Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 199
- +44 vs. Q3 2025
- Shares held
- 65.8M
- +8.91M (+15.7%) vs. Q3 2025
- Total value
- $4.58B
- +$2.99B (+188.4%) vs. Q3 2025
- New holders
- 72
- 52 more added
- Sold out
- 28
- 63 more reduced
3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vestal Point Capital, LP | 35,000 | $2.43M | 0.09% | +35,000 | New |
| TrueMark Investments, LLC | 33,893 | $2.36M | 0.45% | −968−2.8% | Reduced |
| Bank of America Corp | 31,678 | $2.20M | 0.00% | +17,899+129.9% | Added |
| DCF Advisers, LLC | 30,000 | $2.09M | 0.69% | −34,250−53.3% | Reduced |
| Nomura Asset Management Co Ltd | 29,152 | $2.03M | 0.01% | +3,296+12.7% | Added |
| Russell Investments Group, Ltd. | 26,274 | $1.83M | 0.00% | +26,274 | New |
| Exchange Traded Concepts, LLC | 25,981 | $1.81M | 0.02% | −32,241−55.4% | Reduced |
| Quinn Opportunity Partners LLC | 25,000 | $1.74M | 0.08% | −17,000−40.5% | Reduced |
| Sectoral Asset Management Inc | 23,872 | $1.66M | 1.33% | −198,000−89.2% | Reduced |
| Maven Securities LTD | 20,000 | $1.39M | 0.18% | +20,000 | New |
| XTX Topco Ltd | 19,193 | $1.33M | 0.04% | +19,193 | New |
| Acadian Asset Management LLC | 17,606 | $1.22M | 0.00% | +17,606 | New |
| Teachers Retirement System of the State of Kentucky | 17,297 | $1.20M | 0.01% | +6,546+60.9% | Added |
| SEI Investments Co | 14,903 | $1.04M | 0.00% | +14,903 | New |
| Wexford Capital LP | 14,835 | $1.03M | 0.27% | +14,835 | New |
| J. Goldman & Co LP | 13,601 | $946.0K | 0.04% | +13,601 | New |
| Brandywine Managers, LLC | 13,357 | $929.0K | 0.46% | +2,300+20.8% | Added |
| JPMorgan Chase & Co | 12,956 | $901.1K | 0.00% | −45,192−77.7% | Reduced |
| Quadrature Capital Ltd | 12,761 | $887.5K | 0.01% | +12,761 | New |
| DnB Asset Management AS | 12,639 | $879.0K | 0.00% | −249−1.9% | Reduced |
| Allianz Asset Management GmbH | 12,000 | $834.6K | 0.00% | +12,000 | New |
| Envestnet Asset Management Inc | 11,570 | $804.7K | 0.00% | −650−5.3% | Reduced |
| China Universal Asset Management Co., Ltd. | 10,888 | $757.3K | 0.06% | +444+4.3% | Added |
| Royal Bank of Canada | 10,200 | $709.0K | 0.00% | −93−0.9% | Reduced |
| SG Americas Securities, LLC | 10,147 | $706.0K | 0.00% | −29,553−74.4% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 10,132 | $704.7K | 0.02% | +10,132 | New |
| Bleichroeder LP | 10,000 | $695.5K | 0.12% | −10,000−50.0% | Reduced |
| Mission Wealth Management, LP | 9,583 | $666.5K | 0.01% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 9,320 | $648.2K | 0.00% | +320+3.6% | Added |
| SmartHarvest Portfolios, LLC | 9,056 | $629.8K | 0.22% | +9,056 | New |
| Susquehanna International Group, LLP | 8,999 | $625.9K | 0.00% | −204,609−95.8% | Reduced |
| BNP Paribas Arbitrage, SA | 8,746 | $608.3K | 0.00% | −81,685−90.3% | Reduced |
| Schonfeld Strategic Advisors LLC | 8,727 | $607.0K | 0.00% | +8,727 | New |
| D. E. Shaw & Co., Inc. | 8,623 | $599.7K | 0.00% | −27,723−76.3% | Reduced |
| Janney Capital Management LLC | 8,513 | $592.0K | 0.04% | −5,205−37.9% | Reduced |
| LPL Financial LLC | 8,109 | $564.0K | 0.00% | −14,894−64.7% | Reduced |
| PEAK6 LLC | 7,955 | $553.3K | 0.02% | −3,045−27.7% | Reduced |
| Barclays PLC | 7,833 | $544.8K | 0.00% | +4,060+107.6% | Added |
| MML Investors Services, LLC | 7,825 | $544.2K | 0.00% | +7,825 | New |
| Vestmark Advisory Solutions, Inc. | 7,534 | $524.0K | 0.01% | +7,534 | New |
| Parallel Advisors, LLC | 7,352 | $511.3K | 0.01% | −912−11.0% | Reduced |
| Private Capital Advisors, Inc. | 7,348 | $511.1K | 0.05% | −47,837−86.7% | Reduced |
| Citigroup Inc | 7,335 | $510.1K | 0.00% | +5,879+403.8% | Added |
| PSP Research LLC | 6,719 | $467.3K | 0.41% | +6,719 | New |
| Signaturefd, LLC | 6,650 | $462.5K | 0.01% | 00.0% | Unchanged |
| Cetera Investment Advisers | 6,596 | $458.8K | 0.00% | +6,596 | New |
| Gilbert & Cook, Inc. | 5,682 | $395.2K | 0.05% | +5,682 | New |
| Wells Fargo & Company | 5,664 | $393.9K | 0.00% | −394−6.5% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 5,267 | $366.3K | 0.00% | +1,211+29.9% | Added |
| Blueshift Asset Management, LLC | 5,213 | $362.6K | 0.10% | +5,213 | New |
| Quadcap Wealth Management, LLC | 7,483 | $354.8K | 0.04% | +7,483 | New |
| Concurrent Investment Advisors, LLC | 5,000 | $347.8K | 0.00% | +5,000 | New |
| Stifel Financial Corp | 4,830 | $335.9K | 0.00% | +4,830 | New |
| Ikarian Capital, LLC | 4,824 | $335.5K | 0.04% | −158,413−97.0% | Reduced |
| Graham Capital Management, L.P. | 4,778 | $332.3K | 0.01% | +4,778 | New |
| Independent Advisor Alliance | 4,543 | $316.0K | 0.01% | +4,543 | New |
| E. Ohman J:or Asset Management AB | 4,518 | $314.2K | 0.01% | +4,518 | New |
| Gabelli Funds LLC | 4,000 | $278.2K | 0.00% | +4,000 | New |
| Virtus Investment Advisers, Inc. | 3,967 | $275.9K | 0.07% | −1,154−22.5% | Reduced |
| The PNC Financial Services Group, Inc. | 3,926 | $273.1K | 0.00% | −902−18.7% | Reduced |
| Merit Financial Group, LLC | 3,688 | $256.5K | 0.00% | +3,688 | New |
| Northern Trust Corp | 3,645 | $253.5K | 0.00% | +3,645 | New |
| Bank of New York Mellon Corp | 3,604 | $250.6K | 0.00% | +3,604 | New |
| Profund Advisors LLC | 3,507 | $243.9K | 0.01% | +3,507 | New |
| CIBC World Markets Inc. | 3,248 | $225.9K | 0.00% | +3,248 | New |
| Invesco Ltd. | 3,200 | $222.6K | 0.00% | −440,537−99.3% | Reduced |
| ProShare Advisors LLC | 2,957 | $205.7K | 0.00% | +2,957 | New |
| Banque Cantonale Vaudoise | 2,945 | $205.0K | 0.01% | +2,945 | New |
| Steward Partners Investment Advisory, LLC | 2,540 | $176.7K | 0.00% | −100−3.8% | Reduced |
| Persistent Asset Partners Ltd | 2,436 | $169.4K | 0.08% | +2,436 | New |
| Assetmark, Inc | 2,095 | $145.7K | 0.00% | −289−12.1% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 1,829 | $127.2K | 0.00% | +1,829 | New |
| State of Wyoming | 1,761 | $122.5K | 0.01% | +403+29.7% | Added |
| GF Fund Management Co. Ltd. | 1,312 | $91.3K | 0.00% | +34+2.7% | Added |
| Jones Financial Companies LLLP | 1,046 | $72.7K | 0.00% | +859+459.4% | Added |
| GAMMA Investing LLC | 930 | $64.7K | 0.00% | +112+13.7% | Added |
| Rockefeller Capital Management L.P. | 731 | $50.8K | 0.00% | −11−1.5% | Reduced |
| Farther Finance Advisors, LLC | 690 | $48.0K | 0.00% | +20+3.0% | Added |
| EverSource Wealth Advisors, LLC | 578 | $40.2K | 0.00% | −493−46.0% | Reduced |
| Country Trust Bank | 500 | $34.8K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 480 | $33.0K | 0.00% | +125+35.2% | Added |
| Wolff Wiese Magana LLC | 400 | $27.8K | 0.02% | +114+39.9% | Added |
| SOA Wealth Advisors, LLC. | 350 | $24.3K | 0.00% | +350 | New |
| North Star Investment Management Corp. | 330 | $23.0K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 196 | $13.6K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 186 | $13.0K | 0.00% | −40−17.7% | Reduced |
| Dynamic Wealth Strategies, LLC | 150 | $10.4K | 0.01% | −400−72.7% | Reduced |
| SHP Wealth Management | 100 | $6.96K | 0.00% | +100 | New |
| Northwestern Mutual Wealth Management Co | 60 | $4.17K | 0.00% | +60 | New |
| Tower Research Capital LLC (TRC) | 41 | $2.85K | 0.00% | −353−89.6% | Reduced |
| Bessemer Group Inc | 29 | $2.00K | 0.00% | 00.0% | Unchanged |
| Bellevue Asset Management, LLC | 15 | $1.04K | 0.00% | +15 | New |
| Capital Analysts, LLC | 18 | $1.00K | 0.00% | 00.0% | Unchanged |
| Ancora Advisors, LLC | 10 | $695 | 0.00% | +10 | New |
| Allworth Financial LP | 9 | $626 | 0.00% | +9 | New |
| Cullen/Frost Bankers, Inc. | 8 | $556 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 5 | $348 | 0.00% | +2+66.7% | Added |
| Walleye Capital LLC | 2 | $139 | 0.00% | −4,488−100.0% | Reduced |
| Huntington National Bank | 2 | $139 | 0.00% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 0 | $0 | 0.00% | −1,517,418−100.0% | Sold out |