Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 165
- +6 vs. Q3 2024
- Shares held
- 60.9M
- −620.5K (−1.0%) vs. Q3 2024
- Total value
- $1.65B
- −$1.04B (−38.7%) vs. Q3 2024
- New holders
- 29
- 66 more added
- Sold out
- 23
- 49 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Teachers Retirement System of the State of Kentucky | 17,651 | $479.0K | 0.00% | 00.0% | Unchanged |
| HighVista Strategies LLC | 17,561 | $476.3K | 0.18% | −14,157−44.6% | Reduced |
| Simplex Trading, LLC | 17,346 | $470.0K | 0.01% | −3,913−18.4% | Reduced |
| Engineers Gate Manager LP | 16,880 | $457.8K | 0.01% | −8,595−33.7% | Reduced |
| J. Goldman & Co LP | 16,873 | $457.6K | 0.02% | +16,873 | New |
| Natixis Advisors, L.P. | 14,459 | $392.0K | 0.00% | −12,216−45.8% | Reduced |
| Griffin Asset Management, Inc. | 14,450 | $391.9K | 0.05% | 00.0% | Unchanged |
| Walleye Trading LLC | 13,485 | $365.7K | 0.01% | +4,909+57.2% | Added |
| EntryPoint Capital, LLC | 13,260 | $359.6K | 0.15% | +8,095+156.7% | Added |
| China Universal Asset Management Co., Ltd. | 12,634 | $342.6K | 0.03% | +1,174+10.2% | Added |
| Quinn Opportunity Partners LLC | 12,000 | $325.4K | 0.02% | 00.0% | Unchanged |
| Walleye Capital LLC | 11,656 | $316.1K | 0.00% | +11,656 | New |
| LPL Financial LLC | 11,485 | $311.5K | 0.00% | +646+6.0% | Added |
| BNP Paribas Arbitrage, SA | 11,218 | $304.2K | 0.00% | +11,218 | New |
| Brandywine Managers, LLC | 11,057 | $299.9K | 0.32% | 00.0% | Unchanged |
| State Street Corp | 10,527 | $285.5K | 0.00% | −1,768−14.4% | Reduced |
| Wells Fargo & Company | 10,103 | $274.0K | 0.00% | +6,763+202.5% | Added |
| Bleichroeder LP | 10,000 | $271.2K | 0.07% | 00.0% | Unchanged |
| PEAK6 LLC | 9,445 | $256.1K | 0.01% | +9,445 | New |
| Cinctive Capital Management LP | 9,065 | $245.8K | 0.01% | −23,029−71.8% | Reduced |
| Janney Capital Management LLC | 9,007 | $244.0K | 0.02% | +2,405+36.4% | Added |
| Spire Wealth Management | 8,949 | $242.7K | 0.01% | +8,949 | New |
| Allianz Asset Management GmbH | 8,800 | $238.7K | 0.00% | 00.0% | Unchanged |
| Quadcap Wealth Management, LLC | 7,851 | $212.9K | 0.03% | −949−10.8% | Reduced |
| Envestnet Asset Management Inc | 7,403 | $200.8K | 0.00% | +843+12.9% | Added |
| Caption Management, LLC | 5,600 | $151.9K | 0.01% | −2,144−27.7% | Reduced |
| SG Americas Securities, LLC | 5,445 | $148.0K | 0.00% | −2,911−34.8% | Reduced |
| Vestcor Inc | 4,700 | $127.0K | 0.00% | +4,700 | New |
| Jones Financial Companies LLLP | 4,228 | $114.7K | 0.00% | +971+29.8% | Added |
| Headlands Technologies LLC | 4,160 | $112.8K | 0.01% | +4,160 | New |
| Pictet & Cie (Europe) SA | 4,143 | $112.4K | 0.00% | −549−11.7% | Reduced |
| Tower Research Capital LLC (TRC) | 4,076 | $110.5K | 0.00% | +3,549+673.4% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,566 | $99.7K | 0.00% | −218−5.8% | Reduced |
| The PNC Financial Services Group, Inc. | 3,277 | $88.9K | 0.00% | −42−1.3% | Reduced |
| Penserra Capital Management LLC | 3,107 | $84.0K | 0.00% | +135+4.5% | Added |
| Assetmark, Inc | 2,271 | $61.6K | 0.00% | +953+72.3% | Added |
| Virtus ETF Advisers LLC | 2,242 | $60.8K | 0.02% | +455+25.5% | Added |
| Steward Partners Investment Advisory, LLC | 2,114 | $57.3K | 0.00% | +56+2.7% | Added |
| Jefferies Financial Group Inc. | 2,000 | $54.2K | 0.00% | −5,000−71.4% | Reduced |
| FNY Investment Advisers, LLC | 1,500 | $40.0K | 0.02% | +1,500 | New |
| GF Fund Management Co. Ltd. | 1,251 | $33.9K | 0.00% | +1,251 | New |
| GAMMA Investing LLC | 1,149 | $31.2K | 0.00% | +1,122+4,155.6% | Added |
| Antipodes Partners Ltd | 1,034 | $28.0K | 0.00% | +553+115.0% | Added |
| R Squared Ltd | 680 | $18.4K | 0.02% | +680 | New |
| Rhumbline Advisers | 450 | $12.2K | 0.00% | 00.0% | Unchanged |
| North Star Investment Management Corp. | 330 | $8.95K | 0.00% | −650−66.3% | Reduced |
| Clear Street Markets LLC | 246 | $6.67K | 0.00% | +246 | New |
| Daiwa Securities Group Inc. | 226 | $6.00K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 191 | $5.18K | 0.00% | −21−9.9% | Reduced |
| Caitong International Asset Management Co., Ltd | 186 | $5.04K | 0.00% | +186 | New |
| CWM, LLC | 100 | $3.00K | 0.00% | +100 | New |
| US Bancorp | 101 | $2.74K | 0.00% | +88+676.9% | Added |
| Signaturefd, LLC | 100 | $2.71K | 0.00% | 00.0% | Unchanged |
| Vermillion Wealth Management, Inc. | 100 | $2.71K | 0.00% | +100 | New |
| CoreCap Advisors, LLC | 77 | $2.09K | 0.00% | +77 | New |
| Clearstead Advisors, LLC | 67 | $1.82K | 0.00% | 00.0% | Unchanged |
| Fairfield Financial Advisors, LTD | 59 | $1.60K | 0.00% | 00.0% | Unchanged |
| Washington Trust Advisors, Inc. | 41 | $1.11K | 0.00% | 00.0% | Unchanged |
| Aventura Private Wealth, LLC | 28 | $759 | 0.00% | +28 | New |
| Federation des caisses Desjardins du Quebec | 20 | $542 | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 10 | $271 | 0.00% | +10 | New |
| Cullen/Frost Bankers, Inc. | 8 | $217 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 2 | $54 | 0.00% | 00.0% | Unchanged |
| Point72 Asia (Singapore) Pte. Ltd. | 1 | $23 | 0.00% | +1 | New |
| Capital Analysts, LLC | 18 | $0 | 0.00% | 00.0% | Unchanged |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −1,198,000−100.0% | Sold out |
| T. Rowe Price Investment Management, Inc. | 0 | $0 | 0.00% | −715,968−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −430,900−100.0% | Sold out |
| Boxer Capital, LLC | 0 | $0 | 0.00% | −400,000−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −250,000−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −144,500−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −71,615−100.0% | Sold out |
| Altium Capital Management LP | 0 | $0 | 0.00% | −70,000−100.0% | Sold out |
| Blue Owl Capital Holdings LP | 0 | $0 | 0.00% | −65,000−100.0% | Sold out |
| Plustick Management LLC | 0 | $0 | 0.00% | −45,000−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −40,706−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −34,852−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −30,464−100.0% | Sold out |
| AlphaCentric Advisors LLC | 0 | $0 | 0.00% | −26,000−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −16,703−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −11,938−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −7,660−100.0% | Sold out |
| Shay Capital LLC | 0 | $0 | 0.00% | −7,500−100.0% | Sold out |
| Gilbert & Cook, Inc. | 0 | $0 | 0.00% | −5,682−100.0% | Sold out |
| Crestline Management, LP | 0 | $0 | 0.00% | −5,310−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −5,163−100.0% | Sold out |
| Dearborn Partners LLC | 0 | $0 | 0.00% | −4,600−100.0% | Sold out |
| Truvestments Capital LLC | 0 | $0 | 0.00% | −82−100.0% | Sold out |
| PEAK6 Investments LLC | – | – | – | – | Not filed |
| Planning Capital Management Corp | – | – | – | – | Not filed |