Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 165
- +6 vs. Q3 2024
- Shares held
- 60.9M
- −620.5K (−1.0%) vs. Q3 2024
- Total value
- $1.65B
- −$1.04B (−38.7%) vs. Q3 2024
- New holders
- 29
- 66 more added
- Sold out
- 23
- 49 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital Analysts, LLC | 18 | $0 | 0.00% | 00.0% | Unchanged |
| Point72 Asia (Singapore) Pte. Ltd. | 1 | $23 | 0.00% | +1 | New |
| Huntington National Bank | 2 | $54 | 0.00% | 00.0% | Unchanged |
| Cullen/Frost Bankers, Inc. | 8 | $217 | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 10 | $271 | 0.00% | +10 | New |
| Federation des caisses Desjardins du Quebec | 20 | $542 | 0.00% | 00.0% | Unchanged |
| Aventura Private Wealth, LLC | 28 | $759 | 0.00% | +28 | New |
| Washington Trust Advisors, Inc. | 41 | $1.11K | 0.00% | 00.0% | Unchanged |
| Fairfield Financial Advisors, LTD | 59 | $1.60K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 67 | $1.82K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 77 | $2.09K | 0.00% | +77 | New |
| Signaturefd, LLC | 100 | $2.71K | 0.00% | 00.0% | Unchanged |
| Vermillion Wealth Management, Inc. | 100 | $2.71K | 0.00% | +100 | New |
| US Bancorp | 101 | $2.74K | 0.00% | +88+676.9% | Added |
| CWM, LLC | 100 | $3.00K | 0.00% | +100 | New |
| Caitong International Asset Management Co., Ltd | 186 | $5.04K | 0.00% | +186 | New |
| National Bank of Canada | 191 | $5.18K | 0.00% | −21−9.9% | Reduced |
| Daiwa Securities Group Inc. | 226 | $6.00K | 0.00% | 00.0% | Unchanged |
| Clear Street Markets LLC | 246 | $6.67K | 0.00% | +246 | New |
| North Star Investment Management Corp. | 330 | $8.95K | 0.00% | −650−66.3% | Reduced |
| Rhumbline Advisers | 450 | $12.2K | 0.00% | 00.0% | Unchanged |
| R Squared Ltd | 680 | $18.4K | 0.02% | +680 | New |
| Antipodes Partners Ltd | 1,034 | $28.0K | 0.00% | +553+115.0% | Added |
| GAMMA Investing LLC | 1,149 | $31.2K | 0.00% | +1,122+4,155.6% | Added |
| GF Fund Management Co. Ltd. | 1,251 | $33.9K | 0.00% | +1,251 | New |
| FNY Investment Advisers, LLC | 1,500 | $40.0K | 0.02% | +1,500 | New |
| Jefferies Financial Group Inc. | 2,000 | $54.2K | 0.00% | −5,000−71.4% | Reduced |
| Steward Partners Investment Advisory, LLC | 2,114 | $57.3K | 0.00% | +56+2.7% | Added |
| Virtus ETF Advisers LLC | 2,242 | $60.8K | 0.02% | +455+25.5% | Added |
| Assetmark, Inc | 2,271 | $61.6K | 0.00% | +953+72.3% | Added |
| Penserra Capital Management LLC | 3,107 | $84.0K | 0.00% | +135+4.5% | Added |
| The PNC Financial Services Group, Inc. | 3,277 | $88.9K | 0.00% | −42−1.3% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 3,566 | $99.7K | 0.00% | −218−5.8% | Reduced |
| Tower Research Capital LLC (TRC) | 4,076 | $110.5K | 0.00% | +3,549+673.4% | Added |
| Pictet & Cie (Europe) SA | 4,143 | $112.4K | 0.00% | −549−11.7% | Reduced |
| Headlands Technologies LLC | 4,160 | $112.8K | 0.01% | +4,160 | New |
| Jones Financial Companies LLLP | 4,228 | $114.7K | 0.00% | +971+29.8% | Added |
| Vestcor Inc | 4,700 | $127.0K | 0.00% | +4,700 | New |
| SG Americas Securities, LLC | 5,445 | $148.0K | 0.00% | −2,911−34.8% | Reduced |
| Caption Management, LLC | 5,600 | $151.9K | 0.01% | −2,144−27.7% | Reduced |
| Envestnet Asset Management Inc | 7,403 | $200.8K | 0.00% | +843+12.9% | Added |
| Quadcap Wealth Management, LLC | 7,851 | $212.9K | 0.03% | −949−10.8% | Reduced |
| Allianz Asset Management GmbH | 8,800 | $238.7K | 0.00% | 00.0% | Unchanged |
| Spire Wealth Management | 8,949 | $242.7K | 0.01% | +8,949 | New |
| Janney Capital Management LLC | 9,007 | $244.0K | 0.02% | +2,405+36.4% | Added |
| Cinctive Capital Management LP | 9,065 | $245.8K | 0.01% | −23,029−71.8% | Reduced |
| PEAK6 LLC | 9,445 | $256.1K | 0.01% | +9,445 | New |
| Bleichroeder LP | 10,000 | $271.2K | 0.07% | 00.0% | Unchanged |
| Wells Fargo & Company | 10,103 | $274.0K | 0.00% | +6,763+202.5% | Added |
| State Street Corp | 10,527 | $285.5K | 0.00% | −1,768−14.4% | Reduced |
| Brandywine Managers, LLC | 11,057 | $299.9K | 0.32% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 11,218 | $304.2K | 0.00% | +11,218 | New |
| LPL Financial LLC | 11,485 | $311.5K | 0.00% | +646+6.0% | Added |
| Walleye Capital LLC | 11,656 | $316.1K | 0.00% | +11,656 | New |
| Quinn Opportunity Partners LLC | 12,000 | $325.4K | 0.02% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 12,634 | $342.6K | 0.03% | +1,174+10.2% | Added |
| EntryPoint Capital, LLC | 13,260 | $359.6K | 0.15% | +8,095+156.7% | Added |
| Walleye Trading LLC | 13,485 | $365.7K | 0.01% | +4,909+57.2% | Added |
| Griffin Asset Management, Inc. | 14,450 | $391.9K | 0.05% | 00.0% | Unchanged |
| Natixis Advisors, L.P. | 14,459 | $392.0K | 0.00% | −12,216−45.8% | Reduced |
| J. Goldman & Co LP | 16,873 | $457.6K | 0.02% | +16,873 | New |
| Engineers Gate Manager LP | 16,880 | $457.8K | 0.01% | −8,595−33.7% | Reduced |
| Simplex Trading, LLC | 17,346 | $470.0K | 0.01% | −3,913−18.4% | Reduced |
| HighVista Strategies LLC | 17,561 | $476.3K | 0.18% | −14,157−44.6% | Reduced |
| Teachers Retirement System of the State of Kentucky | 17,651 | $479.0K | 0.00% | 00.0% | Unchanged |
| M&T Bank Corp | 18,110 | $491.6K | 0.00% | +9,055+100.0% | Added |
| UBS Oconnor LLC | 19,520 | $529.4K | 0.01% | +1,520+8.4% | Added |
| Sofinnova Investments, Inc. | 20,892 | $566.6K | 0.04% | −17,900−46.1% | Reduced |
| Money Concepts Capital Corp | 21,031 | $570.4K | 0.04% | +848+4.2% | Added |
| Group One Trading, L.P. | 21,567 | $584.9K | 0.02% | +15,758+271.3% | Added |
| Mariner, LLC | 24,530 | $665.3K | 0.00% | +24,530 | New |
| Voya Investment Management LLC | 25,940 | $703.5K | 0.00% | −20,830−44.5% | Reduced |
| Twinbeech Capital LP | 28,268 | $766.6K | 0.01% | +7,220+34.3% | Added |
| Advisor Group Holdings, Inc. | 30,792 | $835.0K | 0.00% | +30,272+5,821.5% | Added |
| Point72 Europe (London) LLP | 31,420 | $852.1K | 0.05% | −13,413−29.9% | Reduced |
| Prelude Capital Management, LLC | 32,000 | $867.8K | 0.07% | +7,023+28.1% | Added |
| JPMorgan Chase & Co | 32,315 | $876.4K | 0.00% | −1,621−4.8% | Reduced |
| Russell Investments Group, Ltd. | 34,671 | $940.3K | 0.00% | +2,888+9.1% | Added |
| ADAR1 Capital Management, LLC | 35,319 | $957.9K | 0.20% | +35,319 | New |
| DAFNA Capital Management LLC | 35,500 | $962.8K | 0.24% | +1,500+4.4% | Added |
| Nomura Asset Management Co Ltd | 36,925 | $1.00M | 0.00% | +7,496+25.5% | Added |
| Exchange Traded Concepts, LLC | 40,435 | $1.10M | 0.02% | −666−1.6% | Reduced |
| TrueMark Investments, LLC | 42,127 | $1.14M | 0.36% | −3,353−7.4% | Reduced |
| NEOS Investment Management LLC | 44,343 | $1.20M | 0.03% | +29,542+199.6% | Added |
| Tema ETFs LLC | 44,343 | $1.20M | 0.50% | +44,343 | New |
| Geode Capital Management, LLC | 45,705 | $1.24M | 0.00% | +480+1.1% | Added |
| Alps Advisors Inc | 46,300 | $1.26M | 0.01% | +46,300 | New |
| Sectoral Asset Management Inc | 49,250 | $1.34M | 0.89% | +24,855+101.9% | Added |
| Bank of Montreal | 50,173 | $1.36M | 0.00% | +3,671+7.9% | Added |
| Trexquant Investment LP | 52,876 | $1.43M | 0.02% | +45,235+592.0% | Added |
| Bank of America Corp | 54,185 | $1.47M | 0.00% | −43,206−44.4% | Reduced |
| Zimmer Partners, LP | 56,900 | $1.54M | 0.03% | −154,200−73.0% | Reduced |
| Macquarie Group Ltd | 58,000 | $1.57M | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 58,242 | $1.58M | 0.00% | −28,600−32.9% | Reduced |
| Fred Alger Management, LLC | 66,662 | $1.81M | 0.01% | −51−0.1% | Reduced |
| Capital Fund Management S.A. | 67,135 | $1.82M | 0.02% | +17,007+33.9% | Added |
| Susquehanna International Group, LLP | 68,203 | $1.85M | 0.00% | +4,422+6.9% | Added |
| Citigroup Inc | 74,084 | $2.01M | 0.00% | +72,533+4,676.5% | Added |
| Banque Pictet & Cie SA | 74,177 | $2.01M | 0.02% | −6,876−8.5% | Reduced |
| Platinum Investment Management Ltd | 74,900 | $2.03M | 0.12% | +17,670+30.9% | Added |