gabelli Funds LLC4,000$278.2K
Merit Financial Group, LLC3,688$256.5K
Northern Trust Corp3,645$253.5K
Bank of New York Mellon Corp3,604$250.6K
Profund Advisors LLC3,507$243.9K
CIBC World Markets Inc.3,248$225.9K
ProShare Advisors LLC2,957$205.7K
Banque Cantonale Vaudoise2,945$205.0K
Police & Firemen's Retirement System of New Jersey1,829$127.2K
Country Trust Bank500$34.8K
Private Wealth Management Group, LLC196$13.6K
Daiwa Securities Group Inc.186$13.0K
Northwestern Mutual Wealth Management Co60$4.17K
Bessemer Group Inc29$2.00K
Bellevue Asset Management, LLC15$1.04K

Not filed for Q1 2026 yet (2)

Institutions that held Structure Therapeutics Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding GPCR in Q4 2025 that haven't filed for Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Capitolis Liquid Global Markets LLC878,300$61.1M
Janney Capital Management LLC8,513$592.0K